TWAS hub - TMEM136

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0420	0.0180	4.8e-03	0.030	0.015	0.017	0.016	0.018	1.1e-04	5.2e-03	3.3e-03	0.0043	2.4e-03
2	GTEx	Adipose Subcutaneous	0.0900	0.0300	1.7e-04	0.037	NA	0.069	NA	0.055	5.2e-04	NA	2.8e-06	NA	2.5e-05
3	GTEx	Artery Tibial	0.0920	0.0388	1.8e-03	0.017	NA	-0.002	NA	0.015	1.5e-02	NA	5.4e-01	NA	2.2e-02
4	GTEx	Colon Sigmoid	0.1770	0.0640	1.6e-03	0.016	NA	0.019	NA	0.025	8.8e-02	NA	7.1e-02	NA	4.4e-02
5	GTEx	Lung	0.0987	0.0371	1.7e-03	0.035	NA	0.035	NA	0.023	1.0e-03	NA	9.8e-04	NA	6.7e-03
6	GTEx	Nerve Tibial	0.2330	0.0504	1.0e-11	0.186	NA	0.214	NA	0.234	3.2e-13	NA	3.8e-15	NA	1.4e-16
7	GTEx	Skin Not Sun Exposed Suprapubic	0.2480	0.0620	6.9e-06	0.045	NA	0.089	NA	0.073	1.7e-03	NA	1.3e-05	NA	8.1e-05
8	GTEx	Thyroid	0.0930	0.0390	5.8e-03	-0.003	NA	-0.003	NA	-0.004	7.0e-01	NA	7.3e-01	NA	1.0e+00
9	TCGA	Colon Adenocarcinoma	0.0480	0.0270	8.7e-03	0.011	0.030	0.022	NA	0.017	7.2e-02	7.2e-03	2.0e-02	NA	3.4e-02
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0483	0.0207	1.6e-05	0.032	0.045	0.041	NA	0.033	1.4e-04	7.2e-06	1.7e-05	NA	1.1e-04
11	TCGA	Brain Lower Grade Glioma	0.0482	0.0196	2.1e-06	0.061	0.052	0.061	NA	0.060	1.9e-07	1.2e-06	1.8e-07	NA	2.4e-07
12	TCGA	Pheochromocytoma and Paraganglioma	0.1840	0.1010	6.2e-03	0.016	0.021	0.011	NA	0.007	7.5e-02	4.9e-02	1.1e-01	NA	1.7e-01
13	TCGA	Testicular Germ Cell Tumors	0.1420	0.0710	3.2e-03	0.003	0.100	0.057	NA	0.048	2.5e-01	2.2e-04	4.6e-03	NA	8.8e-03
14	TCGA	Thyroid Carcinoma	0.0330	0.0170	2.1e-03	0.031	0.021	0.021	NA	0.013	5.4e-04	3.7e-03	3.5e-03	NA	1.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Breastfed as a baby	14.1	17.5	28.7	-4.1	-3.0	-4.6	-4.3	-3.1	-4.7	-2.7	-3.0	-5.4	-5.0	-4.3	-2.2	-5.2	-5.2
Eye problems/disorders: Glaucoma	12.0	14.2	24.1	4.5	4.5	4.3	2.9	2.3	3.9	2.0	2.4	4.6	3.7	4.4	0.9	4.9	4.7
Glaucoma (self-reported)	10.5	12.3	21.3	4.3	4.2	4.1	3.1	2.1	4.0	1.8	1.6	3.9	3.6	4.2	0.7	4.0	4.6
Medication: Ramipril	7.7	9.9	18.4	3.8	3.5	4.3	2.6	0.7	3.5	2.0	0.8	3.3	3.0	4.0	2.6	3.0	4.1
Angina	7.6	10.0	15.4	3.1	2.3	3.6	3.9	3.1	3.9	2.9	2.0	3.2	3.0	3.5	2.4	2.6	3.9
Alcohol usually taken with meals	6.9	11.2	19.4	-3.6	-3.8	-4.4	-3.8	-3.7	-4.1	-1.6	-2.3	-2.2	-2.8	-3.8	-3.4	-3.0	-3.2
Angina (self-reported)	6.6	8.7	13.8	2.9	2.2	3.4	3.7	2.7	3.7	2.5	2.0	2.9	2.9	3.3	2.3	2.4	3.6
Medication: Blood pressure	5.7	10.0	15.7	3.9	3.9	4.0	3.5	2.9	3.9	2.3	0.1	2.2	2.2	3.9	3.0	2.2	3.8
Number of treatments/medications taken	5.0	9.0	15.3	3.4	3.2	3.9	3.1	2.0	3.3	2.3	0.7	3.2	2.9	3.9	2.0	2.9	3.7
Heart attack/myocardial infarction (self-reported)	4.5	5.8	12.0	2.9	3.0	3.5	2.9	1.3	3.1	1.7	-0.2	1.7	1.8	3.0	2.5	1.1	2.8
Medication for pain relief, constipation, heartburn	4.4	7.6	13.9	-3.1	-2.6	-3.7	-3.0	-2.2	-3.6	-2.4	-1.6	-2.4	-3.0	-3.6	-1.0	-1.2	-3.2
Ulcerative Colitis	4.3	6.3	12.2	-2.3	-1.9	-2.4	-2.7	-2.1	-2.8	-1.5	-0.8	-3.4	-3.3	-2.4	-1.1	-3.5	-3.1
Smoking Status	4.2	10.1	17.2	3.7	2.3	4.0	3.7	3.8	4.2	3.3	0.6	2.0	2.8	3.8	2.6	2.4	3.2
Heart attack	4.2	5.3	11.3	2.7	3.0	3.4	2.7	1.1	2.9	1.4	-0.2	1.7	1.7	2.8	2.3	1.1	2.7
Overall health rating	4.2	8.9	14.8	2.8	0.5	3.8	3.3	2.9	3.6	1.5	-0.2	3.8	3.8	3.5	1.6	3.2	3.8
Medication for cholesterol, blood pressure or diabetes	4.1	6.7	11.9	-2.9	-2.8	-3.2	-2.7	-1.9	-3.1	-1.2	0.8	-2.9	-2.4	-3.1	-1.6	-2.7	-3.4
Vascular/heart problems diagnosed by doctor	4.1	11.1	20.7	-3.9	-3.9	-4.6	-3.4	-2.4	-3.8	-2.3	-0.2	-3.0	-2.6	-4.2	-2.7	-3.0	-4.2
Blood Platelet Count	3.9	45.4	89.5	8.8	6.7	9.5	5.0	2.7	7.0	6.5	2.6	6.1	4.5	9.4	5.7	6.7	8.3
Serious illness, injury or assault to yourself	3.9	4.7	8.4	1.9	1.0	2.2	2.9	2.2	2.7	2.2	1.8	2.1	2.6	2.4	1.3	1.9	2.3
Medication for cholesterol	3.8	5.8	14.7	-3.2	-1.8	-3.8	-2.4	-2.6	-3.0	-1.6	-1.1	-1.6	-1.5	-3.2	-1.6	-1.3	-2.9
Blood White Count	3.7	27.3	51.8	6.5	4.2	6.9	4.3	2.3	5.6	5.6	2.6	4.6	3.2	7.2	4.9	5.5	6.6
Intelligence (Savage-Jansen 2018)	3.6	11.0	19.5	-3.8	-2.9	-4.1	-2.6	-1.6	-3.7	-3.4	-1.6	-4.4	-3.5	-3.7	-0.4	-3.6	-4.4
Breast Cancer	3.6	8.7	13.8	-3.6	-3.2	-3.3	-3.1	-0.4	-3.3	-3.2	-1.1	-3.0	-3.0	-3.7	-2.4	-2.6	-3.4
Medication: Cholesterol lowering	3.5	5.4	11.0	2.5	2.2	2.9	2.0	1.2	2.7	0.7	-0.3	3.3	2.6	2.8	-0.0	2.5	3.3
Health satisfaction	3.3	4.3	8.3	2.6	1.6	2.6	2.0	1.4	2.6	1.9	-0.9	1.8	1.7	2.8	1.0	2.0	2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.3	3.8	5.7	2.3	1.9	2.4	2.2	1.1	2.4	0.7	1.2	1.7	2.0	2.3	2.2	2.0	2.2
Medication: Aspirin	3.2	4.2	8.0	1.8	2.0	2.2	2.3	1.5	2.5	1.6	0.2	2.8	2.7	2.1	-0.4	2.1	2.6
Medication: Ibuprofen (e.g. Nurofen)	3.0	3.8	11.2	1.9	1.8	1.9	2.3	1.8	2.3	1.8	3.3	1.0	1.4	2.2	1.9	0.7	1.7
Medication: Lansoprazole	3.0	3.4	6.4	2.1	0.3	2.5	1.8	1.2	1.9	1.9	0.9	1.5	1.8	2.2	2.4	2.1	2.0
