TWAS hub - VPS9D1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1940	0.0490	2.3e-09	0.146	NA	0.120	NA	0.150	5.8e-12	NA	4.7e-10	NA	2.7e-12
2	GTEx	Artery Aorta	0.1220	0.0490	1.2e-03	-0.005	NA	0.056	NA	0.007	8.0e-01	NA	5.0e-04	NA	1.3e-01
3	GTEx	Artery Coronary	0.2950	0.1110	7.1e-03	-0.008	NA	0.028	NA	0.007	8.7e-01	NA	4.1e-02	NA	1.8e-01
4	GTEx	Brain Frontal Cortex BA9	0.3469	0.1049	5.0e-04	0.205	NA	0.136	NA	0.219	3.9e-06	NA	1.9e-04	NA	1.7e-06
5	GTEx	Cells Transformed fibroblasts	0.1230	0.0440	9.6e-04	0.063	NA	0.030	NA	0.048	1.7e-05	NA	2.5e-03	NA	1.8e-04
6	GTEx	Esophagus Mucosa	0.2340	0.0640	1.9e-06	0.134	NA	0.083	NA	0.095	2.8e-09	NA	3.2e-06	NA	6.7e-07
7	GTEx	Esophagus Muscularis	0.1780	0.0670	2.4e-03	0.021	NA	0.020	NA	0.033	1.9e-02	NA	2.2e-02	NA	4.1e-03
8	GTEx	Lung	0.0646	0.0271	2.2e-03	0.077	NA	0.035	NA	0.053	1.7e-06	NA	1.1e-03	NA	6.6e-05
9	GTEx	Nerve Tibial	0.1464	0.0460	3.8e-05	0.122	NA	0.053	NA	0.097	6.0e-09	NA	1.2e-04	NA	2.2e-07
10	GTEx	Pituitary	0.3090	0.1030	6.6e-04	0.054	NA	0.142	NA	0.127	1.8e-02	NA	2.1e-04	NA	4.5e-04
11	GTEx	Prostate	0.2410	0.0940	4.1e-03	0.052	NA	0.068	NA	0.083	2.0e-02	NA	8.9e-03	NA	4.1e-03
12	GTEx	Skin Not Sun Exposed Suprapubic	0.1700	0.0520	1.0e-04	0.105	NA	0.063	NA	0.090	2.3e-06	NA	2.3e-04	NA	1.2e-05
13	GTEx	Skin Sun Exposed Lower leg	0.2420	0.0540	6.2e-11	0.134	NA	0.146	NA	0.147	3.4e-11	NA	3.8e-12	NA	3.4e-12
14	GTEx	Small Intestine Terminal Ileum	0.3360	0.0940	4.8e-04	0.039	NA	0.106	NA	0.069	4.9e-02	NA	2.4e-03	NA	1.2e-02
15	GTEx	Spleen	0.4010	0.1210	2.8e-03	0.257	NA	0.070	NA	0.205	2.8e-07	NA	7.2e-03	NA	5.6e-06
16	GTEx	Testis	0.2730	0.0750	4.5e-05	0.074	NA	0.013	NA	0.064	3.4e-04	NA	8.3e-02	NA	8.4e-04
17	GTEx	Thyroid	0.1640	0.0500	2.0e-05	0.077	NA	0.081	NA	0.087	1.7e-06	NA	8.9e-07	NA	3.7e-07
18	METSIM	Adipose	0.1659	0.0412	1.0e-13	0.138	0.1	0.118	0.136	0.132	4.8e-20	1.1e-14	3.5e-17	1e-19	3.2e-19

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Tanning	174.6	2131.6	8742.2	-35.1	-13.9	-2.4	-28.4	-20.6	-38.9	-75.1	-43.3	-45.1	-51.4	-47.2	-45.2	-66.3	-93.5	-43.6	-31.7	-19.8	-36.0
Hair Pigment	116.1	3310.3	18225.0	17.4	1.0	-13.9	12.8	27.2	29.2	113.0	33.6	36.1	80.4	54.3	51.4	75.8	135.0	71.3	13.4	3.6	28.8
Had menopause	9.2	11.5	19.5	-4.1	-4.2	-1.7	-2.9	-3.3	-4.1	-2.0	-4.4	-4.3	-2.1	-0.5	-3.6	-4.2	-1.9	-1.8	-4.3	-3.8	-4.2
Osteoarthritis (self-reported)	6.4	8.3	14.3	-3.3	0.5	-1.9	-3.8	-2.7	-2.7	-3.4	-2.6	-2.8	-2.0	-2.6	-3.0	-3.2	-3.8	-3.3	-3.2	-2.8	-2.7
Medication: Ibuprofen (e.g. Nurofen)	6.3	8.0	13.3	2.7	2.8	2.3	2.4	3.5	3.1	2.3	2.9	2.8	2.1	2.3	3.3	3.6	3.0	3.5	2.6	1.9	2.9
Alzheimer’s Disease (in mother)	5.6	6.6	17.1	-1.9	-0.8	-2.2	-2.0	-2.4	-2.2	-4.0	-2.2	-2.3	-2.7	-1.8	-2.8	-3.0	-4.1	-3.1	-2.0	-2.4	-2.4
Basal cell carcinoma (self-reported)	5.5	6.5	31.8	1.9	0.8	-1.0	1.6	-0.0	1.9	3.9	2.2	2.4	3.5	3.3	2.0	3.7	5.6	1.4	1.8	0.9	1.4
Alzheimer’s Disease (including proxy)	5.2	7.5	15.2	-2.4	-1.7	-2.4	-2.5	-2.3	-2.6	-3.8	-2.5	-2.5	-3.0	-2.1	-2.8	-3.0	-3.9	-2.9	-2.4	-3.0	-2.6
Medication: Ibuprofen	4.8	5.8	9.9	2.4	2.1	1.6	2.1	3.1	2.9	1.5	2.6	2.6	1.4	2.1	3.0	3.1	2.1	3.0	2.3	1.2	2.7
Breast Cancer	4.2	10.1	16.1	-3.5	-3.6	-1.3	-2.7	-2.9	-3.5	-3.0	-3.6	-3.5	-3.8	-1.0	-3.2	-3.6	-2.5	-2.0	-3.5	-3.7	-4.0
Age at First Birth	4.0	5.8	18.7	1.8	2.5	0.5	1.4	1.8	1.7	2.2	2.0	2.0	3.9	3.4	2.1	3.7	4.3	2.1	1.4	0.5	1.8
Alcohol drinker status: Previous	4.0	4.5	9.0	-3.0	0.1	-1.4	-2.4	-0.9	-2.2	-1.4	-2.6	-2.8	-0.3	-2.5	-2.0	-2.4	-2.4	-1.0	-3.0	-2.6	-2.0
Number of live births	3.8	5.4	14.3	-1.8	-2.6	-0.6	-1.2	-1.1	-2.1	-2.9	-2.4	-2.3	-3.0	-1.2	-1.9	-3.0	-3.8	-1.0	-2.5	-3.2	-2.4
Other serious medical condition/disability diagnosed by doctor	3.7	4.7	9.3	-2.5	-0.7	0.3	-2.4	-0.4	-2.2	-1.9	-2.1	-2.2	-3.0	-3.0	-1.5	-2.5	-2.7	-0.7	-2.9	-3.0	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	3.7	7.7	12.7	2.8	2.3	2.4	2.7	3.1	2.7	2.6	2.8	2.8	1.7	1.2	3.0	3.3	3.1	2.7	3.2	3.6	2.8
Neck or shoulder pain in last month	3.6	5.2	13.5	-2.6	-1.2	-2.2	-2.1	-2.7	-1.6	-3.2	-1.4	-1.5	-2.8	-1.4	-2.0	-2.4	-3.7	-3.0	-1.9	-1.7	-1.8
Ovarian Cancer	3.5	4.6	10.9	-1.9	-1.8	-2.1	-1.1	-2.1	-2.2	-2.0	-2.5	-2.4	-0.8	-0.6	-2.4	-2.8	-2.4	-1.7	-2.3	-2.1	-3.3
Family relationship satisfaction	3.5	4.3	9.5	1.9	2.0	1.7	0.9	2.6	1.7	2.5	1.9	1.8	2.2	1.4	2.3	2.6	3.1	2.6	1.7	1.9	1.7
Medication: Blood pressure	3.5	6.7	24.5	2.2	-0.5	0.5	3.5	0.3	2.0	4.4	1.5	1.8	2.1	2.3	1.6	2.3	4.9	1.7	2.7	4.5	1.4
HbA1C	3.4	3.8	12.6	-2.2	0.4	-1.8	-2.1	-0.5	-2.1	-2.1	-2.0	-2.1	-1.1	-3.6	-1.7	-1.7	-1.6	-1.1	-2.3	-2.6	-1.7
Comparative height size at age 10	3.3	18.4	45.8	3.5	5.5	3.4	3.7	4.1	3.4	4.0	3.5	3.5	3.1	5.0	4.0	5.6	6.8	4.1	4.1	4.5	3.6
Neuroticism (2016)	3.2	4.7	8.0	1.9	1.0	1.8	2.3	1.8	2.2	2.6	2.3	2.3	1.7	0.9	2.2	2.8	2.8	1.9	2.5	2.6	2.1
Mouth/teeth dental problems: Bleeding gums	3.2	4.2	6.8	2.3	0.3	0.9	2.0	1.9	2.1	2.4	2.1	2.1	2.1	1.5	2.4	2.5	2.4	2.6	2.4	2.1	1.3
Medication: Omeprazole	3.2	3.9	8.8	-2.5	0.4	-0.4	-2.6	-1.0	-2.3	-2.4	-2.4	-2.5	-0.3	-0.5	-2.0	-1.9	-2.0	-1.2	-3.0	-2.2	-2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.2	3.7	8.5	-1.8	-0.3	-0.9	-2.3	-1.5	-1.8	-2.3	-1.9	-2.0	-0.6	-1.2	-1.9	-2.5	-2.9	-1.8	-2.6	-2.6	-1.4
Ever used hormone-replacement therapy (HRT)	3.0	3.8	6.7	-2.4	-1.7	-0.6	-1.8	-2.2	-2.3	-1.1	-2.4	-2.4	-1.3	-1.1	-2.3	-2.6	-1.6	-1.9	-2.3	-1.4	-2.2
Bipolar Disorder (2018)	2.9	4.6	13.2	-2.0	1.3	-0.4	-3.0	0.4	-2.0	-2.5	-1.8	-2.1	-2.2	-3.6	-1.3	-2.1	-3.2	-0.7	-2.5	-2.6	-1.6
Medication: Omeprazole (e.g. Zanprol)	2.9	3.6	7.9	-1.9	0.3	-0.4	-2.6	-0.8	-2.2	-2.5	-2.3	-2.3	-0.5	-0.8	-1.9	-1.8	-2.3	-1.3	-2.8	-2.4	-1.8
