[Hub]/) : Traits : Blood White Count : ← →

chr1:160,391,398-162,630,958

Best TWAS P=3.71e-20 · Best GWAS P=9.95e-18 conditioned to 5.7e-64

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
42	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HSPA7	0.23	0.13	enet	3	0.14	1.5e-06	-8.57	9.2	3.7e-20	-0.95	0.00	1.00	TRUE
15	GTEx	Nerve Tibial	PPOX	0.25	0.07	enet	43	0.15	6.7e-11	-6.52	7.1	1.5e-12	0.15	0.94	0.00	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FCRLB	0.24	0.08	bslmm	499	0.19	1.7e-22	-4.46	6.8	8.0e-12	-0.15	1.00	0.00	TRUE
5	GTEx	Adipose Subcutaneous	NDUFS2	0.06	0.09	lasso	4	0.07	2.0e-06	-5.65	6.6	3.9e-11	-0.08	0.89	0.00	TRUE
16	GTEx	Testis	ATF6	0.23	0.08	lasso	6	0.05	3.3e-03	5.87	-5.6	1.9e-08	0.12	0.21	0.05	TRUE
17	GTEx	Thyroid	PPOX	0.12	0.00	lasso	6	0.01	6.1e-02	-4.18	5.5	5.0e-08	0.00	0.04	0.04	TRUE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	HSPA7	0.04	0.02	enet	3	0.03	2.5e-06	-8.57	9.1	6.3e-20	-0.88	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	HSPA7	0.06	0.03	lasso	2	0.02	2.7e-02	-8.57	8.7	4.2e-18	-1.00	0.00	0.84	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HSPA7	0.03	0.02	lasso	1	0.01	8.7e-03	-8.57	8.6	1.0e-17	-1.00	0.00	0.84	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FCGR2C	0.04	0.03	lasso	1	0.03	2.1e-04	-8.57	-8.6	1.0e-17	1.00	0.00	0.99	FALSE
34	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HSPA7	0.02	0.02	lasso	1	0.01	1.2e-02	-8.57	8.6	1.0e-17	-1.00	0.00	0.87	FALSE
41	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	HSPA7	0.05	0.00	enet	3	0.02	2.7e-02	-8.57	8.3	1.4e-16	-0.72	0.00	0.57	FALSE
45	The Cancer Genome Atlas	Prostate Adenocarcinoma	HSPA7	0.06	0.01	enet	3	0.04	1.1e-04	-8.57	7.9	3.1e-15	-0.61	0.00	0.50	FALSE
23	NTR	Blood	FCGR2B	0.25	0.06	enet	88	0.18	7.9e-57	-8.57	-7.7	2.0e-14	0.60	0.00	1.00	FALSE
47	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FCGR3B	0.36	0.00	enet	5	0.12	4.0e-05	-8.57	-7.4	1.2e-13	0.58	0.00	0.58	FALSE
39	The Cancer Genome Atlas	Lung Adenocarcinoma	HSPA7	0.08	0.02	enet	3	0.05	9.2e-07	-0.72	7.3	2.6e-13	-0.53	0.00	0.53	FALSE
37	The Cancer Genome Atlas	Brain Lower Grade Glioma	FCRLB	0.09	0.00	blup	93	0.03	2.0e-04	-4.80	7.2	5.5e-13	-0.22	0.13	0.06	FALSE
26	YFS	Blood	FCGR2B	0.54	0.21	enet	101	0.38	9.1e-133	-5.61	-7.2	7.8e-13	0.53	0.98	0.02	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FCER1G	0.04	0.00	enet	11	0.02	4.2e-03	-6.52	6.6	5.3e-11	0.00	0.01	0.90	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	DEDD	0.02	0.03	lasso	1	0.03	4.2e-04	-6.52	6.5	7.2e-11	-0.05	0.01	0.96	FALSE
25	YFS	Blood	B4GALT3	0.04	0.02	lasso	5	0.02	7.3e-08	-5.51	6.5	7.5e-11	-0.12	0.05	0.95	FALSE
4	GTEx	Adipose Subcutaneous	B4GALT3	0.21	0.05	enet	23	0.11	1.6e-09	3.81	6.4	2.0e-10	0.01	0.90	0.01	FALSE
