Best TWAS P=3.64e-11 · Best GWAS P=9.29e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | DOK6 | 0.18 | 0.18 | lasso | 5 | 0.18 | 3.2e-56 | 6.5 | 6.6 | 3.6e-11 | 0.98 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CD226 | 0.04 | 0.04 | enet | 7 | 0.05 | 5.3e-10 | 6.5 | -5.9 | 2.9e-09 | -0.92 | 0.00 | 1.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD226 | 0.09 | 0.03 | blup | 76 | 0.06 | 1.7e-07 | 6.5 | -6.6 | 4.1e-11 | -0.84 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CD226 | 0.03 | 0.01 | enet | 7 | 0.02 | 4.3e-03 | 2.0 | -5.3 | 1.2e-07 | -0.53 | 0.02 | 0.61 | FALSE |