Crohns Disease (2012)	2.8	4.6	7.6	2.3	1.8	2.6	2.0	2.3	2.0	1.8	1.7	1.7	2.6	2.4	2.1	2.6	2.7	2.4	1.7	1.6	1.6
Medication for cholesterol	2.8	4.2	14.8	-1.8	0.7	-0.2	-2.6	-0.5	-1.5	-3.6	-0.9	-1.2	-2.2	-2.5	-1.3	-1.7	-3.8	-1.9	-1.9	-3.1	-0.8
Osteoporosis (self-reported)	2.8	3.4	8.0	-1.1	-2.8	-1.9	-1.7	-1.9	-1.8	-1.6	-1.8	-1.8	-0.4	-1.5	-1.9	-2.3	-2.7	-1.7	-1.8	-1.6	-1.6
Blood White Count	2.6	19.3	54.6	-3.2	-3.7	-3.8	-2.9	-4.2	-3.7	-6.3	-3.3	-3.4	-5.1	-3.5	-4.4	-5.1	-7.4	-5.3	-2.7	-4.0	-4.1
Hand grip strength (left)	2.6	6.8	13.8	2.6	1.6	1.0	3.5	2.5	2.3	2.5	2.4	2.4	0.4	2.2	2.5	3.1	3.7	2.6	3.5	3.7	1.7
Medication: Ventolin 100micrograms inhaler	2.6	3.3	7.8	1.5	2.2	1.4	1.3	2.8	1.8	1.3	1.8	1.7	1.4	1.3	2.2	2.4	1.7	2.4	1.4	1.2	2.1
High blood pressure (siblings)	2.6	3.7	8.2	-1.7	-2.9	-1.3	-1.2	-2.6	-2.0	-0.2	-1.9	-1.8	-2.3	-2.8	-2.2	-1.8	-0.6	-2.2	-1.1	0.6	-2.5
Comparative body size at age 10	2.6	7.2	19.6	-3.0	-4.4	-3.9	-3.1	-2.6	-3.2	-0.8	-2.7	-2.7	-1.4	-1.0	-2.5	-2.9	-1.9	-1.6	-2.6	-2.4	-2.5
Verbal and Numeric Reasoning (VNR)	2.5	6.0	15.3	2.9	-0.6	-0.2	3.4	1.0	2.7	1.6	2.5	2.8	2.4	3.9	2.2	3.2	3.1	1.5	2.7	1.5	2.1
Supplements: Zinc	2.4	2.6	5.6	-2.2	-0.2	0.4	-1.6	-1.2	-2.2	-0.4	-2.4	-2.4	-0.6	-2.0	-1.9	-2.0	-0.8	-1.0	-1.9	0.1	-2.1
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	6.6	-2.3	-2.6	-1.0	-2.1	-2.0	-2.1	-1.5	-1.9	-2.0	-0.8	-1.0	-1.9	-2.3	-2.0	-1.7	-2.2	-2.1	-2.0
Medication: Seretide 50 evohaler	2.4	2.7	6.8	1.8	0.7	1.9	2.0	2.4	1.7	0.5	1.6	1.6	1.0	1.8	2.1	1.8	0.9	2.6	1.4	0.3	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.8	7.4	-2.1	-1.5	-1.5	-2.2	-1.4	-1.9	-0.2	-1.6	-1.7	-2.1	-2.7	-1.5	-2.2	-1.1	-1.3	-1.3	0.1	-1.8
Illnesses of siblings	2.3	3.3	8.4	2.0	2.2	1.2	2.0	1.4	2.2	0.3	1.8	1.9	2.3	2.9	1.7	1.9	1.0	1.2	1.5	0.7	2.6
Standing height	2.3	23.3	38.2	4.9	4.0	3.1	5.3	5.8	4.7	3.8	4.7	4.6	1.7	3.4	5.0	5.9	5.8	5.0	6.1	6.2	4.4
Trunk fat-free mass	2.2	12.5	27.6	3.3	2.5	1.1	3.2	4.4	3.0	3.8	3.4	3.4	0.2	2.2	4.0	4.8	5.2	4.3	4.0	3.6	3.4
Arm fat-free mass (right)	2.2	11.5	21.2	3.9	2.0	1.1	3.6	3.4	3.3	3.2	3.8	3.9	-0.3	1.8	3.7	4.5	4.2	3.1	4.6	3.7	3.6
Unable to work because of sickness or disability	2.2	2.9	6.9	-1.5	-2.0	-1.7	-1.4	-1.8	-1.4	-1.7	-1.3	-1.3	-1.8	-2.0	-1.6	-2.0	-2.6	-1.8	-1.6	-1.4	-1.1
Supplements: Calcium	2.2	2.4	13.0	-0.8	-1.1	-1.1	-0.8	-0.6	-1.0	-1.8	-1.0	-1.0	-1.9	-2.4	-1.0	-2.2	-3.6	-0.9	-1.0	-1.2	-1.4
Arm predicted mass (left)	2.2	11.3	20.1	3.5	2.5	1.1	3.3	3.9	3.1	3.4	3.6	3.5	-0.3	1.7	3.7	4.5	4.4	3.5	4.3	3.5	3.5
Intelligence (Savage-Jansen 2018)	2.1	6.4	11.9	2.9	-0.9	-0.2	3.2	2.2	2.7	1.9	2.8	2.9	2.1	3.0	2.7	3.5	3.3	2.4	2.9	1.2	2.1
Cardiovascular Disease	2.1	7.0	29.9	2.4	-2.1	-0.0	2.8	0.2	1.9	4.8	1.7	1.9	2.5	-0.7	1.6	2.2	4.2	1.4	3.0	5.5	1.3
Trunk predicted mass	2.1	11.9	26.5	3.2	2.5	1.1	3.1	4.3	2.9	3.7	3.3	3.3	0.1	2.1	3.9	4.8	5.2	4.2	3.9	3.5	3.3
Knee pain experienced in last month	2.1	3.3	6.3	-2.0	0.5	-0.7	-2.5	-0.8	-1.8	-2.2	-1.7	-1.8	-2.0	-2.1	-1.6	-2.1	-2.5	-1.4	-1.9	-1.6	-1.7
Medication: Bendroflumethiazide	2.1	3.2	11.0	1.2	0.5	1.0	1.6	1.0	1.1	2.9	1.1	1.2	1.9	0.5	1.3	2.0	3.3	1.3	1.7	3.3	1.5
Arm fat-free mass (left)	2.1	10.6	19.1	3.3	2.8	1.0	3.0	3.8	2.9	3.3	3.4	3.4	-0.2	1.6	3.6	4.4	4.3	3.5	4.0	3.4	3.4
Bipolar Disorder or Schizophrenia	2.0	4.8	14.2	-2.2	0.8	0.5	-3.2	0.9	-1.7	-2.2	-1.6	-1.8	-2.5	-3.8	-0.9	-1.9	-3.3	-0.2	-3.0	-3.1	-0.9
High blood pressure (mother)	2.0	2.8	9.3	1.1	-0.6	0.6	2.1	0.2	1.4	2.5	1.5	1.6	0.7	1.4	1.3	1.6	2.9	1.0	2.1	3.0	0.9
Fluid intelligence score	2.0	4.1	9.2	2.2	0.1	-0.6	2.4	0.9	2.2	1.7	2.2	2.4	2.1	2.7	2.0	2.8	3.0	1.4	2.0	1.5	1.7
Hair/balding pattern: Pattern 3	2.0	3.0	5.6	2.4	1.3	1.6	2.0	0.4	2.0	1.2	1.9	2.0	1.5	1.8	1.4	2.3	2.4	0.6	1.9	1.4	1.6
Qualifications: College or University degree	1.9	5.9	15.6	1.9	2.3	1.1	2.3	2.4	2.1	2.1	2.2	2.3	2.3	2.8	2.5	3.3	4.0	2.6	2.2	2.1	1.7
Hypertension (Self-reported)	1.9	5.2	24.8	1.5	-1.3	-0.2	2.1	-0.7	1.1	4.5	1.0	1.3	2.0	-0.1	0.8	1.8	4.5	0.7	2.5	5.0	0.7
Friendships satisfaction	1.9	2.4	6.5	0.9	2.1	0.5	0.5	2.5	1.3	1.9	1.2	1.2	1.9	-0.0	1.9	1.6	1.8	2.5	0.9	0.7	1.6
Medication: Lisinopril	1.9	2.4	12.2	0.6	-0.3	0.3	1.4	0.9	0.9	2.9	0.8	0.8	0.9	-0.2	1.1	2.2	3.5	1.5	1.6	2.4	0.6
Commuting to job workplace: Cycle	1.9	2.2	8.1	0.9	1.5	1.4	1.4	0.6	1.1	2.0	1.1	1.2	1.2	2.1	1.1	1.9	2.8	1.1	1.4	1.6	0.8
Stomach or abdominal pain in last month	1.8	2.2	5.6	-1.6	0.2	0.3	-1.8	-1.0	-1.3	-2.3	-1.4	-1.5	-0.9	-0.5	-1.3	-1.6	-2.4	-1.1	-2.1	-2.1	-0.9
Wears glasses or contact lenses	1.8	2.1	6.0	-1.6	-0.5	-0.7	-1.3	-1.9	-1.4	-1.5	-1.5	-1.4	-0.7	-0.4	-1.6	-1.7	-1.1	-1.6	-1.7	-2.4	-1.3
Eye problems/disorders: Glaucoma	1.8	2.1	5.0	-1.5	-0.9	-0.9	-1.5	-1.6	-1.9	-1.5	-1.6	-1.6	-0.8	-1.1	-1.9	-1.6	-1.1	-2.2	-1.3	-0.3	-1.6
Illnesses of father: High blood pressure	1.8	2.2	12.0	1.4	-1.3	-0.4	1.4	0.0	0.6	2.7	0.8	0.9	-0.7	-2.0	0.5	0.8	2.0	0.3	1.8	3.5	0.5
Number of children fathered	1.7	1.9	5.2	-1.9	0.4	1.6	-1.1	-0.1	-1.7	-1.1	-2.1	-2.1	-1.0	-0.1	-1.4	-1.3	-0.7	-0.3	-2.3	-1.2	-1.3
Arm predicted mass (right)	1.7	8.9	16.9	3.3	1.9	0.9	3.2	3.0	2.9	2.7	3.4	3.4	-0.6	1.5	3.2	4.0	3.7	2.7	4.1	3.3	3.1
Whole body fat-free mass	1.7	9.5	19.1	2.9	2.2	0.9	2.8	3.8	2.6	3.3	3.1	3.0	-0.0	1.8	3.4	4.1	4.4	3.6	3.8	3.3	3.1
Handedness (chirality/laterality): Left-handed	1.7	2.1	8.6	1.2	1.7	0.2	1.0	0.7	0.8	2.2	0.7	0.8	1.9	1.7	1.0	1.7	2.9	1.2	1.0	1.8	0.5
Basal metabolic rate	1.7	9.1	15.5	3.0	2.4	1.0	2.7	3.7	2.7	2.9	3.2	3.1	-0.0	1.6	3.4	3.9	3.8	3.3	3.9	3.3	3.2
Diastolic blood pressure, automated reading	1.7	5.2	10.6	2.7	0.0	0.5	2.8	2.2	1.9	2.9	1.8	1.9	2.6	1.5	2.1	2.6	3.3	2.6	2.7	2.3	1.8
