[Hub]/) : Traits : Blood White Count : ← →

chr12:123,040,985-125,270,773

Best TWAS P=1.74e-17 · Best GWAS P=4.14e-16 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CCDC92	0.09	0.01	bslmm	438	0.03	3.1e-04	-7.4	8.5	1.8e-17	-0.72	0.06	0.93	TRUE
6	GTEx	Adipose Visceral Omentum	RP11-380L11.3	0.15	0.03	lasso	5	0.01	1.4e-01	-4.3	-7.5	4.9e-14	0.58	0.11	0.32	TRUE
34	METSIM	Adipose	RP11-214K3.24	0.05	0.03	bslmm	444	0.02	2.7e-04	-7.3	-7.0	1.9e-12	0.74	0.05	0.92	TRUE
40	The Cancer Genome Atlas	Soft Tissue Sarcoma	CCDC92	0.05	0.03	blup	52	0.03	5.8e-03	-6.3	-7.0	3.3e-12	0.87	0.06	0.51	TRUE
30	GTEx	Whole Blood	CDK2AP1	0.24	0.18	lasso	5	0.18	1.1e-16	5.5	6.6	3.4e-11	-0.13	0.25	0.75	TRUE
7	GTEx	Artery Tibial	TMED2	0.09	0.04	enet	18	0.06	8.7e-06	5.6	6.4	1.3e-10	-0.20	0.86	0.03	TRUE
10	GTEx	Brain Cerebellum	GTF2H3	0.13	0.18	lasso	2	0.14	6.9e-05	5.6	-5.6	1.8e-08	0.09	0.16	0.11	TRUE
26	GTEx	Testis	RP11-380L11.3	0.14	0.05	enet	29	0.06	1.4e-03	-7.3	-5.6	2.0e-08	0.54	0.06	0.63	TRUE
41	The Cancer Genome Atlas	Thyroid Carcinoma	DNAH10	0.04	0.03	lasso	5	0.02	4.6e-03	-8.1	-8.5	1.7e-17	0.96	0.00	0.95	FALSE
33	METSIM	Adipose	DNAH10	0.03	0.00	bslmm	475	0.01	3.2e-03	-6.8	-8.1	7.4e-16	0.65	0.07	0.64	FALSE
3	GTEx	Adipose Subcutaneous	RP11-380L11.3	0.09	0.03	lasso	3	0.03	1.4e-03	-7.0	-7.9	2.4e-15	0.82	0.02	0.98	FALSE
28	GTEx	Thyroid	ZNF664	0.13	0.06	lasso	11	0.08	6.7e-07	-7.4	7.9	2.5e-15	-0.93	0.19	0.81	FALSE
19	GTEx	Heart Left Ventricle	CCDC92	0.26	0.19	lasso	4	0.21	1.9e-11	-7.3	-7.8	7.0e-15	0.91	0.33	0.67	FALSE
25	GTEx	Skin Sun Exposed Lower leg	RP11-380L11.4	0.04	0.02	enet	15	0.02	1.9e-02	-7.1	-7.5	8.5e-14	0.77	0.04	0.91	FALSE
13	GTEx	Breast Mammary Tissue (Female)	CCDC92	0.05	-0.01	enet	2	-0.01	6.2e-01	-7.4	-7.4	1.4e-13	0.95	0.03	0.39	FALSE
21	GTEx	Lung	RP11-380L11.4	0.07	0.07	lasso	3	0.07	8.2e-06	-7.0	-7.4	1.5e-13	0.95	0.01	0.99	FALSE
15	GTEx	Esophagus Mucosa	CCDC92	0.11	0.02	lasso	4	0.02	1.9e-02	-7.3	-7.3	3.5e-13	0.94	0.02	0.96	FALSE
9	GTEx	Artery Tibial	RP11-380L11.4	0.14	0.12	lasso	4	0.12	2.2e-09	-7.0	-7.2	5.0e-13	0.90	0.57	0.43	FALSE
37	The Cancer Genome Atlas	Glioblastoma Multiforme	CCDC92	0.07	0.02	blup	52	0.04	1.8e-02	-7.4	-7.2	8.5e-13	0.94	0.02	0.70	FALSE
16	GTEx	Esophagus Muscularis	RP11-380L11.4	0.27	0.29	lasso	8	0.27	1.0e-16	-7.1	-7.1	1.1e-12	0.91	0.62	0.38	FALSE
