[Hub]/) : Traits : Blood White Count : ← →

chr8:141,436,052-143,138,709

Best TWAS P=5.95e-40 · Best GWAS P=5.36e-40 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Whole Blood	SLC45A4	0.20	0.17	lasso	2	0.16	7.6e-15	-13.2	13.2	6.0e-40	-1.00	0.00	1.00	TRUE
4	GTEx	Colon Sigmoid	SLC45A4	0.22	0.16	lasso	9	0.14	8.3e-06	7.8	8.1	6.4e-16	-0.14	0.60	0.02	TRUE
9	NTR	Blood	SLC45A4	0.05	0.04	bslmm	459	0.05	1.1e-14	-13.2	12.2	1.9e-34	-0.97	0.00	1.00	FALSE
6	GTEx	Spleen	SLC45A4	0.59	0.12	lasso	8	0.30	1.5e-08	-13.2	9.5	2.2e-21	-0.71	0.00	0.97	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	DENND3	0.10	0.05	bslmm	451	0.05	2.5e-07	7.1	8.0	1.4e-15	-0.20	0.98	0.00	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC45A4	0.04	0.05	lasso	1	0.03	1.3e-04	7.8	7.8	7.9e-15	-0.16	0.01	0.99	FALSE
8	NTR	Blood	DENND3	0.03	0.01	lasso	2	0.01	7.9e-05	-6.2	7.7	1.2e-14	-0.16	0.60	0.06	FALSE
5	GTEx	Esophagus Mucosa	SLC45A4	0.36	0.13	lasso	10	0.30	4.7e-20	-4.4	-7.3	2.1e-13	0.54	1.00	0.00	FALSE
11	YFS	Blood	DENND3	0.22	0.25	lasso	10	0.26	6.3e-85	-5.5	7.3	2.4e-13	-0.02	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	GPR20	0.05	0.00	blup	30	0.02	2.1e-02	-10.0	-6.8	1.0e-11	0.43	0.00	0.80	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DENND3	0.09	0.08	lasso	4	0.07	2.6e-09	-6.3	6.7	2.2e-11	0.02	1.00	0.00	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PTP4A3	0.22	0.03	enet	15	0.06	9.8e-04	2.2	-6.4	1.8e-10	0.51	0.02	0.04	FALSE
12	YFS	Blood	PTP4A3	0.14	0.05	bslmm	461	0.10	1.9e-32	3.2	-6.4	2.0e-10	0.33	1.00	0.00	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	DENND3	0.07	0.01	blup	98	0.05	3.3e-06	-5.0	6.2	5.8e-10	-0.04	0.09	0.84	FALSE
15	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	DENND3	0.16	0.09	lasso	4	0.10	1.7e-05	-6.1	5.7	1.6e-08	0.04	0.15	0.10	FALSE
2	GTEx	Breast Mammary Tissue	SLC45A4	0.19	0.01	lasso	4	0.03	9.1e-03	7.8	5.4	6.4e-08	-0.12	0.31	0.11	FALSE
3	GTEx	Breast Mammary Tissue (Male)	SLC45A4	0.29	0.06	lasso	6	0.02	9.3e-02	3.5	5.2	2.2e-07	-0.15	0.05	0.11	FALSE