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chr9:85,657,836-87,315,117

Best TWAS P=9.22e-26 · Best GWAS P=2.45e-26 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RMI1	0.07	0.06	lasso	3	0.06	1.4e-07	-10.2	10.5	9.2e-26	-0.99	0.01	0.99	TRUE
2	GTEx	Adipose Subcutaneous	RMI1	0.11	0.03	lasso	3	0.04	3.8e-04	6.1	6.0	2.5e-09	-0.53	0.13	0.80	FALSE
3	GTEx	Artery Aorta	GKAP1	0.15	0.02	enet	24	0.03	6.0e-03	-6.4	5.3	1.0e-07	-0.42	0.12	0.48	FALSE
4	GTEx	Esophagus Mucosa	GKAP1	0.09	0.06	lasso	2	0.02	2.9e-02	-6.4	6.4	1.4e-10	-0.66	0.34	0.40	FALSE
5	GTEx	Testis	RMI1	0.12	0.11	enet	15	0.14	1.3e-06	6.1	8.7	3.3e-18	-0.83	0.03	0.96	FALSE
6	METSIM	Adipose	RMI1	0.04	0.02	lasso	7	0.01	4.9e-03	6.3	5.9	3.9e-09	-0.54	0.71	0.04	FALSE
7	YFS	Blood	GKAP1	0.02	0.01	blup	614	0.01	3.2e-04	-9.9	6.5	6.0e-11	-0.70	0.02	0.98	FALSE
8	YFS	Blood	KIF27	0.05	0.01	bslmm	609	0.02	1.3e-06	3.5	5.5	4.0e-08	-0.45	0.88	0.07	FALSE
9	YFS	Blood	RMI1	0.07	0.09	bslmm	528	0.09	1.5e-27	-10.2	-10.4	2.4e-25	0.96	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UBQLN1	0.03	0.02	lasso	2	0.01	2.3e-02	-6.1	6.0	1.7e-09	-0.53	0.07	0.12	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	RMI1	0.02	0.02	blup	31	0.01	8.8e-04	-10.6	10.0	1.2e-23	-0.94	0.01	0.94	FALSE
12	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RMI1	0.05	0.04	lasso	2	0.00	1.8e-01	6.1	6.1	8.9e-10	-0.58	0.02	0.16	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	RMI1	0.40	0.03	lasso	2	0.06	1.9e-04	6.1	5.9	3.0e-09	-0.54	0.20	0.10	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RMI1	0.03	0.03	lasso	4	0.04	4.1e-05	-10.5	9.9	4.8e-23	-0.93	0.01	0.96	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	RMI1	0.03	0.03	blup	31	0.01	1.2e-02	-10.6	10.5	1.0e-25	-0.98	0.01	0.97	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	C9orf64	0.07	0.03	enet	14	0.03	3.3e-04	6.3	-5.9	3.0e-09	0.61	0.02	0.63	FALSE
17	The Cancer Genome Atlas	Rectum Adenocarcinoma	UBQLN1	0.22	0.02	lasso	3	0.09	3.5e-03	-6.1	5.2	1.5e-07	-0.41	0.03	0.19	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	RMI1	0.05	0.06	enet	5	0.06	2.2e-05	6.3	7.9	2.4e-15	-0.72	0.09	0.55	FALSE
19	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C9orf64	0.17	0.05	enet	8	0.09	4.5e-04	6.2	-7.3	3.9e-13	0.76	0.02	0.74	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	GKAP1	0.05	0.06	lasso	3	0.06	1.2e-06	-6.7	6.7	2.6e-11	-0.71	0.75	0.23	FALSE