TWAS hub - IL7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1530	0.0330	8.3e-15	0.159	0.139	0.156	0.156	0.153	6.1e-19	1.4e-16	1.5e-18	1.7e-18	3.3e-18
2	GTEx	Brain Cerebellar Hemisphere	0.2580	0.0770	3.0e-04	0.161	NA	0.179	NA	0.169	6.4e-05	NA	2.4e-05	NA	4.2e-05
3	GTEx	Brain Cerebellum	0.2370	0.0620	1.9e-06	0.309	NA	0.310	NA	0.286	8.1e-10	NA	7.4e-10	NA	4.2e-09
4	GTEx	Brain Hypothalamus	0.2360	0.0930	9.7e-03	-0.004	NA	-0.007	NA	0.009	4.1e-01	NA	5.2e-01	NA	1.9e-01
5	GTEx	Liver	0.2830	0.1080	7.5e-03	0.144	NA	0.128	NA	0.096	8.3e-05	NA	2.1e-04	NA	1.2e-03
6	GTEx	Nerve Tibial	0.1506	0.0518	7.9e-05	0.122	NA	0.079	NA	0.108	6.2e-09	NA	2.9e-06	NA	4.7e-08
7	GTEx	Ovary	0.2570	0.0930	1.4e-03	0.205	NA	0.158	NA	0.164	9.1e-06	NA	1.1e-04	NA	7.7e-05
8	NTR	Blood	0.0320	0.0107	2.4e-05	0.003	0.016	0.008	0.016	0.005	3.3e-02	5.4e-06	9.7e-04	6.0e-06	6.2e-03
9	TCGA	Brain Lower Grade Glioma	0.0668	0.0342	3.0e-04	0.029	0.035	0.030	NA	0.030	2.7e-04	7.2e-05	2.3e-04	NA	1.9e-04
10	TCGA	Thyroid Carcinoma	0.0390	0.0200	2.8e-03	0.019	0.017	0.024	NA	0.020	5.1e-03	7.8e-03	2.1e-03	NA	4.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Noisy workplace	5.2	6.4	11.8	-3.1	-2.4	-3.3	-1.1	-1.7	-3.3	-3.4	-0.7	-1.7	-2.9
Medication: Ibuprofen (e.g. Nurofen)	4.7	5.9	11.3	3.2	2.8	3.1	1.8	-0.1	3.0	3.4	0.8	1.4	2.3
Chronic bronchitis/emphysema (father)	4.6	5.4	9.2	-2.6	-1.8	-2.7	1.4	1.9	-2.8	-2.5	-1.6	-3.0	-2.3
Medication: Ibuprofen	4.5	5.4	9.8	3.0	2.5	2.8	2.1	-0.2	2.8	3.1	0.7	1.6	2.4
Tinnitus: Yes, now most or all of the time	4.4	5.1	7.3	-2.5	-2.7	-2.7	-0.9	0.6	-2.7	-2.6	-1.8	-2.2	-2.7
Shortness of breath walking on level ground	3.9	4.6	7.2	-2.0	-2.5	-2.7	-1.4	1.5	-2.5	-2.6	-1.3	-2.5	-1.9
Blood White Count	3.6	27.0	51.3	-5.4	-5.8	-7.0	-2.0	-0.1	-7.0	-7.2	-2.6	-1.4	-6.7
Overall health rating	3.5	7.5	12.7	-3.0	-3.2	-3.6	-0.1	1.9	-3.4	-3.4	-1.3	-2.4	-2.9
Ever highly irritable/argumentative for 2 days	3.0	3.6	6.3	-2.0	-1.9	-2.1	-0.7	1.0	-2.0	-2.1	-1.4	-2.5	-2.3
Fluid intelligence score	2.9	5.9	9.0	2.7	2.6	2.8	1.1	-0.7	2.8	2.9	1.8	3.0	2.6
Age at first live birth	2.8	5.0	8.3	2.4	2.9	2.3	1.6	-1.1	2.2	2.5	2.3	1.6	2.7
Other serious medical condition/disability diagnosed by doctor	2.4	3.2	6.7	-2.6	-1.4	-2.3	0.4	0.5	-2.3	-2.5	-1.2	-1.3	-1.6
Age at last live birth	2.4	3.4	6.9	2.0	2.2	2.0	1.4	-0.5	2.0	2.3	1.4	1.1	2.6
Primary Biliary Cirrhosis	2.3	3.3	6.4	-2.1	-1.7	-2.4	-0.3	1.3	-2.5	-2.5	-0.3	-1.7	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.5	3.8	1.7	1.8	1.8	1.3	-1.2	1.9	1.9	0.7	1.2	1.6
Length of working week for main job	2.2	2.4	6.7	1.9	2.1	1.3	0.7	-0.8	1.4	1.3	2.6	0.4	1.9
Mouth/teeth dental problems: Loose teeth	2.2	2.6	5.0	-1.6	-1.4	-1.9	-2.2	-0.1	-1.8	-2.2	-0.9	-1.2	-1.7
Lupus	2.1	3.2	5.7	-2.2	-1.8	-2.2	-1.6	-0.2	-2.3	-2.4	-0.0	-1.0	-2.1
Mouth/teeth dental problems	2.1	3.1	6.6	1.6	1.6	2.3	0.5	-1.2	2.1	2.6	1.8	0.7	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.1	2.5	5.0	1.7	1.8	1.5	2.2	-0.5	1.7	1.9	0.2	1.8	1.5
Eye problems/disorders: Glaucoma	2.1	2.5	3.8	1.7	1.8	1.8	1.5	0.9	1.7	2.0	1.1	1.1	1.9
Myopia	2.1	3.0	5.7	2.1	1.4	2.0	1.5	0.6	2.0	2.1	0.2	2.4	1.6
Breastfed as a baby	2.0	2.5	4.3	-2.0	-1.2	-1.9	-0.6	-1.0	-1.9	-2.1	0.6	-1.7	-1.6
Number of full sisters	2.0	2.4	5.3	-1.7	-2.2	-1.2	-1.9	0.4	-1.2	-1.3	0.4	-1.5	-2.3
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.0	1.8	0.8	2.0	1.2	0.9	2.0	1.7	-1.1	1.4	1.4
Verbal and Numeric Reasoning (VNR)	1.8	4.3	6.6	2.3	1.9	2.5	1.2	-0.1	2.4	2.6	1.8	2.4	2.2
Age when periods started (menarche)	1.8	4.4	8.1	-2.6	-2.4	-2.4	-1.7	-0.1	-2.4	-2.3	0.7	-2.8	-1.9
Prospective memory result	1.8	2.3	4.3	-2.0	-0.9	-1.4	-1.5	-0.3	-1.4	-2.1	-1.2	-1.6	-1.8
Illnesses of siblings: Diabetes	1.8	2.2	5.0	-1.4	-2.2	-1.6	-0.7	-0.4	-1.6	-1.5	-0.1	-2.0	-1.8
Neck or shoulder pain in last month	1.7	2.4	6.9	1.2	1.5	1.2	0.1	-0.1	1.2	1.4	2.1	2.6	1.9
