TWAS
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Models
Genes
Traits
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Traits
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Blood White Count
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chr9:97,520,168-99,734,369
Best TWAS P=7.03e-10 · Best GWAS P=5.63e-09 conditioned to 0.0427
97.5M
98M
98.5M
99M
99.5M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Nerve Tibial
HSD17B3
0.14
0.00
enet
20
0.00
2.4e-01
-4.8
-6.2
7.0e-10
0.04
0.05
0.57
TRUE
1
GTEx
Liver
PTCH1
0.25
0.06
enet
11
0.03
4.9e-02
-5.8
-5.2
1.6e-07
0.91
0.01
0.94
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
CDC14B
0.05
0.07
blup
42
0.08
4.8e-08
-4.9
5.1
3.1e-07
-0.02
0.03
0.97
FALSE