[Hub]/) : Traits : Blood White Count : ← →

chr18:19,692,435-22,415,141

Best TWAS P=2.39e-11 · Best GWAS P=1.27e-14 conditioned to 1.46e-10

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	YFS	Blood	TTC39C	0.27	0.20	bslmm	511	0.21	4.6e-66	6.7	6.7	2.4e-11	-0.04	0.00	1.00	TRUE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	C18orf8	0.07	0.05	lasso	5	0.03	9.5e-05	-5.7	5.8	7.7e-09	-0.14	0.00	1.00	TRUE
6	GTEx	Testis	RBBP8	0.20	0.12	lasso	3	0.08	2.2e-04	5.1	5.1	2.9e-07	-0.06	0.76	0.01	TRUE
3	GTEx	Artery Tibial	C18orf8	0.18	0.12	lasso	3	0.10	1.5e-08	-5.7	5.7	1.3e-08	-0.15	1.00	0.00	FALSE
7	GTEx	Testis	C18orf8	0.12	0.07	lasso	6	0.08	1.9e-04	4.3	5.7	1.6e-08	-0.23	0.30	0.06	FALSE
10	The Cancer Genome Atlas	Esophageal Carcinoma	NPC1	0.16	0.10	lasso	3	0.10	3.7e-04	-5.7	5.6	2.8e-08	-0.14	0.01	0.93	FALSE
5	GTEx	Nerve Tibial	NPC1	0.19	0.12	lasso	6	0.16	1.1e-11	-5.7	5.5	3.2e-08	-0.14	1.00	0.00	FALSE
4	GTEx	Esophagus Muscularis	C18orf8	0.14	0.13	lasso	3	0.10	8.0e-07	-5.7	5.5	3.9e-08	-0.16	0.96	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	NPC1	0.08	0.07	lasso	3	0.08	5.2e-10	-5.7	5.4	6.4e-08	-0.12	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C18orf8	0.26	0.35	lasso	6	0.40	1.9e-52	4.3	5.3	9.7e-08	-0.15	1.00	0.00	FALSE
9	The Cancer Genome Atlas	Breast Invasive Carcinoma	NPC1	0.03	0.03	blup	69	0.04	2.9e-09	4.2	5.3	1.0e-07	-0.14	0.05	0.95	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	NPC1	0.07	0.08	lasso	3	0.10	1.6e-11	-5.7	5.1	3.0e-07	-0.16	0.01	0.99	FALSE