TWAS hub - C18orf8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2650	0.0410	0.0e+00	0.351	0.337	0.401	0.378	0.402	2.0e-44	2.9e-42	3.4e-52	1.4e-48	1.9e-52
2	GTEx	Adipose Subcutaneous	0.1680	0.0390	1.6e-10	0.155	NA	0.163	NA	0.159	1.1e-12	NA	2.6e-13	NA	5.2e-13
3	GTEx	Adipose Visceral Omentum	0.1770	0.0650	1.2e-04	0.106	NA	0.038	NA	0.001	3.8e-06	NA	4.5e-03	NA	2.8e-01
4	GTEx	Artery Tibial	0.1786	0.0557	8.2e-05	0.115	NA	0.091	NA	0.104	2.6e-09	NA	1.3e-07	NA	1.5e-08
5	GTEx	Brain Caudate basal ganglia	0.1460	0.0640	2.5e-03	0.163	NA	0.106	NA	0.050	2.0e-05	NA	5.9e-04	NA	1.5e-02
6	GTEx	Brain Cerebellar Hemisphere	0.2750	0.0800	2.2e-05	0.345	NA	0.343	NA	0.327	1.0e-09	NA	1.3e-09	NA	3.6e-09
7	GTEx	Brain Cerebellum	0.2310	0.0710	2.3e-05	0.182	NA	0.206	NA	0.136	4.7e-06	NA	9.9e-07	NA	8.2e-05
8	GTEx	Brain Cortex	0.1940	0.0740	9.0e-04	0.181	NA	0.082	NA	0.131	1.0e-05	NA	2.8e-03	NA	1.8e-04
9	GTEx	Brain Frontal Cortex BA9	0.4189	0.0945	5.1e-08	0.297	NA	0.082	NA	0.007	1.4e-08	NA	3.4e-03	NA	2.1e-01
10	GTEx	Esophagus Muscularis	0.1360	0.0520	8.3e-04	0.128	NA	0.095	NA	0.103	3.8e-08	NA	2.2e-06	NA	8.0e-07
11	GTEx	Nerve Tibial	0.1615	0.0477	4.8e-06	0.074	NA	0.093	NA	0.068	6.5e-06	NA	3.9e-07	NA	1.6e-05
12	GTEx	Skin Not Sun Exposed Suprapubic	0.2110	0.0530	1.8e-08	0.267	NA	0.231	NA	0.047	6.8e-15	NA	6.9e-13	NA	1.3e-03
13	GTEx	Skin Sun Exposed Lower leg	0.3460	0.0520	0.0e+00	0.327	NA	0.355	NA	0.295	9.4e-28	NA	1.7e-30	NA	9.3e-25
14	GTEx	Testis	0.1180	0.0510	2.4e-03	0.069	NA	0.077	NA	0.081	5.6e-04	NA	2.6e-04	NA	1.9e-04
15	METSIM	Adipose	0.0782	0.0309	9.8e-05	0.023	0.025	0.040	0.028	0.031	1.8e-04	8.5e-05	1.0e-06	4.4e-05	1.6e-05
16	TCGA	Brain Lower Grade Glioma	0.0693	0.0405	1.9e-05	0.047	0.025	0.026	NA	0.034	4.6e-06	6.9e-04	5.1e-04	NA	9.5e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Average weekly red wine intake	31.6	46.6	60.1	7.4	7.0	5.6	7.6	7.1	6.6	6.6	6.1	5.7	7.8	7.5	6.2	6.8	6.9	6.1	7.6
Alcohol intake frequency.	29.5	68.6	79.3	-8.9	-8.8	-6.8	-8.1	-8.8	-8.6	-8.7	-8.2	-8.0	-8.6	-8.4	-8.3	-8.3	-8.7	-6.5	-8.3
Whole body fat mass	19.8	82.7	103.9	-9.6	-9.7	-8.8	-7.9	-9.6	-9.6	-9.6	-9.5	-8.7	-8.9	-9.0	-9.4	-9.6	-10.2	-6.6	-8.1
Leg fat mass (right)	19.7	76.2	93.6	-9.3	-9.4	-8.0	-7.6	-9.3	-9.3	-9.3	-9.2	-8.5	-8.5	-8.6	-9.1	-9.1	-9.7	-6.2	-7.8
Waist circumference	19.6	71.7	95.9	-8.9	-9.1	-8.3	-7.2	-8.9	-9.0	-9.0	-8.9	-8.3	-8.2	-8.1	-8.9	-8.8	-9.8	-6.3	-7.4
Leg fat mass (left)	19.0	74.0	90.0	-9.1	-9.3	-8.0	-7.5	-9.2	-9.2	-9.1	-9.1	-8.5	-8.3	-8.6	-9.0	-9.0	-9.5	-5.9	-7.6
Weight	18.8	92.3	134.6	-10.0	-10.2	-9.5	-8.3	-10.0	-10.1	-10.2	-9.8	-9.1	-9.3	-9.0	-9.8	-9.9	-11.6	-7.8	-8.4
Trunk fat mass	18.5	79.6	102.0	-9.4	-9.5	-8.6	-8.0	-9.4	-9.4	-9.3	-9.2	-8.3	-8.9	-8.8	-9.1	-9.3	-10.1	-6.8	-8.1
BMI	17.7	102.4	124.8	-10.9	-11.0	-9.4	-9.0	-10.9	-10.9	-10.4	-10.6	-10.1	-10.0	-11.2	-10.7	-10.8	-9.8	-5.6	-9.3
Arm fat mass (right)	17.2	70.8	82.3	-8.9	-9.0	-8.1	-7.3	-9.0	-9.0	-8.8	-8.8	-8.2	-8.2	-8.7	-8.8	-8.9	-9.1	-5.8	-7.4
Hip circumference	16.7	72.0	96.2	-9.0	-9.1	-8.0	-7.8	-9.0	-8.9	-9.0	-8.7	-8.3	-8.5	-8.3	-8.6	-8.7	-9.8	-5.4	-7.8
Arm fat mass (left)	16.3	66.9	78.7	-8.7	-8.8	-7.8	-7.2	-8.7	-8.6	-8.7	-8.4	-7.9	-8.1	-8.4	-8.5	-8.6	-8.9	-5.8	-7.4
Arm fat-free mass (left)	15.3	77.8	132.2	-9.0	-9.3	-9.5	-6.8	-9.0	-9.4	-9.1	-9.2	-8.7	-8.0	-7.6	-9.3	-9.0	-11.5	-7.7	-7.1
Body fat percentage	15.1	59.8	69.3	-8.3	-8.3	-7.1	-7.1	-8.3	-8.2	-8.1	-8.0	-7.3	-7.9	-8.1	-7.9	-8.2	-8.0	-5.1	-7.2
Leg fat percentage (right)	14.7	53.3	62.4	-7.9	-7.9	-6.3	-6.6	-7.8	-7.8	-7.7	-7.7	-7.2	-7.3	-7.4	-7.6	-7.7	-7.6	-4.6	-6.8
Basal metabolic rate	14.5	80.3	134.9	-9.1	-9.4	-9.4	-7.2	-9.2	-9.4	-9.5	-9.3	-8.6	-8.3	-7.9	-9.3	-9.1	-11.6	-8.0	-7.3
Arm predicted mass (left)	14.5	73.7	126.2	-8.8	-9.0	-9.1	-6.8	-8.8	-9.0	-9.0	-8.9	-8.3	-7.9	-7.3	-8.9	-8.7	-11.2	-7.6	-7.0
Leg fat percentage (left)	14.4	52.0	61.3	-7.8	-7.8	-6.3	-6.4	-7.8	-7.8	-7.6	-7.6	-7.2	-7.1	-7.5	-7.6	-7.6	-7.4	-4.2	-6.6
Arm fat-free mass (right)	14.3	73.5	127.7	-8.8	-9.0	-8.9	-6.9	-8.8	-9.0	-9.1	-8.8	-8.3	-7.9	-7.4	-8.9	-8.7	-11.3	-7.2	-7.1
Arm predicted mass (right)	14.2	72.5	126.5	-8.7	-9.0	-8.9	-6.7	-8.7	-9.0	-9.1	-8.8	-8.4	-7.7	-7.3	-8.9	-8.7	-11.2	-7.1	-6.9
Trunk fat percentage	13.1	52.4	60.0	-7.7	-7.7	-6.7	-6.9	-7.7	-7.5	-7.5	-7.3	-6.5	-7.6	-7.5	-7.2	-7.5	-7.7	-5.3	-7.0
Friendships satisfaction	12.9	16.0	20.4	4.4	4.3	3.1	4.1	4.4	4.1	3.9	4.0	3.7	4.3	4.5	4.0	3.9	4.2	2.4	4.0
Leg fat-free mass (left)	12.7	67.2	104.7	-8.5	-8.6	-8.1	-7.0	-8.5	-8.5	-8.7	-8.3	-7.7	-7.9	-7.6	-8.3	-8.3	-10.2	-7.2	-7.0
Leg predicted mass (left)	12.6	66.8	104.0	-8.4	-8.6	-8.1	-7.0	-8.5	-8.5	-8.7	-8.3	-7.7	-7.8	-7.6	-8.3	-8.3	-10.2	-7.2	-7.0
Body mass index (BMI)	12.2	51.9	62.3	-7.7	-7.8	-6.4	-6.4	-7.8	-7.7	-7.7	-7.6	-7.1	-7.2	-7.9	-7.5	-7.6	-7.0	-4.3	-6.6
Whole body water mass	12.2	69.8	123.2	-8.4	-8.8	-8.8	-6.6	-8.5	-8.8	-8.9	-8.6	-8.1	-7.6	-7.2	-8.7	-8.5	-11.1	-7.5	-6.7
Whole body fat-free mass	12.1	69.2	122.7	-8.4	-8.7	-8.9	-6.5	-8.5	-8.7	-8.8	-8.6	-8.0	-7.5	-7.1	-8.6	-8.4	-11.1	-7.6	-6.6
Shortness of breath walking on level ground	11.6	13.9	20.9	-4.1	-3.8	-3.1	-4.5	-3.9	-3.5	-3.4	-3.4	-3.2	-4.4	-3.7	-3.2	-3.7	-4.0	-2.3	-4.6
Arm fat percentage (right)	11.3	44.7	56.8	-7.2	-7.2	-6.0	-6.2	-7.2	-7.1	-7.0	-7.0	-6.4	-6.9	-7.5	-6.9	-7.1	-6.3	-4.1	-6.2
