Best TWAS P=7.03e-10 · Best GWAS P=5.63e-09 conditioned to 0.0427
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | PTCH1 | 0.25 | 0.06 | enet | 11 | 0.03 | 4.9e-02 | -5.8 | -5.2 | 1.6e-07 | 0.91 | 0.01 | 0.94 | TRUE |
| 2 | GTEx | Nerve Tibial | HSD17B3 | 0.14 | 0.00 | enet | 20 | 0.00 | 2.4e-01 | -4.8 | -6.2 | 7.0e-10 | 0.04 | 0.05 | 0.57 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CDC14B | 0.05 | 0.07 | blup | 42 | 0.08 | 4.8e-08 | -4.9 | 5.1 | 3.1e-07 | -0.02 | 0.03 | 0.97 | FALSE |