Deep venous thrombosis (DVT) (self-reported)	1.7	2.1	6.1	-0.9	-2.2	-0.8	-0.7	-2.2	-1.0	-1.7	-0.6	-0.6	-2.5	-1.1	-1.4	-1.5	-2.2	-2.4	-0.2	-0.1	-0.5
Prostate Cancer	1.6	2.3	4.7	-2.2	-0.4	-0.4	-2.0	-1.9	-1.7	-0.5	-1.8	-1.8	-0.3	-1.8	-1.7	-1.8	-0.9	-1.5	-1.8	-0.3	-1.5
Angina	1.6	2.0	4.6	-2.1	-0.6	-0.8	-2.0	-1.2	-1.6	0.1	-1.6	-1.6	-1.3	-2.0	-1.2	-1.9	-0.9	-0.6	-1.9	-0.8	-1.4
Severe depression (siblings)	1.6	1.7	3.4	-1.4	1.1	-0.6	-1.7	-0.0	-1.5	-1.7	-1.4	-1.5	-1.4	-0.0	-1.1	-1.1	-1.5	-0.4	-1.8	-1.8	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	6.4	-1.3	-0.4	-0.5	-1.1	-0.9	-1.2	-1.7	-1.3	-1.4	-1.4	-1.7	-1.3	-1.8	-2.5	-1.1	-1.7	-1.8	-1.2
Mineral and other dietary supplements	1.6	2.1	5.1	2.1	0.1	0.1	2.0	0.6	1.8	0.3	1.9	2.0	0.6	1.4	1.2	1.7	1.1	0.2	2.3	1.3	1.9
Medication: Aspirin	1.6	2.1	10.4	0.7	-0.3	-0.7	1.1	0.5	0.9	3.2	0.9	1.0	1.3	0.7	1.2	1.3	3.0	1.6	1.1	1.9	0.9
Whole body water mass	1.6	9.3	18.7	2.9	2.2	0.8	2.7	3.7	2.6	3.2	3.1	3.0	0.0	1.8	3.4	4.1	4.3	3.5	3.8	3.3	3.1
Blood Platelet Count	1.5	17.4	28.3	4.4	1.9	2.4	4.6	3.1	4.5	4.3	4.4	4.5	5.0	3.9	4.4	5.3	4.9	3.8	4.2	3.4	4.4
Blood clot in the leg (DVT)	1.5	2.0	6.7	-0.7	-2.0	-0.9	-0.6	-2.3	-0.9	-1.7	-0.4	-0.4	-2.1	-1.1	-1.4	-1.3	-2.2	-2.6	-0.0	-0.0	-0.3
Angina (self-reported)	1.5	2.0	4.4	-2.1	-0.7	-0.8	-1.9	-1.3	-1.5	0.3	-1.5	-1.6	-1.3	-2.1	-1.2	-1.9	-0.8	-0.8	-1.8	-0.6	-1.4
Pain type(s) experienced in last month: Hip pain	1.5	1.9	3.6	-1.5	-1.2	-1.0	-1.8	-0.5	-1.3	-1.6	-1.2	-1.4	-1.5	-1.2	-1.0	-1.5	-1.9	-0.6	-1.6	-1.7	-1.3
Blood Red Count	1.4	13.5	59.3	-1.1	-2.1	-3.1	-1.6	-3.5	-1.6	-6.7	-1.4	-1.4	-3.5	-0.9	-3.1	-4.3	-7.7	-4.7	-2.0	-5.5	-2.4
Respiratory disease	1.4	3.2	9.8	0.8	2.2	2.1	1.7	3.1	1.8	1.1	1.5	1.4	1.6	-0.2	2.1	2.2	1.1	2.4	1.2	1.2	1.9
High blood pressure	1.4	3.9	18.4	1.0	-1.5	-0.3	1.7	-0.9	0.6	4.1	0.5	0.7	1.9	-0.2	0.5	1.5	4.3	0.6	1.8	4.1	0.1
Emphysema/chronic bronchitis	1.4	1.6	5.4	-0.6	1.3	0.2	-0.8	-0.8	-0.6	-1.9	-0.8	-0.9	-1.7	-2.3	-1.2	-1.2	-2.3	-1.7	-0.7	-0.2	-0.5
Ever had bowel cancer screening	1.4	1.6	4.5	-1.1	-2.1	0.3	-0.9	-0.4	-1.2	-0.4	-1.3	-1.3	-1.6	-2.1	-0.9	-1.6	-1.4	-0.1	-1.4	-1.5	-0.8
Medication: Atorvastatin	1.4	1.7	3.8	1.4	1.9	0.5	1.1	1.3	1.4	1.6	1.4	1.4	0.8	0.8	1.4	1.3	1.6	1.2	1.2	1.1	1.3
Coronary Artery Disease (CAD)	1.3	1.6	6.7	-1.5	-2.5	-0.2	-0.9	-0.5	-1.2	-0.7	-1.2	-1.1	-2.6	-0.8	-0.7	-1.4	-1.0	-0.0	-1.1	-0.5	-1.5
Past tobacco smoking	1.3	2.3	6.9	1.9	1.1	0.6	1.2	0.4	1.4	1.2	1.6	1.6	2.6	1.9	1.1	1.9	2.1	0.3	1.5	1.4	1.6
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	3.4	-1.4	-1.0	-0.4	-1.2	-1.1	-1.5	-0.6	-1.6	-1.6	-1.1	-1.8	-1.3	-1.5	-1.0	-0.6	-1.4	-0.7	-1.5
Qualifications: None of the above	1.3	2.7	9.0	-1.2	-2.5	0.4	-0.4	-1.3	-0.9	-1.3	-1.1	-1.1	-2.9	-2.0	-1.2	-2.4	-3.0	-1.3	-1.0	-1.2	-0.9
Commuting to job workplace: Car/motor vehicle	1.3	1.4	3.1	-1.2	0.0	-0.6	-1.1	-1.3	-1.3	-1.7	-1.3	-1.3	-0.2	0.1	-1.4	-1.5	-1.8	-1.3	-1.4	-1.1	-1.0
Pain experienced in last month	1.3	2.2	4.9	2.0	0.0	0.8	1.7	0.9	1.1	2.0	1.2	1.3	2.0	1.6	1.1	1.6	2.2	1.2	1.8	1.5	1.1
Crohns Disease (2017)	1.2	2.7	7.4	1.3	-0.3	0.4	1.2	2.4	1.2	2.5	1.1	1.1	2.0	0.9	1.8	1.9	2.5	2.7	1.3	1.3	1.1
Fasting Glucose	1.2	1.5	3.5	0.9	1.8	0.8	1.1	1.4	1.3	0.6	1.1	1.1	1.6	1.9	1.2	1.5	1.2	1.0	0.8	0.9	0.9
Relative age of first facial hair	1.2	2.5	15.9	-0.5	-1.9	-1.4	-0.6	-0.3	-0.6	2.9	-0.7	-0.6	0.6	1.4	0.2	1.4	4.0	1.8	-1.1	-1.5	-1.2
Had other major operations	1.2	1.4	9.4	1.2	2.4	3.1	0.5	0.8	1.1	-0.9	1.0	0.9	-0.1	0.4	0.7	0.8	-1.1	0.0	0.8	0.6	1.0
Forced vital capacity (FVC)	1.2	4.6	14.2	2.4	1.2	1.4	2.8	2.0	2.0	1.5	2.2	2.2	-0.0	0.9	1.7	2.4	2.1	1.1	3.6	3.8	2.0
Medication: Lansoprazole	1.2	1.3	3.8	-0.7	1.2	0.8	-1.1	-0.9	-0.5	-1.9	-0.6	-0.7	-1.0	-0.8	-0.9	-1.3	-2.0	-1.4	-1.1	-1.6	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.1	-1.7	-0.2	-0.9	-1.8	0.0	-1.6	-0.4	-1.8	-1.8	0.7	-1.1	-1.1	-0.8	-0.0	-0.0	-2.0	-1.2	-1.0
Average weekly champagne plus white wine intake	1.2	1.6	3.6	1.1	-0.1	-0.4	1.4	0.4	1.4	1.2	1.4	1.5	1.4	1.9	1.3	1.5	1.7	1.2	1.6	1.1	0.7
Commuting to job workplace: Public transport	1.2	1.5	4.8	0.6	-0.5	-0.2	0.7	1.4	0.7	2.1	0.7	0.8	2.2	0.5	1.2	1.5	2.2	1.6	0.7	0.8	0.5
Vascular/heart problems diagnosed by doctor	1.2	3.2	14.8	-0.9	1.8	0.7	-1.5	1.0	-0.5	-3.9	-0.3	-0.6	-1.3	0.5	-0.3	-1.1	-3.7	-0.5	-1.6	-3.8	-0.1
Height	1.1	21.9	46.2	4.9	4.5	3.6	5.5	6.1	4.2	1.9	4.6	4.4	-0.2	2.7	4.5	5.7	4.7	4.0	6.8	6.6	4.3
Medication: Metformin	1.1	1.5	3.3	1.8	1.7	1.0	1.1	0.7	1.4	0.6	1.7	1.7	-0.2	0.9	1.2	1.6	0.9	0.3	1.7	1.1	1.2
Weight	1.1	5.2	11.3	2.6	2.3	1.0	2.0	2.9	2.4	1.2	2.8	2.7	-0.8	0.4	2.6	2.5	1.4	2.0	3.4	2.5	2.9
Hip circumference	1.1	4.9	9.8	2.3	2.4	1.3	2.2	2.5	2.4	1.4	2.6	2.5	0.1	1.1	2.5	2.6	1.7	2.0	3.1	2.5	2.5
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	6.8	-1.7	1.1	-0.5	-1.7	-0.4	-1.5	-1.9	-1.4	-1.6	-1.2	-2.6	-1.5	-1.6	-1.8	-1.5	-1.3	-0.5	-1.3
Chronic bronchitis/emphysema (mother)	1.1	1.3	6.4	-1.0	2.5	1.4	-1.1	0.1	-0.9	-0.9	-1.3	-1.4	1.3	-1.0	-1.0	-0.4	-0.2	-0.7	-1.3	0.3	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.1	2.6	0.9	0.3	1.0	1.1	1.6	1.0	1.4	0.9	0.8	0.3	-0.7	1.3	0.7	0.8	1.6	1.0	1.3	1.3
Neuroticism (Nagel 2018)	1.0	2.4	9.8	0.7	-0.8	0.2	1.2	0.8	1.1	2.7	1.1	1.1	2.4	1.1	1.3	2.1	3.1	1.4	1.1	1.7	0.6
Primary Biliary Cirrhosis	1.0	1.5	3.6	-0.9	-0.7	-0.1	-0.6	-1.5	-1.2	-0.8	-1.4	-1.5	-0.8	-1.6	-1.8	-1.6	-1.2	-1.9	-0.8	0.3	-1.3
Rheumatoid Arthritis	1.0	1.3	5.0	-1.9	0.8	-0.5	-1.6	-0.6	-1.0	-0.4	-1.2	-1.4	0.2	-2.2	-1.1	-1.3	-1.1	-0.9	-1.2	0.1	-0.5