Medication for hormone replacement therapy	1.6	1.8	11.0	0.5	1.6	0.6	-1.0	-0.0	0.5	0.6	3.3	0.6	1.3
Breast cancer (self-reported)	1.6	1.9	4.2	-2.0	-0.7	-1.7	-0.2	2.1	-1.6	-1.6	-0.6	-1.4	-0.6
Relative age voice broke	1.5	2.3	7.8	-1.2	-1.5	-1.1	-2.8	-1.0	-1.3	-1.5	-1.0	-1.5	-1.5
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	4.6	1.2	2.1	1.3	1.0	1.6	1.2	1.7	-0.2	1.4	1.5
Mouth/teeth dental problems: Dentures	1.5	2.5	5.6	-1.8	-1.6	-2.0	-0.6	0.4	-1.9	-2.4	-0.2	-1.4	-2.0
Exposure to tobacco smoke at home	1.5	1.6	4.2	-0.9	-1.3	-1.2	-2.1	-1.6	-1.3	-1.4	-0.1	-0.6	-1.3
Medication: Gliclazide	1.5	1.7	4.5	-1.4	-1.3	-0.9	-2.1	-0.9	-0.8	-1.6	-0.4	-0.9	-1.9
Financial situation satisfaction	1.5	1.9	4.4	-1.4	-1.0	-1.4	-0.4	2.1	-1.4	-1.5	-1.3	-1.7	-0.9
Intelligence (Savage-Jansen 2018)	1.4	4.5	7.7	2.2	2.1	2.4	0.9	-0.5	2.4	2.0	2.8	2.6	2.0
Number of live births	1.4	2.0	4.6	-1.9	-1.4	-1.6	-0.6	0.2	-1.5	-1.8	-0.6	-1.1	-2.1
Glaucoma (self-reported)	1.4	1.6	3.6	1.4	1.1	1.5	1.6	-0.1	1.4	1.9	0.8	0.7	1.1
Chronic bronchitis/emphysema (mother)	1.4	1.6	2.2	-1.4	-1.1	-1.4	0.3	1.1	-1.5	-1.3	-1.4	-1.3	-1.3
Depressed Affect (Nagel 2018)	1.3	2.7	6.5	-1.1	-2.5	-1.8	1.6	-1.3	-1.7	-1.5	-0.4	-1.0	-2.3
Alzheimer’s Disease (in mother)	1.3	1.6	4.2	-2.0	-0.6	-1.5	-1.6	0.9	-1.5	-1.3	-0.5	-0.5	-1.1
Alzheimer’s Disease (including proxy)	1.3	1.9	4.8	-2.2	-0.7	-1.7	-1.5	-0.3	-1.7	-1.7	-0.6	-0.4	-1.6
Sensitivity / hurt feelings	1.3	2.3	3.8	-1.6	-1.8	-1.9	1.4	-0.5	-1.8	-1.5	0.4	-1.2	-1.9
Bilateral oophorectomy (both ovaries removed)	1.3	1.6	4.5	1.1	1.1	1.3	0.7	0.0	1.3	1.4	-0.1	2.1	1.8
Medication: Levothyroxine sodium	1.3	2.1	6.6	-0.9	-2.3	-0.5	0.1	-2.6	-0.6	-1.1	-1.0	-1.5	-1.9
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.5	1.4	1.2	1.2	1.4	0.0	1.2	1.3	1.6	0.7	1.5
Leg pain on walking	1.3	1.7	5.1	-1.5	-1.1	-1.4	-1.1	0.3	-1.3	-1.5	-2.2	-0.4	-1.0
Alcohol drinker status: Never	1.3	1.6	3.3	1.5	0.5	1.5	1.3	-0.3	1.6	1.4	-0.4	1.8	1.1
Ever used hormone-replacement therapy (HRT)	1.2	1.5	7.0	0.9	1.3	0.8	2.6	-0.5	0.8	0.9	1.5	0.4	0.6
Commuting to job workplace: Car/motor vehicle	1.2	1.3	2.8	-1.3	-1.7	-1.0	-1.2	0.8	-1.0	-1.2	-0.5	-1.6	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.9	1.0	0.7	1.0	2.0	-1.3	1.0	1.2	-0.7	1.4	0.9
Illnesses of father: None of the above (group 1)	1.2	1.4	2.9	1.1	1.5	1.0	0.7	-1.2	1.1	1.1	0.9	1.3	1.7
Supplements: Zinc	1.1	1.2	5.7	0.3	0.5	1.0	-1.8	-2.4	0.9	0.5	-0.2	0.6	0.3
Loud music exposure frequency	1.1	1.1	3.7	-1.4	-0.2	-1.2	-0.5	1.9	-1.3	-0.9	1.2	-0.2	-0.3
Worry too long after embarrassment	1.1	1.9	5.2	-1.0	-1.8	-1.5	-0.0	0.7	-1.5	-1.5	-2.3	-0.7	-1.5
Chest pain or discomfort	1.1	1.5	8.8	-0.7	0.1	-0.3	1.4	3.0	-0.3	-0.2	-1.8	0.7	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.4	5.1	-1.5	-2.2	-2.1	0.1	-1.0	-2.1	-1.7	-0.3	-1.2	-1.8
Schizophrenia vs Biploar Disorder	1.0	1.3	6.7	-1.6	-0.0	-0.5	-0.5	2.6	-0.6	-0.4	-1.4	-0.8	-0.1
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.7	-0.7	-1.0	-0.9	-0.3	-0.3	-0.9	-1.1	-1.6	-1.5	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.6	-1.4	-1.4	-1.6	-0.5	-0.2	-1.5	-1.6	0.1	-0.6	-1.3
Allergy	1.0	2.3	6.4	-1.4	-2.5	-1.1	-1.8	-0.9	-1.2	-0.8	-1.3	-1.8	-1.4
Asthma	1.0	2.0	3.5	1.0	1.9	1.6	0.5	1.8	1.7	1.2	0.2	1.5	1.7
Pulse wave reflection index	1.0	1.3	3.5	1.5	1.3	0.9	0.2	0.8	0.9	1.0	-0.3	1.9	1.4
Wheeze or whistling in the chest in last year	1.0	1.8	3.7	-1.7	-0.6	-1.2	0.1	1.9	-1.2	-1.5	-1.8	-0.9	-1.5
Qualifications: nursing, teaching	1.0	1.5	3.1	1.8	1.0	1.7	-1.0	-0.2	1.7	1.3	-0.8	0.9	1.0
Commuting to job workplace: Public transport	1.0	1.2	6.0	0.7	1.0	0.3	2.5	1.4	0.1	0.8	1.2	0.0	0.6
Alcohol drinker status: Previous	1.0	1.2	2.7	-1.1	-1.3	-1.1	-1.6	0.1	-1.2	-1.4	0.3	-0.9	-0.9
Crohns Disease (2017)	0.9	2.0	4.4	0.8	1.4	1.6	1.5	0.5	1.5	1.9	0.3	2.1	1.4
Ulcerative Colitis	0.9	1.4	4.1	1.1	0.3	0.8	-1.1	0.2	0.9	0.8	1.8	2.0	1.0
Diabetes (father)	0.9	1.1	3.5	-0.8	-0.9	-0.8	-0.8	1.0	-0.8	-0.9	-1.9	-0.6	-1.3
