TWAS hub - ZNF496

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2380	0.0500	1.3e-08	0.123	NA	0.140	NA	0.142	3.2e-10	NA	1.6e-11	NA	1.1e-11
2	GTEx	Artery Aorta	0.2050	0.0540	1.8e-04	0.128	NA	0.163	NA	0.173	1.5e-07	NA	2.7e-09	NA	7.9e-10
3	GTEx	Artery Tibial	0.1439	0.0441	3.4e-04	0.114	NA	0.109	NA	0.115	3.4e-09	NA	7.5e-09	NA	2.6e-09
4	GTEx	Brain Cerebellum	0.2590	0.0940	9.0e-03	0.127	NA	0.124	NA	0.117	1.4e-04	NA	1.7e-04	NA	2.5e-04
5	GTEx	Brain Frontal Cortex BA9	0.3930	0.1092	1.4e-03	-0.004	NA	0.045	NA	0.044	4.4e-01	NA	2.4e-02	NA	2.6e-02
6	GTEx	Breast Mammary Tissue	0.1520	0.0560	9.6e-03	0.159	NA	0.120	NA	0.129	1.4e-08	NA	9.5e-07	NA	4.0e-07
7	GTEx	Breast Mammary Tissue (Female)	0.1890	0.0942	5.9e-02	0.108	NA	0.026	NA	0.095	4.1e-04	NA	5.8e-02	NA	9.0e-04
8	GTEx	Cells Transformed fibroblasts	0.1660	0.0450	5.3e-05	0.116	NA	0.091	NA	0.115	5.3e-09	NA	2.5e-07	NA	6.0e-09
9	GTEx	Esophagus Muscularis	0.3010	0.0660	5.6e-06	0.160	NA	0.155	NA	0.155	6.1e-10	NA	1.0e-09	NA	1.1e-09
10	GTEx	Lung	0.2378	0.0471	1.6e-09	0.245	NA	0.218	NA	0.232	9.7e-19	NA	1.2e-16	NA	1.1e-17
11	GTEx	Nerve Tibial	0.2928	0.0519	5.9e-10	0.240	NA	0.243	NA	0.267	5.4e-17	NA	3.2e-17	NA	5.2e-19
12	GTEx	Pancreas	0.2700	0.0790	1.6e-03	0.199	NA	0.182	NA	0.198	8.0e-09	NA	3.9e-08	NA	9.1e-09
13	GTEx	Skin Sun Exposed Lower leg	0.1320	0.0350	3.3e-05	0.115	NA	0.136	NA	0.124	9.8e-10	NA	2.4e-11	NA	2.1e-10
14	GTEx	Spleen	0.3120	0.0970	5.2e-03	0.348	NA	0.274	NA	0.325	9.1e-10	NA	9.7e-08	NA	4.1e-09
15	GTEx	Thyroid	0.2610	0.0540	7.5e-08	0.181	NA	0.197	NA	0.193	8.0e-14	NA	5.2e-15	NA	9.8e-15
16	METSIM	Adipose	0.1259	0.0270	1.3e-12	0.130	0.083	0.108	0.105	0.119	7.3e-19	2.2e-12	7.5e-16	1.9e-15	2.3e-17
17	TCGA	Breast Invasive Carcinoma	0.0269	0.0097	3.8e-08	0.039	0.033	0.038	NA	0.038	1.6e-08	1.8e-07	2.3e-08	NA	2.5e-08
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0750	0.0311	4.0e-07	0.048	0.061	0.047	NA	0.048	3.8e-06	2.0e-07	5.3e-06	NA	3.6e-06
19	TCGA	Brain Lower Grade Glioma	0.0524	0.0195	1.9e-07	0.083	0.059	0.077	NA	0.081	1.1e-09	2.6e-07	4.3e-09	NA	1.9e-09
