[Hub]/) : Traits : Blood White Count :

chr12:123,040,985-125,270,773

Best TWAS P=1.74e-17 · Best GWAS P=4.14e-16 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC92 0.09 0.01 bslmm 438 0.03 3.1e-04 -7.4 8.5 1.8e-17 -0.72 0.06 0.93 TRUE
2 GTEx Adipose Subcutaneous CCDC92 0.23 0.04 enet 27 0.16 6.9e-13 4.8 -5.7 1.3e-08 0.46 0.37 0.63 FALSE
3 GTEx Adipose Subcutaneous RP11-380L11.3 0.09 0.03 lasso 3 0.03 1.4e-03 -7.0 -7.9 2.4e-15 0.82 0.02 0.98 FALSE
4 GTEx Adipose Subcutaneous RP11-380L11.4 0.08 0.06 lasso 4 0.04 1.9e-04 -5.1 -5.2 2.6e-07 0.54 0.78 0.11 FALSE
5 GTEx Adipose Visceral Omentum CCDC92 0.19 0.02 lasso 8 0.09 3.3e-05 -7.1 -7.1 1.2e-12 0.57 0.13 0.83 FALSE
6 GTEx Adipose Visceral Omentum RP11-380L11.3 0.15 0.03 lasso 5 0.01 1.4e-01 -4.3 -7.5 4.9e-14 0.58 0.11 0.32 TRUE
7 GTEx Artery Tibial TMED2 0.09 0.04 enet 18 0.06 8.7e-06 5.6 6.4 1.3e-10 -0.20 0.86 0.03 TRUE
8 GTEx Artery Tibial RP11-380L11.3 0.08 0.02 lasso 2 0.01 4.5e-02 -2.1 -5.3 1.4e-07 0.72 0.01 0.92 FALSE
9 GTEx Artery Tibial RP11-380L11.4 0.14 0.12 lasso 4 0.12 2.2e-09 -7.0 -7.2 5.0e-13 0.90 0.57 0.43 FALSE
10 GTEx Brain Cerebellum GTF2H3 0.13 0.18 lasso 2 0.14 6.9e-05 5.6 -5.6 1.8e-08 0.09 0.16 0.11 TRUE
11 GTEx Brain Hypothalamus DDX55 0.37 0.05 enet 20 0.03 7.4e-02 3.4 -5.6 2.4e-08 0.35 0.09 0.14 FALSE
12 GTEx Breast Mammary Tissue (Male) CCDC92 0.06 -0.01 lasso 3 0.00 4.3e-01 -7.3 -6.6 3.6e-11 0.87 0.03 0.32 FALSE
13 GTEx Breast Mammary Tissue (Female) CCDC92 0.05 -0.01 enet 2 -0.01 6.2e-01 -7.4 -7.4 1.4e-13 0.95 0.03 0.39 FALSE
14 GTEx Colon Sigmoid RP11-380L11.4 0.21 0.12 lasso 3 0.08 1.1e-03 -7.2 -6.9 4.8e-12 0.88 0.04 0.89 FALSE
15 GTEx Esophagus Mucosa CCDC92 0.11 0.02 lasso 4 0.02 1.9e-02 -7.3 -7.3 3.5e-13 0.94 0.02 0.96 FALSE
16 GTEx Esophagus Muscularis RP11-380L11.4 0.27 0.29 lasso 8 0.27 1.0e-16 -7.1 -7.1 1.1e-12 0.91 0.62 0.38 FALSE
17 GTEx Heart Atrial Appendage CCDC92 0.12 0.11 enet 9 0.11 1.1e-05 -3.7 -6.2 6.1e-10 0.84 0.03 0.96 FALSE
18 GTEx Heart Atrial Appendage RP11-380L11.4 0.18 0.11 lasso 7 0.12 6.5e-06 -7.1 -7.0 2.1e-12 0.89 0.17 0.79 FALSE
19 GTEx Heart Left Ventricle CCDC92 0.26 0.19 lasso 4 0.21 1.9e-11 -7.3 -7.8 7.0e-15 0.91 0.33 0.67 FALSE
20 GTEx Lung CCDC92 0.14 0.00 enet 10 0.01 1.1e-01 -4.3 -5.4 6.8e-08 0.17 0.12 0.39 FALSE
