[Hub]/) : Traits : Blood White Count : ← →

chr11:119,496,472-121,057,430

Best TWAS P=5.99e-13 · Best GWAS P=4.24e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARHGEF12 0.05 0.04 lasso 2 0.04 5.9e-06 -4.6 -5.8 7.1e-09 -0.86 0.04 0.96 FALSE
2 CommonMind Brain Pre-frontal Cortex TMEM136 0.04 0.03 lasso 2 0.02 2.4e-03 7.2 6.5 7.9e-11 0.98 0.02 0.96 FALSE
3 GTEx Artery Tibial TMEM136 0.09 0.02 lasso 2 0.01 2.2e-02 7.2 6.9 3.8e-12 0.99 0.02 0.97 FALSE
4 GTEx Nerve Tibial TMEM136 0.23 0.19 lasso 6 0.23 1.4e-16 7.2 5.6 2.5e-08 0.91 0.02 0.98 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic TMEM136 0.25 0.04 enet 19 0.09 1.3e-05 7.1 5.6 1.7e-08 0.74 0.03 0.95 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma ARHGEF12 0.01 0.02 lasso 1 0.01 6.6e-04 7.1 -7.1 1.1e-12 -0.93 0.02 0.88 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM136 0.05 0.06 enet 7 0.06 1.8e-07 7.1 7.2 6.0e-13 0.99 0.01 0.99 TRUE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors TMEM136 0.14 0.00 blup 45 0.10 2.2e-04 7.2 5.5 3.9e-08 0.71 0.01 0.68 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma TMEM136 0.03 0.03 enet 8 0.02 3.5e-03 7.1 6.6 4.8e-11 0.91 0.01 0.96 FALSE