Arm fat percentage (left)	11.3	45.2	57.9	-7.2	-7.2	-5.8	-6.3	-7.3	-7.1	-7.2	-6.9	-6.4	-7.0	-7.6	-6.9	-7.1	-6.4	-4.1	-6.3
Leg fat-free mass (right)	11.1	59.3	92.7	-7.9	-8.1	-7.7	-6.5	-8.0	-8.0	-8.2	-7.8	-7.3	-7.3	-7.2	-7.8	-7.8	-9.6	-6.8	-6.5
Leg predicted mass (right)	11.1	59.0	92.1	-7.9	-8.1	-7.6	-6.5	-7.9	-8.0	-8.2	-7.8	-7.3	-7.3	-7.3	-7.8	-7.7	-9.6	-6.7	-6.5
Cardiovascular Disease	10.5	34.5	44.7	-6.5	-6.3	-4.2	-6.5	-6.4	-5.9	-5.9	-5.9	-5.4	-6.7	-5.0	-5.5	-5.7	-6.5	-4.3	-6.5
Trunk fat-free mass	10.4	60.0	116.6	-7.7	-8.1	-8.7	-5.6	-7.8	-8.2	-8.2	-8.1	-7.6	-6.7	-6.1	-8.1	-7.8	-10.8	-7.3	-5.8
Trunk predicted mass	10.3	58.8	114.5	-7.6	-8.0	-8.6	-5.6	-7.7	-8.1	-8.1	-8.0	-7.5	-6.6	-6.0	-8.0	-7.8	-10.7	-7.2	-5.7
Smoking status: Previous	9.8	14.6	20.9	4.1	3.8	2.8	4.5	3.8	3.6	3.5	3.1	2.9	4.5	4.5	3.2	3.6	4.0	4.0	4.6
Comparative height size at age 10	9.5	52.4	125.4	-7.0	-7.3	-9.0	-5.6	-6.9	-7.3	-7.2	-7.0	-6.4	-6.4	-4.3	-7.2	-7.2	-11.2	-8.0	-5.6
Had other major operations	9.4	11.5	14.0	-3.6	-3.6	-3.4	-3.4	-3.7	-3.4	-3.4	-3.2	-3.2	-3.6	-3.7	-3.3	-3.7	-3.0	-1.8	-3.6
Past tobacco smoking	9.0	16.6	25.3	-4.3	-4.0	-3.1	-4.9	-4.0	-3.8	-3.7	-3.3	-2.9	-4.9	-4.5	-3.3	-3.7	-4.2	-4.7	-5.0
Body Mass Index (BMI) (2010)	8.9	12.2	15.4	-3.7	-3.7	-3.2	-3.3	-3.8	-3.7	-3.1	-3.5	-3.3	-3.6	-3.9	-3.5	-3.7	-3.1	-2.9	-3.5
High blood pressure (mother)	8.8	12.4	15.9	-3.8	-3.7	-3.1	-3.6	-3.7	-3.7	-3.7	-3.4	-3.6	-3.6	-2.9	-3.5	-3.9	-4.0	-2.3	-3.4
Alcohol intake versus 10 years previously	8.8	13.1	16.7	-4.0	-3.7	-1.9	-3.8	-3.8	-3.8	-4.1	-3.4	-3.8	-3.7	-3.0	-3.5	-3.8	-3.9	-3.2	-4.0
Qualifications: College or University degree	8.8	27.6	34.1	5.8	5.6	4.3	5.6	5.6	5.4	5.2	5.1	4.9	5.8	4.8	5.1	5.3	5.7	3.8	5.6
Alcohol drinker status: Never	8.7	10.4	12.8	-3.4	-3.6	-3.0	-2.6	-3.5	-3.5	-3.4	-3.4	-3.1	-3.0	-3.4	-3.6	-3.4	-3.2	-2.5	-2.8
Medication: Ramipril	8.6	11.1	14.7	-3.5	-3.5	-2.8	-3.8	-3.5	-3.1	-3.6	-3.2	-2.8	-3.8	-3.2	-2.8	-3.5	-3.2	-2.8	-3.7
Relative age of first facial hair	8.4	17.3	20.4	4.3	4.3	4.1	3.6	4.3	4.3	4.3	4.2	4.0	3.9	4.2	4.2	4.5	4.1	4.5	3.7
Pack years adult smoking proportion	8.3	12.7	16.2	-3.8	-3.7	-3.4	-3.3	-3.8	-3.6	-3.5	-3.4	-3.4	-3.5	-3.5	-3.6	-3.9	-4.0	-3.2	-3.3
Heart attack	8.3	10.7	13.1	-3.5	-3.6	-3.2	-2.9	-3.6	-3.6	-3.1	-3.6	-3.1	-3.2	-2.9	-3.4	-3.6	-3.5	-2.4	-2.9
Wears glasses or contact lenses	8.2	9.4	12.3	3.4	3.2	2.6	3.5	3.2	3.1	2.8	2.7	2.6	3.5	3.4	2.8	3.0	3.0	2.5	3.5
Comparative body size at age 10	7.8	21.6	31.7	-5.0	-5.0	-4.4	-4.3	-5.0	-4.9	-4.4	-4.8	-4.6	-4.7	-5.6	-4.8	-4.9	-4.0	-3.4	-4.3
Heart attack/myocardial infarction (self-reported)	7.8	10.0	12.4	-3.4	-3.5	-3.0	-2.8	-3.5	-3.5	-3.0	-3.5	-3.0	-3.2	-2.8	-3.3	-3.4	-3.4	-2.4	-2.8
Medication: Atenolol	7.7	9.6	11.6	-3.4	-3.4	-2.5	-3.1	-3.4	-3.3	-3.1	-3.3	-3.0	-3.1	-3.2	-3.1	-3.1	-3.4	-1.9	-3.1
Pack years of smoking	7.5	11.0	14.2	-3.5	-3.5	-3.1	-3.0	-3.5	-3.4	-3.2	-3.2	-3.2	-3.2	-3.2	-3.5	-3.7	-3.8	-2.9	-3.0
Forced expiratory volume in 1-second (FEV1), predicted	7.4	15.4	34.8	-3.9	-3.8	-3.8	-4.1	-3.8	-3.6	-4.3	-3.3	-3.3	-4.2	-2.8	-3.3	-3.5	-5.9	-4.6	-4.0
Osteoarthritis (self-reported)	7.3	9.5	14.0	-3.1	-3.4	-3.5	-2.0	-3.4	-3.4	-3.2	-3.7	-3.4	-2.4	-2.9	-3.5	-3.4	-3.5	-1.2	-2.0
Illnesses of siblings	7.1	10.0	12.5	3.3	3.3	3.0	2.8	3.3	3.3	3.1	3.3	3.0	2.9	3.0	3.2	3.2	3.5	3.1	2.9
Overall health rating	7.1	15.2	18.7	-4.1	-4.1	-3.6	-3.9	-4.1	-3.9	-4.0	-3.9	-3.6	-4.2	-3.4	-3.7	-4.1	-4.3	-3.3	-4.0
Illnesses of father: High blood pressure	6.9	8.5	10.5	-3.1	-3.0	-2.8	-3.2	-2.9	-2.8	-3.0	-2.6	-2.5	-3.2	-2.9	-2.6	-3.2	-2.8	-2.7	-3.1
Ever smoked	6.9	12.1	20.3	3.7	3.4	2.7	4.4	3.4	3.1	3.2	2.7	2.2	4.3	3.6	2.7	3.2	3.6	3.9	4.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	6.8	8.0	10.0	-3.0	-3.1	-2.6	-2.3	-3.0	-3.2	-2.9	-3.1	-3.0	-2.7	-3.1	-3.2	-2.9	-2.9	-1.5	-2.4
Age started oral contraceptive pill	6.6	8.3	15.0	2.9	2.9	2.5	2.8	2.9	2.8	3.0	2.5	2.3	3.0	2.9	2.6	3.1	2.8	3.9	2.8
Illness, injury, bereavement, stress in last 2 years	6.5	8.0	10.7	2.9	2.9	3.2	1.9	2.9	3.2	2.6	3.0	3.1	2.3	3.1	3.3	3.0	2.9	2.4	2.1
Alzheimer’s Disease (in mother)	6.4	7.5	9.9	2.9	3.0	2.4	2.6	2.9	2.9	3.1	2.9	2.6	2.7	2.8	2.8	2.5	3.1	1.9	2.5
Bipolar Disorder (2011)	6.3	6.1	8.9	2.6	2.3	2.3	2.9	2.4	2.2	2.4	1.9	2.0	2.9	2.6	2.0	2.4	2.8	2.7	3.0
Father’s age at death	6.3	8.4	11.9	3.0	3.2	3.1	2.6	3.0	3.0	2.5	2.9	2.7	2.8	2.5	2.9	2.8	3.4	3.2	2.4
Relative age voice broke	6.1	9.3	11.7	3.2	3.1	3.2	2.9	3.2	3.0	3.4	3.0	3.4	3.0	2.7	3.0	3.2	3.4	1.9	2.8
Type 2 Diabetes (T2D) (2018)	5.9	11.0	14.7	-3.6	-3.5	-2.5	-3.3	-3.5	-3.4	-3.7	-3.2	-3.0	-3.6	-3.8	-3.3	-3.4	-3.4	-1.8	-3.4
High blood pressure (siblings)	5.9	8.5	9.8	-3.1	-3.1	-2.3	-2.7	-3.1	-3.0	-3.1	-3.1	-2.8	-3.0	-2.8	-2.9	-2.9	-3.0	-2.9	-2.8
Hearing difficulty/problems with background noise	5.8	9.3	17.8	3.4	2.9	1.9	4.2	3.1	2.6	3.0	2.1	1.9	4.0	3.3	2.2	2.8	2.7	3.2	4.1
Age at last live birth	5.5	8.0	12.2	2.9	3.2	3.2	1.6	3.1	3.3	2.6	3.5	3.4	2.1	2.8	3.4	2.6	2.8	2.1	1.6
Supplements: Vitamin C	5.4	6.4	10.7	2.6	2.9	3.2	1.3	2.7	3.1	2.2	3.3	2.7	1.8	2.1	3.1	3.1	2.5	0.7	1.3
Fasting Glucose	5.1	6.1	8.4	-2.5	-2.7	-2.5	-1.5	-2.6	-2.8	-2.0	-2.9	-2.9	-1.9	-2.8	-2.8	-2.7	-2.5	-1.7	-1.9
Qualifications: CSEs or equivalent	5.1	6.7	9.8	-2.8	-2.6	-2.5	-2.9	-2.7	-2.4	-2.0	-2.3	-1.8	-3.1	-2.3	-2.3	-2.4	-3.1	-2.9	-2.9