Schizophrenia (2014)	1.0	2.3	11.1	-1.4	0.8	1.0	-2.2	1.4	-0.8	-1.2	-0.7	-0.9	-1.2	-3.3	-0.2	-1.2	-2.7	0.1	-1.6	-1.7	0.3
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	5.6	0.6	1.0	0.2	-0.3	-0.3	-0.1	-1.9	0.0	0.1	-2.4	-0.7	-0.5	-0.6	-2.2	-1.1	-0.1	-1.0	-0.3
Relative age voice broke	1.0	1.5	6.6	-0.3	-2.5	-2.6	-0.6	0.5	-0.3	1.5	-0.2	-0.2	0.9	0.9	0.4	0.5	1.8	1.5	-0.7	-1.6	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.2	10.3	1.4	3.2	0.3	1.5	1.8	1.5	0.0	1.6	1.5	-0.7	1.0	1.5	1.7	0.4	1.0	1.6	1.1	1.8
Time employed in main current job	1.0	1.2	4.9	-0.0	2.2	1.7	-0.3	1.6	-0.1	0.8	-0.2	-0.2	0.9	0.9	0.6	1.1	1.7	1.7	-0.6	-0.6	0.3
Qualifications: A levels/AS levels or equivalent	1.0	2.3	8.2	1.1	2.0	0.7	1.5	1.2	1.3	2.0	1.2	1.2	1.4	1.3	1.3	2.0	2.9	1.3	1.4	1.4	0.8
Asthma	1.0	2.0	6.7	0.4	2.4	1.8	1.1	2.6	1.1	0.9	0.7	0.6	1.7	0.6	1.5	1.5	1.1	2.4	0.6	0.9	1.3
Birth weight of first child	1.0	1.7	5.5	0.2	0.6	1.4	1.0	1.6	0.9	1.8	0.7	0.8	0.7	1.3	1.4	1.5	2.3	2.2	0.8	1.2	1.1
Wheeze or whistling in the chest in last year	1.0	1.8	6.0	0.8	1.9	2.0	0.9	2.5	1.4	0.7	1.1	1.1	-1.0	-0.2	1.8	1.0	0.2	2.3	0.4	0.1	1.3
Supplements: Vitamin C	1.0	1.2	6.3	-0.9	-0.5	0.0	-0.7	0.3	-1.0	0.5	-1.1	-1.1	-2.5	-2.3	-0.5	-1.4	-1.1	0.3	-0.9	-0.7	-0.7
Commuting to job workplace: Walk	1.0	1.1	5.4	1.2	-2.3	-0.8	1.1	1.1	0.9	0.1	1.1	1.1	-0.6	0.4	1.0	0.6	-0.1	0.9	1.1	-0.4	1.4
Major Depression (MDD)	0.9	1.1	2.2	1.2	0.8	1.3	0.9	0.9	1.4	1.5	1.3	1.3	0.0	-0.1	1.3	0.4	0.4	1.2	1.2	0.9	1.2
Heel T-Score	0.9	7.4	19.7	3.6	3.0	2.9	3.5	1.3	3.0	-0.6	3.3	3.2	-0.4	1.9	1.8	3.3	1.1	-0.3	4.4	3.9	2.4
Vitamin and mineral supplements	0.9	1.2	3.2	1.5	0.4	-0.8	1.0	-0.6	1.1	-0.6	1.3	1.3	1.3	1.8	0.4	1.5	0.8	-0.8	1.6	0.9	0.8
Medication: Co-codamol	0.9	1.0	2.0	-1.4	0.6	-0.7	-1.3	-0.9	-1.2	-0.2	-1.1	-1.2	1.4	0.5	-0.9	-0.3	0.9	-0.7	-1.4	0.1	-1.4
Leg fat-free mass (left)	0.9	5.0	9.7	2.1	1.9	0.5	1.8	2.7	1.9	2.2	2.4	2.3	-0.1	1.1	2.5	2.9	2.8	2.4	3.1	2.6	2.5
Current tobacco smoking	0.9	1.4	3.2	1.2	0.5	1.8	1.7	1.0	1.5	0.3	1.5	1.5	-0.4	0.5	1.2	1.2	0.1	0.6	1.5	1.6	1.0
Qualifications: CSEs or equivalent	0.9	1.1	2.8	-0.9	-1.3	-1.7	-1.5	-1.0	-1.2	-0.8	-0.9	-1.0	0.1	-0.5	-1.2	-1.0	-1.4	-1.6	-0.6	-0.2	-0.7
Serious illness, injury or assault to yourself	0.9	1.1	4.6	-0.5	-0.7	0.1	-0.4	-0.7	-0.6	-1.1	-0.7	-0.6	-2.0	1.1	-0.5	-1.0	-1.3	-0.2	-1.4	-2.2	-0.8
Leg predicted mass (left)	0.9	5.0	9.6	2.2	1.8	0.4	1.8	2.7	1.9	2.1	2.4	2.3	-0.2	1.1	2.5	2.9	2.8	2.4	3.1	2.6	2.4
Pain all over the body in last month	0.9	1.0	2.4	-0.7	0.5	1.1	-0.9	-0.9	-0.8	-0.4	-1.2	-1.2	0.2	-1.6	-1.1	-1.5	-1.2	-1.2	-1.2	-0.0	-0.8
Breastfed as a baby	0.9	1.1	3.7	-1.0	-1.0	-1.0	-0.8	-0.9	-0.9	-1.0	-0.9	-0.9	-0.7	0.3	-0.9	-1.6	-1.6	-0.6	-1.2	-1.9	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	7.8	-0.4	-0.6	-1.3	-0.8	0.1	-0.5	-1.5	-0.4	-0.5	-1.5	-2.4	-0.5	-1.1	-2.8	-0.7	-0.5	-1.0	-0.1
Medication: Aspirin	0.9	1.2	7.0	0.3	-0.5	-0.7	0.7	0.3	0.5	2.7	0.5	0.6	1.0	0.7	0.9	0.8	2.3	1.4	0.7	1.3	0.5
Illnesses of father: Heart disease	0.9	1.3	2.4	-1.3	-1.5	-1.4	-1.3	-1.6	-1.4	-0.3	-1.2	-1.2	-0.8	-1.2	-1.2	-0.9	-0.3	-1.1	-1.1	-0.3	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.5	-1.7	0.4	-0.6	-1.4	-0.2	-1.6	-0.9	-1.9	-1.9	-0.0	-0.6	-1.1	-1.2	-0.6	0.0	-1.7	-1.4	-1.7
Hand grip strength (right)	0.8	2.2	6.3	1.5	0.2	-0.3	2.5	1.1	1.4	0.7	1.5	1.5	-1.6	1.3	1.1	1.5	1.5	0.9	2.5	2.2	0.8
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	3.5	1.1	-0.1	1.2	1.3	0.1	1.1	1.1	0.9	0.9	-0.0	1.1	0.7	0.2	0.4	0.5	1.3	1.9	0.7
Medication: Levothyroxine sodium	0.8	1.3	4.0	-1.2	1.3	-0.2	-1.5	0.1	-0.8	-1.5	-0.7	-0.9	-1.3	-2.0	-0.8	-1.0	-1.7	-1.0	-1.1	-0.6	-0.8
Sitting height	0.8	5.8	15.4	1.6	2.8	1.8	1.9	3.9	1.7	2.3	2.0	1.9	-0.2	0.9	2.7	2.9	3.4	3.4	2.6	2.5	2.0
Peak expiratory flow (PEF)	0.8	1.8	11.4	1.1	-0.0	-0.0	1.7	0.2	0.8	1.3	1.1	1.1	-0.9	0.1	0.5	1.2	1.5	-0.0	2.7	3.4	0.5
Birth weight	0.8	1.8	6.3	-2.0	-2.5	-0.0	-0.7	-0.9	-1.4	-0.7	-1.8	-1.8	-0.6	0.2	-1.2	-1.4	-0.3	-0.1	-1.5	-1.1	-1.9
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	3.6	-0.3	-1.2	-0.6	0.2	-1.4	-0.2	-1.6	-0.1	-0.1	-0.6	-1.2	-0.9	-0.9	-1.7	-1.9	0.3	0.1	-0.3
Leg fat-free mass (right)	0.8	4.3	8.9	2.0	1.2	0.2	1.6	2.4	1.7	2.2	2.3	2.2	-0.2	0.9	2.3	2.7	2.7	2.2	3.0	2.5	2.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	2.7	-1.3	-1.6	-0.4	-1.5	-0.5	-1.0	-0.7	-0.7	-0.8	-0.7	-1.1	-0.7	-1.1	-1.2	-0.5	-1.0	-1.1	-0.2
Asthma (self-reported)	0.8	1.6	5.3	0.1	2.3	1.7	1.0	2.3	0.8	0.6	0.4	0.3	1.6	0.6	1.2	1.2	0.9	2.1	0.4	0.7	0.9
Leg predicted mass (right)	0.8	4.4	9.3	2.1	1.2	0.2	1.7	2.3	1.8	2.1	2.3	2.3	-0.2	0.9	2.3	2.7	2.7	2.1	3.0	2.6	2.3
Ever taken oral contraceptive pill	0.8	0.9	4.4	1.1	1.4	0.6	0.7	0.8	1.0	0.3	0.9	0.8	2.1	0.4	0.8	1.3	0.9	0.5	0.7	0.7	0.7
Financial situation satisfaction	0.8	1.0	4.2	-0.4	-0.1	-0.9	-0.9	0.2	-0.7	-1.4	-0.8	-0.9	-1.2	-1.4	-0.5	-1.2	-2.0	0.0	-0.9	-1.5	-0.2
Ever smoked	0.8	1.4	7.0	-1.2	-1.9	-0.7	0.1	-1.1	-0.7	-0.8	-0.9	-0.9	-2.7	-1.3	-0.9	-1.3	-1.4	-0.8	-0.5	-0.2	-1.3
Depression (Nagel 2018)	0.7	1.0	3.6	0.4	-1.8	-0.8	0.6	0.4	0.6	1.8	0.7	0.7	1.9	0.4	0.8	1.0	1.5	0.8	0.6	0.9	0.5
Schizophrenia vs Biploar Disorder	0.7	1.0	2.1	0.5	-0.1	0.7	1.0	0.6	1.2	1.3	1.1	1.1	1.2	-0.6	0.9	1.1	0.9	0.4	1.0	1.4	1.5
Diabetes (father)	0.7	0.9	5.3	0.6	2.3	2.2	-0.1	1.0	0.6	-0.5	0.7	0.6	-0.9	-0.4	0.6	0.2	-0.9	0.1	0.0	-0.0	1.0
Townsend deprivation index at recruitment	0.7	1.0	4.0	-1.3	-2.0	-1.7	-1.1	-0.5	-0.5	0.0	-0.5	-0.6	-1.0	-1.6	-0.4	-1.1	-0.9	-0.2	-0.3	-0.1	-0.7
Average weekly fortified wine intake	0.7	0.8	3.9	0.1	-0.2	-0.3	0.6	0.9	0.2	1.5	0.1	0.2	1.0	1.6	0.8	0.5	2.0	1.7	-0.0	0.1	-0.2
