Best TWAS P=2.07e-10 · Best GWAS P=2.78e-09 conditioned to 0.597
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | TRAF3IP3 | 0.28 | 0.17 | lasso | 5 | 0.18 | 2.6e-05 | -5.9 | 5.7 | 1.5e-08 | -0.88 | 0.02 | 0.92 | FALSE |
| 2 | GTEx | Whole Blood | TRAF3IP3 | 0.21 | 0.03 | enet | 23 | 0.11 | 2.0e-10 | 3.7 | 6.3 | 3.4e-10 | -0.59 | 0.10 | 0.90 | FALSE |
| 3 | METSIM | Adipose | TRAF3IP3 | 0.04 | 0.01 | blup | 491 | 0.01 | 6.3e-03 | -5.8 | 5.9 | 2.9e-09 | -0.65 | 0.02 | 0.94 | FALSE |
| 4 | NTR | Blood | TRAF3IP3 | 0.05 | 0.04 | lasso | 10 | 0.05 | 1.7e-16 | -5.3 | 5.3 | 1.4e-07 | -0.86 | 0.09 | 0.91 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TRAF3IP3 | 0.02 | 0.00 | blup | 86 | 0.01 | 1.0e-02 | -5.5 | 6.4 | 2.1e-10 | -0.90 | 0.02 | 0.63 | TRUE |