Medication for pain relief, constipation, heartburn	5.1	8.7	11.3	3.2	3.2	2.8	3.1	3.2	2.9	2.7	2.9	2.5	3.4	3.1	2.7	3.1	3.0	1.9	3.1
Breastfed as a baby	5.0	6.2	9.5	2.7	2.5	2.0	3.0	2.6	2.3	2.5	2.2	2.0	3.1	2.6	2.1	2.4	2.2	2.6	2.9
Mineral and other dietary supplements	5.0	6.7	8.6	-2.7	-2.7	-2.2	-2.4	-2.7	-2.7	-2.8	-2.5	-2.4	-2.6	-2.4	-2.7	-2.6	-2.7	-2.9	-2.4
Major Depression (MDD)	4.9	6.0	7.3	2.7	2.6	2.6	2.4	2.7	2.5	2.3	2.5	2.2	2.5	2.4	2.6	2.6	2.2	1.9	2.2
Exposure to tobacco smoke outside home	4.9	6.6	9.0	-2.8	-2.7	-2.2	-3.0	-2.7	-2.5	-2.1	-2.4	-2.4	-3.0	-2.3	-2.3	-2.4	-2.7	-2.5	-2.9
Serious illness, injury or assault to yourself	4.8	5.8	10.7	-2.3	-2.5	-3.3	-1.2	-2.4	-2.6	-2.5	-2.4	-2.4	-1.7	-2.1	-2.8	-2.7	-2.6	-2.7	-1.4
Tinnitus: Yes, but not now, but have in the past	4.7	5.1	6.7	-2.3	-2.4	-2.3	-1.9	-2.3	-2.4	-2.3	-2.4	-2.0	-2.1	-1.5	-2.3	-2.4	-2.6	-2.5	-2.1
Angina (self-reported)	4.7	6.1	7.6	-2.7	-2.7	-2.4	-2.5	-2.7	-2.5	-2.5	-2.5	-2.3	-2.7	-2.8	-2.4	-2.5	-2.3	-1.0	-2.5
Pain all over the body in last month	4.6	4.9	7.5	-2.3	-2.3	-2.0	-1.6	-2.3	-2.5	-2.7	-2.4	-2.3	-1.9	-2.2	-2.5	-2.6	-2.4	-0.9	-1.7
Medication: Co-codamol	4.5	5.3	6.6	-2.3	-2.4	-2.2	-2.0	-2.5	-2.3	-2.5	-2.4	-2.1	-2.4	-1.5	-2.3	-2.5	-2.6	-2.5	-2.1
Mouth/teeth dental problems: Bleeding gums	4.4	5.7	9.0	-2.7	-2.7	-1.9	-1.7	-2.5	-2.9	-2.5	-2.6	-2.5	-2.1	-2.0	-3.0	-2.5	-2.5	-1.2	-1.8
Deep venous thrombosis (DVT) (self-reported)	4.4	5.7	7.7	-2.3	-2.6	-2.4	-1.9	-2.5	-2.5	-2.6	-2.6	-2.3	-2.0	-2.8	-2.4	-2.5	-2.6	-2.0	-1.9
Vascular/heart problems diagnosed by doctor	4.3	11.6	15.7	3.8	3.8	2.2	3.8	3.8	3.5	3.4	3.7	3.1	4.0	3.2	3.2	3.4	3.5	1.5	3.8
Qualifications: None of the above	4.2	9.0	11.5	-3.3	-3.4	-2.8	-2.6	-3.3	-3.4	-2.5	-3.4	-3.1	-3.0	-3.1	-3.4	-3.0	-3.0	-1.2	-2.8
Number of full sisters	4.2	5.1	6.5	-2.5	-2.4	-1.8	-2.1	-2.5	-2.3	-2.3	-2.4	-2.1	-2.3	-1.7	-2.4	-2.5	-2.4	-1.9	-2.2
Pain type(s) experienced in last month: Hip pain	4.2	5.2	7.0	-2.4	-2.5	-2.5	-2.0	-2.4	-2.4	-2.1	-2.5	-2.2	-2.2	-2.3	-2.3	-2.4	-2.6	-1.4	-2.0
Angina	4.1	5.4	7.1	-2.6	-2.5	-2.2	-2.5	-2.5	-2.3	-2.4	-2.3	-2.2	-2.6	-2.7	-2.2	-2.3	-2.2	-0.8	-2.4
Diabetes (mother)	4.1	5.2	6.7	-2.3	-2.2	-2.3	-2.4	-2.4	-2.0	-2.6	-1.9	-1.6	-2.6	-2.5	-2.0	-2.4	-2.4	-2.2	-2.5
Taking other prescription medications	4.1	6.3	9.2	-2.7	-2.7	-1.6	-2.5	-2.8	-2.5	-3.0	-2.6	-2.1	-2.8	-2.4	-2.4	-2.7	-2.8	-1.7	-2.6
Standing height	4.0	40.1	123.2	-5.8	-6.0	-7.8	-4.8	-5.7	-6.0	-6.3	-5.8	-5.2	-5.4	-3.1	-5.8	-5.8	-11.1	-8.2	-4.8
Long-standing illness, disability or infirmity	4.0	6.1	9.3	-2.5	-2.7	-2.3	-1.8	-2.7	-2.7	-3.1	-2.8	-2.4	-2.1	-2.7	-2.7	-2.7	-2.7	-1.2	-1.8
Pain experienced in last month	4.0	6.7	8.4	2.8	2.7	2.3	2.5	2.8	2.6	2.9	2.5	2.6	2.7	2.9	2.5	2.8	2.7	0.4	2.7
Height	3.9	74.9	243.4	-7.7	-8.4	-9.8	-5.2	-7.8	-8.5	-8.9	-8.5	-7.9	-6.4	-4.2	-8.5	-8.2	-15.6	-11.4	-5.5
Supplements: Glucosamine	3.9	5.1	7.4	2.5	2.4	1.5	2.3	2.4	2.3	2.5	2.1	1.9	2.4	1.9	2.3	2.1	2.3	2.7	2.4
Qualifications: A levels/AS levels or equivalent	3.9	8.7	13.5	3.1	3.0	2.9	2.7	3.0	3.0	2.9	2.9	2.6	3.0	1.8	2.9	3.1	3.3	3.7	2.8
Chest pain or discomfort	3.9	5.6	8.5	-2.6	-2.4	-2.0	-2.8	-2.4	-2.2	-2.6	-2.1	-2.1	-2.8	-2.1	-2.0	-2.4	-2.8	-0.7	-2.9
Hypertension (Self-reported)	3.9	10.9	13.7	-3.7	-3.7	-2.4	-3.4	-3.6	-3.5	-3.3	-3.7	-3.3	-3.6	-3.2	-3.3	-3.3	-3.6	-0.9	-3.4
Unable to work because of sickness or disability	3.9	5.1	7.7	-2.4	-2.2	-1.5	-2.7	-2.3	-2.1	-2.6	-1.9	-1.7	-2.7	-2.4	-1.8	-2.1	-2.4	-1.9	-2.8
Schizophrenia vs Biploar Disorder	3.8	5.0	15.7	-2.1	-2.0	-2.5	-2.3	-2.0	-1.9	-1.8	-1.6	-1.6	-2.4	-1.7	-1.7	-2.4	-2.3	-4.0	-2.4
Happiness	3.8	4.6	7.0	2.3	2.1	1.9	2.4	2.3	2.1	2.0	1.9	2.1	2.3	2.6	2.0	2.2	2.6	1.0	2.3
Heart disease (siblings)	3.8	4.6	8.4	-2.2	-2.1	-2.3	-1.6	-2.1	-2.3	-2.0	-2.2	-2.1	-1.8	-1.4	-2.3	-2.3	-2.6	-2.9	-1.8
Impedance of arm (left)	3.7	17.2	23.8	4.4	4.6	4.0	2.7	4.5	4.8	4.3	4.8	4.9	3.3	4.1	4.9	4.5	4.4	1.7	2.9
Blood clot in the leg (DVT)	3.7	4.8	6.4	-2.1	-2.3	-2.1	-1.9	-2.3	-2.2	-2.3	-2.3	-2.1	-1.9	-2.5	-2.1	-2.3	-2.5	-2.1	-1.9
Lung FVC	3.6	18.6	37.6	4.5	4.5	4.3	4.5	4.2	4.1	3.6	4.2	3.2	4.9	2.9	3.8	4.0	6.1	4.4	4.6
Chronotype (morning person)	3.6	8.4	12.9	3.2	3.0	2.0	3.2	3.1	2.9	2.7	2.6	2.7	3.3	3.6	2.7	2.7	3.1	1.8	3.3
High blood pressure	3.6	10.0	12.7	-3.5	-3.6	-2.3	-3.3	-3.5	-3.3	-3.1	-3.5	-3.0	-3.5	-3.0	-3.1	-3.2	-3.3	-0.8	-3.3
Medication: Bendroflumethiazide	3.6	5.5	8.7	-2.6	-2.5	-1.4	-3.0	-2.5	-2.3	-2.4	-2.3	-2.1	-2.9	-2.1	-1.9	-2.1	-2.6	-1.0	-2.8
Diabetes diagnosed by doctor	3.5	5.7	7.8	-2.5	-2.5	-2.4	-2.1	-2.5	-2.5	-2.8	-2.4	-2.1	-2.4	-2.7	-2.4	-2.7	-2.5	-1.1	-2.2
Tinnitus: Yes, now most or all of the time	3.5	4.0	11.4	2.1	1.6	0.6	3.4	1.8	1.2	1.7	1.0	0.9	2.9	2.1	0.8	1.4	1.5	2.7	3.3
Rheumatoid Arthritis	3.4	4.6	5.8	-2.3	-2.3	-2.3	-1.9	-2.2	-2.3	-2.1	-2.1	-2.0	-2.1	-2.4	-2.2	-2.4	-2.4	-1.4	-1.9
Vitamin and mineral supplements	3.4	4.7	7.6	-2.2	-2.4	-1.5	-1.2	-2.3	-2.6	-2.4	-2.6	-2.8	-1.3	-2.6	-2.8	-2.4	-2.0	-0.8	-1.2
Age at first live birth	3.4	6.0	8.0	2.6	2.7	2.3	1.8	2.7	2.7	2.1	2.8	2.8	2.1	2.3	2.8	2.4	2.5	2.4	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	3.3	4.4	6.4	-2.3	-2.3	-1.5	-1.7	-2.3	-2.4	-2.1	-2.3	-2.5	-1.9	-1.8	-2.4	-2.4	-2.5	-0.5	-1.7