20	TCGA	Lung Adenocarcinoma	0.0386	0.0210	1.3e-03	0.030	0.014	0.008	NA	0.018	1.7e-04	7.4e-03	3.6e-02	NA	3.2e-03
21	TCGA	Pancreatic Adenocarcinoma	0.1340	0.0670	1.1e-03	0.014	0.084	0.048	NA	0.041	7.9e-02	2.1e-04	4.5e-03	NA	7.9e-03
22	TCGA	Pheochromocytoma and Paraganglioma	0.2040	0.0850	1.2e-04	0.133	0.101	0.118	NA	0.122	5.9e-06	8.2e-05	2.0e-05	NA	1.5e-05
23	TCGA	Prostate Adenocarcinoma	0.0417	0.0191	9.2e-05	0.027	0.043	0.038	NA	0.032	7.0e-04	2.5e-05	7.4e-05	NA	2.4e-04
24	TCGA	Thyroid Carcinoma	0.0480	0.0230	1.5e-04	0.046	0.043	0.045	NA	0.043	2.5e-05	4.2e-05	3.3e-05	NA	4.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Frequency of unenthusiasm / disinterest in last 2 weeks	7.2	9.6	19.4	-3.1	-2.0	-3.1	-3.0	-1.9	-3.2	-3.1	-3.1	-3.5	-3.2	-3.2	-3.5	-3.0	-3.1	-3.1	-3.1	-3.2	-4.4	-3.2	-3.1	-2.5	-3.1	-2.7	-3.4
Depression (Nagel 2018)	4.4	6.6	10.0	-2.7	-1.6	-2.7	-2.8	-1.6	-2.7	-2.7	-2.7	-3.1	-2.4	-2.7	-2.9	-2.3	-2.7	-2.3	-2.6	-2.5	-3.2	-2.6	-2.8	-2.0	-2.7	-2.2	-2.7
Depression (self-reported)	3.8	4.6	7.0	-2.2	-2.2	-2.3	-1.6	-0.9	-2.3	-2.3	-2.3	-2.1	-2.2	-2.3	-2.3	-2.1	-2.3	-2.0	-2.1	-2.2	-2.6	-2.2	-2.3	-1.1	-2.4	-1.8	-2.5
Myopia	3.7	5.4	10.2	2.2	1.6	2.0	1.4	0.5	2.1	1.9	2.1	1.9	2.5	2.2	2.3	2.1	1.9	2.8	2.6	2.7	2.9	2.1	3.2	2.7	3.0	2.2	2.8
Mean Putamen Volume	3.5	4.0	6.2	-2.2	-2.0	-2.2	-2.5	-0.2	-2.2	-2.2	-2.2	-1.0	-2.1	-2.2	-2.2	-1.9	-2.2	-2.1	-2.1	-2.0	-1.4	-2.2	-2.0	-1.9	-2.1	-1.9	-1.8
Time employed in main current job	3.5	4.0	5.3	-2.1	-1.7	-2.2	-2.2	-1.8	-2.3	-2.3	-2.3	-1.5	-2.1	-2.3	-2.3	-1.7	-2.3	-1.9	-2.2	-2.1	-1.8	-2.2	-1.8	-0.8	-2.2	-1.6	-1.6
Chronic bronchitis/emphysema (mother)	3.5	4.1	7.4	2.2	2.3	2.1	1.4	0.7	2.1	2.1	2.1	1.9	2.1	2.1	2.0	1.7	2.1	2.1	2.0	2.0	1.5	2.0	2.0	2.7	2.0	2.6	2.3
Blood White Count	3.4	24.9	43.6	5.3	4.4	5.5	5.9	2.1	5.4	5.6	5.4	4.1	5.0	5.3	5.5	6.6	5.6	5.1	4.8	4.7	4.5	5.3	3.6	4.7	3.8	5.2	4.5
Medication: Atorvastatin	3.4	4.2	6.1	-2.0	-2.0	-2.2	-1.3	-1.1	-2.2	-2.2	-2.2	-2.0	-2.1	-2.2	-2.3	-2.1	-2.2	-1.6	-2.3	-2.2	-2.5	-2.2	-2.0	-1.4	-2.2	-1.9	-2.4
Frequency of tiredness / lethargy in last 2 weeks	3.2	5.2	9.8	-2.2	-1.6	-2.2	-1.5	-2.5	-2.2	-2.2	-2.3	-2.6	-2.2	-2.2	-2.5	-1.9	-2.2	-2.1	-2.2	-2.3	-3.1	-2.2	-2.6	-1.6	-2.5	-2.1	-2.7