Fed-up feelings	0.9	1.6	3.9	-0.7	-2.0	-1.2	0.9	-2.0	-1.0	-0.9	0.0	-0.5	-1.9
Hair/balding pattern: Pattern 3	0.9	1.3	4.5	-0.8	-1.3	-0.5	-1.1	1.9	-0.4	-0.8	-2.1	-0.5	-0.8
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.4	0.5	1.4	0.7	1.6	1.8	0.7	1.0	-0.1	1.0	1.5
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	10.6	0.5	-1.4	1.0	0.9	-3.3	0.9	0.3	-1.5	-0.3	-0.6
Comparative body size at age 10	0.9	2.5	7.8	2.0	-0.0	1.9	-1.1	-2.8	1.9	1.6	0.2	1.1	0.7
Average weekly red wine intake	0.9	1.3	4.1	-1.1	-0.4	-1.1	-0.7	1.7	-1.2	-0.8	-0.5	-2.0	-0.9
Loneliness, isolation	0.9	1.3	3.6	-0.9	-1.2	-1.3	1.9	0.7	-1.2	-0.9	0.0	-1.2	-1.1
Ever had bowel cancer screening	0.9	1.1	4.3	-0.6	1.0	-0.3	1.8	2.1	-0.3	-0.4	-0.2	1.3	0.3
Medication: Aspirin	0.9	1.2	2.2	-1.3	-0.7	-1.5	-1.4	0.6	-1.5	-1.3	-1.0	-0.4	-0.7
Miserableness	0.9	1.6	3.3	-1.3	-1.1	-1.8	0.4	-0.5	-1.7	-1.7	0.0	-1.0	-1.5
Guilty feelings	0.9	1.3	2.5	-0.8	-1.3	-1.2	-0.3	-0.9	-1.3	-1.3	0.1	-1.6	-1.5
Fractured/broken bones in last 5 years	0.9	1.2	6.2	0.6	0.9	0.3	0.9	-1.1	0.4	0.5	2.5	1.2	0.9
Unable to work because of sickness or disability	0.9	1.2	1.8	-1.2	-1.2	-1.3	-1.3	0.8	-1.3	-1.3	-0.6	-0.2	-1.1
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.3	-1.2	-0.9	-1.3	-0.7	-0.6	-1.5	-1.5	0.1	-0.8	-0.9
Relative age of first facial hair	0.8	1.7	3.5	-1.2	-1.8	-1.0	-1.9	-0.9	-1.1	-0.9	-0.5	-1.3	-1.5
Average weekly fortified wine intake	0.8	0.9	4.3	-0.6	-0.9	-0.3	-2.1	0.4	-0.3	-0.6	-1.7	0.3	-0.4
Multivitamins +/- minerals	0.8	1.0	2.7	-1.2	-0.6	-1.0	-0.9	1.6	-1.0	-1.0	-0.2	-1.5	-0.3
Time employed in main current job	0.8	0.9	1.6	0.7	1.2	0.8	-0.7	1.1	0.8	0.7	-0.9	1.1	1.2
Happiness	0.8	1.0	2.1	-1.1	-1.4	-0.6	-0.2	0.5	-0.6	-0.8	-1.4	-1.4	-0.9
Medication: Aspirin	0.8	1.1	2.9	-1.2	-0.6	-1.3	-1.7	-0.1	-1.3	-1.2	-1.0	-0.1	-0.7
Eye problems/disorders: Cataract	0.8	0.9	1.7	-1.0	-0.9	-1.2	-1.3	0.6	-1.1	-1.1	-0.1	-1.0	-0.7
Cholesterol lowering medication	0.8	1.1	2.9	1.1	0.3	0.8	-1.7	1.7	0.9	0.8	-1.3	0.3	0.4
Basal cell carcinoma (self-reported)	0.8	1.0	5.3	-0.4	-1.0	-0.7	1.0	-2.3	-0.6	-0.6	0.2	-0.2	-1.0
Neuroticism (Nagel 2018)	0.7	1.6	4.7	-0.8	-2.2	-1.4	1.2	-0.5	-1.3	-1.2	-0.5	-0.5	-1.9
Irritable Bowel Disease (IBD)	0.7	1.6	6.5	1.2	0.7	1.4	0.6	0.0	1.4	1.5	0.5	2.5	1.0
Breast Cancer	0.7	1.7	5.2	0.5	2.3	0.9	-0.2	1.7	0.8	1.3	0.5	1.0	2.1
Allergy or Eczema	0.7	1.9	5.5	1.3	2.4	0.7	0.4	1.6	0.6	0.7	1.2	1.9	1.6
Medication: Metformin	0.7	0.9	1.8	-1.2	-0.7	-0.9	-1.2	1.4	-0.9	-1.0	-0.6	-0.3	-1.0
Stomach or abdominal pain in last month	0.7	0.9	2.4	-1.6	-0.1	-1.3	0.1	-0.3	-1.3	-1.2	1.2	-0.1	-0.6
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	5.1	-0.4	1.5	-0.5	0.1	0.0	-0.6	-0.2	2.3	-0.1	0.6
Number of incorrect matches in round	0.7	1.2	2.5	0.4	1.4	1.3	0.6	0.5	1.2	1.5	-1.6	0.3	1.2
Nervous feelings	0.7	1.3	2.3	-1.1	-0.8	-1.4	-0.3	1.4	-1.3	-1.5	0.9	-1.1	-0.9
Pain all over the body in last month	0.7	0.7	3.4	-0.7	-0.8	-0.7	0.1	-0.3	-0.7	-0.8	0.3	-1.9	-1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.5	4.7	0.5	1.6	0.9	0.3	2.2	0.9	1.4	-1.0	0.7	1.4
Medication: Lansoprazole	0.7	0.7	3.0	0.3	0.0	0.4	1.4	-1.7	0.4	0.5	-0.1	1.4	0.1
Exposure to tobacco smoke outside home	0.7	0.9	2.9	-0.6	-0.6	-1.1	-1.7	-0.7	-1.1	-0.9	0.4	-0.8	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	3.1	0.8	1.1	0.8	-0.6	1.4	0.9	0.6	-1.3	1.8	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	1.5	-1.0	-0.5	-1.1	0.6	0.1	-1.2	-1.2	1.1	-0.7	-1.0
Asthma (self-reported)	0.7	1.3	2.5	0.8	1.6	1.3	0.3	1.6	1.4	1.0	0.0	1.2	1.3
Hearing aid user	0.7	0.8	1.7	1.0	0.3	1.2	0.8	-0.6	1.3	1.1	-0.7	0.5	0.7
High cholesterol (Self-reported)	0.7	1.3	8.1	-0.4	-0.6	-0.5	-1.5	2.8	-0.3	-0.3	-1.4	0.2	0.1
Major Depression (MDD)	0.6	0.7	2.2	0.3	1.5	0.5	-0.0	1.2	0.6	0.5	-0.2	0.9	1.3
Bipolar Disorder (2011)	0.6	0.6	4.0	-0.1	-0.0	-0.1	2.0	-1.2	-0.2	-0.1	0.2	0.4	-0.2