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	3.3	-0.4	-0.6	-0.5	-0.3	-0.7	-0.5	-1.4	-0.6	-0.6	-1.3	-1.3	-0.9	-1.0	-1.8	-1.2	-0.4	-0.4	-0.6
Waist circumference	0.7	2.5	6.1	2.0	1.3	0.4	1.4	2.1	1.8	0.1	2.1	2.0	-1.3	-0.6	1.8	1.3	-0.6	1.0	2.5	1.4	2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	8.7	1.4	3.0	0.0	1.3	1.0	1.1	-0.4	1.3	1.2	-0.5	1.2	0.9	1.6	0.5	0.2	1.6	1.1	1.3
Diabetes (self-reported)	0.7	1.0	3.1	-0.7	1.0	-0.7	-1.4	-0.6	-0.7	-1.8	-0.6	-0.6	-1.1	-0.7	-0.9	-0.7	-1.3	-1.3	-1.1	-1.1	-0.5
Medication: Simvastatin	0.7	1.0	5.9	-0.4	-1.8	-0.8	-0.8	-0.9	-0.6	-0.5	-0.5	-0.5	-1.7	-2.4	-0.7	-0.9	-0.9	-0.9	-0.5	0.2	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.8	-1.2	0.2	-0.3	-1.3	-0.6	-1.0	-1.5	-1.1	-1.2	-0.6	-1.7	-1.1	-1.0	-1.4	-1.1	-1.4	-0.4	-1.0
Loud music exposure frequency	0.7	0.8	2.9	0.5	1.0	-0.2	0.7	1.1	0.9	-0.2	0.7	0.7	1.7	1.3	0.9	1.3	0.7	0.9	0.2	-0.8	0.6
Medication: Amlodipine	0.7	1.0	4.8	0.9	-1.3	-0.0	1.1	-0.4	0.2	2.1	0.1	0.3	0.1	0.3	0.3	0.5	2.2	0.8	0.9	1.7	-0.1
Forced vital capacity (FVC), Best measure	0.7	2.4	9.3	1.8	1.2	1.0	1.9	1.1	1.2	1.2	1.4	1.4	0.6	0.8	1.0	1.9	2.1	0.4	2.5	3.1	1.3
Medication: Blood pressure	0.7	1.3	6.6	-0.2	-1.0	-0.3	0.3	-1.6	-0.3	2.2	-0.2	-0.1	0.5	-0.5	-0.4	0.5	2.4	-0.5	0.7	2.6	-0.4
Leg fat mass (right)	0.7	2.9	5.9	2.0	2.4	1.1	1.5	2.1	1.9	0.1	2.2	2.1	-1.2	-0.5	1.9	1.4	-0.3	1.1	2.4	1.2	2.4
Alcohol intake frequency.	0.7	1.6	4.4	-1.7	-0.0	-0.2	-2.0	-0.6	-1.1	-1.0	-1.2	-1.4	0.1	-0.8	-1.0	-1.4	-1.8	-0.8	-2.1	-2.1	-0.6
Number of full sisters	0.7	0.9	2.9	1.0	-0.8	0.4	0.8	0.3	0.8	1.6	0.8	0.8	0.6	0.4	0.8	0.9	1.4	0.6	1.0	1.7	0.9
Chest pain or discomfort	0.7	1.0	5.6	0.7	1.8	2.4	0.2	1.1	1.0	0.7	0.8	0.8	-0.3	-0.6	0.9	0.2	-0.4	0.6	0.4	1.1	1.2
Average weekly beer plus cider intake	0.7	1.0	2.1	1.2	-0.9	0.2	1.5	0.5	1.2	1.0	0.9	1.0	1.1	0.7	0.8	1.2	1.0	0.6	1.2	1.3	0.6
Cholesterol lowering medication	0.7	1.0	4.9	-0.2	-2.2	-0.9	-0.3	-0.7	-0.7	-0.1	-0.8	-0.8	-1.5	-1.6	-0.9	-1.5	-1.0	-0.7	-0.6	-0.2	-0.8
Leg fat mass (left)	0.7	2.8	5.6	2.0	2.1	1.2	1.5	1.9	1.9	0.0	2.2	2.1	-1.4	-0.7	1.8	1.2	-0.5	0.8	2.4	1.2	2.4
Schizophrenia (2018)	0.6	1.3	3.6	-1.3	0.4	0.9	-1.7	0.9	-0.6	-0.9	-0.5	-0.7	-1.3	-1.9	-0.1	-0.7	-1.6	0.2	-1.8	-1.9	0.2
Lung FEV1/FVC ratio	0.6	3.1	7.8	-0.0	-2.8	-2.8	-0.8	-2.4	-1.3	-1.6	-1.1	-1.1	-2.1	-1.8	-1.8	-1.8	-2.2	-2.4	-0.1	-0.1	-1.7
Neuroticism	0.6	1.5	6.6	-0.1	-0.7	0.6	0.2	1.1	0.6	2.4	0.6	0.6	2.2	0.2	1.1	1.7	2.6	1.5	0.1	0.3	0.7
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.2	-0.9	-0.4	-1.5	-0.7	-0.8	-0.9	-0.4	-1.0	-1.0	0.3	-1.0	-1.1	-0.7	-0.4	-1.0	-0.8	-0.3	-0.8
Trunk fat mass	0.6	2.4	5.8	1.8	2.1	1.0	1.1	1.7	1.6	-1.0	2.0	1.8	-1.4	-1.1	1.3	0.7	-1.7	0.1	2.4	1.3	2.0
Number of incorrect matches in round	0.6	1.0	3.0	-1.0	0.6	0.3	-1.7	1.7	-1.2	-0.3	-0.9	-1.0	-0.0	-0.4	0.1	-0.2	0.1	1.6	-1.5	-1.7	0.0
Hearing difficulty/problems with background noise	0.6	0.9	5.2	-0.8	-1.3	-0.4	-0.2	-0.6	-0.6	-0.8	-0.8	-0.8	-0.9	-2.3	-0.8	-1.3	-1.5	-0.9	-0.6	0.3	-0.6
Hair/balding pattern: Pattern 2	0.6	0.8	6.8	-0.1	-1.2	-2.6	-0.3	1.2	0.1	0.6	0.4	0.3	-1.3	-0.4	0.6	0.3	0.6	1.0	0.3	-0.6	0.6
Gout (self-reported)	0.6	0.8	4.4	0.4	2.1	1.1	0.8	1.3	0.9	0.6	0.6	0.6	0.3	0.0	0.8	0.5	0.6	0.7	0.6	1.1	1.2
Worry too long after embarrassment	0.6	1.0	4.6	0.2	0.0	-0.3	0.3	-0.8	0.6	2.1	0.9	0.9	1.2	0.2	0.3	1.6	2.1	-0.6	0.6	1.0	0.8
Age at first live birth	0.6	1.0	5.3	0.2	2.0	-0.2	0.2	0.8	0.3	0.7	0.6	0.5	0.6	1.5	0.8	1.4	2.3	1.0	0.2	-0.4	0.2
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.1	-0.8	-0.9	-0.9	-1.3	0.6	-1.0	-0.5	-0.6	-0.8	-1.3	-1.4	-0.3	-0.5	-0.5	0.3	-0.8	-0.8	-0.4
Overall health rating	0.6	1.4	5.9	-1.5	0.6	0.2	-1.8	-0.1	-0.7	-0.9	-0.8	-1.0	-0.4	-2.4	-0.7	-1.2	-1.8	-0.6	-1.6	-1.1	-0.6
Had major operations	0.6	0.7	9.1	0.0	3.0	0.1	-0.7	0.3	0.1	-0.3	0.2	0.2	0.6	0.4	0.2	0.8	1.0	-0.1	-0.0	0.6	0.3
Age at last live birth	0.6	0.9	3.8	-0.7	1.2	-0.9	-1.4	-0.2	-1.2	-0.4	-0.8	-0.8	0.5	1.9	-0.3	-0.1	1.0	0.3	-1.0	-1.4	-0.8
Number of self-reported non-cancer illnesses	0.6	1.1	8.6	-1.0	-0.3	-0.5	-1.1	-0.3	-0.7	-0.4	-0.7	-0.8	-0.9	-2.9	-0.7	-1.2	-1.8	-0.7	-0.8	0.2	-0.1
Mother’s age at death	0.6	0.7	4.4	-0.2	-2.0	-0.8	0.3	-1.1	-0.4	-0.4	-0.3	-0.1	-2.1	0.2	-0.6	-0.5	-0.1	-0.8	0.1	-0.3	-0.6
Number of operations (self-reported)	0.6	0.8	4.9	-0.6	2.2	0.3	-0.9	0.2	-0.6	-1.2	-0.6	-0.7	-0.3	-1.8	-0.6	-0.0	-0.9	-0.8	-0.6	-0.1	-0.4
Myopia	0.6	0.9	5.1	-0.3	-2.3	0.2	-0.4	-0.1	-1.0	-1.0	-0.8	-0.8	-0.6	0.3	-0.5	-0.9	-1.1	0.4	-0.8	-1.7	-1.1
Heart disease (siblings)	0.6	0.7	1.6	-0.7	-0.9	-0.4	-1.3	-0.8	-1.2	0.0	-1.1	-1.0	-0.7	0.2	-0.6	-1.0	-0.2	0.2	-1.2	-1.1	-1.3
LDL Cholesterol	0.5	0.8	4.2	-1.2	0.3	-0.4	-1.1	-0.6	-0.9	-0.4	-0.8	-0.9	-0.6	-2.1	-0.9	-1.0	-0.9	-1.1	-0.7	0.7	-0.4
Medication for hormone replacement therapy	0.5	0.5	2.5	-0.6	0.5	0.1	0.1	-0.7	-0.5	0.8	-0.8	-0.7	1.6	1.1	-0.6	0.0	1.1	-0.2	-0.0	0.9	-0.6
Impedance of leg (right)	0.5	2.6	6.6	2.0	2.4	2.6	2.3	1.8	2.1	-0.2	1.4	1.4	1.5	0.6	1.3	1.2	-0.0	0.8	1.5	1.7	1.2
Trunk fat percentage	0.5	2.1	10.8	1.3	1.7	0.9	0.5	0.8	1.2	-2.1	1.4	1.2	-1.4	-1.7	0.5	-0.5	-3.3	-1.0	1.6	0.5	1.4
Maternal smoking around birth	0.5	0.7	3.6	0.3	-1.1	0.3	-0.2	-0.1	-0.2	-0.7	0.0	-0.0	-1.3	-1.5	-0.4	-0.7	-1.9	-0.8	0.6	0.9	-0.1
Fed-up feelings	0.5	0.9	6.9	-1.1	-2.6	-1.1	-1.1	-0.8	-0.6	-0.3	-0.3	-0.3	-0.6	-0.7	-0.5	-0.7	-0.6	-0.7	-0.8	-0.8	-0.3
Age when periods started (menarche)	0.5	1.1	5.0	-0.4	-1.0	-1.1	-0.5	-1.1	-0.4	-1.4	-0.2	-0.2	-2.2	-1.0	-0.9	-1.1	-1.7	-1.7	-0.3	-0.7	-0.3