Intelligence (Savage-Jansen 2018)	3.1	9.6	13.1	3.3	3.2	3.6	2.9	3.2	3.1	3.1	3.0	2.7	3.3	2.9	3.1	3.4	3.1	2.5	3.1
Impedance of arm (right)	3.1	14.5	19.8	4.0	4.2	3.6	2.6	4.1	4.4	4.1	4.4	4.5	3.1	3.8	4.4	4.0	4.1	1.5	2.8
Headache pain in last month	3.1	5.4	11.3	-2.5	-2.1	-1.4	-3.3	-2.3	-1.8	-2.1	-1.5	-1.5	-3.2	-2.8	-1.5	-2.0	-2.2	-1.9	-3.4
Medication: Blood pressure	3.1	5.5	8.9	-2.6	-2.5	-1.5	-2.9	-2.6	-2.2	-2.6	-2.3	-1.6	-3.0	-2.4	-1.9	-2.4	-2.2	-1.5	-2.8
Medication: Aspirin	3.1	4.1	5.1	-2.1	-2.3	-1.8	-1.8	-2.2	-2.1	-2.2	-2.2	-1.6	-2.1	-1.8	-2.1	-2.2	-1.9	-2.1	-1.7
Number of self-reported non-cancer illnesses	3.1	5.4	7.8	-2.5	-2.6	-1.7	-2.1	-2.6	-2.4	-2.5	-2.8	-2.6	-2.3	-2.2	-2.4	-2.2	-2.6	0.0	-2.2
Irritability	3.1	5.2	6.6	2.5	2.3	1.9	2.5	2.4	2.3	2.4	2.1	2.1	2.4	2.6	2.1	2.3	2.3	1.8	2.5
Alzheimer’s Disease (including proxy)	3.0	4.3	6.4	2.2	2.3	1.8	1.9	2.2	2.3	2.3	2.3	2.1	1.8	1.9	2.2	2.0	2.5	1.5	1.7
Blood White Count	3.0	22.3	33.4	5.3	4.8	3.1	5.7	5.0	4.6	5.0	4.0	4.4	5.5	3.8	4.2	4.5	5.7	3.3	5.8
Suffer from ‘nerves’	3.0	4.8	7.1	-2.3	-2.3	-1.8	-2.1	-2.2	-2.1	-2.3	-2.1	-1.6	-2.4	-2.2	-2.0	-2.2	-2.4	-2.7	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.0	6.4	11.8	2.6	2.5	2.8	2.6	2.4	2.4	1.7	2.4	1.8	2.7	2.3	2.2	2.4	3.2	3.4	2.5
Number of operations (self-reported)	3.0	4.4	5.9	-2.1	-2.3	-2.3	-1.6	-2.3	-2.3	-2.2	-2.3	-2.0	-1.9	-2.4	-2.2	-2.4	-2.1	-1.0	-1.7
Mouth/teeth dental problems	2.9	4.4	5.6	2.3	2.3	1.7	1.9	2.1	2.3	2.1	2.1	1.7	2.2	2.4	2.3	2.1	2.1	2.0	2.1
Medication for cholesterol, blood pressure or diabetes	2.9	4.8	8.4	2.5	2.4	0.9	2.8	2.4	2.1	2.4	2.1	1.5	2.9	2.1	1.7	2.2	2.1	0.7	2.8
Back pain experienced in last month	2.9	4.3	7.5	-2.1	-2.2	-2.7	-1.6	-2.2	-2.1	-2.0	-2.2	-2.0	-1.9	-1.9	-2.1	-2.6	-2.3	-0.7	-1.7
LDL Cholesterol	2.8	4.4	6.0	-2.1	-2.3	-2.2	-1.4	-2.2	-2.3	-1.7	-2.3	-2.4	-2.0	-2.1	-2.4	-2.0	-2.2	-1.8	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	2.8	2.9	6.4	-1.7	-1.7	-1.0	-1.6	-1.8	-1.6	-2.0	-1.4	-1.2	-1.7	-2.5	-1.5	-1.6	-1.6	-2.3	-1.5
Guilty feelings	2.8	4.2	6.7	2.2	2.1	2.1	2.6	2.2	1.9	1.7	1.8	2.0	2.4	2.3	1.8	2.0	1.8	0.8	2.5
Type 2 Diabetes (T2D) (2012)	2.7	3.2	4.6	-1.9	-2.0	-1.2	-2.0	-1.9	-2.0	-1.5	-2.1	-2.0	-1.6	-1.6	-1.8	-2.0	-1.7	0.7	-1.9
Diastolic blood pressure, automated reading	2.7	8.3	11.5	-2.9	-3.2	-3.4	-1.9	-3.0	-3.2	-2.8	-3.2	-2.7	-2.5	-3.0	-3.3	-3.4	-3.1	-2.1	-2.1
Number of treatments/medications taken	2.6	4.7	5.8	-2.3	-2.4	-1.9	-2.3	-2.4	-2.1	-2.0	-2.4	-2.0	-2.4	-2.2	-2.0	-2.2	-2.3	-1.2	-2.3
Medication: Metformin	2.6	3.6	5.9	-2.0	-2.0	-1.5	-1.7	-2.1	-2.0	-2.4	-2.0	-1.8	-1.9	-1.8	-1.9	-2.2	-1.9	-0.5	-1.7
Stomach or abdominal pain in last month	2.6	3.2	6.4	-1.9	-1.6	-1.0	-2.4	-1.8	-1.3	-1.9	-1.1	-1.1	-2.5	-1.8	-1.1	-1.7	-2.0	-2.0	-2.5
Commuting to job workplace: Cycle	2.6	3.2	6.4	2.0	1.8	0.9	2.4	1.8	1.5	1.5	1.3	0.8	2.5	1.3	1.4	1.6	1.8	2.3	2.3
Medication: Aspirin	2.5	3.2	4.1	-1.9	-2.0	-1.4	-1.5	-2.0	-1.9	-2.0	-2.0	-1.5	-1.8	-1.7	-1.9	-1.9	-1.7	-1.9	-1.4
Impedance of whole body	2.5	12.8	17.6	3.7	4.0	3.2	2.4	3.9	4.1	3.9	4.2	4.2	2.9	4.1	4.2	3.8	3.4	1.3	2.4
Illnesses of father: Heart disease	2.4	3.3	5.9	-1.7	-1.9	-2.4	-1.0	-1.8	-2.0	-1.4	-2.0	-2.0	-1.2	-1.9	-2.1	-2.0	-2.1	-2.0	-0.9
Bipolar Disorder (2018)	2.3	3.7	8.5	1.9	1.7	1.7	2.4	1.8	1.4	1.7	1.1	1.3	2.6	1.5	1.4	2.2	1.6	2.9	2.5
Heel T-Score	2.3	17.9	34.1	4.2	4.2	3.6	3.9	4.3	4.0	4.8	3.9	3.9	4.1	3.3	4.0	4.3	5.8	4.8	4.0
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	3.0	-1.6	-1.6	-1.7	-1.6	-1.6	-1.5	-1.5	-1.4	-1.2	-1.7	-1.7	-1.5	-1.7	-1.7	-1.7	-1.6
Medication: Blood pressure	2.3	4.4	6.9	-2.3	-2.4	-2.0	-1.6	-2.3	-2.4	-1.9	-2.6	-2.4	-1.8	-1.4	-2.4	-2.1	-2.5	-0.9	-1.7
Alcohol drinker status: Previous	2.3	2.6	4.7	-1.7	-1.5	-1.1	-2.2	-1.7	-1.3	-1.9	-1.2	-1.4	-2.0	-1.6	-1.2	-1.5	-1.7	-1.3	-2.0
Diabetes (self-reported)	2.2	3.4	4.9	-1.9	-1.9	-1.8	-1.3	-1.9	-2.0	-2.2	-2.0	-2.1	-1.5	-2.1	-2.0	-2.1	-1.9	-0.2	-1.4
Hair/balding pattern: Pattern 3	2.2	3.3	4.4	2.0	2.0	1.8	1.8	2.0	2.0	1.7	1.9	1.7	1.8	1.7	1.8	2.1	2.0	0.6	1.8
High cholesterol (Self-reported)	2.2	3.9	5.7	-2.1	-2.2	-1.7	-1.6	-2.2	-2.1	-2.0	-2.3	-2.0	-1.9	-1.6	-2.1	-2.4	-2.3	-0.8	-1.7
HDL Cholesterol	2.1	3.5	6.5	1.6	1.9	2.5	0.3	1.9	2.2	1.9	2.3	2.5	0.8	1.5	2.5	2.3	2.2	0.4	0.4
Bilateral oophorectomy (both ovaries removed)	2.1	2.5	3.3	-1.6	-1.8	-1.4	-1.5	-1.8	-1.6	-1.6	-1.8	-1.5	-1.6	-1.6	-1.6	-1.6	-1.8	-0.6	-1.6
Illnesses of father: None of the above (group 1)	2.1	2.6	4.4	1.6	1.8	1.9	0.9	1.6	1.9	1.4	2.1	2.1	1.0	1.9	1.9	1.6	1.8	0.4	0.8
Blood Platelet Count	2.0	22.8	70.6	4.8	4.6	2.9	4.9	4.6	4.2	5.1	4.2	4.5	4.8	1.9	4.0	3.9	8.4	5.9	4.7
Medication: Allopurinol	2.0	2.6	4.1	-1.7	-1.8	-1.1	-1.7	-1.7	-1.6	-1.7	-1.8	-1.0	-1.9	-1.0	-1.5	-1.6	-1.7	-2.0	-1.7
Average weekly champagne plus white wine intake	2.0	2.7	3.8	1.8	1.7	1.5	1.4	1.8	1.8	1.5	1.8	1.8	1.6	1.7	1.8	2.0	1.6	0.4	1.6
Ever had prostate specific antigen (PSA) test	2.0	2.4	6.0	1.6	1.5	0.5	2.4	1.5	1.2	1.3	1.0	0.9	2.2	1.2	0.8	1.5	1.6	1.7	2.2
Worry (Nagel 2018)	1.9	3.9	6.8	-1.9	-2.0	-2.6	-1.2	-1.9	-2.1	-1.7	-2.2	-2.0	-1.5	-1.7	-2.1	-2.2	-2.3	-2.4	-1.3
Lupus	1.9	2.8	5.0	-1.9	-1.7	-1.1	-1.2	-1.7	-2.0	-1.2	-1.7	-2.1	-1.4	-2.2	-2.0	-1.5	-1.8	-1.4	-1.4
Current tobacco smoking	1.9	3.1	5.4	-1.7	-1.9	-1.4	-0.8	-1.9	-2.0	-2.0	-2.0	-1.9	-1.1	-2.3	-2.1	-2.2	-1.7	-1.5	-0.8