Hypothyroidism (self reported)	0.6	1.4	6.7	-0.1	-1.4	0.4	1.2	-2.6	0.4	-0.2	-1.4	-0.6	-1.1
Neuroticism	0.6	1.4	4.1	-0.7	-2.0	-1.2	1.3	-0.6	-1.2	-1.0	-1.0	-0.3	-1.5
Vitamin and mineral supplements	0.6	0.8	1.1	1.1	0.8	0.8	0.8	-0.9	0.8	1.0	0.8	1.0	0.8
Qualifications: CSEs or equivalent	0.6	0.8	2.9	-1.0	-0.4	-0.9	-1.7	-0.4	-0.8	-1.2	0.1	-0.6	-0.5
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.2	1.1	2.0	0.6	1.2	1.0	0.7	0.7	0.2	1.3	1.2
Hearing difficulty/problems with background noise	0.6	0.9	4.4	0.7	0.2	0.6	1.3	-0.7	0.5	0.8	-2.1	0.9	0.2
Lung cancer (father)	0.6	0.7	2.3	1.5	0.9	1.0	0.4	-0.6	1.0	1.1	0.1	0.6	0.3
Birth weight of first child	0.6	1.2	2.7	1.4	1.0	1.6	0.2	-0.2	1.6	1.2	-0.9	0.6	0.8
Medication: Amlodipine	0.6	0.8	4.4	0.7	0.7	0.6	0.9	2.1	0.7	0.6	-0.1	0.4	0.6
Angina (self-reported)	0.6	0.8	3.9	-0.2	-0.9	-1.0	-0.4	0.8	-0.9	-0.6	-2.0	-0.5	-0.4
Illnesses of father: Heart disease	0.6	0.8	2.1	-0.4	-1.3	-0.6	-1.4	0.0	-0.7	-0.6	0.3	-0.9	-1.4
Long-standing illness, disability or infirmity	0.6	0.9	2.4	-0.8	-0.9	-1.4	0.1	0.5	-1.3	-1.5	0.6	-0.3	-0.8
Commuting to job workplace: Walk	0.6	0.7	1.5	-0.7	0.2	-1.1	1.2	1.2	-1.1	-0.8	0.5	0.1	-0.0
Back pain experienced in last month	0.6	0.9	5.1	0.3	0.9	0.1	2.3	0.3	0.2	0.3	0.5	1.4	0.8
Irritability	0.6	1.0	1.9	-1.1	-1.2	-1.3	-0.1	0.6	-1.4	-1.0	-0.7	-0.0	-1.2
Supplements: Calcium	0.6	0.6	2.7	-1.0	-0.5	-0.4	-1.7	-0.3	-0.2	-0.6	0.2	-1.0	-0.6
Bipolar Disorder (2018)	0.5	0.8	4.1	0.4	1.1	0.4	2.0	-0.6	0.4	0.6	0.5	0.6	0.9
Bipolar Disorder or Schizophrenia	0.5	1.1	2.7	0.0	1.6	0.6	1.3	1.2	0.7	0.7	-0.4	0.9	1.6
Depression (Nagel 2018)	0.5	0.7	1.6	-1.1	-1.3	-1.0	0.6	-0.2	-1.0	-0.9	-0.4	-0.4	-1.0
Schizophrenia (2018)	0.5	0.9	3.7	-0.3	1.2	0.5	0.1	1.9	0.6	0.5	-0.9	0.7	1.4
Body Mass Index (BMI) (2010)	0.5	0.7	1.4	1.2	0.7	0.9	0.5	-0.6	0.8	1.1	-0.5	1.1	0.9
Mean Putamen Volume	0.5	0.6	2.6	0.3	-0.7	0.2	-0.4	-1.5	0.3	-0.0	1.6	0.0	0.3
HDL Cholesterol	0.5	0.9	4.6	0.6	0.6	0.2	1.4	2.1	0.2	0.3	0.9	0.2	0.9
Neuroticism (2016)	0.5	0.7	1.1	-1.0	-1.0	-1.1	-0.7	0.9	-0.9	-0.6	-0.3	-0.7	-0.7
Rheumatoid Arthritis	0.5	0.6	1.4	0.6	1.2	0.6	0.4	-0.7	0.6	0.5	0.8	1.2	0.9
BMI	0.5	2.7	10.0	-0.7	-2.0	-1.3	-2.1	0.5	-1.3	-1.3	-3.2	-0.2	-1.5
Chronotype (morning person)	0.5	1.2	2.8	-1.1	-1.1	-1.5	-0.1	1.7	-1.5	-1.0	-0.8	-0.5	-0.8
Angina	0.5	0.7	2.9	-0.3	-0.7	-1.0	-0.3	0.7	-0.9	-0.6	-1.7	-0.5	-0.4
Medication: Co-codamol	0.5	0.6	1.3	-0.8	-0.6	-0.8	-0.8	0.5	-0.8	-0.9	0.6	-1.1	-0.6
Supplements: Glucosamine	0.5	0.7	1.5	0.8	0.8	0.9	0.4	0.1	1.0	1.1	0.5	0.8	1.2
Alcohol usually taken with meals	0.5	0.8	2.5	0.6	1.1	0.7	0.6	1.6	0.6	1.1	-0.0	0.5	1.2
Had other major operations	0.5	0.6	3.4	0.2	0.6	-0.0	1.8	-0.0	-0.0	0.4	1.0	-0.4	0.6
Financial difficulties in last 2 years	0.5	0.7	3.9	0.3	-0.5	-0.1	-2.0	1.1	-0.0	-0.6	-1.1	0.2	-0.0
Pulse wave Arterial Stiffness index	0.5	0.5	3.4	-0.0	1.2	-0.1	-0.2	0.2	-0.1	-0.2	-0.1	1.9	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.0	-1.4	0.6	-1.2	0.8	1.1	-1.1	-0.9	-0.1	-0.7	-0.5
Gout (self-reported)	0.5	0.7	2.9	0.8	0.6	0.6	1.1	0.2	0.7	0.8	0.5	1.7	0.8
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.8	-1.1	-0.5	-0.9	-0.3	0.3	-0.9	-1.3	0.0	-0.9	-0.6
Birth weight	0.5	1.1	2.6	1.0	0.8	1.5	0.1	-0.5	1.6	1.3	-0.2	1.6	0.6
Pulse wave peak to peak time	0.5	0.6	3.7	-0.1	-1.2	0.1	0.4	-0.1	0.0	0.1	0.2	-1.9	-0.6
Medication: Blood pressure	0.5	0.8	3.7	-0.6	-1.1	-0.8	0.9	1.9	-0.8	-0.7	-0.4	-0.3	-0.3
Comparative height size at age 10	0.5	2.8	8.2	1.9	1.6	1.8	2.9	-1.7	1.8	1.5	0.2	1.1	0.9
Had major operations	0.5	0.6	3.1	-0.7	-0.5	-0.5	-0.7	1.8	-0.5	-0.8	-0.3	0.4	-0.2
Smoking status: Previous	0.5	0.8	3.4	-0.4	0.6	-0.6	0.5	1.8	-0.6	-0.4	-0.2	-1.6	-0.3
Friendships satisfaction	0.5	0.6	2.4	-1.0	-0.8	-0.7	0.3	1.6	-0.8	-0.5	-0.3	-0.1	-0.3
Medication for cholesterol	0.5	0.8	4.0	0.0	0.4	-0.0	2.0	-1.4	-0.1	-0.2	-0.6	1.2	0.2
Smoking status: Current	0.5	0.7	3.7	0.4	0.7	0.6	0.9	0.2	0.8	0.7	0.2	1.9	0.9
