Best TWAS P=2.19e-12 · Best GWAS P=1.85e-12 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | RCSD1 | 0.13 | 0.10 | lasso | 3 | 0.09 | 1.2e-07 | 7.0 | 7.0 | 2.2e-12 | 1.00 | 0.00 | 1.00 | TRUE |
2 | GTEx | Brain Cerebellum | TADA1 | 0.23 | 0.11 | enet | 14 | 0.17 | 1.1e-05 | 5.6 | 5.5 | 4.7e-08 | -0.07 | 0.17 | 0.67 | TRUE |
3 | GTEx | Lung | RCSD1 | 0.14 | 0.05 | lasso | 7 | 0.07 | 2.4e-06 | 3.6 | 5.8 | 8.1e-09 | 0.79 | 0.02 | 0.98 | FALSE |
4 | GTEx | Whole Blood | RCSD1 | 0.09 | 0.06 | enet | 28 | 0.04 | 2.4e-04 | -4.2 | 5.9 | 3.0e-09 | 0.68 | 0.03 | 0.96 | FALSE |