Fluid intelligence score	1.9	4.0	7.2	2.3	2.0	1.0	2.6	2.2	1.9	2.0	1.8	1.5	2.5	2.0	1.7	2.0	2.1	0.4	2.7
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	5.2	-1.1	-1.4	-2.3	-0.0	-1.3	-1.6	-1.4	-1.8	-1.8	-0.4	-1.4	-1.7	-1.5	-1.6	-2.2	-0.1
Medication for cholesterol	1.9	2.8	4.7	1.8	2.0	1.6	1.3	1.9	2.0	1.3	2.2	1.9	1.5	1.1	1.9	1.8	2.0	0.8	1.4
Reaction Time	1.8	3.4	6.4	-2.0	-1.9	-1.4	-2.1	-1.9	-1.7	-1.5	-1.7	-1.4	-2.3	-1.7	-1.5	-1.7	-1.7	-2.5	-2.1
Average weekly fortified wine intake	1.8	2.1	2.6	1.5	1.5	1.6	1.3	1.5	1.5	1.0	1.5	1.5	1.3	1.5	1.4	1.5	1.4	1.6	1.3
Medication: Ventolin 100micrograms inhaler	1.8	2.3	3.7	-1.6	-1.5	-1.5	-1.5	-1.4	-1.4	-1.0	-1.3	-1.5	-1.6	-1.7	-1.4	-1.2	-1.9	-1.7	-1.5
Worry too long after embarrassment	1.8	3.1	12.5	1.7	1.1	-0.1	3.5	1.4	0.7	1.5	0.3	0.5	2.9	1.4	0.2	1.0	1.2	1.8	3.4
Medication: Omeprazole	1.8	2.1	4.0	-1.4	-1.5	-1.2	-1.0	-1.5	-1.5	-1.6	-1.7	-2.0	-1.2	-1.3	-1.5	-1.5	-1.6	1.2	-1.0
Commuting to job workplace: Walk	1.8	2.0	3.4	1.6	1.5	1.8	1.5	1.4	1.3	0.9	1.1	0.9	1.7	0.8	1.3	1.5	1.6	1.4	1.5
Verbal and Numeric Reasoning (VNR)	1.7	4.1	7.2	2.3	2.0	1.6	2.7	2.2	1.8	1.7	1.8	1.5	2.6	1.8	1.7	2.1	2.2	1.1	2.7
Smoking Status	1.7	4.0	11.7	2.1	1.7	1.2	3.3	1.8	1.4	1.4	0.9	0.9	3.0	1.9	0.9	1.4	1.9	2.2	3.4
Pulse wave reflection index	1.7	2.2	4.5	1.3	1.5	2.0	1.0	1.5	1.5	1.5	1.6	1.1	1.2	1.5	1.3	1.6	1.1	2.1	1.0
Emphysema/chronic bronchitis	1.7	1.9	3.3	-1.5	-1.5	-0.4	-1.2	-1.5	-1.6	-1.2	-1.4	-1.7	-1.4	-1.5	-1.6	-1.1	-1.8	0.5	-1.3
Commuting to job workplace: Car/motor vehicle	1.7	1.9	3.0	-1.5	-1.6	-1.6	-0.8	-1.5	-1.6	-1.1	-1.6	-1.2	-1.2	-1.5	-1.7	-1.7	-1.0	-0.8	-0.9
Eye problems/disorders: Glaucoma	1.7	2.0	2.8	1.6	1.6	0.7	1.4	1.5	1.7	1.4	1.4	1.7	1.4	1.6	1.6	1.6	1.2	0.2	1.4
Supplements: Fish oil (including cod liver oil)	1.7	2.2	3.2	1.6	1.5	1.3	1.6	1.6	1.4	1.6	1.3	1.1	1.8	1.1	1.4	1.6	1.4	1.7	1.7
Sitting height	1.6	11.1	28.1	-3.2	-3.4	-4.2	-2.7	-3.2	-3.3	-3.4	-3.3	-2.8	-3.1	-2.4	-3.2	-3.5	-5.3	-2.9	-2.5
Prospective memory result	1.6	2.0	4.6	-1.5	-1.3	-0.0	-1.9	-1.5	-1.2	-2.1	-1.2	-1.6	-1.6	-0.9	-0.9	-1.2	-1.8	-0.2	-1.8
Exposure to tobacco smoke at home	1.6	1.8	3.4	-1.3	-1.3	-1.3	-1.0	-1.4	-1.4	-1.4	-1.4	-1.4	-1.1	-1.3	-1.4	-1.3	-1.2	-1.8	-1.0
Ever depressed for a whole week	1.6	1.9	5.7	1.5	1.4	0.8	1.5	1.4	1.4	1.2	1.2	1.5	1.4	2.4	1.3	1.2	1.3	0.2	1.4
Triglycerides	1.5	2.5	4.0	-1.7	-1.7	-1.6	-1.3	-1.7	-1.7	-1.6	-1.7	-2.0	-1.4	-1.2	-1.8	-1.7	-2.0	-0.3	-1.4
Alcohol usually taken with meals	1.5	2.5	4.5	1.8	1.5	0.7	2.1	1.5	1.4	1.3	1.2	0.9	2.0	1.5	1.2	1.7	1.6	2.1	1.9
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	5.0	1.4	1.2	0.4	2.2	1.3	0.9	1.1	0.8	0.7	2.0	1.5	0.6	0.9	1.3	1.2	2.2
Family relationship satisfaction	1.5	1.8	3.1	1.5	1.3	1.1	1.5	1.5	1.3	1.1	1.1	1.2	1.6	1.8	1.3	1.2	1.5	0.7	1.4
Average weekly beer plus cider intake	1.5	2.2	3.6	-1.5	-1.7	-0.9	-1.1	-1.6	-1.7	-1.7	-1.8	-1.9	-1.1	-1.5	-1.6	-1.5	-1.4	-1.1	-1.0
Ever had hysterectomy (womb removed)	1.4	1.6	2.7	-1.3	-1.5	-0.7	-0.9	-1.6	-1.4	-1.6	-1.6	-1.4	-1.2	-1.3	-1.4	-1.3	-1.1	-0.2	-1.0
Age when periods started (menarche)	1.4	3.2	4.9	1.8	1.9	2.2	1.6	1.9	1.9	1.6	1.9	1.6	1.7	1.8	1.8	2.0	1.7	1.8	1.6
Medication: Lansoprazole	1.4	1.6	3.2	-1.2	-1.3	-0.8	-1.2	-1.3	-1.1	-1.7	-1.2	-0.9	-1.3	-1.1	-1.1	-1.5	-1.1	-1.8	-1.2
Medication: Gliclazide	1.4	1.6	3.7	-1.2	-1.3	-1.3	-0.6	-1.3	-1.4	-1.3	-1.5	-1.4	-0.8	-1.9	-1.4	-1.5	-1.2	0.4	-0.7
Ulcerative Colitis	1.3	1.9	2.7	1.5	1.5	1.5	1.6	1.4	1.4	1.1	1.5	1.5	1.6	1.3	1.2	1.3	1.3	0.4	1.6
Townsend deprivation index at recruitment	1.3	1.9	2.7	1.5	1.6	1.4	1.0	1.5	1.6	1.5	1.6	1.4	1.1	1.3	1.6	1.5	1.4	-0.2	1.0
Had menopause	1.3	1.6	2.5	1.4	1.3	0.5	1.1	1.4	1.4	1.6	1.2	1.1	1.3	1.2	1.3	1.5	1.3	1.1	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	3.8	-1.7	-1.5	-0.6	-1.8	-1.5	-1.4	-1.5	-1.3	-0.9	-2.0	-0.9	-1.2	-1.6	-1.7	-1.4	-1.8
Illnesses of siblings: Diabetes	1.3	1.5	2.3	-1.4	-1.3	-0.5	-1.4	-1.4	-1.3	-1.3	-1.2	-1.2	-1.4	-1.1	-1.2	-1.0	-1.2	-1.2	-1.5
Age at First Birth	1.2	1.8	3.7	1.2	1.4	1.8	0.6	1.5	1.3	1.4	1.5	1.4	0.9	1.0	1.5	1.3	1.3	1.9	0.6
Impedance of leg (left)	1.2	5.7	12.6	2.5	2.6	1.8	1.9	2.7	2.6	2.6	2.6	2.5	2.2	3.6	2.6	2.5	1.6	0.9	1.8
Gout (self-reported)	1.2	1.7	5.4	-1.3	-1.3	-1.0	-1.6	-1.2	-1.0	-1.0	-1.2	-0.3	-1.7	-0.6	-0.8	-1.2	-1.3	-2.3	-1.6
Financial situation satisfaction	1.2	1.5	2.9	1.3	1.3	1.7	1.1	1.3	1.2	1.0	1.1	0.8	1.4	1.4	1.2	1.2	1.4	0.1	0.9
Cholesterol lowering medication	1.2	1.7	2.9	-1.4	-1.5	-1.0	-0.9	-1.5	-1.5	-1.3	-1.7	-1.4	-1.1	-1.2	-1.6	-1.4	-1.3	-0.5	-1.1
Frequency of depressed mood in last 2 weeks	1.1	1.5	2.7	-1.2	-1.3	-0.2	-0.6	-1.3	-1.5	-1.6	-1.5	-1.7	-0.7	-1.1	-1.5	-1.5	-1.4	-0.4	-0.6
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	2.6	-1.1	-1.3	-1.1	-0.8	-1.4	-1.2	-1.6	-1.3	-1.1	-1.1	-0.6	-1.3	-1.2	-1.2	-1.6	-0.9
Diabetes (father)	1.1	1.4	2.2	-1.2	-1.3	-1.3	-0.7	-1.3	-1.4	-0.9	-1.5	-1.3	-0.9	-1.4	-1.4	-1.3	-0.9	0.1	-0.8
Impedance of leg (right)	1.1	5.4	13.6	2.4	2.6	1.8	1.6	2.6	2.6	2.4	2.7	2.6	2.0	3.7	2.6	2.4	1.4	0.4	1.6
Multivitamins +/- minerals	1.1	1.4	2.7	1.2	1.3	-0.2	0.6	1.3	1.5	1.6	1.5	1.7	0.6	1.4	1.6	1.0	0.9	0.8	0.6
Time employed in main current job	1.1	1.2	2.6	-1.1	-0.9	-1.1	-1.6	-1.1	-0.7	-1.2	-0.5	-0.4	-1.6	-0.8	-0.6	-1.1	-1.2	-1.2	-1.6