Mother’s age at death	0.5	0.6	1.0	0.9	0.6	0.9	0.9	-0.7	1.0	0.7	0.5	0.6	0.8
Supplements: Fish oil (including cod liver oil)	0.5	0.6	3.5	0.3	0.0	0.3	-0.9	1.9	0.4	0.2	-1.0	0.3	0.5
Medication: Paracetamol	0.5	0.8	2.6	-1.1	-1.3	-0.9	-0.1	0.4	-0.9	-0.8	-1.6	0.1	-0.7
Medication: Lisinopril	0.5	0.6	1.2	-0.7	-1.1	-0.8	-0.2	-1.0	-0.7	-0.8	0.7	0.2	-0.9
Age started oral contraceptive pill	0.5	0.6	2.2	0.4	0.8	0.7	1.5	0.7	0.7	0.7	-0.2	0.5	0.7
Heart attack/myocardial infarction (self-reported)	0.5	0.7	2.8	0.4	1.1	0.5	0.3	0.1	0.4	0.6	-1.0	1.7	1.0
Prostate Cancer	0.4	0.6	2.9	-0.2	-0.1	-0.5	-1.5	1.7	-0.3	-0.8	0.2	-0.0	0.4
HbA1C	0.4	0.4	1.2	-0.3	-0.7	-0.7	1.1	-0.7	-0.6	-0.7	-0.3	-0.4	-0.7
LDL Cholesterol	0.4	0.6	3.3	-0.7	-0.8	0.1	0.9	-1.8	0.1	-0.1	0.3	0.0	-0.9
Schizophrenia (2014)	0.4	1.0	5.6	-0.4	1.0	0.5	0.7	2.4	0.6	0.4	-0.2	0.3	1.2
Smoking Status	0.4	1.0	1.7	0.8	1.2	1.1	0.2	1.3	1.3	1.0	0.5	0.6	1.1
Cardiovascular Disease	0.4	1.2	5.9	-0.9	-1.1	-0.9	-0.3	2.4	-0.7	-0.6	-1.3	-0.2	-0.3
Respiratory disease	0.4	0.9	1.9	0.9	1.4	1.2	-0.8	0.2	1.2	0.7	0.7	1.1	1.0
Ever had hysterectomy (womb removed)	0.4	0.4	1.5	-0.5	-1.2	0.0	0.0	-1.0	0.1	-0.2	-0.8	-0.6	-0.8
Systolic blood pressure, automated reading	0.4	1.2	2.8	0.6	1.7	1.1	1.0	0.6	1.2	1.4	0.4	0.9	1.4
Serious illness, injury or assault to yourself	0.4	0.4	1.0	-1.0	0.1	-0.7	0.6	0.9	-0.8	-1.0	-0.0	0.2	-0.2
High blood pressure (mother)	0.4	0.6	2.3	0.3	0.5	0.3	1.0	1.5	0.3	0.7	0.9	0.1	0.9
Hair/balding pattern: Pattern 2	0.4	0.5	1.0	0.9	-0.1	0.9	0.8	-0.4	1.0	0.8	0.5	0.9	0.6
Heart attack	0.4	0.5	2.2	0.2	1.2	0.3	-0.0	0.2	0.3	0.5	-0.8	1.5	0.9
Medication: Ramipril	0.4	0.5	2.1	0.1	0.1	0.0	-1.3	0.8	-0.0	0.1	1.5	-0.1	0.6
Alcohol intake versus 10 years previously	0.4	0.6	2.1	-0.0	-1.0	-0.4	0.2	0.1	-0.4	-0.2	-1.3	-0.8	-1.5
Medication: Paracetamol	0.4	0.7	2.2	-0.9	-0.8	-1.0	0.1	0.5	-1.0	-0.8	-1.5	0.2	-0.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.5	0.8	1.0	1.1	-1.2	-0.9	1.0	0.9	0.4	0.2	0.3
Health satisfaction	0.4	0.5	2.1	-0.8	-0.4	-0.3	0.7	1.4	-0.1	-0.2	-1.3	0.3	-0.2
Qualifications: College or University degree	0.4	1.3	3.1	1.3	1.8	1.2	0.2	1.1	1.2	1.4	0.7	0.0	1.3
Medication: Allopurinol	0.4	0.5	2.5	0.2	-1.0	0.1	-1.1	-1.6	0.2	0.2	0.0	0.0	-0.8
Family relationship satisfaction	0.4	0.5	2.1	-0.6	0.5	-0.4	-0.1	1.4	-0.4	-0.5	0.9	0.7	0.8
Hypertension (Self-reported)	0.4	1.1	3.4	-1.0	-1.1	-0.9	-0.4	1.8	-0.8	-0.9	-0.6	-1.4	-0.7
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.2	0.6	1.1	0.9	0.7	0.3	0.9	1.0	0.4	-0.1	0.3
Osteoarthritis (self-reported)	0.4	0.5	4.3	-0.1	-0.1	-0.0	-0.1	-0.1	0.0	-0.1	-2.1	-0.8	-0.7
Number of self-reported non-cancer illnesses	0.4	0.7	2.4	-0.9	-0.6	-0.9	-0.8	1.5	-0.9	-1.0	0.0	0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.1	0.0	-0.2	-0.7	0.8	0.8	-0.7	-0.2	-1.4	-0.2	-0.2
Risk taking	0.4	0.5	1.5	-0.3	0.8	0.4	0.9	-0.3	0.4	0.8	-1.2	0.8	0.6
Pain experienced in last month	0.4	0.6	2.0	-0.8	-0.8	-0.6	-1.4	0.1	-0.7	-0.8	0.4	-0.8	-0.8
Alzheimer’s Disease (in father)	0.3	0.3	0.8	-0.5	-0.1	0.0	-0.9	-0.9	0.1	-0.1	-0.8	0.2	-0.8
Ulcerative Colitis (UC)	0.3	0.6	3.9	0.7	0.1	0.4	-0.2	0.4	0.5	0.4	0.7	2.0	0.5
Coronary Artery Disease (CAD)	0.3	0.3	1.5	-0.6	0.0	-0.1	1.2	-0.2	-0.0	0.1	-1.1	0.1	0.1
Crohns Disease (2012)	0.3	0.5	1.5	0.8	-0.3	0.7	1.2	-0.2	0.7	1.1	-0.7	0.6	0.2
Fasting Glucose	0.3	0.4	2.1	-0.3	-0.3	-0.3	0.7	-1.4	-0.4	-0.5	0.4	-0.2	-0.6
Triglycerides	0.3	0.5	1.9	-0.7	-0.2	-0.5	0.5	-1.3	-0.6	-0.5	-1.4	0.4	-0.4
Blood Platelet Count	0.3	3.7	7.6	2.5	1.3	2.2	1.1	-2.8	2.2	1.7	0.6	2.3	1.6
Blood Red Count	0.3	2.6	5.3	-0.8	-2.3	-1.8	-0.4	-0.5	-1.9	-1.7	-2.2	-0.3	-2.3
Average weekly spirits intake	0.3	0.4	0.9	-0.5	0.0	-0.7	-0.8	-1.0	-0.7	-0.8	0.4	-0.3	-0.5
Hearing difficulty/problems: Yes	0.3	0.5	3.6	0.1	0.3	0.1	1.9	-0.1	0.2	0.4	-0.4	0.8	0.4
Severe depression (siblings)	0.3	0.3	2.6	-0.1	-0.3	0.0	0.5	-1.6	0.1	0.1	0.3	-0.3	-0.4
