[Hub]/) : Traits : Blood White Count : ← →

chr1:206,194,087-208,664,733

Best TWAS P=3e-29 · Best GWAS P=4.98e-29 conditioned to 0

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Cells EBV-transformed lymphocytes	CD46	0.33	0.25	lasso	4	0.24	3.2e-08	-10.9	11.2	3.0e-29	-0.86	0.02	0.98	TRUE
3	GTEx	Adipose Visceral Omentum	CD46	0.11	0.02	lasso	2	0.03	1.0e-02	-10.9	11.2	3.3e-29	-0.81	0.03	0.86	TRUE
2	GTEx	Adipose Subcutaneous	CD46	0.07	0.05	lasso	3	0.03	7.9e-04	-10.9	10.4	2.7e-25	-0.83	0.03	0.97	TRUE
13	GTEx	Ovary	CD46	0.21	0.08	enet	11	0.12	7.0e-04	-5.9	8.5	2.7e-17	-0.63	0.07	0.64	TRUE
12	GTEx	Nerve Tibial	PFKFB2	0.08	0.00	lasso	4	0.00	8.8e-01	-6.3	-6.2	4.0e-10	-0.02	0.02	0.72	TRUE
20	The Cancer Genome Atlas	Thyroid Carcinoma	CD46	0.03	0.03	enet	3	0.03	6.9e-04	-6.0	-5.7	1.0e-08	0.44	0.17	0.12	TRUE
14	METSIM	Adipose	CD55	0.07	0.05	blup	366	0.06	1.7e-09	2.1	5.7	1.4e-08	-0.04	1.00	0.00	TRUE
15	METSIM	Adipose	EIF2D	0.13	0.07	bslmm	353	0.09	3.8e-13	-3.5	-5.3	1.0e-07	0.03	1.00	0.00	TRUE
9	GTEx	Esophagus Muscularis	CD46	0.37	0.27	lasso	12	0.28	1.5e-17	-11.0	11.1	9.8e-29	-0.93	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	CD46	0.10	0.12	lasso	4	0.12	5.6e-14	-11.0	11.0	2.2e-28	-0.88	0.00	1.00	FALSE
7	GTEx	Colon Sigmoid	CD46	0.29	0.23	lasso	2	0.21	7.6e-08	-10.9	11.0	5.5e-28	-0.88	0.02	0.98	FALSE
10	GTEx	Heart Atrial Appendage	CD46	0.12	0.10	enet	6	0.10	1.9e-05	-10.9	10.9	8.0e-28	-0.88	0.03	0.95	FALSE
5	GTEx	Artery Tibial	CD46	0.27	0.35	lasso	4	0.34	9.0e-28	-10.8	10.8	2.4e-27	-0.88	0.05	0.95	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CD46	0.14	0.16	bslmm	499	0.16	3.4e-19	-11.0	10.8	4.0e-27	-0.87	0.02	0.98	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	CD46	0.29	0.24	lasso	4	0.22	2.1e-08	-10.9	10.6	4.5e-26	-0.85	0.02	0.98	FALSE
4	GTEx	Artery Aorta	CD46	0.20	0.18	enet	11	0.20	2.5e-11	-10.8	10.5	8.0e-26	-0.84	0.03	0.97	FALSE
11	GTEx	Nerve Tibial	CD46	0.24	0.15	lasso	6	0.20	2.1e-14	-5.9	8.8	9.4e-19	-0.73	0.69	0.31	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PFKFB2	0.06	0.01	blup	57	0.04	5.1e-05	4.4	-5.4	7.7e-08	-0.09	0.03	0.96	FALSE
18	The Cancer Genome Atlas	Brain Lower Grade Glioma	CR1	0.07	0.06	lasso	3	0.06	6.4e-07	-5.3	-5.3	1.1e-07	0.16	0.00	1.00	FALSE
19	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C4BPA	0.11	0.00	blup	49	0.05	3.2e-03	1.7	-5.2	2.2e-07	0.04	0.01	0.38	FALSE