Lung cancer (father)	3.1	3.6	5.5	-1.8	-1.9	-1.9	-1.3	-1.5	-1.9	-1.8	-1.9	-2.1	-2.0	-1.9	-1.9	-2.4	-1.8	-1.7	-1.9	-1.9	-2.4	-1.9	-1.2	-2.3	-1.4	-2.3	-2.1
Frequency of depressed mood in last 2 weeks	2.8	3.9	8.6	-2.1	-1.3	-2.0	-1.8	-1.1	-2.1	-2.1	-2.1	-1.8	-1.9	-2.1	-2.3	-1.8	-2.1	-1.9	-2.0	-1.9	-2.9	-2.0	-2.1	-1.6	-1.9	-1.7	-2.2
Ever had prostate specific antigen (PSA) test	2.8	3.2	6.7	1.8	1.1	1.9	1.9	1.8	1.9	1.9	1.9	1.3	1.9	1.9	2.1	2.0	1.9	1.8	1.9	1.8	2.6	1.9	1.2	1.6	1.3	1.6	1.8
Stomach or abdominal pain in last month	2.7	3.4	8.5	-2.0	-2.4	-1.9	-0.2	-1.0	-1.9	-1.9	-1.9	-1.0	-1.8	-1.9	-1.7	-1.7	-1.9	-1.6	-1.8	-1.8	-1.6	-1.9	-1.5	-2.5	-1.6	-2.9	-2.3
Qualifications: O levels/GCSEs or equivalent	2.7	4.4	8.9	2.0	1.6	2.0	2.2	1.4	2.0	1.9	2.0	2.1	2.1	2.0	2.2	1.8	1.9	2.4	2.2	2.2	3.0	2.0	2.0	2.0	2.2	1.8	2.4
Alcohol drinker status: Never	2.6	3.1	4.7	1.8	1.6	1.8	1.1	0.4	1.8	1.6	1.8	1.7	2.1	1.9	1.8	1.3	1.6	1.7	2.2	2.2	1.8	1.9	1.9	2.1	1.9	1.9	1.7
Mineral and other dietary supplements	2.5	3.3	6.7	-1.8	-2.6	-2.0	-0.6	-0.8	-2.0	-1.9	-1.9	-1.3	-2.1	-2.0	-1.7	-2.1	-1.9	-2.1	-2.0	-2.0	-1.9	-2.0	-1.5	-1.2	-1.8	-1.7	-1.7
Worry too long after embarrassment	2.4	4.0	9.0	-1.9	-1.2	-2.0	-3.0	-1.6	-2.0	-2.0	-2.0	-2.6	-2.0	-2.0	-2.2	-1.9	-2.0	-1.9	-1.9	-1.9	-2.9	-2.0	-1.6	-0.7	-1.7	-1.4	-1.9
Commuting to job workplace: Walk	2.2	2.4	6.4	1.6	1.5	1.6	1.6	1.5	1.6	1.6	1.5	2.5	1.5	1.5	1.5	0.9	1.6	1.6	1.3	1.5	1.6	1.6	1.6	1.4	1.6	1.4	1.2
Prostate Cancer	2.1	3.0	4.4	-1.9	-1.6	-1.7	-2.0	-1.2	-1.7	-1.7	-1.7	-1.6	-1.7	-1.7	-1.8	-1.3	-1.7	-1.6	-1.7	-1.8	-1.3	-1.7	-1.9	-1.9	-2.0	-2.1	-1.9
Supplements: Glucosamine	2.1	2.7	3.8	1.7	1.7	1.8	1.6	0.9	1.8	1.8	1.8	1.5	1.8	1.8	1.8	1.8	1.8	2.0	1.6	1.7	1.9	1.8	1.2	1.1	1.5	1.4	1.4
Qualifications: A levels/AS levels or equivalent	2.0	4.5	10.8	2.0	0.8	1.9	2.5	1.3	2.0	1.9	2.1	1.6	2.1	2.1	2.3	2.1	1.9	1.8	2.4	2.3	3.3	2.0	2.5	2.0	2.4	1.7	2.4
HbA1C	1.9	2.1	3.4	-1.6	-1.2	-1.6	-1.7	0.0	-1.7	-1.6	-1.6	-1.3	-1.6	-1.6	-1.8	-1.1	-1.6	-1.1	-1.7	-1.6	-1.8	-0.6	-1.4	-0.6	-1.8	-1.1	-1.6
