Best TWAS P=2.36e-44 · Best GWAS P=2.98e-38 conditioned to 0.582
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | LPAR1 | 0.10 | 0.00 | enet | 23 | 0.00 | 2.3e-01 | 12.9 | 11.0 | 5.4e-28 | 0.71 | 0.01 | 0.97 | FALSE |
| 2 | METSIM | Adipose | LPAR1 | 0.10 | 0.02 | enet | 26 | 0.06 | 7.4e-09 | 12.3 | 13.3 | 3.8e-40 | 0.64 | 0.01 | 0.99 | TRUE |
| 3 | NTR | Blood | LPAR1 | 0.19 | 0.07 | lasso | 10 | 0.14 | 2.1e-43 | 12.9 | 14.0 | 2.4e-44 | 0.75 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ZNF483 | 0.11 | 0.00 | blup | 60 | 0.03 | 1.3e-02 | -2.5 | -5.3 | 8.8e-08 | -0.21 | 0.01 | 0.50 | TRUE |