Medication: Aspirin	3.0	3.9	6.7	1.9	2.0	2.3	2.0	1.2	2.4	1.8	0.2	2.6	2.6	2.0	-0.3	1.7	2.5
Reaction Time	2.9	5.6	8.9	-2.3	-1.8	-2.1	-3.0	-2.5	-2.9	-1.7	-2.2	-2.1	-2.5	-2.6	-2.7	-1.5	-2.7
Ulcerative Colitis (UC)	2.8	5.2	8.6	-2.3	-2.1	-2.3	-2.5	-2.0	-2.7	-1.2	-1.1	-2.9	-2.8	-2.2	-0.6	-2.9	-2.7
Severe depression (siblings)	2.8	3.1	8.3	2.6	1.1	2.9	1.5	0.8	2.0	2.1	1.2	0.7	0.6	2.5	1.8	1.5	1.6
High blood pressure	2.8	7.9	14.2	3.3	3.4	3.8	2.9	1.9	3.2	2.0	0.3	2.3	2.0	3.5	2.7	2.5	3.4
Allergy	2.8	6.4	11.3	3.4	3.1	3.3	2.5	2.2	3.1	1.4	2.8	1.1	1.4	3.3	2.1	1.1	2.5
Noisy workplace	2.7	3.4	6.0	1.7	2.0	2.1	1.9	1.7	2.0	2.5	0.7	1.6	1.2	1.9	1.4	2.2	2.1
Hypothyroidism/myxoedema (self-reported)	2.6	5.0	7.7	2.0	1.7	2.2	2.6	2.4	2.3	2.2	0.6	2.7	2.3	2.3	1.5	2.6	2.8
Mean time to correctly identify matches	2.6	5.0	7.4	-2.3	-1.9	-1.9	-2.6	-2.3	-2.7	-0.6	-2.3	-2.4	-2.5	-2.5	-2.0	-1.9	-2.6
Ever taken oral contraceptive pill	2.6	2.9	6.1	1.5	2.0	1.5	2.5	0.9	2.2	0.0	1.3	1.5	1.7	1.7	1.8	1.9	2.0
Depression (Nagel 2018)	2.5	3.8	7.7	2.8	2.0	2.8	1.7	1.8	2.3	2.6	1.6	0.8	1.3	2.4	0.7	0.2	2.0
Supplements: Vitamin C	2.5	3.0	5.9	1.8	1.3	1.5	2.2	2.3	1.7	1.6	2.4	1.7	1.8	1.4	0.9	1.3	1.6
Hypertension (Self-reported)	2.5	7.1	13.5	3.1	3.1	3.7	2.7	1.9	3.1	1.8	0.1	2.2	1.8	3.4	2.5	2.4	3.2
Pack years adult smoking proportion	2.4	3.6	6.3	1.7	1.8	2.1	1.9	1.6	1.9	1.7	1.0	2.1	1.7	2.0	1.9	2.5	2.3
Hayfever, allergic rhinitis or eczema	2.4	5.2	9.7	-2.7	-2.7	-2.7	-2.8	-2.3	-3.1	-1.3	-1.8	-1.2	-1.8	-2.8	-1.7	-1.6	-2.3
Financial difficulties in last 2 years	2.4	3.2	9.7	1.2	-1.0	1.1	2.6	3.1	2.0	0.8	0.6	2.1	2.6	1.1	1.4	2.0	1.4
Medication: Simvastatin	2.4	3.6	6.0	1.7	1.2	2.1	2.3	1.4	2.4	1.0	1.0	2.4	2.1	2.1	1.4	2.0	2.4
Fluid intelligence score	2.4	4.9	7.7	-2.3	-1.4	-2.6	-2.2	-1.7	-2.5	-1.9	-2.4	-2.4	-2.1	-2.5	-1.7	-2.1	-2.8
Medication: Amlodipine	2.4	3.4	7.7	2.2	2.2	2.8	1.8	0.8	2.1	1.0	1.1	0.3	0.4	2.7	2.5	0.7	2.1
Had major operations	2.4	2.8	11.0	-1.0	-1.2	-1.0	-1.9	-1.0	-1.8	-0.9	-3.3	-1.9	-2.2	-0.9	-0.8	-1.9	-1.6
Hearing aid user	2.4	2.7	4.9	1.8	0.7	1.9	1.6	1.4	1.9	1.7	-0.7	1.9	2.2	1.8	-0.2	1.6	2.0
Hypothyroidism (self reported)	2.3	5.3	7.7	2.2	2.1	2.4	2.6	2.5	2.4	2.6	-0.0	2.3	2.1	2.5	1.9	2.4	2.8
Hayfever/allergic rhinitis (self-reported)	2.3	3.1	5.5	-1.9	-1.4	-1.9	-2.3	-2.1	-2.4	-0.3	-1.0	-1.9	-2.2	-1.9	-0.3	-1.3	-2.1
Bilateral oophorectomy (both ovaries removed)	2.2	2.5	4.7	1.6	0.9	1.6	2.2	1.9	2.0	0.8	1.8	1.5	1.8	1.5	0.8	1.2	1.7
Medication: Levothyroxine sodium	2.2	3.8	6.6	1.6	1.9	1.9	2.6	2.1	2.0	1.7	0.7	2.2	2.0	1.8	2.1	2.2	2.0
Headache pain in last month	2.2	3.8	10.3	1.9	1.7	1.8	2.9	3.2	2.7	1.5	1.9	0.9	1.8	1.8	1.5	0.4	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.2	4.6	9.7	-1.8	-2.4	-1.8	-2.5	-1.8	-2.5	-0.8	-1.1	-2.9	-3.1	-1.7	-0.4	-2.6	-2.5
Pack years of smoking	2.2	3.3	5.7	1.6	1.7	1.9	1.8	1.5	1.8	1.9	0.4	2.0	1.6	1.9	2.0	2.4	2.2
Irritable Bowel Disease (IBD)	2.1	5.0	8.3	-2.0	-2.1	-2.1	-2.8	-2.2	-2.9	-1.8	-0.4	-2.7	-2.7	-2.0	-0.8	-2.9	-2.4
Crohns Disease (2012)	2.1	3.4	5.0	-2.0	-2.0	-2.1	-2.0	-0.7	-2.2	-2.1	-0.0	-1.8	-1.7	-2.0	-1.9	-2.2	-1.5
Heel T-Score	2.1	16.4	35.4	-3.4	-2.4	-3.3	-5.9	-5.0	-5.2	-1.7	-3.4	-4.0	-6.0	-3.0	-3.4	-3.1	-4.3
Current tobacco smoking	2.1	3.4	11.0	2.0	1.8	2.3	2.5	1.4	2.5	0.3	1.1	0.2	1.2	2.3	3.3	0.4	1.5
Number of self-reported non-cancer illnesses	2.1	3.6	5.9	2.0	1.7	2.2	2.2	1.6	2.2	1.2	-1.0	1.8	2.0	2.3	1.3	1.7	2.4
Medication: Bendroflumethiazide	2.1	3.1	5.9	1.4	1.1	1.5	2.4	2.2	2.1	0.6	0.4	2.2	2.2	1.6	1.3	2.2	2.1
Frequency of depressed mood in last 2 weeks	2.0	2.9	6.0	2.2	1.2	2.3	1.9	2.4	2.1	0.8	0.6	1.3	1.9	2.0	1.1	0.5	1.7
High blood pressure (mother)	2.0	2.8	4.8	1.8	1.2	1.6	1.7	1.2	1.9	1.7	0.7	2.2	2.1	1.7	1.4	1.9	1.9
Mood swings	2.0	3.7	10.2	2.7	1.1	3.2	1.7	1.7	2.2	1.1	0.5	2.0	1.8	2.5	0.5	1.4	2.3
Ever had bowel cancer screening	2.0	2.4	5.0	-0.6	-1.3	-0.8	-2.2	-1.8	-1.8	-0.3	-1.8	-2.0	-2.2	-1.1	-1.2	-1.6	-1.4
Back pain experienced in last month	2.0	3.0	7.0	2.4	1.3	2.5	2.0	0.2	2.2	1.2	0.2	1.1	1.2	2.6	1.7	1.7	1.6
Ovarian Cancer	1.9	2.5	5.7	-2.3	-1.9	-2.1	-1.6	-1.3	-1.9	-1.7	-0.2	-0.8	-0.8	-2.4	-0.6	-0.9	-1.7
Myopia	1.9	2.8	5.6	-1.5	-1.9	-1.3	-2.4	-1.6	-2.1	-0.5	-1.0	-1.6	-2.0	-1.7	-1.3	-1.9	-1.9
HbA1C	1.8	2.0	5.2	1.8	1.1	2.3	0.8	1.5	1.2	1.6	1.1	1.0	0.7	1.9	1.1	0.4	2.0
Lung FEV1/FVC ratio	1.8	9.1	16.7	-3.0	-3.5	-2.8	-4.1	-2.7	-3.8	-2.9	-1.2	-2.6	-4.0	-2.7	-2.6	-2.3	-2.7
Other serious medical condition/disability diagnosed by doctor	1.8	2.3	3.4	1.7	0.7	1.4	1.8	1.3	1.8	1.7	0.5	1.3	1.4	1.7	1.4	1.8	1.8
Systolic blood pressure, automated reading	1.8	5.1	10.6	2.4	1.8	2.4	1.7	1.5	2.1	1.8	-1.4	3.0	2.1	2.7	2.2	2.4	3.3