Illnesses of siblings	1.9	2.7	6.8	1.4	1.4	1.6	1.6	2.6	1.6	1.6	1.7	1.0	1.6	1.7	1.7	2.1	1.6	1.6	1.7	1.6	2.2	1.6	1.3	0.5	1.4	1.4	1.9
Medication: Seretide 50 evohaler	1.9	2.2	5.7	1.6	0.8	1.4	2.4	1.2	1.4	1.5	1.4	1.9	1.3	1.4	1.5	1.1	1.5	1.4	1.2	1.4	1.4	1.4	1.5	1.5	1.7	1.3	1.4
Wears glasses or contact lenses	1.9	2.2	5.2	1.4	2.3	1.4	0.1	-0.3	1.4	1.4	1.5	2.1	1.6	1.5	1.2	1.6	1.4	2.0	1.6	1.5	0.6	1.4	1.1	1.6	1.1	2.0	1.7
Ever taken oral contraceptive pill	1.9	2.1	3.4	1.5	1.4	1.4	1.9	1.4	1.4	1.4	1.4	1.0	1.6	1.4	1.4	1.4	1.4	1.6	1.5	1.5	1.1	1.4	1.4	1.4	1.4	1.7	1.3
Heart disease (siblings)	1.9	2.3	4.6	-1.4	-1.5	-1.3	-1.4	-1.7	-1.4	-1.3	-1.4	-1.4	-1.5	-1.4	-1.4	-2.1	-1.3	-2.1	-1.6	-1.5	-1.3	-1.4	-1.4	-1.2	-1.3	-1.9	-1.7
Ever had hysterectomy (womb removed)	1.8	2.1	4.0	-1.6	-1.8	-1.4	-0.7	-0.6	-1.4	-1.4	-1.4	-1.6	-1.3	-1.4	-1.3	-1.5	-1.4	-1.3	-1.3	-1.4	-1.4	-1.4	-1.8	-2.0	-1.5	-1.7	-1.4
Diabetes diagnosed by doctor	1.8	2.9	4.0	1.9	1.3	1.8	2.0	1.9	1.8	1.8	1.8	0.3	1.8	1.8	1.9	2.0	1.8	1.4	1.7	1.8	1.7	1.8	1.6	1.3	2.0	1.5	1.5
Guilty feelings	1.8	2.7	10.2	-1.6	-0.5	-1.5	-3.2	-1.9	-1.5	-1.5	-1.6	-1.5	-1.5	-1.5	-1.8	-1.8	-1.5	-1.0	-1.6	-1.5	-2.5	-1.5	-1.6	-0.3	-1.7	-0.8	-1.7
Neuroticism	1.7	4.2	7.0	-2.0	-1.4	-2.0	-2.6	-2.4	-2.0	-2.1	-2.0	-2.1	-1.9	-2.0	-2.3	-2.5	-2.1	-1.5	-1.9	-1.9	-2.6	-2.0	-2.0	-1.5	-1.8	-1.8	-2.4
Current tobacco smoking	1.7	2.8	8.9	-1.6	-1.8	-1.5	-1.5	-2.5	-1.5	-1.4	-1.5	-0.8	-1.6	-1.5	-1.4	-1.7	-1.4	-1.3	-1.5	-1.7	-0.9	-1.5	-1.9	-3.0	-1.6	-1.9	-1.4
Qualifications: CSEs or equivalent	1.7	2.3	5.3	-1.6	-1.6	-1.3	-0.1	-1.1	-1.3	-1.2	-1.4	-1.6	-1.5	-1.4	-1.3	-1.9	-1.2	-1.4	-1.7	-1.6	-1.2	-1.4	-1.6	-2.3	-1.5	-2.2	-1.7
Loud music exposure frequency	1.7	1.9	3.0	1.3	1.5	1.5	0.5	0.7	1.5	1.4	1.5	0.4	1.7	1.5	1.5	1.4	1.4	1.2	1.6	1.7	0.9	1.5	1.3	1.0	1.4	1.7	1.7
High blood pressure (siblings)	1.7	2.4	5.7	-1.4	-1.5	-1.7	-1.4	-2.4	-1.7	-1.7	-1.7	-0.5	-1.5	-1.7	-1.7	-1.9	-1.7	-1.2	-1.7	-1.4	-2.2	-1.7	-0.8	-0.7	-1.2	-1.0	-1.4
Medication: Allopurinol	1.7	2.3	3.5	1.6	1.6	1.5	1.6	0.4	1.5	1.5	1.5	1.4	1.6	1.5	1.5	1.4	1.5	1.6	1.6	1.6	1.5	1.5	1.9	1.2	1.7	1.7	1.4