Townsend deprivation index at recruitment	0.3	0.4	1.6	0.5	0.5	0.3	-1.0	-0.8	0.4	-0.1	1.3	0.3	-0.2
Current tobacco smoking	0.3	0.6	3.0	0.2	0.6	0.5	0.8	0.3	0.6	0.5	0.4	1.7	0.7
Maternal smoking around birth	0.3	0.5	1.8	-0.8	-0.3	-0.7	-0.3	-1.3	-0.6	-0.6	-0.1	-0.5	-0.7
High blood pressure	0.3	0.9	2.4	-1.0	-1.0	-0.9	-0.4	1.6	-0.7	-1.0	-0.4	-1.1	-0.7
Sitting height	0.3	2.0	6.9	-1.2	-1.1	-1.2	0.1	-0.0	-1.3	-1.3	-2.6	-1.4	-1.9
Past tobacco smoking	0.3	0.6	3.7	0.2	-1.0	0.3	-0.7	-1.9	0.2	0.2	-0.1	0.7	-0.1
Qualifications: None of the above	0.3	0.6	2.3	-0.1	-1.3	-0.4	-0.7	-1.5	-0.3	-0.6	-0.1	0.1	-1.0
Medication: Simvastatin	0.3	0.4	1.4	-0.5	-0.6	-0.5	-0.8	0.5	-0.5	-0.4	-1.2	0.6	-0.1
Illnesses of siblings	0.3	0.4	1.8	0.5	1.1	0.2	-0.4	-0.3	0.1	0.3	1.3	0.3	0.3
Neuroticism score	0.3	0.7	1.9	-0.5	-1.4	-1.0	1.0	-0.1	-0.9	-0.8	-0.1	-0.0	-1.0
Arm fat percentage (right)	0.3	1.0	2.4	-0.2	-1.5	-1.0	-1.1	-0.4	-1.0	-1.1	-1.4	0.3	-1.0
Father’s age at death	0.3	0.5	2.6	0.1	-0.3	0.6	0.5	0.8	0.6	0.3	-1.6	0.3	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.1	-0.6	-0.9	-0.8	0.7	1.0	-0.8	-0.7	-0.3	-0.3	-0.5
Falls in the last year	0.3	0.4	0.9	-0.9	-0.5	-1.0	0.1	0.5	-0.8	-0.9	0.4	0.2	0.3
Impedance of arm (left)	0.3	1.4	5.3	-0.7	-1.2	-0.7	-0.5	-1.6	-0.7	-1.0	2.3	-0.8	-1.1
Arm fat mass (right)	0.3	1.2	5.2	-0.3	-1.2	-1.0	-0.8	-0.2	-1.0	-1.0	-2.3	0.2	-1.0
Hair/balding pattern: Pattern 4	0.3	0.8	3.7	0.3	1.9	0.2	-0.2	-0.1	0.0	0.4	1.5	1.0	0.8
High blood pressure (siblings)	0.3	0.4	2.1	0.2	0.2	0.3	-0.2	1.0	0.4	-0.1	-1.4	-0.2	0.4
Number of full brothers	0.3	0.3	1.8	0.6	-0.6	0.3	1.3	-0.0	0.4	0.1	-0.2	0.0	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	-0.1	1.1	0.3	0.3	-0.6	0.2	0.2	1.3	-1.0	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.6	0.1	-0.1	0.1	0.2	1.2	0.2	0.3	-0.5	1.2	0.4
Eye problems/disorders: None of the above	0.3	0.4	1.4	0.2	0.0	0.5	0.7	-1.2	0.6	0.8	-0.7	0.5	-0.1
Medication for pain relief, constipation, heartburn	0.3	0.4	3.7	0.0	-0.2	0.2	-0.4	-0.3	0.3	-0.2	1.9	-0.5	0.1
Mean time to correctly identify matches	0.3	0.6	2.2	0.3	1.1	0.1	0.4	1.5	0.1	0.3	-1.1	0.8	0.7
Suffer from ‘nerves’	0.3	0.5	3.3	0.1	-0.2	0.1	-0.6	1.8	0.2	0.1	1.0	0.4	0.1
Supplements: Vitamin C	0.3	0.3	1.1	0.5	1.0	0.6	-0.8	-0.3	0.6	0.6	-0.4	0.2	0.1
Arm fat percentage (left)	0.3	1.1	2.8	-0.3	-1.7	-1.0	-1.4	-0.8	-1.0	-1.0	-1.2	0.4	-1.1
Mood swings	0.3	0.5	1.6	-0.1	-1.3	-0.8	-0.2	-0.7	-0.7	-0.7	0.4	-0.2	-0.9
Arm fat mass (left)	0.3	1.1	4.0	-0.3	-1.3	-1.0	-1.0	-0.2	-1.1	-1.0	-2.0	0.0	-1.1
Ever taken oral contraceptive pill	0.3	0.4	2.0	-0.0	0.7	-0.1	0.7	0.6	-0.2	0.3	1.4	0.1	0.3
Medication: Blood pressure	0.3	0.5	1.3	-0.8	-0.3	-0.6	-0.5	1.1	-0.6	-0.4	0.2	-1.1	-0.5
Ever smoked	0.3	0.6	2.9	0.6	1.1	0.4	0.2	1.7	0.5	0.5	0.1	0.4	0.6
Number of operations (self-reported)	0.3	0.4	1.6	-1.3	0.2	-0.8	0.5	0.5	-0.9	-0.6	0.5	0.4	0.1
Reaction Time	0.2	0.3	0.9	0.6	0.9	0.1	-0.1	0.9	0.1	0.4	-0.6	0.5	0.5
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.6	-0.2	-0.5	-0.3	-0.7	0.5	-0.5	-0.6	0.3	-0.8	-0.5
Blood Eosinophil Count	0.2	1.8	8.1	0.8	0.1	-0.1	2.8	-0.5	-0.2	-0.6	-2.0	2.1	-0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.3	-0.4	-0.4	-0.3	-0.1	0.9	-0.3	-0.2	-1.5	0.1	-0.3
Tanning	0.2	2.5	4.9	1.6	1.4	2.1	0.3	-1.2	2.2	1.7	1.2	1.3	1.8
Number of treatments/medications taken	0.2	0.4	2.8	-0.0	-0.1	-0.0	0.8	1.7	0.0	0.2	0.0	0.4	0.5
Diabetes (mother)	0.2	0.2	0.9	0.2	-0.3	-0.3	0.0	-0.1	-0.3	-0.2	0.6	-0.9	-0.9
Pack years adult smoking proportion	0.2	0.3	1.8	-0.1	0.4	0.1	-0.5	-0.4	0.2	-0.1	-0.0	1.4	0.6
Impedance of leg (right)	0.2	0.8	4.7	0.3	0.7	0.3	1.4	0.6	0.4	0.7	2.2	-0.3	0.4
Leg fat-free mass (left)	0.2	1.0	7.7	-0.3	-0.5	-0.7	-0.3	0.5	-0.8	-0.7	-2.8	0.1	-0.7
Taking other prescription medications	0.2	0.3	1.2	-0.2	0.3	-0.0	1.1	0.8	-0.0	-0.0	0.2	0.7	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	0.9	-0.2	-1.0	-0.7	-0.1	0.1	-0.6	-0.5	-0.7	-0.8	-1.0