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	4.3	1.2	0.9	1.6	1.5	1.2	1.6	0.5	-0.2	1.9	1.8	1.6	0.5	1.4	2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.6	12.8	-2.4	-2.3	-2.4	-1.8	-1.1	-2.2	-1.1	-0.5	-3.6	-2.9	-2.3	-1.2	-3.6	-3.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	7.5	1.2	0.2	1.1	1.9	2.7	1.5	1.5	1.9	0.9	1.5	1.4	0.9	0.3	1.2
Illnesses of father: None of the above (group 1)	1.8	2.3	4.9	-2.0	-1.5	-2.0	-1.4	-1.0	-1.6	-1.2	-1.3	-1.0	-0.8	-2.1	-0.0	-1.2	-2.2
High cholesterol (Self-reported)	1.8	3.2	7.1	1.4	0.7	2.0	1.8	1.8	2.1	1.0	1.1	2.7	2.1	1.9	0.4	2.3	2.2
Systolic Blood Pressure	1.7	8.5	16.6	3.6	2.8	3.6	2.0	1.8	2.9	1.7	-1.4	3.8	2.5	3.8	1.6	3.1	4.1
Townsend deprivation index at recruitment	1.7	2.4	4.0	1.5	1.8	2.0	2.0	1.6	1.8	1.3	-1.0	1.0	1.6	1.6	1.2	1.4	1.5
Eye problems/disorders: Cataract	1.7	2.0	6.1	-1.0	-0.4	-1.1	-1.4	-0.4	-1.4	-0.7	-0.1	-2.5	-1.9	-1.2	0.7	-2.4	-1.9
Smoking status: Current	1.7	2.6	6.2	1.8	1.6	2.1	2.1	1.1	2.3	0.2	0.8	0.6	1.4	2.0	2.5	0.6	1.4
Verbal and Numeric Reasoning (VNR)	1.6	3.9	8.5	-1.8	-1.7	-2.0	-1.6	-1.0	-2.0	-2.0	-2.9	-2.4	-1.9	-2.1	-1.1	-1.9	-2.6
Bipolar Disorder (2011)	1.6	1.6	4.9	1.5	2.2	1.3	0.5	0.6	1.1	1.2	1.9	1.0	0.7	1.4	0.6	1.0	1.2
Medication: Metformin	1.6	2.3	5.5	0.9	0.7	1.1	1.9	2.1	1.6	0.6	0.9	2.3	2.2	0.8	0.5	1.8	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	4.7	1.9	1.1	2.2	1.7	1.2	2.0	0.3	0.9	1.2	1.9	1.9	0.5	0.7	1.7
Diabetes (self-reported)	1.6	2.4	4.8	1.3	1.3	1.4	1.8	1.5	1.8	0.8	1.2	2.2	2.1	1.2	0.2	2.0	1.8
Prospective memory result	1.6	1.9	4.2	1.6	0.8	2.0	1.2	0.5	1.6	-0.3	0.9	1.6	1.1	1.6	1.6	1.7	1.6
Illnesses of father: Heart disease	1.6	2.2	4.7	1.7	1.2	2.0	1.4	0.8	1.6	1.2	1.3	1.4	1.2	1.9	1.0	1.3	2.2
Irritability	1.6	2.7	6.3	1.6	0.9	2.0	1.3	0.7	1.4	1.4	0.8	2.5	2.3	2.0	0.0	2.1	2.0
Unable to work because of sickness or disability	1.6	2.0	6.1	1.2	0.3	1.3	0.9	0.8	1.1	0.6	-1.4	2.5	1.9	1.1	-1.5	2.3	1.4
Alzheimer’s Disease (including proxy)	1.5	2.1	9.6	1.3	0.4	1.2	0.6	0.6	0.7	2.1	0.4	2.2	1.4	1.2	0.1	3.1	1.6
Cardiovascular Disease	1.5	4.9	8.9	2.4	2.3	2.9	2.0	1.6	2.3	1.3	-0.2	2.5	1.5	2.8	1.4	2.9	3.0
Average weekly spirits intake	1.5	1.9	7.5	0.2	1.0	0.1	-0.3	-1.6	-0.3	0.7	0.6	-2.5	-2.2	0.5	2.7	-1.5	-0.7
Medication: Co-codamol	1.5	1.8	4.1	1.5	1.1	1.2	1.0	0.5	1.0	1.5	1.1	2.0	1.5	1.5	0.5	1.8	1.7
Taking other prescription medications	1.5	2.3	4.4	1.7	0.4	2.1	1.5	1.3	1.7	1.4	-1.2	1.6	1.5	2.0	0.8	1.2	1.9
Medication: Atenolol	1.5	1.9	7.0	0.6	0.9	1.0	1.3	0.8	1.3	0.4	0.3	2.7	2.1	0.7	-0.2	2.1	1.8
Number of incorrect matches in round	1.5	2.5	4.5	1.8	1.8	1.8	1.9	0.7	1.9	1.2	-0.4	1.7	1.9	1.6	1.1	1.2	2.1
Pain all over the body in last month	1.5	1.6	4.2	1.9	-0.3	2.1	0.9	-0.5	1.5	-0.2	-0.1	1.2	1.0	2.0	0.2	0.5	1.9
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	5.7	1.2	-0.0	1.9	2.1	2.0	2.1	0.8	-0.9	1.7	2.4	1.6	-0.1	0.6	2.0
Forced expiratory volume in 1-second (FEV1)	1.5	5.2	13.9	-1.9	-1.8	-2.0	-1.8	-1.3	-2.1	-0.9	-0.8	-3.7	-3.0	-2.0	-1.3	-3.6	-3.0
High blood pressure (siblings)	1.5	2.1	5.4	1.9	1.9	2.0	0.8	0.7	1.2	0.7	-0.0	1.7	0.8	1.9	0.4	2.3	1.9
Medication: Ibuprofen	1.5	1.8	7.7	1.0	1.2	0.9	1.5	1.6	1.4	1.3	2.8	0.7	1.2	1.2	1.0	0.1	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	4.2	1.1	0.9	1.6	1.0	1.6	1.3	0.6	-0.9	2.0	1.7	1.3	0.4	1.6	1.9
Diastolic blood pressure, automated reading	1.5	4.5	7.8	2.2	2.0	2.0	2.2	2.3	2.3	2.2	-0.5	1.8	1.4	2.5	2.8	2.1	2.5
Cholesterol lowering medication	1.5	2.2	3.7	1.3	0.4	1.9	1.7	1.4	1.9	0.5	1.1	1.6	1.5	1.7	1.6	1.4	1.8
Type 2 Diabetes (T2D) (2018)	1.4	2.6	8.1	1.0	0.9	1.2	1.6	1.4	1.6	0.1	0.6	2.9	2.5	1.0	-0.3	2.5	2.0
Supplements: Zinc	1.4	1.5	4.4	1.5	0.3	1.6	1.4	1.1	1.4	1.4	1.3	0.1	0.6	1.2	2.1	-0.4	0.5
Long-standing illness, disability or infirmity	1.4	2.1	4.5	2.1	0.4	2.0	1.0	0.3	1.7	0.8	-1.5	1.5	1.4	2.1	0.3	1.7	1.7
Medication: Blood pressure	1.4	2.7	6.7	1.8	1.3	2.6	1.5	0.6	2.0	1.2	0.7	1.6	1.4	2.2	1.2	1.2	2.3
Pain experienced in last month	1.4	2.3	4.6	-1.7	-0.8	-2.1	-1.8	-0.5	-2.0	-1.5	-0.8	-1.3	-1.6	-2.1	-1.2	-1.1	-1.6
Depressed Affect (Nagel 2018)	1.3	2.7	6.2	2.2	1.0	2.5	1.9	1.4	2.1	2.4	0.8	0.4	1.1	1.9	1.6	-0.3	1.5
Triglycerides	1.3	2.1	4.0	1.0	1.3	1.4	1.5	0.9	1.8	1.2	1.1	1.8	2.0	1.2	0.4	1.6	1.9
Ever used hormone-replacement therapy (HRT)	1.3	1.6	4.4	1.2	0.7	1.6	2.1	1.4	1.6	1.3	-0.5	0.8	1.4	1.2	1.3	0.7	1.1
Past tobacco smoking	1.3	2.5	5.3	-1.9	-0.9	-2.3	-1.5	-1.9	-2.3	-0.6	0.7	-1.2	-1.5	-1.8	-0.8	-1.3	-1.7
Hair/balding pattern: Pattern 3	1.3	1.9	4.7	-1.3	-2.1	-1.1	-1.6	-1.2	-1.5	-1.1	-0.6	-1.4	-2.2	-1.2	-0.7	-1.1	-1.1
Birth weight of first child	1.3	2.3	7.4	-0.9	-0.5	-1.0	-1.2	-0.7	-1.1	-0.5	1.7	-2.7	-2.0	-1.1	0.6	-2.5	-2.0
Forced vital capacity (FVC), Best measure	1.3	4.7	15.3	-2.3	-1.4	-2.5	-0.6	-0.5	-1.5	-0.8	-0.3	-3.9	-2.2	-2.2	-0.2	-3.7	-3.2