Medication: Cholesterol lowering	1.1	1.7	3.7	-1.5	-1.4	-0.2	-1.9	-1.4	-1.2	-1.3	-1.2	-0.8	-1.9	-0.9	-0.9	-1.4	-1.3	-0.2	-1.8
Loud music exposure frequency	1.1	1.2	1.8	-1.2	-1.1	-1.3	-1.1	-1.1	-1.1	-0.8	-1.2	-0.9	-1.2	-1.3	-1.0	-1.0	-1.2	-0.1	-1.1
Medication: Paracetamol	1.1	1.8	2.5	-1.5	-1.4	-1.3	-1.5	-1.4	-1.3	-1.1	-1.3	-1.3	-1.4	-1.6	-1.2	-1.2	-1.5	-1.1	-1.5
Knee pain experienced in last month	1.1	1.8	2.5	-1.4	-1.4	-1.0	-1.2	-1.5	-1.3	-1.5	-1.4	-1.6	-1.3	-0.9	-1.4	-1.5	-1.4	0.9	-1.2
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	2.3	-1.1	-1.2	-0.9	-0.6	-1.2	-1.2	-1.3	-1.3	-1.5	-0.9	-1.2	-1.2	-1.3	-1.1	1.0	-0.6
Birth weight of first child	1.0	1.8	3.2	-1.5	-1.3	-0.6	-1.4	-1.4	-1.4	-1.7	-1.1	-1.8	-1.2	-1.0	-1.4	-1.3	-1.7	0.7	-1.3
Mother’s age at death	1.0	1.2	4.2	1.1	1.2	1.0	1.1	1.0	1.0	0.9	1.0	0.6	1.2	0.6	0.9	1.0	1.2	2.1	1.0
Medication for hormone replacement therapy	0.9	1.0	2.1	-1.2	-1.0	-0.7	-1.3	-1.0	-1.0	-0.8	-0.8	-1.0	-1.2	-0.8	-0.9	-0.9	-1.5	-0.3	-1.3
Medication: Simvastatin	0.9	1.4	4.4	-1.3	-1.0	0.2	-2.1	-1.1	-0.7	-1.1	-0.7	-0.4	-1.8	-0.8	-0.5	-1.0	-1.2	-0.7	-2.0
Asthma	0.9	1.8	2.9	1.4	1.5	1.1	1.2	1.5	1.5	1.7	1.4	1.1	1.3	1.2	1.4	1.5	1.1	1.1	1.2
Asthma (self-reported)	0.9	1.8	2.8	1.4	1.5	0.9	1.3	1.5	1.4	1.7	1.4	1.1	1.4	1.2	1.4	1.5	1.1	1.2	1.3
Risk taking	0.9	1.3	3.8	1.1	0.9	1.1	1.8	0.9	0.7	0.7	0.5	0.4	1.6	1.3	0.6	1.0	1.0	1.9	1.6
Fractured/broken bones in last 5 years	0.9	1.1	2.3	-1.0	-1.2	-0.6	-0.5	-1.1	-1.4	-1.2	-1.3	-1.4	-0.6	-0.6	-1.4	-1.0	-1.5	-0.5	-0.6
Waist Hip Ratio (WHR)	0.8	3.7	11.1	-1.5	-1.9	-2.1	-0.5	-1.6	-2.0	-1.7	-2.1	-1.9	-1.0	-0.6	-2.2	-1.9	-3.3	-3.1	-0.7
Illnesses of mother	0.8	1.0	1.9	1.0	1.1	1.4	0.8	1.0	1.2	0.9	1.1	1.1	0.7	0.7	1.1	1.2	1.2	-0.1	0.7
Had major operations	0.8	1.0	2.0	-1.1	-1.0	-1.0	-0.7	-0.9	-1.2	-0.8	-1.0	-1.0	-0.8	-0.7	-1.1	-1.4	-1.4	0.1	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.3	1.1	1.0	0.7	1.0	1.0	1.0	1.0	0.9	0.8	0.9	1.1	1.0	0.9	1.0	0.5	1.0
Smoking status: Current	0.8	1.2	2.5	-1.0	-1.1	-0.8	-0.1	-1.1	-1.3	-1.2	-1.3	-1.2	-0.4	-1.6	-1.4	-1.4	-1.0	-1.0	-0.1
Medication: Atorvastatin	0.8	1.0	2.5	-0.7	-1.1	-1.2	0.4	-1.1	-1.2	-0.3	-1.6	-1.6	-0.1	-0.9	-1.4	-0.9	-0.5	0.9	0.3
Depression (Nagel 2018)	0.7	1.1	2.3	-1.1	-1.2	-0.3	-1.0	-1.1	-1.3	-0.9	-1.2	-1.5	-0.8	-0.9	-1.3	-1.3	-1.2	0.1	-1.0
Prostate Cancer	0.7	0.9	2.2	-0.7	-1.1	-1.5	-0.1	-0.8	-1.1	-0.8	-1.3	-0.8	-0.3	-0.7	-1.1	-1.3	-1.0	-1.3	-0.2
Mean Putamen Volume	0.7	0.9	1.4	-1.0	-1.0	-0.2	-0.8	-0.9	-1.1	-1.0	-0.9	-1.1	-0.5	-0.9	-1.0	-0.8	-1.2	-1.1	-0.8
Hair/balding pattern: Pattern 2	0.7	0.9	2.9	-1.0	-1.0	-1.7	-0.8	-0.9	-0.9	-0.5	-0.8	-0.9	-1.0	-0.5	-0.9	-1.0	-1.0	0.3	-0.9
Noisy workplace	0.7	0.8	2.1	0.6	1.0	0.8	-0.4	0.9	1.2	1.0	1.4	1.1	-0.1	0.8	1.4	1.0	0.9	0.3	-0.2
Mouth/teeth dental problems: Dentures	0.7	1.1	2.9	-1.2	-1.1	-0.8	-1.1	-1.0	-1.0	-1.0	-0.8	-0.6	-1.2	-1.7	-0.9	-1.0	-0.8	-1.1	-1.3
Depression (self-reported)	0.7	0.8	2.9	0.9	0.7	1.1	1.2	0.8	0.7	0.5	0.6	0.4	1.0	1.2	0.6	0.7	0.6	1.7	1.0
Tense / ‘highly strung’	0.7	1.2	2.6	-1.2	-1.1	-1.2	-0.9	-1.1	-1.1	-1.0	-1.1	-1.1	-1.1	-0.5	-1.2	-1.1	-1.6	-0.9	-1.0
Birth weight	0.7	1.4	3.2	-1.2	-1.1	-0.9	-1.5	-1.1	-0.9	-1.2	-0.8	-1.0	-1.4	-1.1	-0.9	-0.7	-1.8	-1.3	-1.4
Osteoporosis (self-reported)	0.7	0.9	1.9	0.9	0.9	0.8	0.8	0.9	1.0	1.0	0.8	1.4	0.6	1.4	0.9	0.9	1.1	0.2	0.8
Crohns Disease (2017)	0.6	1.4	3.3	-1.1	-1.2	-1.2	0.2	-1.1	-1.6	-0.9	-1.5	-1.8	-0.2	-1.2	-1.7	-1.2	-1.2	0.1	0.2
HbA1C	0.6	0.7	1.5	-0.6	-0.9	-0.6	-0.8	-1.0	-0.6	-0.8	-1.2	-0.9	-0.8	-0.4	-0.8	-0.8	-0.8	-0.8	-0.8
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.1	0.8	0.8	0.8	0.8	0.7	0.8	1.0	0.9	0.7	0.8	0.8	0.7	1.0	0.9	1.1	0.7
Supplements: Zinc	0.6	0.6	1.7	0.6	0.8	0.6	-0.2	0.6	1.0	0.8	1.2	1.3	-0.1	0.7	1.1	0.7	0.5	-0.8	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.1	-0.9	-0.9	-0.8	-0.2	-0.9	-1.2	-1.0	-1.3	-1.5	-0.3	-0.4	-1.3	-1.0	-1.4	0.2	-0.2
Medication: Ibuprofen	0.6	0.7	1.7	-0.9	-0.6	-0.7	-1.3	-0.8	-0.5	-0.4	-0.5	-0.7	-1.1	-1.0	-0.4	-0.5	-1.1	-0.2	-1.3
Leg pain on walking	0.6	0.7	2.4	-0.8	-0.8	-0.8	-0.4	-0.8	-0.9	-0.5	-0.9	-1.1	-0.5	-0.8	-0.9	-0.9	-0.6	1.6	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.1	-1.1	-1.1	-0.7	-0.8	-1.1	-1.1	-0.9	-1.1	-1.2	-1.0	-1.4	-1.1	-1.1	-0.9	0.1	-0.9
Breast Cancer	0.5	1.2	2.9	1.2	1.1	0.6	0.8	1.2	1.2	1.4	1.2	1.4	0.9	1.7	1.2	0.9	0.6	-0.9	0.8
Ovarian Cancer	0.5	0.6	3.1	0.7	0.8	1.8	0.6	0.7	0.7	0.2	0.7	0.3	0.9	0.3	0.8	0.8	1.1	0.5	0.6
Systolic Blood Pressure	0.5	2.4	4.4	-1.6	-1.7	-1.6	-1.5	-1.5	-1.5	-1.2	-1.6	-0.8	-1.7	-1.5	-1.5	-1.8	-1.6	-2.1	-1.4
Hypothyroidism (self reported)	0.5	1.0	2.2	-0.8	-1.1	-1.5	-0.0	-1.1	-1.1	-1.1	-1.4	-1.1	-0.5	-0.6	-1.4	-0.9	-1.2	-0.9	-0.2
Lung FEV1/FVC ratio	0.5	2.5	5.1	-1.7	-1.8	-0.8	-0.9	-1.8	-1.9	-2.3	-2.0	-1.9	-1.2	-1.7	-2.0	-1.5	-1.1	-0.5	-1.2
Maternal smoking around birth	0.5	0.8	1.2	-1.1	-0.9	0.0	-1.1	-1.0	-0.9	-1.0	-0.7	-0.9	-1.0	-0.6	-0.9	-0.7	-0.9	-0.3	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.0	2.4	-1.2	-1.0	-0.6	-1.5	-1.0	-0.9	-0.7	-0.6	-0.1	-1.5	-1.0	-0.8	-1.1	-0.5	-1.1	-1.5
Lung cancer (father)	0.5	0.6	1.7	-0.7	-0.7	-0.6	-0.3	-0.7	-0.9	-0.5	-0.8	-1.3	-0.3	-0.7	-0.9	-0.7	-1.0	1.0	-0.3
Pulse wave Arterial Stiffness index	0.5	0.5	2.5	-0.7	-0.5	0.7	-0.5	-0.6	-0.6	-0.8	-0.6	-0.9	-0.3	-0.3	-0.6	-0.2	-0.9	1.6	-0.6