Medication: Atenolol	0.2	0.3	1.5	0.3	0.0	0.2	0.5	0.9	0.2	0.3	-1.2	0.0	0.4
Body mass index (BMI)	0.2	0.9	5.3	-0.1	-1.0	-0.7	-0.9	0.4	-0.8	-0.6	-2.3	0.4	-0.6
Impedance of leg (left)	0.2	1.2	6.2	0.6	0.9	0.6	1.5	-0.1	0.6	0.9	2.5	0.3	0.8
Leg predicted mass (left)	0.2	1.1	7.6	-0.5	-0.6	-0.8	-0.3	0.4	-0.9	-0.9	-2.8	-0.0	-0.8
Trunk fat mass	0.2	0.7	2.7	0.1	-1.0	-0.7	-0.7	-0.3	-0.7	-0.8	-1.7	0.6	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	-0.2	-0.9	-0.4	-0.4	-0.8	-0.5	-0.5	0.3	0.1	-1.0
Had menopause	0.2	0.3	1.3	-0.6	0.1	-0.3	1.1	0.5	-0.3	-0.1	-0.3	-0.9	0.0
Weight	0.2	1.1	7.7	-0.2	-0.8	-0.7	-0.3	0.4	-0.8	-0.7	-2.8	0.2	-0.7
Impedance of arm (right)	0.2	1.1	4.1	-0.7	-1.1	-0.9	-0.2	-0.8	-0.8	-1.2	2.0	-0.9	-1.1
Trunk fat-free mass	0.2	1.1	8.9	-0.1	-0.0	-0.1	1.0	0.9	-0.2	0.0	-3.0	-0.2	-0.3
Worrier / anxious feelings	0.2	0.4	2.1	0.4	0.7	-0.0	0.8	1.4	-0.0	0.2	-0.0	0.6	0.6
Medication: Cholesterol lowering	0.2	0.4	2.0	-0.4	-0.4	-0.4	0.4	1.4	-0.4	-0.2	-0.5	0.6	0.4
Illnesses of mother	0.2	0.2	0.7	0.3	-0.4	0.4	0.1	-0.8	0.4	0.0	-0.7	0.3	-0.3
Trunk predicted mass	0.2	1.0	8.3	0.0	0.1	-0.1	0.9	0.9	-0.2	0.1	-2.9	-0.2	-0.3
Blood clot in the leg (DVT)	0.2	0.2	0.8	-0.0	-0.4	-0.3	-0.4	0.1	-0.2	-0.6	0.5	-0.3	-0.9
Body fat percentage	0.2	0.6	1.3	-0.0	-1.1	-0.8	-0.8	-0.1	-0.8	-0.8	-1.1	0.7	-0.6
Leg fat percentage (right)	0.2	0.6	3.3	0.0	-0.9	-0.7	0.2	0.9	-0.7	-0.3	-1.8	0.2	-0.5
Migraine (self-reported)	0.2	0.2	0.6	0.0	-0.4	-0.5	0.5	0.7	-0.5	-0.4	-0.2	-0.3	-0.4
Medication: Seretide 50 evohaler	0.2	0.3	1.3	0.5	-0.6	0.4	-0.3	0.3	0.5	0.0	-1.1	-0.2	-0.3
Heart disease (mother)	0.2	0.2	0.7	0.7	0.1	0.1	0.8	0.3	0.2	0.2	-0.3	-0.4	0.7
Whole body fat mass	0.2	0.7	3.6	0.0	-1.0	-0.8	-0.6	-0.0	-0.8	-0.7	-1.9	0.6	-0.7
Leg fat mass (right)	0.2	0.9	5.3	-0.2	-0.9	-0.8	-0.0	0.8	-0.9	-0.6	-2.3	0.1	-0.7
Pulse rate, automated reading	0.2	0.7	2.1	-1.2	-0.5	-0.8	-0.4	0.2	-0.8	-0.9	-0.1	-1.1	-1.5
Alcohol intake frequency.	0.2	0.4	1.1	0.6	-1.0	0.3	-0.3	-0.7	0.2	0.1	-1.0	0.1	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.8	-0.6	-0.5	-0.5	-0.1	0.9	-0.4	-0.3	0.4	-0.9	-0.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.9	-0.2	-0.5	0.1	0.6	-0.9	0.1	0.5	-0.7	-0.5	-0.4
Knee pain experienced in last month	0.2	0.3	1.4	0.3	-0.6	-0.2	0.6	1.2	-0.0	-0.1	-0.6	-0.5	0.1
Whole body fat-free mass	0.2	1.0	8.9	-0.2	-0.2	-0.4	0.5	0.7	-0.5	-0.3	-3.0	0.0	-0.4
Diabetes diagnosed by doctor	0.2	0.3	1.0	-0.5	-0.4	-0.4	-0.3	1.0	-0.4	-0.7	-0.0	0.2	-0.6
Mineral and other dietary supplements	0.2	0.3	1.6	0.1	0.2	-0.1	0.7	-0.8	-0.2	0.1	1.2	-0.2	-0.1
Osteoporosis (self-reported)	0.2	0.3	0.8	-0.3	-0.8	-0.3	-0.2	-0.9	-0.3	-0.5	0.1	0.4	-0.6
Whole body water mass	0.2	0.9	8.6	-0.0	-0.1	-0.2	0.5	0.7	-0.3	-0.1	-2.9	0.1	-0.3
Leg predicted mass (right)	0.2	0.8	6.4	-0.3	-0.4	-0.6	-0.3	0.1	-0.7	-0.7	-2.5	0.3	-0.5
Medication: Bendroflumethiazide	0.2	0.2	1.4	0.2	0.3	0.1	-0.5	1.2	0.2	-0.0	0.1	-0.4	0.6
Medication: Atorvastatin	0.2	0.2	1.0	0.2	0.5	0.3	0.1	1.0	0.3	0.2	-0.2	-0.3	0.7
Basal metabolic rate	0.2	1.0	8.5	-0.2	-0.3	-0.5	0.3	0.6	-0.6	-0.4	-2.9	0.0	-0.5
Arm fat-free mass (left)	0.2	0.8	6.8	0.4	0.4	0.1	0.7	0.8	0.1	0.3	-2.6	0.3	0.1
Average weekly beer plus cider intake	0.2	0.3	0.6	-0.3	-0.6	-0.4	-0.7	-0.8	-0.3	-0.7	0.7	-0.4	-0.3
Ever depressed for a whole week	0.2	0.3	1.5	-0.2	1.0	-0.2	-0.4	0.1	-0.2	-0.1	1.2	-0.0	0.4
Commuting to job workplace: Cycle	0.2	0.3	1.2	0.1	0.5	-0.2	0.8	0.1	-0.1	0.1	1.1	0.5	0.3
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.8	0.6	0.7	0.6	0.2	-1.3	0.5	0.6	0.5	0.6	0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.8	0.0	-0.3	-0.2	-0.6	-0.0	-0.2	-0.5	0.9	-0.3	-0.7
Heart disease (siblings)	0.2	0.2	0.9	0.3	-0.1	0.2	1.0	-0.3	0.2	0.2	-0.7	0.5	0.4
Impedance of whole body	0.2	0.9	7.5	-0.1	-0.1	-0.2	0.4	-1.0	-0.1	-0.2	2.7	-0.2	-0.2
Leg fat mass (left)	0.2	0.8	4.7	0.0	-0.8	-0.7	0.0	0.6	-0.8	-0.5	-2.2	0.4	-0.5