Diabetes diagnosed by doctor	1.3	2.1	5.4	1.1	0.7	1.1	1.6	1.6	1.7	0.1	1.3	2.3	2.1	1.0	-0.3	1.8	1.7
Medication: Gliclazide	1.3	1.5	5.1	0.3	-0.4	0.1	1.9	2.3	1.4	0.2	0.8	1.5	1.8	0.5	1.1	0.7	1.4
Chronotype (morning person)	1.2	2.8	7.7	-1.5	-2.3	-1.3	-2.8	-1.8	-2.5	-1.1	-0.7	-1.1	-2.1	-1.4	-0.6	-0.4	-1.7
Blood clot in the leg (DVT)	1.2	1.5	3.5	-1.6	-1.4	-1.4	-0.4	-0.2	-1.0	-0.1	-1.8	-1.4	-0.9	-1.6	-0.1	-1.3	-1.9
Pulse rate, automated reading	1.2	3.9	9.1	1.7	2.0	1.7	3.0	2.8	2.8	1.9	0.4	0.8	1.6	2.0	1.9	1.2	2.0
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	6.2	-0.6	-1.7	-0.9	-0.9	-0.8	-0.7	-1.3	-2.5	0.1	0.3	-0.8	-1.4	-0.9	-0.4
Osteoarthritis (self-reported)	1.2	1.5	3.1	1.2	-0.6	1.6	0.3	0.6	1.1	0.8	1.0	1.8	1.7	1.5	-0.1	1.6	1.7
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	3.7	-1.5	-1.6	-1.5	-0.5	-0.3	-1.1	-0.3	-1.7	-1.4	-0.9	-1.6	-0.2	-1.2	-1.9
Alcohol drinker status: Previous	1.2	1.4	6.2	-0.3	-0.3	-0.0	-1.2	-1.4	-0.7	-1.0	0.1	-2.2	-2.5	-0.3	-0.3	-1.2	-1.3
Rheumatoid Arthritis	1.1	1.5	5.4	0.4	-0.8	0.5	-2.0	-2.3	-1.3	-0.9	-1.4	-1.0	-2.0	0.3	-0.0	-0.2	-0.6
Vitamin and mineral supplements	1.1	1.5	4.2	-1.0	-1.4	-0.8	-2.1	-1.9	-1.5	-0.8	-1.8	-0.1	-1.2	-0.8	-1.0	-0.2	-0.5
Qualifications: CSEs or equivalent	1.1	1.5	4.1	1.5	0.1	1.8	0.7	0.5	1.4	-0.3	0.5	1.3	0.9	1.8	0.2	2.0	1.6
Illnesses of siblings	1.1	1.6	3.8	-1.8	-1.5	-1.9	-0.8	-1.0	-1.2	-0.3	-0.4	-1.2	-0.5	-1.6	-0.4	-1.7	-1.4
Pulse rate	1.1	1.9	4.6	0.7	1.1	0.9	2.1	1.6	1.5	1.7	0.0	1.1	1.1	1.1	1.8	1.4	1.6
Number of full brothers	1.1	1.4	3.5	1.1	1.6	1.9	0.6	-0.0	0.9	1.6	-1.1	0.6	0.7	1.4	1.4	1.5	0.9
Wheeze or whistling in the chest in last year	1.1	2.0	6.3	0.3	-0.9	0.9	1.4	1.3	1.2	0.1	-0.0	2.4	2.5	0.7	0.0	2.5	1.7
Medication: Seretide 50 evohaler	1.1	1.3	4.8	-1.2	-2.2	-1.1	-0.9	0.9	-1.0	-0.8	-2.0	-0.2	-0.5	-1.1	-0.5	-0.2	-1.1
Smoking status: Previous	1.1	1.7	4.6	1.3	0.3	1.7	1.4	2.1	1.8	1.1	-0.5	0.8	1.1	1.3	0.8	1.3	1.2
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.2	1.2	1.6	1.3	1.7	1.8	1.4	0.9	1.0	0.5	0.7	1.2	0.6	0.8	1.0
Blood Eosinophil Count	1.0	8.0	15.3	3.2	2.0	3.6	2.4	2.1	3.1	2.4	1.7	3.3	2.9	3.5	0.9	3.0	3.9
Hearing difficulty/problems: Yes	1.0	1.5	2.3	1.2	0.7	1.5	1.2	1.3	1.4	1.4	0.4	1.3	1.3	1.3	0.7	1.5	1.4
Alcohol intake versus 10 years previously	1.0	1.5	6.3	-0.2	-0.1	0.0	0.9	-0.2	0.5	0.2	-0.3	2.5	2.2	0.1	-1.9	2.0	0.8
Happiness	1.0	1.3	2.8	0.7	0.6	1.2	1.4	1.7	1.3	1.1	-0.3	1.2	1.3	1.1	0.4	1.4	0.9
Mouth/teeth dental problems: Dentures	1.0	1.7	3.5	1.0	1.8	1.9	1.4	1.1	1.4	1.2	-0.5	0.7	1.1	1.4	1.4	0.5	1.5
Impedance of arm (left)	1.0	4.8	8.0	-1.6	-1.4	-2.2	-2.7	-2.5	-2.6	-1.7	-0.7	-2.6	-2.4	-2.2	-1.8	-2.6	-2.8
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.8	-1.4	-1.7	-1.4	-1.3	-0.3	-1.4	0.3	0.0	-1.6	-1.2	-1.5	-0.5	-1.5	-1.6
Birth weight	1.0	2.2	5.8	-2.4	-1.9	-2.3	0.2	-0.0	-1.0	-0.5	-1.1	-1.6	-0.7	-2.1	-0.2	-1.5	-1.9
Chronic bronchitis/emphysema (mother)	1.0	1.2	4.5	1.0	0.3	1.1	0.5	-0.1	0.7	-0.9	-0.7	1.8	1.3	1.0	0.6	2.1	1.4
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.7	-1.2	-0.7	-1.7	0.9	2.2	-0.0	0.5	1.8	-0.4	0.3	-1.2	-0.1	-1.2	-0.6
Number of operations (self-reported)	1.0	1.5	7.2	-1.2	-2.0	-0.9	-0.8	-0.4	-1.2	-1.0	-2.7	-0.8	-0.7	-1.1	0.2	-0.5	-1.1
Allergy or Eczema	0.9	2.3	5.4	-1.7	-2.0	-1.9	-1.7	-1.6	-2.0	-2.3	-1.3	-0.3	-0.9	-1.8	-0.8	-0.3	-1.1
Diabetes (mother)	0.9	1.1	3.7	-0.4	-1.1	-0.1	-1.4	-0.9	-0.8	-0.9	1.0	1.9	0.8	-0.4	-1.6	1.4	0.6
Body mass index (BMI)	0.9	3.8	13.7	-0.7	-2.1	0.1	1.7	1.6	0.9	1.6	-0.5	3.7	3.1	0.1	0.3	3.4	2.2
Forced vital capacity (FVC)	0.9	3.4	14.2	-1.5	-0.9	-1.7	-0.2	-0.4	-0.9	-0.3	-0.4	-3.8	-2.1	-1.5	0.1	-3.5	-2.5
Mouth/teeth dental problems	0.9	1.4	5.2	-1.4	-1.5	-2.3	-0.7	-0.1	-1.0	-0.7	-0.6	-0.7	-0.8	-1.7	-1.0	-0.8	-1.4
Peak expiratory flow (PEF)	0.9	2.2	5.3	-1.1	-1.6	-1.3	-1.6	-1.6	-1.3	-0.9	0.0	-1.2	-1.5	-1.1	-2.3	-2.1	-1.5
Ever highly irritable/argumentative for 2 days	0.9	1.1	4.1	0.1	0.1	0.5	0.6	2.0	0.6	0.8	0.3	1.9	1.5	0.3	-1.1	1.2	1.1
Migraine (self-reported)	0.9	1.1	2.2	1.1	0.4	1.2	1.3	0.9	1.1	1.5	-0.2	0.9	1.2	1.0	1.1	1.2	1.0
Average weekly beer plus cider intake	0.9	1.2	3.5	0.3	1.2	0.9	1.4	1.5	1.2	0.5	1.9	0.9	1.5	0.5	-0.5	1.3	0.5
Leg fat mass (left)	0.9	3.5	9.9	-0.6	-2.0	0.1	1.9	2.1	1.1	1.5	0.0	3.1	3.0	0.1	0.8	3.0	1.9
Prostate Cancer	0.8	1.1	3.5	-0.3	-1.9	-0.3	-1.4	-1.4	-0.9	-1.7	-0.8	-1.0	-0.9	-0.4	0.3	-0.6	-0.5
Body Mass Index (BMI) (2010)	0.8	1.1	3.2	-1.6	-0.9	-1.6	-0.7	-0.4	-1.0	-0.4	-0.0	-0.4	-0.3	-1.4	-1.8	-0.8	-0.9
Schizophrenia (2014)	0.8	1.8	6.6	1.8	2.6	1.2	0.7	1.6	1.1	2.1	-0.3	-0.9	-0.4	1.4	0.8	-1.3	0.6
Neuroticism	0.8	2.0	8.3	1.9	0.5	2.3	0.7	0.2	1.4	2.9	-1.0	0.8	0.9	1.8	0.4	0.2	1.4