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.3	0.6	0.5	0.5	0.8	0.7	0.4	1.1	0.4	0.5	0.8	0.8	0.4	1.0	0.5	1.5	0.8
Pulse rate, automated reading	0.5	1.5	3.8	-1.1	-1.2	-1.0	-0.9	-1.2	-1.2	-2.0	-1.2	-0.9	-1.0	-1.1	-1.1	-1.4	-0.8	-1.9	-1.0
Mood swings	0.5	0.9	2.9	-1.0	-0.8	0.0	-1.7	-0.8	-0.5	-1.0	-0.4	-0.3	-1.6	-0.5	-0.3	-0.6	-1.1	-0.2	-1.6
Qualifications: nursing, teaching	0.5	0.8	1.9	1.0	0.9	0.3	1.3	1.0	0.7	0.7	0.8	0.4	1.4	0.2	0.6	0.6	0.7	1.1	1.3
Commuting to job workplace: Public transport	0.5	0.6	1.0	0.9	0.8	-0.1	0.6	0.9	0.9	0.8	0.7	1.0	0.7	0.7	1.0	0.8	0.6	0.0	0.6
Medication: Paracetamol	0.5	0.8	1.6	-0.9	-0.9	-1.1	-0.8	-0.9	-0.9	-0.7	-0.9	-0.9	-0.8	-0.9	-0.8	-0.8	-1.3	-0.4	-0.8
Medication: Lisinopril	0.5	0.6	4.7	0.5	0.5	0.8	0.9	0.4	0.3	0.1	0.2	-0.2	1.1	-0.0	0.1	0.6	0.5	2.2	1.0
Basal cell carcinoma (self-reported)	0.5	0.6	1.9	0.7	0.9	1.4	0.1	0.7	1.0	0.4	1.1	1.0	0.4	0.4	1.0	0.9	0.5	0.4	0.2
Irritable Bowel Disease (IBD)	0.4	0.9	2.2	-0.7	-0.9	-0.7	0.7	-0.8	-1.2	-1.0	-1.2	-1.5	0.3	-0.7	-1.5	-0.9	-0.9	0.2	0.6
Hand grip strength (left)	0.4	1.0	5.1	-0.5	-0.7	-1.8	0.2	-0.5	-0.8	-0.7	-0.8	-0.8	-0.0	0.1	-0.9	-0.6	-2.3	-1.7	0.1
Hearing difficulty/problems: Yes	0.4	0.7	2.5	0.7	0.4	-0.7	1.6	0.5	0.3	0.4	-0.1	-0.1	1.3	0.9	-0.1	0.1	0.3	1.2	1.5
Systolic blood pressure, automated reading	0.4	1.1	2.3	-1.0	-1.3	-1.3	-0.2	-1.1	-1.3	-0.7	-1.5	-1.0	-0.5	-1.2	-1.5	-1.3	-0.7	-0.5	-0.2
Medication: Levothyroxine sodium	0.4	0.7	1.3	-0.8	-0.9	-0.9	-0.5	-1.0	-0.8	-1.2	-1.0	-0.7	-0.7	-0.7	-1.0	-0.8	-1.1	-0.7	-0.5
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.6	-0.7	-0.8	-0.8	-0.6	-0.7	-0.8	-0.6	-0.9	-0.9	-0.7	-1.3	-0.7	-0.5	-0.5	0.2	-0.6
Wheeze or whistling in the chest in last year	0.4	0.8	2.2	-0.8	-0.9	-1.5	-0.3	-0.8	-0.9	-0.8	-0.9	-1.0	-0.5	-0.7	-1.0	-1.1	-1.1	-0.3	-0.3
Neck or shoulder pain in last month	0.4	0.6	1.8	-0.7	-0.8	-1.3	-0.2	-0.8	-0.8	-0.7	-1.0	-0.7	-0.5	-0.8	-0.9	-0.8	-0.9	-0.6	-0.4
Medication: Seretide 50 evohaler	0.4	0.5	0.9	0.7	0.6	1.0	0.5	0.7	0.8	0.6	0.7	0.7	0.5	0.8	0.8	0.7	0.6	0.5	0.6
Ever taken oral contraceptive pill	0.4	0.5	1.3	0.4	0.6	0.2	-0.5	0.6	0.8	0.9	1.1	1.0	-0.4	0.5	0.9	0.8	0.3	0.4	-0.4
Hearing aid user	0.4	0.4	1.0	-0.8	-0.6	0.6	-1.0	-0.6	-0.5	-0.7	-0.5	-0.7	-0.8	-0.1	-0.5	-0.5	-0.7	0.6	-1.0
Schizophrenia (2018)	0.3	0.7	3.6	-0.7	-0.6	-0.5	-0.7	-0.6	-0.5	-0.7	-0.4	-0.3	-1.0	-1.1	-0.4	-0.7	-1.0	-1.9	-0.7
Coronary Artery Disease (CAD)	0.3	0.3	1.7	-0.5	-0.3	-0.3	-1.3	-0.3	-0.0	-0.3	-0.0	-0.1	-0.9	-0.2	0.3	-0.3	-0.7	-0.1	-1.0
Crohns Disease (2012)	0.3	0.5	1.2	-0.8	-0.8	-0.9	-0.0	-0.7	-1.0	-0.4	-0.8	-0.9	-0.4	-0.8	-1.1	-0.8	-0.7	-0.2	-0.0
Neuroticism (2016)	0.3	0.4	1.4	0.4	0.3	-0.6	1.2	0.4	0.0	0.1	-0.2	-0.1	1.0	0.3	-0.1	-0.2	0.1	1.0	1.2
Allergy or Eczema	0.3	0.7	6.6	0.2	-0.1	-0.8	0.8	-0.1	-0.2	-0.2	-0.5	-0.8	0.8	-0.2	-0.4	-0.0	0.3	2.6	0.8
Average weekly spirits intake	0.3	0.4	1.0	0.6	0.6	0.4	0.5	0.6	0.7	0.9	0.6	1.0	0.3	0.4	0.6	0.6	0.5	-0.4	0.4
Severe depression (siblings)	0.3	0.4	1.5	-0.3	-0.4	-1.2	0.3	-0.5	-0.5	-0.2	-0.7	-0.8	0.1	-0.4	-0.7	-0.5	-0.5	-1.1	0.3
Hand grip strength (right)	0.3	0.7	3.9	-0.2	-0.5	-1.6	0.6	-0.3	-0.6	-0.7	-0.6	-0.6	0.3	0.3	-0.7	-0.6	-2.0	-1.4	0.6
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.8	-0.3	-0.6	-1.3	0.5	-0.6	-0.7	-0.7	-1.0	-1.2	0.3	-0.5	-0.9	-0.5	-0.2	2.0	0.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.8	-0.5	-0.6	-0.4	-0.0	-0.6	-0.7	-0.7	-0.8	-0.9	-0.2	-0.4	-0.7	-0.6	-0.4	-0.9	0.0
Nervous feelings	0.3	0.5	1.0	-0.6	-0.6	-1.0	0.2	-0.6	-0.8	-0.8	-0.9	-1.0	0.0	-0.9	-1.0	-0.9	-0.8	-0.6	0.1
Forced vital capacity (FVC)	0.3	1.2	2.5	1.2	1.2	1.0	1.4	1.1	0.9	0.2	1.1	0.5	1.5	1.6	0.8	1.0	0.1	1.0	1.4
Financial difficulties in last 2 years	0.3	0.5	1.9	-0.6	-0.5	-0.5	-0.4	-0.5	-0.6	-0.8	-0.5	-0.7	-0.6	-0.7	-0.6	-0.4	-0.8	-1.4	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.5	-0.6	-0.3	-0.1	-1.2	-0.5	-0.2	-0.1	-0.1	-0.4	-0.9	-0.7	0.0	-0.2	-0.5	0.6	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.6	-0.6	-0.6	-0.3	-0.3	-0.6	-0.6	-0.8	-0.7	-0.8	-0.4	-0.3	-0.6	-0.8	-1.2	-0.7	-0.4
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.1	0.8	0.8	0.3	0.6	0.8	0.7	1.0	0.7	0.6	0.7	-0.0	0.7	0.8	0.7	-0.0	0.7
Glaucoma (self-reported)	0.3	0.4	1.1	0.7	0.7	0.1	0.7	0.6	0.7	0.6	0.5	0.5	0.6	1.0	0.5	0.7	0.0	0.6	0.6
Pulse wave peak to peak time	0.3	0.4	4.0	0.3	0.1	-1.3	0.3	0.1	0.2	0.3	0.1	0.5	0.1	0.1	0.1	-0.2	0.1	-2.0	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	3.4	-0.2	-0.3	-0.6	-0.1	-0.4	-0.3	-0.6	-0.5	-0.5	-0.1	-0.3	-0.3	-0.6	-0.0	1.8	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	3.8	-0.2	-0.0	-0.6	-0.4	-0.1	0.0	0.3	0.1	0.2	-0.4	0.1	0.1	-0.2	-0.1	-2.0	-0.4
Loneliness, isolation	0.3	0.4	1.0	0.6	0.6	0.8	0.2	0.6	0.7	0.9	0.7	0.6	0.3	1.0	0.7	0.5	0.6	0.9	0.3
Bipolar Disorder or Schizophrenia	0.2	0.4	1.1	0.7	0.6	0.7	0.9	0.7	0.5	0.5	0.4	0.6	0.9	0.1	0.6	0.8	0.2	0.2	1.0
Blood Red Count	0.2	1.5	3.4	1.2	1.2	0.8	1.4	1.3	1.0	1.8	0.9	0.5	1.5	1.2	0.9	1.3	1.1	1.4	1.3
Respiratory disease	0.2	0.5	3.9	0.4	0.4	-0.4	0.7	0.4	0.2	0.7	0.2	-0.4	0.8	0.5	0.1	0.4	0.1	2.0	0.7
Sensitivity / hurt feelings	0.2	0.3	1.3	0.3	0.0	0.0	1.1	0.1	-0.3	-0.1	-0.4	-0.6	1.0	-0.0	-0.4	-0.2	0.1	1.0	1.1
