Best TWAS P=4.04e-10 · Best GWAS P=7.26e-11 conditioned to 0.00291
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Caudate basal ganglia | AC139100.3 | 0.17 | 0.04 | enet | 10 | 0.10 | 0.00103 | 3.5 | 6.3 | 4.0e-10 | 0.59 | 0.03 | 0.76 | TRUE |
2 | GTEx | Brain Cerebellar Hemisphere | PQLC1 | 0.31 | 0.01 | lasso | 9 | 0.14 | 0.00025 | -3.7 | 5.3 | 9.3e-08 | 0.30 | 0.04 | 0.53 | TRUE |
3 | GTEx | Esophagus Gastroesophageal Junction | AC139100.3 | 0.16 | 0.10 | enet | 16 | 0.10 | 0.00017 | -4.6 | 5.3 | 1.2e-07 | 0.22 | 0.24 | 0.08 | FALSE |