Chronic bronchitis/emphysema (father)	0.8	0.9	2.4	1.1	0.6	0.9	0.7	0.6	0.8	-0.1	1.2	1.3	1.0	1.2	0.1	1.6	1.1
Waist circumference	0.8	3.1	8.3	-1.0	-1.8	-0.2	2.4	2.3	1.3	1.4	0.4	2.5	2.9	-0.3	1.1	2.4	1.5
Hearing difficulty/problems with background noise	0.8	1.2	4.8	0.8	0.1	0.9	1.2	2.2	1.0	0.6	0.2	1.2	1.3	0.9	0.2	1.5	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.9	6.6	-0.9	-1.8	-0.6	-2.6	-1.1	-2.0	-0.5	-1.6	-0.6	-2.0	-0.9	-1.0	-0.4	-1.2
Arm fat percentage (right)	0.8	3.1	11.2	-1.0	-2.6	-0.6	1.1	1.1	0.4	0.9	-0.5	3.3	2.9	-0.5	-0.2	3.0	1.7
Number of live births	0.8	1.1	4.0	0.3	0.2	0.4	1.6	2.0	1.0	0.7	-1.3	0.7	1.5	0.4	1.2	0.4	0.7
Illnesses of mother	0.8	1.0	4.5	-0.6	0.2	-1.1	0.8	1.4	0.1	-0.1	2.1	-1.0	-0.2	-0.9	-0.4	-1.7	-0.7
Arm fat mass (right)	0.8	3.2	9.2	-1.1	-2.4	-0.7	2.0	2.1	0.9	1.0	-0.0	2.9	3.0	-0.6	0.5	2.6	1.6
Medication: Ventolin 100micrograms inhaler	0.8	1.0	3.8	-1.3	-1.9	-1.3	-0.7	-0.3	-1.1	-1.2	1.3	-0.3	-0.4	-1.1	-0.2	0.3	-0.8
Worry too long after embarrassment	0.8	1.4	7.5	-1.1	-2.7	-1.1	-0.7	-0.9	-0.8	-0.6	-1.9	-0.4	-0.3	-1.1	-0.8	-0.6	-0.9
Leg fat mass (right)	0.8	3.2	8.8	-0.6	-1.9	0.0	1.9	2.2	1.1	1.5	-0.1	3.0	2.9	-0.0	0.6	2.8	1.9
Age at last live birth	0.8	1.2	3.6	-1.8	-1.1	-1.9	-0.8	0.3	-1.4	0.2	0.2	-0.3	-0.2	-1.8	-0.5	-1.0	-1.2
Arm fat percentage (left)	0.8	3.0	10.1	-1.4	-3.0	-0.8	0.9	0.9	0.1	0.9	-0.7	3.2	2.7	-0.7	-0.2	2.9	1.4
Arm fat mass (left)	0.8	3.2	8.4	-1.6	-2.7	-1.1	1.7	1.9	0.5	0.9	-0.1	2.8	2.9	-1.0	0.3	2.7	1.1
Leg fat percentage (left)	0.8	3.0	11.0	-0.2	-1.9	0.6	1.0	1.1	0.6	1.9	-0.6	3.3	2.3	0.5	0.9	3.2	2.1
Crohns Disease (2017)	0.7	1.5	3.5	-0.7	-1.3	-0.8	-1.8	-1.5	-1.6	-1.9	0.5	-0.8	-1.1	-0.8	-0.9	-1.1	-0.8
Age at First Birth	0.7	1.0	6.9	-1.0	-1.2	-1.1	0.1	0.6	-0.3	-2.6	0.9	0.5	0.7	-1.1	-0.5	-0.0	-0.5
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.3	1.2	1.4	0.4	0.6	0.7	0.8	0.7	-0.3	0.9	1.0	1.3	-0.3	0.5	1.5
Diabetes (father)	0.7	0.9	2.4	-1.2	-1.5	-1.1	-0.7	-0.8	-1.1	-0.7	-1.0	-0.6	-0.8	-0.8	-0.4	-0.5	-1.0
Maternal smoking around birth	0.7	1.0	2.5	-1.5	-0.7	-1.3	0.2	-0.3	-0.3	-1.6	-1.3	0.3	1.2	-1.0	-1.4	-0.6	-0.3
Weight	0.7	3.3	9.9	-1.7	-2.2	-1.3	2.6	2.7	1.0	0.7	0.5	2.1	3.1	-1.2	1.0	1.9	0.8
Impedance of arm (right)	0.7	3.3	5.3	-1.2	-0.8	-1.9	-2.3	-2.1	-2.0	-1.5	-0.2	-2.1	-1.9	-1.8	-1.8	-2.1	-2.2
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.6	-1.3	-1.5	-1.9	-1.1	-0.2	-1.4	-0.6	-0.4	-0.9	-0.9	-1.6	-1.4	-1.3	-1.4
Length of working week for main job	0.7	0.8	2.0	-1.4	-1.0	-1.4	-0.5	0.4	-0.8	-1.0	-0.0	0.7	0.6	-1.3	-1.1	0.5	-0.3
Medication: Paracetamol	0.7	1.1	3.1	1.6	1.2	1.7	0.9	0.5	1.3	0.4	0.1	0.1	0.8	1.8	0.7	-0.8	0.8
Leg fat percentage (right)	0.7	2.5	8.9	-0.1	-1.6	0.6	1.0	1.2	0.6	1.9	-0.7	3.0	2.0	0.5	0.7	2.8	2.0
Comparative body size at age 10	0.7	1.8	9.1	-1.1	-3.0	-1.0	-1.4	-0.9	-1.1	-1.1	-1.0	-0.6	-1.1	-1.3	-1.9	-0.3	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.8	1.0	-0.3	0.8	-0.1	-0.8	0.6	1.3	-0.2	1.4	0.7	1.2	-1.1	0.8	1.3
Qualifications: College or University degree	0.7	2.2	5.5	-1.5	-1.0	-2.3	-0.7	0.3	-1.2	-0.4	-0.6	-2.0	-1.2	-2.0	0.2	-2.3	-2.0
Alcohol intake frequency.	0.7	1.6	4.2	-2.0	-2.0	-1.6	-0.7	-0.5	-1.5	-1.0	-0.5	0.2	-0.2	-1.6	-2.0	0.0	-1.2
Miserableness	0.7	1.1	3.0	1.1	0.6	1.7	1.4	1.2	1.4	0.5	-0.4	0.7	1.1	1.3	0.6	0.7	1.1
Financial situation satisfaction	0.7	0.8	2.7	0.8	0.2	1.3	0.6	0.4	1.0	1.4	-1.0	0.3	0.5	1.0	1.6	0.7	0.6
Illnesses of father: High blood pressure	0.7	0.9	2.1	1.1	1.0	1.0	1.4	1.1	1.5	0.2	0.2	0.6	0.9	1.0	-0.8	-0.0	1.3
Impedance of whole body	0.7	3.7	8.3	-0.6	-0.4	-1.0	-2.8	-2.6	-2.2	-0.9	-0.2	-2.8	-2.9	-1.1	-1.0	-2.5	-2.3
Bipolar Disorder or Schizophrenia	0.6	1.4	4.8	2.0	2.2	1.3	-0.4	0.7	0.6	1.2	-1.6	-0.7	-0.8	1.3	0.0	-1.2	0.3
Alzheimer’s Disease (in father)	0.6	0.6	3.2	0.5	0.3	0.6	0.3	0.7	0.1	1.4	-1.0	0.8	0.2	0.4	-0.3	1.8	0.6
Fasting Glucose	0.6	0.7	1.5	1.2	0.4	1.0	-0.2	-0.4	0.5	-0.1	-1.1	0.8	0.7	1.1	1.2	1.0	1.0
HDL Cholesterol	0.6	1.0	3.4	0.1	-0.2	-0.2	-1.3	-0.9	-0.7	0.3	0.6	-1.8	-1.8	-0.1	-0.4	-1.5	-0.9
Primary Biliary Cirrhosis	0.6	0.8	2.1	-0.5	0.4	-0.9	-1.0	-1.2	-1.0	0.1	-0.1	-1.2	-1.4	-0.5	-1.3	-1.3	-0.5
Sensitivity / hurt feelings	0.6	1.1	3.3	1.7	0.3	1.8	0.1	-0.5	1.0	1.5	-1.0	0.5	0.4	1.6	0.9	0.4	1.0
Medication for hormone replacement therapy	0.6	0.6	2.4	1.4	0.2	1.5	0.1	1.5	0.5	0.4	0.1	-0.1	-0.5	0.9	-0.4	0.1	0.5
Leg fat-free mass (left)	0.6	3.0	8.6	-2.0	-2.3	-1.7	2.6	2.9	1.0	-0.1	0.5	1.2	2.8	-1.7	0.7	0.8	0.0
Age when periods started (menarche)	0.6	1.4	5.7	1.3	2.3	1.4	0.2	-0.3	0.7	0.4	2.4	0.4	0.2	1.2	1.5	0.9	0.4
Leg predicted mass (left)	0.6	3.0	8.3	-2.0	-2.3	-1.7	2.6	2.9	1.0	-0.2	0.5	1.1	2.7	-1.7	0.7	0.8	-0.1
