Best TWAS P=7.55e-09 · Best GWAS P=1.53e-11 conditioned to 8.48e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SSPN | 0.14 | 0.07 | enet | 15 | 0.16 | 3.1e-12 | -4.8 | 5.8 | 7.5e-09 | -0.46 | 0.26 | 0.74 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | RP11-283G6.5 | 0.16 | 0.05 | enet | 14 | 0.15 | 2.2e-11 | -4.8 | 5.6 | 1.9e-08 | -0.48 | 0.62 | 0.38 | FALSE |
| 3 | GTEx | Lung | TM7SF3 | 0.19 | 0.05 | enet | 14 | 0.16 | 5.4e-12 | -4.3 | -5.4 | 7.8e-08 | -0.05 | 0.26 | 0.64 | TRUE |
| 4 | GTEx | Thyroid | TM7SF3 | 0.34 | 0.16 | enet | 36 | 0.22 | 5.1e-17 | -2.9 | -5.2 | 1.6e-07 | -0.01 | 0.73 | 0.02 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | BHLHE41 | 0.03 | 0.02 | enet | 9 | 0.02 | 2.8e-03 | -5.4 | 5.2 | 2.2e-07 | -0.72 | 0.03 | 0.73 | FALSE |