21 GTEx Lung RP11-380L11.4 0.07 0.07 lasso 3 0.07 8.2e-06 -7.0 -7.4 1.5e-13 0.95 0.01 0.99 FALSE
22 GTEx Muscle Skeletal RP11-380L11.4 0.14 0.03 lasso 8 0.03 4.0e-04 -7.0 -6.7 2.3e-11 0.85 0.43 0.51 FALSE
23 GTEx Nerve Tibial CCDC92 0.16 0.01 enet 6 0.04 6.7e-04 -8.1 -6.2 6.3e-10 0.73 0.01 0.96 FALSE
24 GTEx Prostate CCDC92 0.31 0.10 enet 42 0.11 9.0e-04 -7.4 -6.3 2.9e-10 0.47 0.14 0.38 FALSE
25 GTEx Skin Sun Exposed Lower leg RP11-380L11.4 0.04 0.02 enet 15 0.02 1.9e-02 -7.1 -7.5 8.5e-14 0.77 0.04 0.91 FALSE
26 GTEx Testis RP11-380L11.3 0.14 0.05 enet 29 0.06 1.4e-03 -7.3 -5.6 2.0e-08 0.54 0.06 0.63 TRUE
27 GTEx Thyroid CCDC92 0.06 0.03 lasso 3 0.02 1.1e-02 -7.1 -6.8 1.2e-11 0.86 0.01 0.98 FALSE
28 GTEx Thyroid ZNF664 0.13 0.06 lasso 11 0.08 6.7e-07 -7.4 7.9 2.5e-15 -0.93 0.19 0.81 FALSE
29 GTEx Thyroid ATP6V0A2 0.07 0.02 enet 9 0.02 9.8e-03 4.1 5.2 1.7e-07 -0.24 0.28 0.14 FALSE
30 GTEx Whole Blood CDK2AP1 0.24 0.18 lasso 5 0.18 1.1e-16 5.5 6.6 3.4e-11 -0.13 0.25 0.75 TRUE
31 GTEx Whole Blood RP11-282O18.3 0.20 0.15 lasso 4 0.15 1.7e-13 5.5 6.3 2.9e-10 -0.11 0.26 0.74 FALSE
32 METSIM Adipose CCDC92 0.10 0.01 bslmm 435 0.06 5.5e-10 6.0 -6.8 8.4e-12 0.56 0.09 0.91 FALSE
33 METSIM Adipose DNAH10 0.03 0.00 bslmm 475 0.01 3.2e-03 -6.8 -8.1 7.4e-16 0.65 0.07 0.64 FALSE
34 METSIM Adipose RP11-214K3.24 0.05 0.03 bslmm 444 0.02 2.7e-04 -7.3 -7.0 1.9e-12 0.74 0.05 0.92 TRUE
35 YFS Blood CDK2AP1 0.26 0.27 enet 30 0.29 1.8e-96 5.5 5.2 1.7e-07 -0.06 0.27 0.73 FALSE
36 YFS Blood EIF2B1 0.13 0.12 bslmm 333 0.12 4.8e-38 5.6 5.3 1.3e-07 -0.04 1.00 0.00 FALSE
37 The Cancer Genome Atlas Glioblastoma Multiforme CCDC92 0.07 0.02 blup 52 0.04 1.8e-02 -7.4 -7.2 8.5e-13 0.94 0.02 0.70 FALSE
38 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC92 0.06 0.04 enet 8 0.05 1.7e-06 -7.3 -6.4 1.6e-10 0.78 0.14 0.80 FALSE
39 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNAH10 0.07 0.03 lasso 3 0.05 7.4e-06 -7.0 -5.7 1.6e-08 0.82 0.06 0.93 FALSE
40 The Cancer Genome Atlas Soft Tissue Sarcoma CCDC92 0.05 0.03 blup 52 0.03 5.8e-03 -6.3 -7.0 3.3e-12 0.87 0.06 0.51 TRUE
41 The Cancer Genome Atlas Thyroid Carcinoma DNAH10 0.04 0.03 lasso 5 0.02 4.6e-03 -8.1 -8.5 1.7e-17 0.96 0.00 0.95 FALSE
42 The Cancer Genome Atlas Thyroid Carcinoma ZNF664 0.06 0.05 enet 9 0.05 2.8e-05 -7.0 6.3 3.5e-10 -0.87 0.25 0.73 FALSE