Trunk fat mass	0.6	2.6	8.2	-1.8	-2.9	-1.3	1.6	1.8	0.3	0.9	0.1	2.0	2.5	-1.2	0.7	1.9	0.7
Hair/balding pattern: Pattern 2	0.6	0.7	2.8	0.7	0.5	0.7	0.9	0.4	1.2	0.9	-0.0	1.0	1.7	0.6	0.8	0.4	0.7
Had menopause	0.6	0.8	2.6	-1.0	-1.0	-0.5	-0.5	-0.4	-0.6	-0.4	-1.6	-1.3	-1.1	-0.9	-0.2	-0.6	-0.9
Hip circumference	0.6	2.7	8.3	-1.9	-2.2	-1.4	1.7	1.5	0.3	0.5	0.1	2.5	2.9	-1.4	0.9	1.9	0.8
Father’s age at death	0.6	0.9	1.9	-0.7	-0.6	-1.2	-0.2	0.4	-0.4	-1.2	-1.0	-1.4	-0.6	-1.1	-0.8	-1.4	-1.1
Lung cancer (father)	0.6	0.7	2.5	0.1	-0.4	0.3	1.1	0.7	0.8	-0.1	-0.2	1.4	1.6	0.2	0.5	1.1	0.8
Standing height	0.6	5.8	12.0	-2.6	-0.6	-3.1	2.2	2.8	0.2	-1.8	2.1	-3.5	0.2	-3.0	1.9	-3.2	-3.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.8	1.0	-1.0	1.1	0.9	1.7	1.1	0.4	-0.6	0.8	1.2	1.0	0.1	0.5	0.9
Pulse wave peak to peak time	0.6	0.7	2.0	-0.8	-0.5	-0.5	-0.6	-0.8	-0.7	-0.0	-0.3	-1.3	-1.4	-0.7	-1.1	-0.4	-1.0
Neck or shoulder pain in last month	0.6	0.9	2.1	0.8	0.0	0.9	0.9	0.8	1.1	0.5	0.8	1.2	1.5	1.0	0.4	1.4	0.9
Whole body fat mass	0.6	2.4	7.2	-1.7	-2.7	-1.1	1.5	1.9	0.3	0.9	-0.1	2.1	2.4	-1.1	0.6	1.8	0.8
Number of full sisters	0.6	0.7	2.2	0.7	1.2	1.5	0.1	-0.7	0.2	-0.2	0.4	1.1	0.5	1.0	-0.2	1.4	0.9
Leg pain on walking	0.6	0.8	3.8	0.6	-0.1	1.0	-0.4	-0.1	0.1	1.5	-1.9	0.9	0.6	0.8	-0.5	0.5	1.0
Leg fat-free mass (right)	0.6	3.0	7.8	-2.2	-2.4	-1.9	2.5	2.6	0.9	-0.4	0.5	1.1	2.8	-1.8	0.7	0.7	-0.2
Osteoporosis (self-reported)	0.6	0.8	2.7	-0.9	-0.1	-1.2	-0.3	-0.4	-0.7	-1.0	-0.3	-1.4	-0.6	-0.9	0.0	-1.6	-1.1
Leg predicted mass (right)	0.6	3.1	8.1	-2.2	-2.4	-1.9	2.5	2.6	0.9	-0.5	0.5	1.1	2.9	-1.8	0.6	0.7	-0.2
Guilty feelings	0.6	0.9	4.6	-0.4	-1.5	-0.2	-0.0	1.0	-0.0	-0.1	-2.2	-0.1	0.3	-0.7	-1.8	-1.0	-0.4
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.3	-0.8	-1.2	-0.4	-0.9	-0.2	-0.8	-1.1	-1.5	-0.2	-0.2	-0.5	-1.4	-0.6	-0.4
Medication: Paracetamol	0.6	1.0	2.8	1.6	1.2	1.4	0.5	0.4	0.9	0.2	1.0	0.5	0.8	1.7	1.0	-0.2	0.8
Medication: Atorvastatin	0.6	0.8	3.7	0.2	0.6	0.3	-0.5	-0.3	-0.1	-0.4	-1.4	1.4	0.4	0.0	-1.9	1.3	0.7
Fractured/broken bones in last 5 years	0.6	0.7	5.8	0.0	-1.2	0.3	0.7	2.4	0.5	-0.8	0.5	0.5	1.0	-0.2	-0.5	0.2	-0.0
Ever depressed for a whole week	0.6	0.8	5.9	1.4	0.4	0.9	-0.6	0.2	0.2	-0.6	-2.4	0.3	0.0	0.9	-0.4	0.1	0.5
Supplements: Calcium	0.6	0.6	2.9	0.3	0.1	0.3	0.6	0.0	0.4	0.1	-0.1	-1.7	-0.8	0.3	1.6	-1.3	-0.5
Schizophrenia (2018)	0.5	1.1	4.1	1.5	2.0	0.9	-0.6	0.2	0.2	0.7	-1.9	-0.7	-1.1	1.1	-0.3	-0.8	0.2
Alzheimer’s Disease (in mother)	0.5	0.5	2.1	0.8	-0.2	0.7	-0.5	-1.1	0.0	0.8	0.5	0.9	0.5	0.7	0.3	1.4	0.5
Mean Putamen Volume	0.5	0.6	1.9	-0.4	0.5	-0.3	-1.1	-0.5	-0.7	-0.7	1.0	-0.8	-1.4	-0.1	-0.2	-0.7	-0.7
BMI	0.5	3.2	10.2	-1.3	-2.4	-0.7	1.4	1.5	0.5	-0.5	-1.2	3.2	2.9	-0.6	-0.1	3.0	1.6
Lung FVC	0.5	2.5	9.2	-0.6	-0.7	-0.5	-1.2	-1.5	-1.0	-0.4	-1.4	-2.9	-2.6	-0.6	0.0	-3.0	-1.6
Relative age of first facial hair	0.5	1.1	2.6	1.3	1.1	1.5	0.8	0.7	1.4	1.5	0.5	0.5	0.4	1.6	0.5	0.4	1.2
Trunk fat percentage	0.5	2.0	8.8	-1.7	-3.0	-1.2	0.6	0.7	-0.2	0.9	-0.0	2.0	1.9	-1.2	0.2	1.9	0.6
Fed-up feelings	0.5	0.9	2.7	0.6	-0.5	1.4	1.6	1.1	1.3	1.0	0.2	0.2	1.0	0.8	1.1	-0.1	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	5.2	-0.8	-1.3	-0.5	-2.3	-1.1	-1.7	-0.1	-0.8	0.0	-1.5	-0.6	-1.2	0.4	-0.7
Multivitamins +/- minerals	0.5	0.6	2.6	0.7	1.4	0.3	0.9	-0.5	0.8	0.1	1.6	0.4	0.9	0.4	-0.7	0.1	0.5
Sitting height	0.5	3.2	11.8	-1.2	0.2	-1.1	3.0	3.4	1.6	-0.8	2.2	-0.9	1.6	-1.1	2.7	-1.0	-0.8
Pulse wave Arterial Stiffness index	0.5	0.6	2.5	0.5	0.4	0.2	0.7	1.0	0.6	-0.3	0.2	1.2	1.6	0.4	1.0	0.3	0.8
Body fat percentage	0.5	2.2	7.8	-1.4	-2.8	-0.8	0.7	0.9	-0.1	1.1	-0.4	2.5	2.1	-0.8	0.2	2.2	1.1
Shortness of breath walking on level ground	0.5	0.6	1.8	0.4	-0.2	0.4	0.6	1.3	0.5	0.4	-0.5	1.1	1.1	0.5	0.2	1.3	0.9
Heart disease (mother)	0.5	0.6	1.8	-0.1	-0.5	0.7	-0.7	-0.9	-0.4	0.9	-1.3	-1.0	-1.3	0.2	-0.4	-0.7	-0.8
Arm predicted mass (right)	0.5	2.5	10.2	-1.4	-1.1	-0.9	2.8	3.2	1.4	0.2	0.6	0.9	2.4	-0.9	1.6	0.9	0.3
Comparative height size at age 10	0.5	2.7	5.1	-2.0	-1.6	-2.2	1.1	1.9	-0.1	-2.2	-1.0	-1.6	0.8	-2.2	0.6	-2.0	-1.6
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	3.5	0.1	0.9	-0.1	-1.1	-1.9	-0.5	-0.3	0.3	-0.3	-0.5	-0.2	-1.1	-0.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	4.5	-0.2	0.5	-0.3	1.7	2.1	0.9	-0.2	1.6	-0.7	0.7	-0.2	0.9	-0.5	-0.2
Loneliness, isolation	0.5	0.7	2.8	0.4	0.3	0.4	1.2	1.7	0.9	-0.4	-0.5	0.8	1.7	0.3	-0.4	-0.0	0.5
Friendships satisfaction	0.5	0.6	1.7	0.5	0.7	0.8	0.8	0.8	1.1	0.2	-0.8	1.2	1.3	0.6	0.0	0.6	0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	3.4	-1.0	-1.3	-1.0	-0.7	-0.4	-0.9	-0.4	-0.7	-0.1	-0.1	-1.4	-1.8	0.1	-0.9
Average weekly champagne plus white wine intake	0.5	0.6	3.0	0.0	0.4	-0.0	-0.1	-1.7	-0.2	-0.4	0.9	-1.2	-0.6	-0.1	0.9	-1.0	-0.9