Arm predicted mass (left)	0.2	0.8	7.5	0.1	0.0	-0.2	0.4	0.7	-0.3	-0.0	-2.7	-0.0	-0.3
Worry (Nagel 2018)	0.1	0.3	1.6	0.3	-0.2	-0.0	1.3	0.9	0.1	0.0	0.5	0.2	0.1
Ovarian Cancer	0.1	0.1	0.8	-0.2	0.1	-0.3	0.9	-0.3	-0.3	0.0	0.3	-0.2	0.0
Age at First Birth	0.1	0.1	0.6	-0.0	0.5	-0.0	0.3	0.3	-0.0	-0.1	0.7	0.1	0.4
Waist Hip Ratio (WHR)	0.1	0.5	2.3	0.1	1.0	-0.1	-0.7	-0.4	-0.2	-0.2	1.5	0.9	0.2
Systolic Blood Pressure	0.1	0.5	1.4	-0.1	0.7	0.2	1.2	0.7	0.2	0.6	1.1	0.3	0.8
Lung FEV1/FVC ratio	0.1	0.3	2.3	0.3	0.2	0.1	0.1	0.3	0.1	0.5	-0.1	1.5	0.5
Lung FVC	0.1	0.5	2.1	0.3	0.3	0.2	-1.0	-0.9	0.2	0.6	1.4	0.2	0.6
Hand grip strength (left)	0.1	0.2	0.4	-0.4	0.1	-0.5	0.2	0.6	-0.6	-0.2	-0.6	-0.6	-0.4
Trunk fat percentage	0.1	0.6	1.0	0.1	-1.0	-0.7	-0.9	-0.7	-0.6	-0.8	-0.9	0.9	-0.6
Hand grip strength (right)	0.1	0.1	0.4	-0.3	0.1	-0.5	-0.5	-0.1	-0.7	-0.2	-0.0	-0.5	-0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.2	0.7	-0.1	0.1	-0.2	-0.2	0.8	-0.2	-0.2	-0.7	-0.4	0.1
Waist circumference	0.1	0.4	3.0	0.4	-0.1	-0.1	-0.5	0.2	-0.2	-0.1	-1.7	0.5	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.6	0.8	-0.1	0.1	0.1	0.4	0.2	0.4	-0.1	-0.5	0.0
Hip circumference	0.1	0.6	4.7	0.7	-0.1	0.3	0.4	0.4	0.3	0.4	-2.2	0.4	0.0
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.1	-0.2	-0.8	-1.0	-0.3	0.3	-1.1	-0.5	-0.5	-0.2	-0.6
Pulse rate	0.1	0.2	0.9	-0.9	0.5	-0.4	-0.1	0.1	-0.4	-0.1	0.2	-0.3	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.5	-0.1	-0.4	-0.7	0.3	0.2	-0.7	-0.2	0.6	0.5	-0.0
Tense / ‘highly strung’	0.1	0.2	1.6	-0.3	-0.4	-0.1	0.3	1.2	-0.1	-0.0	-0.2	0.3	-0.0
Peak expiratory flow (PEF)	0.1	0.2	0.8	0.5	0.6	-0.3	-0.1	0.9	-0.5	0.3	0.6	-0.1	0.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	0.3	-0.3	-0.2	-0.5	-0.8	-0.3	-0.1	-0.5	-0.3	-0.6
Headache pain in last month	0.1	0.3	1.0	0.2	0.7	0.1	1.0	-0.2	0.0	0.4	-0.1	0.7	0.5
Arm fat-free mass (right)	0.1	0.6	5.5	0.2	0.4	0.0	0.6	0.5	-0.1	0.2	-2.3	0.3	0.0
Number of children fathered	0.1	0.1	0.6	-0.2	-0.6	-0.1	-0.4	0.1	-0.1	-0.3	-0.2	-0.7	-0.4
Emphysema/chronic bronchitis	0.1	0.2	1.0	0.2	-0.2	0.2	-0.6	-1.0	0.2	-0.2	0.4	-0.1	-0.2
Medication: Omeprazole	0.1	0.1	0.3	-0.1	0.5	-0.1	0.1	0.1	-0.1	0.0	0.0	0.5	0.3
Arm predicted mass (right)	0.1	0.7	5.2	0.4	0.6	0.2	0.9	0.3	0.1	0.5	-2.3	0.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.2	-0.0	0.2	-0.5	0.4	1.1	-0.5	-0.3	-0.5	0.2	-0.2
Leg fat-free mass (right)	0.1	0.8	6.0	-0.3	-0.4	-0.6	-0.3	0.1	-0.7	-0.7	-2.5	0.2	-0.5
Average weekly champagne plus white wine intake	0.1	0.2	1.2	-0.6	0.3	-0.1	-0.3	-0.0	-0.1	-0.1	-0.1	1.1	0.1
Wears glasses or contact lenses	0.1	0.1	0.2	0.1	-0.3	-0.0	-0.4	0.2	0.1	-0.4	-0.2	0.3	0.1
Illnesses of father: High blood pressure	0.1	0.2	0.4	0.5	-0.2	0.6	-0.3	0.4	0.7	0.5	-0.1	0.3	0.1
Leg fat percentage (left)	0.1	0.5	2.9	0.3	-0.7	-0.4	0.1	0.5	-0.5	-0.1	-1.7	0.7	-0.2
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.5	-0.2	0.4	0.0	0.7	0.0	-0.0	0.1	0.5	0.7	0.5
Pack years of smoking	0.1	0.2	1.2	-0.3	0.4	0.1	-0.3	-0.2	0.2	-0.1	-0.3	1.1	0.5
Heel T-Score	0.0	0.3	1.0	0.7	0.6	0.1	-1.0	-1.0	0.2	0.2	0.4	-0.1	0.1
Height	0.0	0.6	2.6	-0.6	0.2	0.1	1.1	-1.6	0.0	-0.3	-1.4	0.1	0.2
Hair Pigment	0.0	0.2	1.8	0.2	-0.5	0.1	0.1	-1.3	-0.0	0.5	-0.2	-0.1	-0.0
Forced vital capacity (FVC)	0.0	0.1	0.7	0.2	-0.2	-0.3	-0.1	0.4	-0.3	0.0	-0.8	0.1	-0.2
Ever unenthusiastic/disinterested for a whole week	0.0	0.1	0.2	0.2	0.4	0.0	-0.1	0.1	0.0	0.2	-0.2	-0.4	0.3
Diabetes (self-reported)	0.0	0.1	0.5	-0.1	-0.1	0.1	0.1	0.7	0.1	0.2	0.2	0.3	-0.3
Depression (self-reported)	0.0	0.1	0.2	-0.2	0.0	0.1	0.1	-0.5	0.1	0.1	0.3	-0.0	-0.3
Standing height	0.0	0.4	2.5	-0.2	0.3	-0.1	1.6	-0.1	-0.2	-0.3	-1.0	-0.3	-0.3
Forced vital capacity (FVC), Best measure	0.0	0.1	0.3	-0.2	-0.3	-0.5	0.1	0.0	-0.5	-0.3	0.3	0.3	-0.0
Diastolic blood pressure, automated reading	0.0	0.1	0.4	-0.0	-0.5	0.4	-0.4	0.1	0.4	0.5	-0.7	-0.2	-0.2

Hub : Genes

IL7

Models

Trait associations