Chronic bronchitis/emphysema (father)	0.2	0.3	1.1	-0.4	-0.4	-0.7	-0.2	-0.3	-0.5	-0.7	-0.5	-0.5	-0.3	0.2	-0.5	-0.5	-1.0	-0.7	-0.3
Number of incorrect matches in round	0.2	0.4	1.1	-0.5	-0.7	-0.5	0.3	-0.6	-0.9	-0.5	-1.0	-1.0	0.2	-0.5	-0.9	-0.7	-0.6	0.0	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.6	-0.7	-0.8	-0.8	-0.6	-0.6	-0.7	-0.0	-0.7	-0.2	-0.8	-0.6	-0.7	-0.7	-0.2	-0.4	-0.6
Allergy	0.2	0.5	2.7	0.2	0.5	1.1	-0.5	0.4	0.6	0.6	0.7	1.0	-0.2	0.9	0.8	0.3	0.4	-1.6	-0.4
Falls in the last year	0.2	0.3	1.3	0.4	0.0	-0.2	1.2	0.1	-0.1	-0.7	-0.3	-0.3	0.8	0.1	-0.4	-0.0	-0.5	0.1	1.0
Number of live births	0.2	0.2	0.9	0.3	0.4	0.9	-0.1	0.2	0.5	0.3	0.5	0.7	-0.0	0.6	0.6	0.4	0.6	-0.2	-0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.9	-0.4	-0.6	-1.0	0.1	-0.6	-0.6	-0.7	-0.8	-0.4	-0.3	-0.2	-0.7	-0.5	-0.8	-0.5	0.1
Medication: Amlodipine	0.2	0.3	1.2	-0.5	-0.4	0.1	-1.1	-0.4	-0.0	-0.2	-0.2	0.4	-1.1	0.1	0.2	-0.0	-0.5	-0.8	-1.0
Forced vital capacity (FVC), Best measure	0.2	0.6	1.8	0.8	0.7	0.4	1.3	0.7	0.4	-0.3	0.5	-0.1	1.3	1.3	0.3	0.4	-0.3	0.5	1.4
Health satisfaction	0.2	0.3	0.5	-0.5	-0.6	-0.6	-0.4	-0.6	-0.6	-0.2	-0.6	-0.7	-0.5	-0.4	-0.6	-0.6	-0.3	-0.6	-0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.6	-0.4	-0.6	-0.6	-0.2	-0.5	-0.6	-0.6	-0.7	-0.4	-0.2	-0.5	-0.6	-0.4	-0.8	0.4	-0.1
Migraine (self-reported)	0.2	0.3	1.2	-0.1	0.2	0.3	-0.9	0.0	0.5	-0.1	0.5	0.4	-0.7	1.1	0.6	0.1	-0.0	-0.5	-0.8
Heart disease (mother)	0.2	0.3	1.1	0.4	-0.0	-0.5	1.1	0.2	-0.1	-0.0	-0.5	-0.2	1.0	0.5	-0.3	-0.0	0.0	-0.5	1.1
Ever had bowel cancer screening	0.2	0.3	0.7	-0.2	-0.5	-0.7	0.6	-0.5	-0.5	-0.3	-0.7	-0.2	0.1	0.0	-0.8	-0.6	-0.2	-0.8	0.4
Eye problems/disorders: Cataract	0.2	0.2	0.9	-0.2	-0.2	0.3	-0.8	-0.3	0.1	-0.4	0.2	-0.1	-0.7	-0.5	0.2	-0.2	0.3	0.5	-0.9
Breast cancer (self-reported)	0.2	0.3	1.1	-0.6	-0.4	0.5	-1.0	-0.4	-0.3	-0.6	-0.2	-0.2	-0.8	0.0	-0.2	-0.4	-0.3	0.1	-1.1
Depressed Affect (Nagel 2018)	0.1	0.3	1.0	-0.6	-0.4	0.2	-1.0	-0.5	-0.3	-0.3	-0.2	-0.4	-0.8	-0.0	-0.2	-0.4	-0.4	0.7	-1.0
Neuroticism (Nagel 2018)	0.1	0.2	0.6	0.0	-0.2	-0.7	0.7	-0.1	-0.3	0.1	-0.6	-0.4	0.5	0.3	-0.4	-0.4	-0.4	0.2	0.7
Alzheimer’s Disease (in father)	0.1	0.1	0.4	0.2	0.2	-0.3	0.6	0.1	0.0	-0.0	-0.0	-0.0	0.4	-0.2	-0.1	0.1	0.2	0.1	0.6
Ulcerative Colitis (UC)	0.1	0.2	0.7	0.1	-0.1	0.2	0.8	-0.1	-0.3	-0.4	-0.2	-0.6	0.7	0.1	-0.5	-0.0	-0.3	0.3	0.7
Primary Biliary Cirrhosis	0.1	0.2	0.6	-0.5	-0.2	0.4	-0.5	-0.2	-0.3	-0.8	0.0	-0.2	-0.4	0.1	-0.3	-0.1	-0.5	-0.4	-0.6
Schizophrenia (2014)	0.1	0.2	1.7	-0.2	-0.0	-0.2	-0.5	-0.0	0.1	0.1	0.2	0.3	-0.7	-0.5	0.2	-0.1	-0.5	-1.3	-0.4
Blood Eosinophil Count	0.1	0.7	4.0	0.7	0.6	-0.4	0.8	0.7	0.7	0.7	0.5	0.6	0.7	1.4	0.6	0.7	0.3	2.0	0.8
Neuroticism	0.1	0.2	0.4	0.2	0.2	0.5	0.6	0.3	0.1	0.6	-0.0	-0.2	0.5	0.6	-0.0	0.3	-0.2	0.7	0.5
Fed-up feelings	0.1	0.2	1.5	0.0	-0.1	0.2	0.4	-0.0	-0.2	-0.2	-0.3	-0.5	0.2	0.5	-0.3	-0.1	-0.1	1.2	0.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.4	-0.4	-0.2	-0.0	-0.6	-0.4	-0.1	-0.5	-0.0	-0.1	-0.6	0.3	-0.1	-0.2	-0.4	-0.2	-0.7
Worrier / anxious feelings	0.1	0.1	0.4	0.1	0.1	-0.4	0.6	0.2	-0.0	0.6	-0.1	0.1	0.2	-0.1	-0.2	0.1	-0.4	-0.5	0.7
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.6	0.4	0.4	0.8	0.7	0.4	0.2	-0.5	0.4	-0.1	0.8	0.8	0.1	0.4	-0.3	0.5	0.7
Pulse rate	0.1	0.2	1.0	-0.3	-0.2	1.0	-0.8	-0.3	-0.1	-0.5	0.0	-0.0	-0.5	-0.1	0.1	-0.0	0.2	-0.5	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.6	0.3	0.2	0.3	0.7	0.2	-0.1	-0.8	0.1	-0.4	0.7	0.7	-0.2	0.0	-0.3	0.1	0.7
Length of working week for main job	0.1	0.1	0.8	-0.1	-0.2	-0.5	0.2	-0.2	-0.3	-0.5	-0.4	-0.5	0.1	-0.1	-0.4	-0.4	-0.1	0.9	0.2
Hair/balding pattern: Pattern 4	0.1	0.2	1.0	0.2	0.3	0.4	-0.5	0.3	0.5	-0.1	0.6	1.0	-0.4	-0.4	0.7	0.2	0.2	-0.1	-0.3
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.2	0.1	-0.1	-0.4	0.4	0.0	-0.1	-0.3	-0.3	0.1	0.2	0.4	-0.2	0.0	-0.3	-0.5	0.2
Number of full brothers	0.1	0.2	0.6	0.4	0.3	0.2	0.8	0.4	0.2	0.1	0.1	0.1	0.6	-0.2	0.1	0.5	0.1	0.7	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.5	0.1	0.2	0.7	-0.2	0.1	0.3	-0.1	0.4	-0.0	-0.2	0.6	0.3	0.1	-0.1	0.3	-0.3
Number of children fathered	0.1	0.1	0.5	0.2	0.2	-0.5	0.5	0.2	0.2	0.7	0.1	0.4	0.3	-0.1	0.1	0.0	0.4	0.1	0.5
Handedness (chirality/laterality): Left-handed	0.1	0.1	1.0	-0.1	-0.0	0.5	0.0	-0.1	-0.1	-0.4	-0.2	-0.7	0.1	0.3	-0.1	0.0	-0.4	1.0	-0.2
Miserableness	0.1	0.1	0.7	-0.1	0.0	0.9	-0.3	-0.0	0.1	-0.4	0.2	0.1	-0.3	-0.4	0.2	-0.1	0.2	0.8	-0.3
Myopia	0.1	0.1	0.6	0.4	0.3	0.5	0.7	0.4	0.1	-0.2	-0.0	0.2	0.6	0.3	0.0	0.3	0.3	0.0	0.6
Supplements: Calcium	0.1	0.1	0.6	0.3	0.3	-0.4	0.5	0.3	0.3	0.7	0.1	0.6	0.3	0.4	0.2	0.3	0.2	-0.2	0.4
Hair Pigment	0.0	0.6	1.6	-0.8	-0.9	-0.6	-0.5	-0.8	-1.0	-0.8	-0.9	-1.3	-0.6	-0.6	-1.0	-0.6	-0.9	-0.4	-0.7
Tanning	0.0	0.2	0.7	0.4	0.3	-0.5	0.5	0.3	0.4	0.3	0.2	0.5	0.4	-0.0	0.3	0.2	0.8	0.8	0.5
Neuroticism score	0.0	0.1	0.2	-0.1	-0.3	-0.3	0.4	-0.2	-0.3	-0.2	-0.4	-0.3	0.0	-0.1	-0.4	-0.4	-0.4	0.3	0.3
Peak expiratory flow (PEF)	0.0	0.1	0.2	0.3	0.2	0.1	0.5	0.2	0.0	-0.1	0.1	-0.0	0.5	-0.1	0.0	0.1	0.1	0.4	0.4
Eye problems/disorders: None of the above	0.0	0.0	0.2	-0.2	-0.2	-0.2	-0.1	-0.1	-0.2	-0.2	-0.1	-0.1	0.0	-0.1	-0.3	-0.0	-0.4	-0.1	-0.1
Mean time to correctly identify matches	0.0	0.1	0.6	0.0	0.0	-0.3	-0.0	0.0	0.1	0.3	-0.1	0.2	-0.1	0.2	0.1	0.2	-0.0	-0.8	-0.1

Hub : Genes

C18orf8

Models

Trait associations