Alcohol drinker status: Never	0.5	0.6	1.9	-1.4	-0.8	-1.1	0.5	0.5	-0.5	0.1	-0.0	0.5	0.9	-1.2	-0.6	-0.3	-0.6
Ever smoked	0.5	0.9	2.5	1.1	0.8	1.5	1.0	0.5	1.6	0.7	-0.7	0.5	0.9	1.1	0.2	0.3	0.9
Basal metabolic rate	0.5	2.8	10.1	-1.7	-1.6	-1.5	2.8	3.2	1.2	-0.1	0.6	0.9	2.6	-1.4	1.3	0.8	0.2
Risk taking	0.5	0.8	1.8	1.1	1.0	1.3	0.8	0.7	1.1	0.0	1.1	0.8	0.6	0.8	0.6	1.1	0.6
Ever had prostate specific antigen (PSA) test	0.5	0.5	2.5	0.9	0.3	0.2	0.4	0.8	0.5	1.0	0.8	-0.6	-0.1	0.4	1.6	-0.4	0.5
Arm predicted mass (left)	0.5	2.6	10.8	-1.3	-1.1	-0.9	2.9	3.3	1.4	0.2	0.9	0.9	2.4	-0.9	1.7	0.9	0.4
Bipolar Disorder (2018)	0.4	0.6	1.8	1.4	1.0	0.9	0.2	1.0	0.7	1.0	-0.3	-0.2	0.1	0.8	0.6	-1.0	0.3
Neuroticism (Nagel 2018)	0.4	0.9	4.6	1.5	-0.4	1.5	0.2	-0.1	0.9	2.2	-0.7	-0.0	0.4	1.1	0.1	-0.8	0.7
Lupus	0.4	0.7	3.7	0.8	0.6	0.8	-0.9	-1.9	-0.0	-0.3	-0.2	-0.6	-0.8	0.9	0.9	-0.3	0.3
Height	0.4	7.8	15.9	-3.6	-1.3	-4.0	3.1	3.6	0.4	-0.9	1.8	-3.3	1.0	-3.7	2.0	-3.1	-3.5
Waist Hip Ratio (WHR)	0.4	1.9	5.2	1.3	0.8	1.7	1.6	1.9	1.6	2.3	1.5	-0.5	0.2	1.3	1.5	0.2	0.7
Hand grip strength (left)	0.4	1.2	7.1	0.0	1.1	-0.5	1.4	1.7	0.7	-0.0	2.7	-0.1	0.6	-0.3	1.4	-0.3	-0.3
Impedance of leg (right)	0.4	2.2	7.9	1.0	1.7	0.7	-2.1	-1.5	-1.2	-0.2	0.1	-2.4	-2.8	0.5	-0.1	-1.8	-1.1
Hand grip strength (right)	0.4	1.1	2.9	-1.1	-0.2	-1.7	0.2	0.6	-0.6	-0.4	1.4	-1.2	-0.5	-1.4	0.4	-1.2	-1.7
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.6	-0.0	0.0	-0.1	0.6	0.3	0.3	1.3	-0.4	1.2	1.1	0.1	-0.2	0.9	0.7
Impedance of leg (left)	0.4	1.9	6.3	0.9	1.3	0.6	-2.1	-1.9	-1.2	-0.2	0.4	-2.0	-2.5	0.5	0.2	-1.5	-1.0
Neuroticism score	0.4	0.9	2.6	1.3	-0.1	1.6	0.3	0.4	0.8	0.4	-1.2	1.1	1.1	1.2	-0.7	0.6	1.1
Trunk fat-free mass	0.4	2.2	10.2	-1.4	-0.7	-1.4	2.7	3.2	1.2	-0.5	0.4	-0.2	1.8	-1.2	1.5	-0.2	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.4	-0.8	-0.6	-1.2	-0.3	1.1	-0.8	-0.3	0.1	-0.5	-0.6	-0.8	-0.6	-0.5	-0.8
Asthma	0.4	0.8	2.5	-0.8	-0.7	-0.9	0.3	0.6	-0.1	-0.3	0.2	1.6	1.4	-0.6	-1.2	1.4	0.4
Trunk predicted mass	0.4	2.2	9.9	-1.5	-0.7	-1.5	2.6	3.1	1.1	-0.6	0.3	-0.2	1.7	-1.3	1.4	-0.2	-0.4
Tense / ‘highly strung’	0.4	0.6	2.9	1.7	0.3	1.4	-0.0	0.6	0.7	0.8	0.0	0.5	0.5	1.1	0.0	0.5	0.7
Pulse wave reflection index	0.4	0.4	1.8	0.5	-0.2	0.7	-0.7	-0.6	-0.3	-0.6	-0.1	-0.7	-0.7	0.5	1.4	-0.9	-0.4
Arm fat-free mass (right)	0.4	2.1	8.2	-1.5	-1.4	-1.0	2.5	2.9	1.1	-0.0	0.2	0.4	2.0	-1.1	1.6	0.5	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.0	1.4	0.1	1.2	-0.0	-0.3	0.7	0.4	-0.2	0.1	-0.2	1.1	-0.7	0.5	0.6
Chest pain or discomfort	0.4	0.6	2.0	-0.3	-1.1	-0.0	0.8	1.1	0.2	0.4	-0.2	1.2	0.8	-0.2	0.7	1.4	0.2
Commuting to job workplace: Car/motor vehicle	0.4	0.4	3.3	0.4	-0.2	0.7	0.5	0.5	0.8	0.4	1.8	-0.1	0.2	0.5	0.5	-0.0	0.4
Whole body fat-free mass	0.4	2.5	9.7	-1.7	-1.4	-1.5	2.8	3.1	1.1	-0.4	0.5	0.4	2.3	-1.4	1.2	0.2	-0.2
Mineral and other dietary supplements	0.4	0.5	2.1	-0.7	-1.5	-0.7	-0.6	-0.6	-0.6	-0.5	-1.2	0.0	0.0	-0.9	-0.4	-0.1	-0.6
Whole body water mass	0.4	2.6	9.5	-1.8	-1.4	-1.6	2.7	3.1	1.1	-0.4	0.5	0.5	2.3	-1.5	1.1	0.3	-0.2
Wears glasses or contact lenses	0.4	0.4	1.5	0.3	0.4	0.6	0.1	-0.6	0.2	0.3	-1.1	-1.2	-1.1	0.5	0.9	-0.5	0.1
Mother’s age at death	0.4	0.5	2.0	-0.4	0.8	-0.7	0.1	0.5	-0.2	-0.9	-1.4	-0.6	-0.3	-0.6	1.1	-0.7	-0.3
Tinnitus: Yes, now most or all of the time	0.4	0.5	3.0	0.3	0.6	0.4	1.1	1.7	1.1	0.3	0.3	0.1	0.7	0.5	0.2	0.1	0.6
Commuting to job workplace: Public transport	0.4	0.5	1.4	0.1	0.2	-0.0	0.7	1.0	0.4	0.3	-0.9	1.1	1.0	-0.1	0.4	1.2	0.3
Arm fat-free mass (left)	0.4	2.1	8.1	-1.6	-1.3	-1.3	2.5	2.9	1.0	0.1	0.6	0.5	2.0	-1.3	1.5	0.5	-0.0
Schizophrenia vs Biploar Disorder	0.3	0.4	1.2	-0.9	-0.2	-0.3	-0.2	0.4	-0.4	-0.2	0.2	-1.1	-1.0	-0.8	-0.1	-0.1	-0.9
Major Depression (MDD)	0.3	0.4	1.5	1.2	0.1	0.9	0.1	0.6	0.6	1.0	0.1	0.1	0.3	0.7	-0.2	-1.0	0.5
Coronary Artery Disease (CAD)	0.3	0.4	2.1	-0.6	-1.5	-0.8	-0.1	0.6	-0.3	-0.6	-0.4	0.3	-0.1	-0.5	-0.8	0.5	0.1
Neuroticism (2016)	0.3	0.5	1.5	-0.2	-1.0	0.2	-0.8	-1.0	-0.4	-0.2	-1.1	-0.4	-0.6	-0.2	-1.2	-0.6	-0.4
Blood Red Count	0.3	2.4	6.0	2.0	1.6	2.4	0.8	0.3	1.4	1.6	1.6	1.0	-0.1	2.4	1.2	1.7	1.7
Supplements: Glucosamine	0.3	0.4	2.3	0.1	0.7	0.0	-0.7	-1.5	-0.6	0.2	0.9	0.5	-0.1	0.4	-0.1	0.9	0.1
Nervous feelings	0.3	0.6	2.5	-0.2	-0.7	-0.0	-1.4	-1.2	-0.8	-0.3	0.4	-0.1	-0.7	-0.3	-1.6	-0.4	-0.1
Had other major operations	0.3	0.4	1.9	-0.3	-0.4	0.0	1.1	0.5	0.6	-0.1	-0.0	0.3	0.9	-0.2	1.4	1.0	-0.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.6	1.1	0.5	0.5	-0.5	-1.1	0.0	-0.5	-1.3	-0.2	-0.2	0.6	0.0	-0.5	0.2
Qualifications: None of the above	0.3	0.6	1.7	0.7	0.7	1.2	0.3	-1.1	0.6	0.6	-1.3	0.6	0.2	0.8	0.1	0.9	0.5
Time employed in main current job	0.3	0.4	1.0	0.8	0.9	0.6	0.1	-0.2	0.5	-0.3	-0.8	-0.4	-0.5	0.7	1.0	-0.7	0.4
