Best TWAS P=7.17e-18 · Best GWAS P=3.3e-21 conditioned to 6.92e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | PVT1 | 0.19 | 0.12 | lasso | 2 | 0.09 | 3.1e-07 | 8.5 | 8.6 | 7.2e-18 | 0.69 | 0.02 | 0.98 | TRUE |
| 2 | GTEx | Whole Blood | PVT1 | 0.12 | 0.07 | lasso | 4 | 0.06 | 6.3e-06 | 8.5 | 8.4 | 5.4e-17 | 0.67 | 0.04 | 0.96 | FALSE |
| 3 | METSIM | Adipose | FAM84B | 0.17 | 0.12 | lasso | 5 | 0.12 | 2.8e-17 | 5.9 | -5.9 | 3.5e-09 | 0.01 | 0.00 | 1.00 | TRUE |
| 4 | YFS | Blood | FAM84B | 0.29 | 0.20 | lasso | 10 | 0.21 | 2.5e-67 | 5.9 | -5.7 | 1.3e-08 | 0.02 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PVT1 | 0.06 | 0.04 | lasso | 4 | 0.04 | 4.2e-05 | 8.5 | 8.4 | 5.7e-17 | 0.64 | 0.09 | 0.82 | FALSE |