5	GTEx	Adipose Visceral Omentum	CCDC92	0.19	0.02	lasso	8	0.09	3.3e-05	-7.1	-7.1	1.2e-12	0.57	0.13	0.83	FALSE
18	GTEx	Heart Atrial Appendage	RP11-380L11.4	0.18	0.11	lasso	7	0.12	6.5e-06	-7.1	-7.0	2.1e-12	0.89	0.17	0.79	FALSE
14	GTEx	Colon Sigmoid	RP11-380L11.4	0.21	0.12	lasso	3	0.08	1.1e-03	-7.2	-6.9	4.8e-12	0.88	0.04	0.89	FALSE
32	METSIM	Adipose	CCDC92	0.10	0.01	bslmm	435	0.06	5.5e-10	6.0	-6.8	8.4e-12	0.56	0.09	0.91	FALSE
27	GTEx	Thyroid	CCDC92	0.06	0.03	lasso	3	0.02	1.1e-02	-7.1	-6.8	1.2e-11	0.86	0.01	0.98	FALSE
22	GTEx	Muscle Skeletal	RP11-380L11.4	0.14	0.03	lasso	8	0.03	4.0e-04	-7.0	-6.7	2.3e-11	0.85	0.43	0.51	FALSE
12	GTEx	Breast Mammary Tissue (Male)	CCDC92	0.06	-0.01	lasso	3	0.00	4.3e-01	-7.3	-6.6	3.6e-11	0.87	0.03	0.32	FALSE
38	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC92	0.06	0.04	enet	8	0.05	1.7e-06	-7.3	-6.4	1.6e-10	0.78	0.14	0.80	FALSE
24	GTEx	Prostate	CCDC92	0.31	0.10	enet	42	0.11	9.0e-04	-7.4	-6.3	2.9e-10	0.47	0.14	0.38	FALSE
31	GTEx	Whole Blood	RP11-282O18.3	0.20	0.15	lasso	4	0.15	1.7e-13	5.5	6.3	2.9e-10	-0.11	0.26	0.74	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF664	0.06	0.05	enet	9	0.05	2.8e-05	-7.0	6.3	3.5e-10	-0.87	0.25	0.73	FALSE
17	GTEx	Heart Atrial Appendage	CCDC92	0.12	0.11	enet	9	0.11	1.1e-05	-3.7	-6.2	6.1e-10	0.84	0.03	0.96	FALSE
23	GTEx	Nerve Tibial	CCDC92	0.16	0.01	enet	6	0.04	6.7e-04	-8.1	-6.2	6.3e-10	0.73	0.01	0.96	FALSE
2	GTEx	Adipose Subcutaneous	CCDC92	0.23	0.04	enet	27	0.16	6.9e-13	4.8	-5.7	1.3e-08	0.46	0.37	0.63	FALSE
39	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNAH10	0.07	0.03	lasso	3	0.05	7.4e-06	-7.0	-5.7	1.6e-08	0.82	0.06	0.93	FALSE
11	GTEx	Brain Hypothalamus	DDX55	0.37	0.05	enet	20	0.03	7.4e-02	3.4	-5.6	2.4e-08	0.35	0.09	0.14	FALSE
20	GTEx	Lung	CCDC92	0.14	0.00	enet	10	0.01	1.1e-01	-4.3	-5.4	6.8e-08	0.17	0.12	0.39	FALSE
36	YFS	Blood	EIF2B1	0.13	0.12	bslmm	333	0.12	4.8e-38	5.6	5.3	1.3e-07	-0.04	1.00	0.00	FALSE
8	GTEx	Artery Tibial	RP11-380L11.3	0.08	0.02	lasso	2	0.01	4.5e-02	-2.1	-5.3	1.4e-07	0.72	0.01	0.92	FALSE
29	GTEx	Thyroid	ATP6V0A2	0.07	0.02	enet	9	0.02	9.8e-03	4.1	5.2	1.7e-07	-0.24	0.28	0.14	FALSE
35	YFS	Blood	CDK2AP1	0.26	0.27	enet	30	0.29	1.8e-96	5.5	5.2	1.7e-07	-0.06	0.27	0.73	FALSE
4	GTEx	Adipose Subcutaneous	RP11-380L11.4	0.08	0.06	lasso	4	0.04	1.9e-04	-5.1	-5.2	2.6e-07	0.54	0.78	0.11	FALSE