Medication: Atenolol	0.5	0.6	4.3	-0.6	-2.1	-0.2	0.0	-0.7	-0.6	1.3	-0.4	-0.3	-1.1	-0.6	-0.1	-0.1	1.2	0.5	-0.1	0.3	-0.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	2.3	-1.0	-0.0	-1.5	-1.3	-0.3	-0.6	0.1	-0.7	-0.8	1.2	-1.1	-0.6	-0.3	-0.2	-0.6	-0.8	0.1	-0.2
Impedance of arm (right)	0.5	2.4	6.2	-1.7	0.5	0.3	-1.5	-0.5	-1.3	-2.1	-1.8	-1.9	1.1	-1.1	-1.5	-2.3	-2.5	-1.2	-1.7	-0.7	-1.8
Father’s age at death	0.5	0.6	3.6	-0.8	0.1	0.1	-0.3	-0.0	-0.6	-1.1	-0.5	-0.6	-1.9	-1.2	-0.6	-0.8	-1.1	-0.7	-0.5	-0.6	-0.3
Falls in the last year	0.5	0.6	1.9	-0.9	0.0	-0.5	-1.4	-0.3	-0.7	-0.6	-0.5	-0.6	-1.0	-0.5	-0.4	-0.9	-0.8	-0.4	-1.2	-1.2	-0.8
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	9.2	1.6	0.1	-0.0	1.7	0.4	0.9	0.5	1.2	1.2	-0.7	0.1	0.5	1.1	1.0	-0.3	2.6	3.0	0.8
Pulse wave Arterial Stiffness index	0.5	0.6	1.7	0.8	1.0	1.3	0.4	1.0	0.8	0.1	0.9	0.9	-0.1	-0.2	0.9	0.9	0.4	0.8	0.6	0.0	0.8
Impedance of arm (left)	0.5	2.4	11.4	-0.8	-0.4	0.4	-0.5	-1.4	-0.7	-2.7	-1.2	-1.3	0.9	-0.5	-1.6	-2.4	-3.4	-2.1	-0.8	-0.4	-1.6
Hair/balding pattern: Pattern 4	0.5	1.3	4.0	0.9	-0.6	-0.1	1.0	-1.5	0.8	1.9	0.9	1.1	1.0	1.0	0.3	1.0	2.0	-0.4	1.4	1.9	0.4
Body fat percentage	0.5	1.8	9.2	1.2	1.8	0.8	0.4	0.7	1.1	-2.0	1.3	1.1	-1.5	-1.6	0.5	-0.4	-3.0	-0.9	1.4	0.2	1.4
Health satisfaction	0.5	0.6	4.3	0.4	2.1	0.6	-0.2	1.4	0.6	0.0	0.6	0.4	0.1	-0.4	0.9	0.5	-0.2	1.0	-0.1	-0.2	1.0
Eye problems/disorders: None of the above	0.5	0.6	5.0	0.2	-1.0	1.1	0.4	-0.9	0.1	0.1	-0.0	0.1	0.7	2.2	0.1	-0.0	0.4	0.3	-0.4	-0.8	-0.5
Medication for pain relief, constipation, heartburn	0.5	0.8	3.3	0.2	-1.0	-0.1	0.1	-1.4	-0.6	-1.5	-0.4	-0.3	-1.1	0.0	-1.1	-0.8	-1.1	-1.8	0.1	-0.2	-0.6
Migraine (self-reported)	0.5	0.6	1.9	-0.3	-0.1	-0.3	-0.5	-1.1	-0.6	-1.4	-0.6	-0.6	-1.0	0.5	-0.9	-0.5	-0.7	-1.2	-0.7	-1.0	-0.4
Whole body fat mass	0.5	2.2	5.2	1.7	2.2	0.9	1.1	1.6	1.6	-0.7	2.0	1.8	-1.4	-0.9	1.4	0.8	-1.2	0.2	2.3	1.3	2.0
Illnesses of siblings: Diabetes	0.5	0.6	5.3	0.0	2.3	0.3	-0.4	1.2	0.7	0.3	0.7	0.5	0.6	-0.7	0.8	0.8	-0.1	0.6	-0.0	-0.1	0.8
Long-standing illness, disability or infirmity	0.5	0.7	2.4	-0.8	1.5	0.5	-1.1	0.2	-0.5	-0.8	-0.6	-0.6	-0.5	-0.8	-0.3	-0.9	-1.1	-0.0	-1.5	-1.3	-0.4
Diabetes diagnosed by doctor	0.5	0.9	4.4	0.1	2.1	0.1	-0.8	-0.1	-0.1	-2.0	-0.0	-0.1	-1.4	-0.4	-0.4	-0.2	-1.3	-1.0	-0.6	-1.1	-0.1
Breast cancer (self-reported)	0.5	0.6	4.7	0.5	0.1	0.6	0.1	0.2	0.2	-1.5	0.5	0.6	0.1	2.2	0.3	0.5	-0.6	-0.2	-0.1	-1.1	1.1
Illnesses of father: None of the above (group 1)	0.5	0.6	2.3	-0.7	0.0	-1.0	-0.8	-0.1	-0.5	-1.2	-0.5	-0.6	0.4	0.6	-0.4	-1.1	-1.5	-0.3	-0.7	-1.3	-0.3
Smoking status: Current	0.5	0.8	2.9	0.7	0.1	1.7	1.4	0.9	1.1	-0.2	1.1	1.1	-0.5	0.4	1.0	0.7	-0.3	0.5	1.0	1.0	0.5
Miserableness	0.5	0.9	3.6	0.7	0.4	-0.3	0.8	1.9	1.0	0.4	1.1	0.9	0.6	-0.3	1.2	1.2	0.5	1.1	1.2	0.9	1.1
Tinnitus: Yes, now most or all of the time	0.5	0.5	1.0	-1.0	0.1	0.1	-0.9	-0.8	-1.0	0.5	-0.9	-0.9	0.9	0.0	-0.9	-0.2	0.9	-0.8	-0.7	0.9	-0.1
Depressed Affect (Nagel 2018)	0.4	0.9	2.1	0.4	-0.5	-0.1	0.8	1.1	0.8	1.2	0.8	0.7	1.4	0.8	1.0	1.3	1.5	1.2	0.7	0.6	0.5
Irritable Bowel Disease (IBD)	0.4	0.9	2.8	0.1	-0.6	0.3	0.7	1.6	0.4	1.5	0.4	0.4	1.0	0.6	1.0	0.9	1.6	1.7	0.5	1.0	0.3
Reaction Time	0.4	0.7	1.8	0.9	0.2	1.3	0.4	1.2	0.7	1.2	0.8	0.8	0.0	-0.2	1.1	0.7	0.6	1.4	0.3	0.0	0.9
Mean Putamen Volume	0.4	0.4	1.9	0.1	0.3	1.2	0.1	0.7	0.1	1.1	-0.1	-0.1	1.4	0.1	0.4	0.4	1.1	0.9	-0.2	0.0	0.3
Lupus	0.4	0.6	3.1	0.7	0.7	-0.8	0.2	0.8	0.6	-0.0	0.6	0.5	-0.9	-1.8	0.7	-0.3	-1.1	0.7	0.5	0.2	1.1
Triglycerides	0.4	0.7	4.6	-0.0	0.3	0.7	-0.9	1.5	0.2	0.7	0.6	0.4	-0.1	-2.1	0.6	0.6	0.1	0.4	0.4	1.2	1.1
Number of treatments/medications taken	0.4	0.7	3.2	0.0	0.7	0.4	0.3	0.7	0.6	1.8	0.3	0.3	1.7	0.0	0.9	0.7	1.3	1.5	-0.4	0.3	0.4
Pack years adult smoking proportion	0.4	0.7	4.7	-0.1	1.6	2.2	-0.0	-0.0	0.3	-0.5	0.3	0.2	-0.6	-1.1	-0.0	-0.1	-1.3	-0.7	0.1	0.7	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	2.8	0.3	-1.7	-0.0	0.6	0.8	0.6	0.9	0.7	0.6	0.4	-0.6	0.8	0.6	0.6	0.9	0.7	0.7	0.7
Taking other prescription medications	0.4	0.6	1.8	-0.7	1.0	0.2	-1.1	1.0	-0.4	-0.4	-0.5	-0.6	0.7	-1.1	0.0	-0.4	-1.1	0.6	-1.3	-1.1	0.2
Multivitamins +/- minerals	0.4	0.5	1.8	-1.1	-0.4	1.3	-0.3	0.3	-0.6	0.7	-0.9	-0.9	-0.3	-0.6	-0.2	-0.8	0.0	0.6	-1.0	0.1	-0.5
Impedance of leg (left)	0.4	2.0	5.8	1.9	1.6	2.4	2.4	1.1	2.0	-0.7	1.4	1.4	1.2	0.2	1.0	0.8	-0.7	0.1	1.4	1.5	1.0
Mouth/teeth dental problems	0.4	0.6	1.7	-0.5	-0.7	-0.5	-0.4	-1.1	-1.0	-0.8	-0.8	-0.8	0.0	0.5	-1.1	-0.7	-0.2	-1.3	-0.8	-0.7	-0.8
Medication: Ramipril	0.4	0.5	1.4	-0.4	0.1	0.5	-0.1	-1.2	-0.6	0.5	-1.0	-0.9	-0.8	-0.6	-1.0	-0.7	0.4	-0.8	-0.4	0.9	-0.4
Mouth/teeth dental problems: Dentures	0.4	0.8	3.4	-1.0	-0.3	-0.3	-0.5	-0.6	-0.0	-0.6	-0.1	-0.2	-1.7	-1.4	-0.3	-1.1	-1.8	-0.6	-0.6	-1.0	0.2
Lung cancer (father)	0.4	0.4	3.5	0.4	-1.9	-0.5	0.9	0.5	0.3	-0.4	0.3	0.3	-1.0	0.3	0.4	-0.2	-0.4	0.6	0.9	0.4	-0.1
Leg fat percentage (right)	0.4	1.4	3.9	1.2	2.0	1.1	0.6	1.3	1.1	-0.9	1.3	1.1	-1.7	-1.4	0.9	0.1	-1.8	0.1	1.2	-0.0	1.5
Number of full brothers	0.4	0.6	5.3	0.1	2.3	0.5	-1.0	0.5	-0.0	-0.9	-0.1	-0.1	0.4	0.9	0.1	-0.1	-0.4	0.3	-0.5	-0.9	0.1
Shortness of breath walking on level ground	0.4	0.5	1.3	1.1	1.2	0.8	0.5	0.4	1.1	0.0	0.9	0.9	0.1	0.1	0.7	0.6	-0.3	0.1	0.6	0.8	0.8
Medication: Allopurinol	0.4	0.5	3.0	0.1	1.7	0.9	0.3	0.8	0.4	0.3	0.4	0.3	0.7	0.7	0.5	0.7	0.8	0.5	0.2	0.7	0.7
Leg pain on walking	0.4	0.5	3.6	-0.3	0.5	0.4	-0.5	0.2	0.4	-1.3	0.2	0.1	-0.8	-1.0	-0.0	-0.7	-1.9	-0.7	-0.1	0.1	0.5
Smoking status: Previous	0.4	0.7	2.8	-1.0	0.0	-0.2	-0.8	0.2	-0.7	0.0	-0.9	-0.9	-1.7	-1.2	-0.3	-1.0	-0.8	0.5	-0.8	-0.8	-0.5
Arm fat percentage (left)	0.4	1.7	12.2	0.1	0.7	-0.2	-0.8	-0.5	-0.1	-2.3	0.2	0.0	-1.8	-1.9	-0.5	-1.4	-3.5	-1.7	0.3	-0.8	0.2