18	GTEx	Whole Blood	FCGR2B	0.26	0.10	enet	35	0.14	9.4e-13	-5.61	-6.3	2.4e-10	0.51	0.98	0.02	FALSE
22	METSIM	Adipose	NDUFS2	0.10	0.01	blup	393	0.05	1.3e-07	-2.68	6.3	3.1e-10	-0.19	0.96	0.00	FALSE
44	The Cancer Genome Atlas	Prostate Adenocarcinoma	FCER1G	0.10	0.07	blup	70	0.06	8.7e-07	-6.52	6.3	3.2e-10	0.01	0.00	1.00	FALSE
3	GTEx	Adipose Subcutaneous	NIT1	0.16	0.06	enet	36	0.07	1.7e-06	-6.38	6.2	4.7e-10	-0.11	0.91	0.02	FALSE
8	GTEx	Brain Hippocampus	FCRLB	0.26	0.06	lasso	4	0.06	1.3e-02	-5.41	6.2	5.4e-10	-0.12	0.07	0.20	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	FCER1G	0.06	0.02	blup	71	0.05	2.7e-06	-5.65	6.2	6.3e-10	-0.09	0.08	0.82	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	FCER1G	0.03	0.02	lasso	4	0.03	1.8e-06	-5.55	6.2	7.1e-10	-0.10	0.15	0.84	FALSE
43	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TOMM40L	0.16	0.07	lasso	3	0.05	6.0e-03	-6.13	-6.2	7.2e-10	-0.03	0.01	0.82	FALSE
11	GTEx	Cells Transformed fibroblasts	B4GALT3	0.31	0.28	enet	16	0.30	2.0e-22	3.81	5.8	4.9e-09	-0.08	1.00	0.00	FALSE
12	GTEx	Cells Transformed fibroblasts	NDUFS2	0.11	0.07	lasso	3	0.10	1.2e-07	-6.13	5.8	5.1e-09	-0.03	0.64	0.02	FALSE
24	NTR	Blood	MPZ	0.03	0.00	blup	417	0.00	4.8e-02	2.46	-5.8	6.0e-09	0.13	0.13	0.05	FALSE
19	METSIM	Adipose	B4GALT3	0.05	0.03	lasso	7	0.04	2.7e-06	-5.51	5.8	8.1e-09	-0.09	0.96	0.00	FALSE
40	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FCER1G	0.04	0.01	blup	72	0.01	7.7e-03	3.76	5.7	1.2e-08	-0.09	0.07	0.07	FALSE
9	GTEx	Breast Mammary Tissue	HSPA7	0.17	0.08	lasso	4	0.12	7.7e-07	-5.69	5.7	1.5e-08	-0.38	0.91	0.00	FALSE
10	GTEx	Breast Mammary Tissue	FCGR2C	0.15	0.13	lasso	2	0.09	2.1e-05	-5.69	5.7	1.5e-08	-0.39	0.75	0.01	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DUSP12	0.05	0.03	lasso	4	0.03	5.4e-04	-6.22	5.6	1.7e-08	-0.25	0.02	0.70	FALSE
21	METSIM	Adipose	FCGR2C	0.16	0.08	enet	27	0.10	3.3e-15	2.83	5.6	2.7e-08	-0.60	0.02	0.98	FALSE
6	GTEx	Adipose Subcutaneous	FCGR2C	0.25	0.16	lasso	5	0.14	4.1e-11	-5.69	5.5	3.6e-08	-0.39	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	PPOX	0.15	0.02	enet	34	0.03	9.4e-04	-6.13	5.5	4.8e-08	0.01	0.38	0.02	FALSE
46	The Cancer Genome Atlas	Soft Tissue Sarcoma	FCER1G	0.15	0.08	blup	70	0.09	3.3e-06	-2.68	5.4	5.8e-08	-0.05	0.02	0.97	FALSE
20	METSIM	Adipose	FCER1G	0.15	0.11	enet	15	0.12	6.3e-17	4.14	5.4	6.8e-08	-0.06	1.00	0.00	FALSE
13	GTEx	Colon Transverse	NIT1	0.17	0.10	enet	8	0.13	1.1e-06	-6.52	5.3	9.5e-08	-0.03	0.77	0.01	FALSE
7	GTEx	Artery Tibial	FCGR2C	0.17	0.03	enet	30	0.06	2.5e-05	-5.65	5.3	1.5e-07	-0.46	0.79	0.03	FALSE
14	GTEx	Muscle Skeletal	FCGR2C	0.12	0.05	lasso	4	0.04	5.2e-05	-5.69	5.2	2.2e-07	-0.38	0.40	0.04	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	NR1I3	0.03	0.04	lasso	2	0.02	9.1e-04	-5.15	5.2	2.6e-07	0.01	0.40	0.05	FALSE