TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood White Count
:
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chr8:126,867,367-129,812,343
Best TWAS P=7.17e-18 · Best GWAS P=3.3e-21 conditioned to 6.92e-07
127M
127.5M
128M
128.5M
129M
129.5M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Lung
PVT1
0.19
0.12
lasso
2
0.09
3.1e-07
8.5
8.6
7.2e-18
0.69
0.02
0.98
TRUE
3
METSIM
Adipose
FAM84B
0.17
0.12
lasso
5
0.12
2.8e-17
5.9
-5.9
3.5e-09
0.01
0.00
1.00
TRUE
2
GTEx
Whole Blood
PVT1
0.12
0.07
lasso
4
0.06
6.3e-06
8.5
8.4
5.4e-17
0.67
0.04
0.96
FALSE
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
PVT1
0.06
0.04
lasso
4
0.04
4.2e-05
8.5
8.4
5.7e-17
0.64
0.09
0.82
FALSE
4
YFS
Blood
FAM84B
0.29
0.20
lasso
10
0.21
2.5e-67
5.9
-5.7
1.3e-08
0.02
0.00
1.00
FALSE