Qualifications: nursing, teaching	0.4	0.6	3.7	0.6	1.4	-0.2	0.4	0.2	0.2	0.6	0.2	0.3	1.2	0.8	0.2	1.2	1.9	0.3	0.4	0.6	0.5
Eye problems/disorders: Cataract	0.4	0.4	3.2	0.0	-0.0	-1.8	0.4	0.5	0.3	0.4	0.2	0.1	-0.4	-1.5	0.1	0.1	0.2	-0.1	0.6	0.8	0.4
Back pain experienced in last month	0.4	0.6	4.8	-0.8	2.2	0.9	-1.2	0.6	-0.1	-0.2	-0.1	-0.2	-0.3	-0.9	0.3	0.1	-0.3	0.4	-0.8	-0.3	0.2
Hearing aid user	0.4	0.4	2.9	-0.3	1.7	0.6	0.2	0.6	-0.1	-0.2	-0.3	-0.3	0.6	0.8	0.1	0.0	0.2	0.7	-0.7	-1.1	0.1
High cholesterol (Self-reported)	0.4	0.7	1.7	0.2	-1.0	0.3	-0.6	-1.0	-0.6	-0.8	-0.7	-0.7	-1.2	-1.2	-0.8	-1.2	-1.3	-0.9	-0.7	-0.1	-0.6
Leg fat percentage (left)	0.4	1.5	5.1	1.1	1.4	1.0	0.6	0.7	1.1	-1.2	1.2	1.1	-2.1	-1.8	0.6	-0.2	-2.3	-0.4	1.1	-0.1	1.3
Irritability	0.4	0.6	3.7	-0.0	-0.8	-0.7	0.7	0.1	0.5	0.6	0.3	0.4	1.0	1.9	0.6	0.8	1.7	0.8	0.1	-0.1	-0.2
Pack years of smoking	0.4	0.6	3.7	-0.3	1.5	1.9	-0.1	-0.2	0.1	-0.7	0.1	-0.0	-0.6	-1.3	-0.2	-0.3	-1.2	-0.9	-0.1	0.6	0.4
Worry (Nagel 2018)	0.3	0.5	2.8	0.2	-1.2	0.3	0.4	0.2	0.2	1.3	0.4	0.4	0.9	-0.0	0.4	1.1	1.7	0.5	0.5	0.7	-0.1
Body Mass Index (BMI) (2010)	0.3	0.4	2.1	0.4	0.2	-0.4	0.3	0.0	0.6	1.5	0.6	0.6	0.3	0.1	0.6	0.7	1.1	0.5	0.6	0.6	0.6
HDL Cholesterol	0.3	0.5	2.0	-0.4	-0.6	-1.4	-0.0	-0.9	-0.7	-0.7	-0.8	-0.7	0.1	-0.0	-0.8	-0.6	-0.4	-0.5	-0.6	-0.8	-1.0
Ulcerative Colitis	0.3	0.5	3.1	-1.0	-0.3	1.7	0.2	-0.2	-0.4	0.3	-0.8	-0.8	0.2	0.4	-0.4	-0.5	0.4	0.2	-0.6	0.5	-0.9
Systolic Blood Pressure	0.3	1.6	9.1	-0.4	-2.5	1.0	0.3	-0.6	-0.5	3.0	-0.8	-0.7	0.5	-1.2	-0.2	-0.3	2.0	0.7	0.0	2.0	-0.7
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.9	-0.1	1.4	0.2	-0.9	0.6	-0.2	-0.9	-0.1	-0.2	-1.3	-0.8	-0.0	-0.4	-1.0	-0.1	-0.6	-0.9	-0.0
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.8	0.1	-1.4	0.0	0.2	0.4	0.2	0.9	0.3	0.3	1.2	0.2	0.3	0.4	0.8	0.2	0.4	1.1	0.6
Diabetes (mother)	0.3	0.4	1.7	-0.1	0.8	0.8	-0.9	1.0	0.0	-0.5	0.1	-0.1	0.2	-1.3	0.2	-0.2	-1.0	0.1	-0.7	-0.3	0.6
Arm fat percentage (right)	0.3	1.2	7.8	-0.1	1.4	0.1	-1.0	0.2	-0.1	-1.8	0.2	-0.0	-1.4	-1.8	-0.3	-1.1	-2.8	-1.0	0.1	-0.7	0.4
Alcohol intake versus 10 years previously	0.3	0.5	3.8	-0.9	1.9	0.8	-1.2	0.6	-0.2	-0.4	0.1	-0.1	0.3	0.3	0.2	0.4	0.2	0.2	-0.9	-0.7	0.3
Pulse rate	0.3	0.5	2.2	0.5	0.9	0.3	-0.3	-0.1	-0.2	-1.5	0.0	0.0	0.0	1.1	-0.2	-0.3	-0.9	-0.5	-0.0	-1.5	-0.4
Happiness	0.3	0.4	1.4	0.1	1.2	1.1	-0.3	0.9	0.2	-0.4	0.1	0.1	0.0	-0.0	0.5	0.4	-0.0	0.8	-0.4	-1.0	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.2	0.3	0.4	0.7	0.1	0.8	0.2	0.3	0.2	0.2	-0.3	1.1	0.6	0.6	0.7	1.1	0.1	0.1	0.2
Depression (self-reported)	0.3	0.4	1.6	-0.2	-0.9	-0.3	0.1	1.2	-0.0	-0.1	-0.1	-0.1	0.5	-0.4	0.4	0.1	-0.5	1.1	-0.3	-1.2	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	6.1	1.4	0.2	-0.3	1.1	0.0	0.5	0.7	0.8	0.8	0.5	0.4	0.2	1.2	1.5	-0.5	1.9	2.5	0.6
Exposure to tobacco smoke at home	0.3	0.3	2.0	0.4	-0.1	1.4	0.2	-0.1	0.1	-0.3	0.4	0.3	-0.4	-1.3	0.1	0.1	-0.6	-0.3	0.5	0.6	0.7
Medication: Paracetamol	0.3	0.4	2.1	-0.6	0.5	1.0	0.1	0.8	0.1	1.2	-0.3	-0.3	0.8	-0.1	0.5	-0.1	0.7	1.4	-0.7	0.2	-0.1
Exposure to tobacco smoke outside home	0.3	0.4	2.6	0.5	-0.4	0.3	-0.2	0.6	0.2	-0.6	0.4	0.3	-0.6	-1.6	0.1	0.2	-1.1	-0.4	0.4	-0.1	0.5
Mood swings	0.3	0.6	1.7	-1.2	-0.4	0.6	-0.6	1.2	-0.7	-0.6	-0.7	-0.8	-0.5	-0.7	-0.1	-0.3	-0.3	0.7	-1.0	-1.3	-0.2
Medication: Gliclazide	0.3	0.4	3.4	0.4	1.8	0.7	0.3	0.6	0.7	-0.1	0.6	0.6	0.2	-0.3	0.5	0.4	-0.3	0.2	0.3	-0.1	0.7
Guilty feelings	0.3	0.5	4.4	-0.2	0.0	0.2	0.2	-0.3	0.2	1.0	0.1	0.1	2.1	0.4	0.0	0.6	1.4	-0.2	0.1	0.7	0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.2	-0.9	0.1	0.2	-0.7	0.5	-0.4	1.1	-0.5	-0.6	-0.1	-0.8	0.1	-0.2	0.6	0.9	-0.9	-0.2	-0.3
Alcohol drinker status: Never	0.3	0.3	2.0	0.5	-1.4	0.0	0.4	-0.8	0.1	-0.4	-0.1	-0.0	-0.7	0.8	-0.4	-0.6	-0.7	-0.6	0.1	-0.5	-0.1
Risk taking	0.3	0.4	1.8	-0.2	-0.1	-0.5	-0.6	0.1	-0.4	-0.8	-0.5	-0.5	1.4	1.0	-0.3	-0.1	-0.4	0.1	-0.8	-1.1	-0.1
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.8	-0.8	0.1	0.4	-0.5	-0.9	-0.5	-0.4	-0.6	-0.6	0.8	-0.3	-0.6	-0.1	0.4	-0.7	-0.9	-0.3	-0.7
Age started oral contraceptive pill	0.3	0.3	1.8	-0.0	-1.0	-1.3	-0.1	-1.1	-0.3	-0.2	-0.2	-0.2	0.5	-0.2	-0.6	-0.1	-0.0	-0.8	-0.0	-0.5	-0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.6	0.1	1.2	0.9	-0.7	0.8	-0.1	0.8	-0.0	-0.1	-0.2	0.3	0.4	0.3	0.7	0.9	-0.1	0.4	0.5
Alzheimer’s Disease (in father)	0.2	0.3	1.3	-0.5	-1.1	-0.4	-0.4	0.1	-0.4	-0.6	-0.2	-0.3	-0.7	-0.6	-0.1	-0.1	-0.4	0.1	-0.6	-0.8	0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.3	1.4	0.8	0.6	0.5	-0.3	0.1	0.2	-0.8	0.2	0.2	-0.1	-0.7	-0.1	-0.2	-1.2	-0.7	0.3	0.7	0.3
Blood Eosinophil Count	0.2	1.3	3.2	1.2	0.5	1.2	1.0	1.2	1.5	0.5	1.3	1.3	1.8	0.0	1.4	1.5	0.4	1.1	0.7	0.1	1.5
BMI	0.2	1.2	2.4	1.2	1.5	-0.6	-0.3	1.3	0.8	-0.6	1.4	1.3	-1.2	-1.6	1.0	0.6	-1.4	0.2	1.2	-0.5	1.5
Waist Hip Ratio (WHR)	0.2	1.1	3.9	0.7	-1.7	-0.5	0.8	1.3	0.5	-0.9	0.6	0.6	-1.9	-1.8	0.6	-0.3	-2.0	0.5	0.8	-0.1	0.4
Smoking Status	0.2	0.6	3.7	-0.7	-0.9	0.6	0.3	0.9	0.2	-0.1	0.1	0.0	-1.9	-1.3	0.5	-0.5	-1.2	0.8	0.0	0.0	0.3
Hypothyroidism (self reported)	0.2	0.5	3.8	-0.3	1.0	-0.2	-0.7	0.9	-0.1	-0.7	0.1	-0.1	-1.0	-1.9	0.0	-0.0	-0.8	-0.1	0.0	0.3	0.3
Average weekly spirits intake	0.2	0.2	1.2	-0.3	-1.1	-0.5	0.5	-0.8	-0.1	0.5	-0.2	-0.1	-0.2	0.3	-0.3	-0.4	0.3	-0.2	0.3	0.5	-0.8
Sensitivity / hurt feelings	0.2	0.4	1.9	-0.2	-0.2	0.4	-0.1	-0.0	-0.2	1.4	0.1	0.1	0.1	-0.9	0.1	0.7	1.3	-0.0	0.1	1.0	0.3
Hearing difficulty/problems: Yes	0.2	0.4	1.3	0.3	0.9	0.3	0.9	0.2	0.9	-0.3	0.6	0.6	0.2	-0.4	0.3	0.2	-0.6	-0.4	0.4	1.2	0.9