Falls in the last year	0.3	0.4	2.0	-0.3	-0.4	-0.4	-0.6	-0.7	-0.4	-1.4	-0.6	-0.0	0.1	-0.5	-1.2	-0.4	-0.2
Loud music exposure frequency	0.3	0.3	2.4	0.3	0.2	0.4	0.1	-0.8	0.1	-0.3	-1.5	0.2	-0.1	0.4	-0.1	0.4	0.4
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.4	0.6	0.8	0.6	-0.9	-0.8	-0.2	-0.6	1.2	0.4	-0.3	0.4	-0.5	0.4	0.4
Number of children fathered	0.3	0.4	1.8	0.5	0.1	0.3	-0.8	-1.3	-0.5	0.9	0.4	-0.2	-0.8	0.5	0.4	0.3	0.0
Age at first live birth	0.3	0.6	2.2	-1.1	-0.6	-1.5	-0.5	-0.6	-0.9	0.1	1.0	0.4	0.1	-1.2	-0.2	-0.2	-0.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.1	0.1	-0.3	-0.3	-1.0	-0.7	-0.7	-1.0	0.8	-0.4	-0.8	-0.3	-0.3	-0.3	-0.7
Emphysema/chronic bronchitis	0.3	0.3	2.5	-0.2	-0.0	-0.1	0.4	-0.6	0.1	-0.4	-1.6	-0.1	0.3	-0.0	0.6	0.5	-0.3
Suffer from ‘nerves’	0.3	0.5	2.3	0.6	0.9	1.1	-0.4	-0.2	0.2	-0.4	-0.2	-0.8	-0.4	0.7	-0.1	-1.5	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.6	0.1	-0.1	0.2	-0.2	1.0	-0.2	0.6	1.2	-0.9	-0.9	0.2	0.7	-0.6	-0.1
Knee pain experienced in last month	0.3	0.4	1.2	-0.0	0.4	0.3	0.9	0.5	0.7	0.9	0.2	0.5	1.1	0.3	-0.6	0.5	0.8
Average weekly red wine intake	0.3	0.4	1.7	-0.6	-0.9	-1.1	-0.4	0.1	-0.6	-0.3	0.5	-0.4	-0.4	-0.6	0.4	-1.3	-0.4
Asthma (self-reported)	0.3	0.6	1.8	-0.8	-0.5	-0.8	0.4	0.5	-0.1	-0.7	0.1	1.4	1.3	-0.6	-0.8	1.1	0.3
Medication: Lisinopril	0.3	0.3	1.6	-0.4	-0.8	-0.2	-0.0	0.2	0.0	0.1	-1.2	0.6	0.8	-0.4	-0.8	-0.7	0.2
Age started oral contraceptive pill	0.3	0.4	1.8	0.4	0.7	0.7	0.2	0.0	0.2	0.3	-0.3	0.5	-0.0	0.5	1.2	1.3	0.6
Commuting to job workplace: Cycle	0.3	0.4	1.8	-0.3	0.4	-0.4	-0.6	-1.3	-0.6	-0.8	-0.3	-0.6	-0.6	-0.3	-0.2	-0.7	0.1
Heart disease (siblings)	0.3	0.4	1.7	-0.1	-1.0	0.1	-0.5	-1.3	-0.2	-0.2	-0.7	-0.6	-0.7	-0.2	-0.6	-0.6	-0.2
Worry (Nagel 2018)	0.2	0.4	2.4	1.0	0.2	1.0	-0.2	0.1	0.4	1.5	-0.0	-0.2	0.1	0.6	-0.3	-0.6	0.5
LDL Cholesterol	0.2	0.3	2.0	-0.6	-0.0	-0.2	-0.3	-0.8	-0.0	1.4	0.7	-0.5	-0.3	-0.5	0.0	-0.6	-0.5
Respiratory disease	0.2	0.4	1.6	-0.1	0.2	-0.1	0.6	0.2	0.3	-0.5	0.5	1.1	1.2	-0.1	-0.1	1.0	0.6
Ever had hysterectomy (womb removed)	0.2	0.2	1.0	-0.3	-0.3	-0.4	0.7	1.0	0.1	0.4	0.9	-0.4	0.3	-0.2	0.1	-0.1	-0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	-0.8	-0.5	-0.6	-0.4	0.1	-0.5	-0.2	0.0	-0.1	-0.0	-0.8	0.2	-0.8	-0.5
Average weekly fortified wine intake	0.2	0.3	1.3	0.7	-0.4	0.5	-0.2	0.3	0.5	-0.3	-1.1	-0.1	-0.1	0.9	-0.5	-0.3	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.2	0.5	-0.5	0.7	0.4	0.7	0.5	-0.4	-1.1	-0.0	0.6	0.5	0.2	-0.8	-0.1
Worrier / anxious feelings	0.2	0.4	1.9	-0.5	-1.2	-0.3	0.0	1.4	-0.0	0.1	-0.3	-0.3	0.2	-0.6	-0.7	-0.5	-0.4
Exposure to tobacco smoke at home	0.2	0.2	0.6	-0.8	-0.4	-0.6	0.2	0.7	-0.4	-0.5	-0.4	0.0	0.1	-0.8	0.1	0.2	-0.3
Hair/balding pattern: Pattern 4	0.2	0.4	2.0	-0.4	0.5	-0.1	-0.9	-0.0	-0.9	0.5	0.1	-0.5	-1.4	-0.3	0.3	1.0	-0.4
Gout (self-reported)	0.2	0.2	1.0	-0.3	0.2	-0.2	0.4	-0.3	0.4	1.0	0.8	0.1	0.5	-0.2	0.3	-0.7	0.3
Exposure to tobacco smoke outside home	0.2	0.2	1.1	-0.7	-1.0	-0.2	0.2	1.0	-0.1	0.1	0.1	-0.3	-0.2	-0.4	0.4	-0.1	-0.4
Eye problems/disorders: None of the above	0.2	0.2	0.9	-0.3	-0.9	-0.1	0.5	0.2	0.0	-0.0	-0.8	0.4	0.2	0.0	0.7	0.9	0.2
Medication: Omeprazole	0.2	0.2	0.9	-0.6	-0.7	0.1	-0.3	-0.3	-0.2	0.0	-0.1	1.0	0.5	-0.4	-0.4	0.9	0.2
Illnesses of siblings: Diabetes	0.2	0.2	0.8	-0.2	-0.2	-0.3	0.4	0.9	0.3	-0.4	0.1	0.7	0.6	-0.2	-0.3	0.5	-0.1
Qualifications: nursing, teaching	0.2	0.3	1.0	-0.5	-0.5	-1.0	-0.4	-0.8	-0.5	-0.6	0.1	0.4	0.3	-0.8	-0.7	-0.1	-0.2
Commuting to job workplace: Walk	0.2	0.2	1.0	0.5	0.2	0.3	0.4	0.1	0.4	-0.7	-1.0	0.5	0.3	0.5	0.6	0.4	0.4
Breast cancer (self-reported)	0.2	0.3	0.8	0.2	0.5	0.2	0.9	0.4	0.9	-0.3	0.6	0.0	0.7	0.3	0.7	0.1	0.3
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.0	-0.8	-0.5	-0.0	0.0	0.1	-0.3	-0.0	0.2	0.7	0.5	-0.5	-0.2	1.0	-0.0
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	0.8	0.3	0.6	0.5	-0.2	0.7	-0.2	-0.7	0.1	0.4	0.5	0.8	-0.5	0.3
Hair Pigment	0.1	3.2	7.2	1.7	0.7	2.1	1.4	1.2	1.9	1.6	0.6	2.4	2.5	1.6	0.7	2.7	2.0
Tanning	0.1	1.5	4.0	0.1	1.3	-0.1	-1.5	-1.3	-1.0	-1.4	-1.0	-1.9	-2.0	-0.0	0.3	-1.7	-1.0
Relative age voice broke	0.1	0.2	0.7	0.2	0.6	0.0	0.8	0.3	0.6	0.5	-0.4	0.2	0.3	0.3	0.5	0.2	0.6
Stomach or abdominal pain in last month	0.1	0.2	0.8	0.1	-0.2	-0.3	0.3	0.3	0.0	0.7	0.9	-0.2	0.1	0.0	0.6	-0.6	-0.3
Depression (self-reported)	0.1	0.1	0.4	0.5	-0.6	0.3	0.0	0.5	0.3	-0.3	0.1	-0.0	0.2	0.5	0.4	-0.2	0.2
Medication: Allopurinol	0.1	0.1	0.2	-0.4	-0.3	-0.4	0.1	-0.1	-0.1	0.3	0.4	0.3	0.2	-0.5	-0.2	0.1	0.1
Family relationship satisfaction	0.1	0.1	0.5	-0.4	0.5	-0.2	-0.2	0.0	-0.2	-0.3	-0.7	-0.2	-0.2	-0.1	-0.1	-0.7	-0.4

Hub : Genes

TMEM136

Models

Trait associations