Ever had hysterectomy (womb removed)	0.2	0.2	0.7	-0.3	-0.3	0.8	-0.2	0.6	-0.4	0.3	-0.7	-0.6	-0.3	-0.5	-0.1	-0.4	-0.3	0.8	-0.8	-0.4	-0.3
Systolic blood pressure, automated reading	0.2	0.5	2.8	-0.1	-1.7	-0.2	-0.4	-0.1	-1.0	0.8	-1.0	-0.9	-0.3	-0.5	-0.5	-0.7	0.1	0.5	-0.6	-0.6	-0.7
Supplements: Glucosamine	0.2	0.3	1.6	-0.3	0.1	0.5	-0.3	0.3	-0.4	0.6	-0.5	-0.5	1.3	0.3	-0.0	-0.2	-0.0	0.7	-0.6	-0.5	-0.5
Chronic bronchitis/emphysema (father)	0.2	0.2	1.9	-0.4	-1.4	-0.1	0.2	-0.0	0.1	-0.3	-0.1	-0.1	0.4	1.0	-0.1	-0.4	-0.6	0.0	-0.2	-0.7	-0.5
Nervous feelings	0.2	0.3	1.7	-0.3	0.5	0.5	-0.1	0.3	-0.0	1.2	-0.1	-0.1	0.8	-0.4	0.2	0.7	1.3	0.6	-0.1	0.2	-0.2
Financial difficulties in last 2 years	0.2	0.2	1.1	-0.0	-1.0	-0.4	-0.2	-0.6	-0.0	-0.5	-0.2	-0.1	0.0	-0.2	-0.3	-0.6	-1.0	-0.5	-0.3	-0.6	-0.0
Heart attack	0.2	0.3	1.0	0.0	1.0	0.7	-0.7	0.7	-0.3	0.6	-0.2	-0.2	-0.4	0.4	0.3	0.1	0.6	0.8	-0.2	0.1	0.4
Allergy	0.2	0.4	1.5	-0.2	-1.1	-0.7	-0.1	-0.8	-0.6	0.2	-0.6	-0.5	-1.2	0.5	-0.6	-0.4	0.6	-0.3	-0.4	-0.6	-1.0
Neuroticism score	0.2	0.5	2.8	-0.2	-0.7	0.3	0.2	0.3	0.3	1.4	0.5	0.5	1.2	0.1	0.5	1.0	1.7	0.4	0.3	0.6	0.2
Noisy workplace	0.2	0.3	1.2	0.1	-0.2	0.6	0.3	0.6	0.2	1.0	0.0	0.0	-1.0	-1.1	0.4	0.0	0.2	0.9	-0.1	-0.1	0.2
Illnesses of mother	0.2	0.3	1.5	-0.0	0.6	-0.2	-0.3	0.8	-0.1	-0.3	-0.1	-0.2	-0.7	-1.1	0.1	-0.3	-0.7	0.3	-0.4	-1.2	0.1
Arm fat mass (right)	0.2	1.0	3.1	0.9	1.8	0.3	0.2	1.3	0.8	-0.5	1.2	1.1	-1.4	-1.0	0.9	0.4	-1.1	0.2	1.4	0.5	1.3
Length of working week for main job	0.2	0.3	1.3	-0.0	0.4	-0.7	0.2	-0.5	0.1	-0.6	0.3	0.3	1.2	0.4	-0.3	0.3	-0.2	-1.0	0.4	0.1	0.4
Tense / ‘highly strung’	0.2	0.3	2.0	0.1	-1.4	0.4	-0.1	0.6	-0.3	0.5	0.1	0.0	-0.7	-1.2	0.2	0.0	0.1	0.6	0.3	0.3	0.1
Pulse wave reflection index	0.2	0.3	0.8	0.1	-0.0	0.4	0.7	0.0	0.5	0.8	0.4	0.4	-0.8	-0.5	0.4	0.7	0.9	0.5	0.4	0.7	0.3
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.9	0.4	-0.5	-0.8	-0.3	0.5	0.2	0.6	0.3	0.2	0.1	-0.9	0.4	0.2	-0.2	0.6	0.2	0.2	-0.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.4	-0.3	1.0	-0.6	-0.7	-0.0	-0.6	-0.0	-0.6	-0.6	1.2	0.3	-0.6	0.1	0.6	-0.4	-0.3	0.2	-0.7
Headache pain in last month	0.2	0.3	1.0	-0.9	-1.0	-0.7	-0.0	-0.7	-0.1	-0.3	-0.4	-0.3	-0.3	0.5	-0.2	-0.3	-0.1	-0.1	-1.0	-1.0	-0.5
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.9	0.2	-0.3	0.1	0.1	1.4	0.1	-0.5	0.1	0.0	-0.7	-0.1	0.4	-0.1	-0.8	0.8	0.1	-0.9	0.3
Glaucoma (self-reported)	0.2	0.3	1.4	-0.1	-0.4	-0.4	-0.4	-0.4	-0.6	-1.1	-0.2	-0.3	-0.6	-0.0	-0.6	-0.5	-0.6	-1.2	-0.1	0.0	-0.3
Pulse wave peak to peak time	0.2	0.2	1.0	-0.4	-0.5	-1.0	-0.1	-0.6	-0.5	0.1	-0.6	-0.5	0.3	0.5	-0.6	-0.5	0.0	-0.5	-0.1	0.4	-0.5
Suffer from ‘nerves’	0.2	0.4	2.9	0.1	-1.7	0.4	0.7	0.1	0.4	1.1	0.4	0.4	0.4	0.1	0.5	0.3	0.4	0.8	0.4	-0.0	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.6	0.6	0.8	0.1	0.3	0.5	0.4	0.4	0.5	0.5	-0.3	0.2	0.5	0.7	0.1	0.4	0.4	0.3	0.8
Loneliness, isolation	0.2	0.3	1.4	-0.2	-0.9	-0.6	-0.0	-0.3	0.1	1.2	0.3	0.3	0.4	0.3	0.1	0.4	1.1	-0.2	0.5	1.1	-0.1
Arm fat mass (left)	0.2	0.9	2.4	0.9	1.5	0.2	0.1	0.8	0.7	-0.8	1.2	1.0	-1.6	-1.1	0.7	0.2	-1.4	-0.3	1.4	0.5	1.2
Medication: Paracetamol	0.2	0.3	0.9	-0.9	-0.2	0.5	-0.1	0.5	0.0	0.8	-0.4	-0.4	-0.4	-0.6	0.3	-0.5	-0.0	1.0	-0.8	-0.2	-0.3
Impedance of whole body	0.2	1.0	6.7	0.2	0.5	1.2	0.7	-0.3	0.4	-2.0	-0.2	-0.2	1.0	-0.5	-0.6	-1.2	-2.6	-1.3	0.1	0.5	-0.5
Ulcerative Colitis (UC)	0.1	0.1	0.7	-0.7	-0.8	0.3	0.2	0.0	-0.3	-0.3	-0.4	-0.4	-0.2	-0.0	-0.4	-0.3	-0.2	-0.2	-0.4	0.1	-0.5
Allergy or Eczema	0.1	0.3	2.7	-0.6	0.4	-0.2	-0.8	0.4	-0.1	-0.3	-0.2	-0.2	1.6	-0.3	0.2	-0.1	-0.4	0.4	-0.4	-0.5	0.4
Lung FVC	0.1	0.7	2.8	1.0	-0.2	1.7	1.3	-0.1	0.4	-0.4	0.5	0.6	-1.3	0.3	-0.0	0.0	-0.2	-0.6	1.2	1.3	0.7
Chronotype (morning person)	0.1	0.2	0.9	-0.9	-1.0	0.2	-0.4	0.1	-0.6	0.3	-0.4	-0.4	-0.1	-0.8	-0.2	-0.1	0.1	0.0	-0.5	-0.3	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.9	-0.7	-0.1	-0.8	-0.8	-0.3	-0.4	-0.5	-0.5	-0.5	1.4	-0.1	-0.3	-0.4	-0.5	-0.2	-0.6	-0.3	-0.1
Body mass index (BMI)	0.1	0.6	2.9	0.4	0.6	-0.4	-0.4	0.4	0.3	-0.6	0.8	0.7	-1.7	-1.3	0.4	-0.1	-1.4	-0.2	0.6	-0.4	0.9
Alcohol usually taken with meals	0.1	0.1	1.3	-0.5	0.4	-1.1	-0.3	-0.1	-0.2	0.3	-0.1	-0.1	0.6	-0.3	-0.0	-0.2	0.3	0.0	-0.2	0.1	0.1
Worrier / anxious feelings	0.1	0.2	0.5	-0.5	-0.4	0.5	-0.2	-0.6	-0.3	-0.3	-0.1	-0.1	-0.0	0.4	-0.4	0.4	0.7	-0.7	-0.1	0.3	-0.1
Medication: Cholesterol lowering	0.1	0.2	1.2	0.6	1.1	0.3	-0.2	-0.6	0.4	-0.1	0.5	0.6	0.6	0.3	0.2	0.3	0.1	-0.4	-0.1	0.0	0.3
Prospective memory result	0.1	0.1	1.0	-0.3	-0.2	-1.0	-0.1	-0.3	-0.2	0.3	-0.3	-0.3	0.2	0.0	-0.3	-0.2	-0.1	-0.2	0.0	0.2	-0.5
Mean time to correctly identify matches	0.1	0.3	1.4	0.0	-0.7	1.2	-0.0	0.5	-0.1	0.6	-0.2	-0.2	-0.5	0.2	0.3	-0.2	0.1	1.0	-0.7	-0.5	0.1
Heart disease (mother)	0.1	0.1	1.1	0.2	-0.5	0.3	0.0	-0.5	-0.0	0.7	-0.1	0.0	-0.1	0.2	-0.1	-0.1	0.4	-0.1	0.2	1.0	0.0
Pulse rate, automated reading	0.1	0.4	1.6	0.0	-0.1	-0.3	-0.3	-0.7	-0.3	-1.0	-0.2	-0.1	-0.4	-0.6	-0.5	-0.6	-1.3	-0.8	-0.4	-1.2	-0.2
Average weekly red wine intake	0.1	0.1	0.5	-0.6	-0.1	-0.7	-0.0	0.0	-0.1	-0.4	-0.2	-0.3	-0.3	-0.5	-0.1	-0.4	-0.5	0.1	-0.4	-0.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.7	0.7	0.8	0.2	0.1	0.0	0.2	0.5	0.3	0.3	-0.3	-0.2	-0.0	0.0	-0.2	-0.4	0.8	1.3	0.6
Fractured/broken bones in last 5 years	0.1	0.2	0.7	-0.2	0.0	0.9	-0.1	0.7	-0.3	-0.2	-0.2	-0.2	-0.4	-0.1	0.2	-0.1	0.2	0.8	-0.5	-0.8	-0.5
Ever depressed for a whole week	0.1	0.1	0.7	0.3	0.1	0.2	0.2	0.7	0.3	0.6	0.2	0.2	0.0	-0.3	0.5	0.1	0.0	0.9	0.2	-0.1	0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

VPS9D1

Models

Trait associations