Smoking status: Current	1.7	2.7	7.3	-1.7	-1.8	-1.5	-1.5	-2.3	-1.5	-1.5	-1.5	-1.0	-1.6	-1.5	-1.5	-1.7	-1.5	-1.4	-1.6	-1.7	-1.1	-1.5	-1.9	-2.7	-1.6	-1.8	-1.4
Diabetes (self-reported)	1.6	2.5	4.2	1.7	1.1	1.6	2.0	1.8	1.6	1.7	1.6	0.8	1.6	1.6	1.8	1.8	1.7	1.3	1.5	1.6	1.7	1.7	1.6	1.0	1.9	1.3	1.5
Medication: Gliclazide	1.6	1.8	4.0	1.5	1.2	1.4	1.0	0.6	1.4	1.4	1.4	0.1	1.4	1.4	1.4	2.0	1.4	1.2	1.4	1.4	1.7	1.4	1.2	1.7	1.4	1.4	1.2
Number of operations (self-reported)	1.6	2.3	7.7	-1.3	-0.5	-1.2	-2.0	-2.8	-1.2	-1.1	-1.2	-1.0	-1.4	-1.3	-1.4	-1.9	-1.1	-1.0	-1.5	-1.6	-2.0	-1.2	-1.9	-1.1	-2.0	-1.3	-1.8
Alcohol drinker status: Previous	1.6	1.8	2.6	1.4	1.1	1.5	1.2	0.7	1.5	1.4	1.4	1.3	1.6	1.5	1.4	1.4	1.4	1.3	1.5	1.6	1.2	1.5	1.5	0.6	1.4	0.9	1.2
Neuroticism score	1.5	3.2	7.2	-1.7	-1.3	-1.8	-2.0	-2.0	-1.8	-1.8	-1.8	-2.2	-1.7	-1.8	-2.0	-2.1	-1.8	-1.6	-1.7	-1.6	-2.7	-1.8	-1.3	-1.0	-1.4	-1.4	-2.2
Age at last live birth	1.5	2.1	3.4	1.4	0.9	1.4	1.5	0.2	1.4	1.4	1.4	1.7	1.4	1.4	1.7	1.4	1.4	1.5	1.3	1.5	1.7	1.4	1.8	0.8	1.7	1.4	1.9
Commuting to job workplace: Car/motor vehicle	1.5	1.7	2.7	-1.3	-1.6	-1.6	0.1	-1.1	-1.6	-1.7	-1.5	-1.1	-1.4	-1.5	-1.4	-1.5	-1.7	-1.2	-1.2	-1.2	-1.1	-1.5	-0.7	-0.9	-1.0	-1.3	-1.3
Friendships satisfaction	1.5	1.9	3.5	1.5	0.8	1.4	0.9	1.1	1.4	1.3	1.4	0.0	1.7	1.4	1.5	1.4	1.3	1.4	1.6	1.7	1.5	1.4	1.8	0.8	1.9	1.0	1.4
Mouth/teeth dental problems: Mouth ulcers	1.5	2.3	4.5	1.6	1.4	1.7	1.7	1.6	1.7	1.7	1.6	0.9	1.7	1.6	1.5	1.4	1.7	1.4	1.4	1.5	-0.2	1.7	0.9	2.1	1.0	2.1	1.4
Supplements: Fish oil (including cod liver oil)	1.5	2.0	3.9	1.4	1.9	1.4	0.9	0.8	1.4	1.4	1.4	1.3	1.5	1.4	1.3	1.4	1.4	1.7	1.4	1.4	2.0	1.5	0.9	1.2	1.1	1.6	1.5
Smoking Status	1.4	3.4	6.9	-1.8	-1.6	-1.7	-1.2	-2.5	-1.7	-1.6	-1.8	-1.3	-1.8	-1.8	-1.7	-2.3	-1.6	-1.8	-2.0	-2.0	-1.4	-1.8	-2.1	-2.6	-1.8	-1.9	-2.0
Medication for hormone replacement therapy	1.4	1.5	3.2	0.9	1.6	1.2	-0.4	-0.3	1.2	1.2	1.4	1.3	1.4	1.4	1.2	1.1	1.2	1.8	1.7	1.4	1.6	1.3	0.7	0.6	1.1	1.4	1.2
Financial difficulties in last 2 years	1.4	1.8	5.7	-1.2	-0.8	-1.2	-1.1	-2.4	-1.2	-1.2	-1.3	-1.6	-1.2	-1.3	-1.4	-1.3	-1.2	-1.0	-1.3	-1.2	-2.0	-1.2	-1.3	-0.2	-1.4	-1.1	-1.8
Gout (self-reported)	1.4	1.9	3.5	1.4	1.2	1.4	1.3	-1.0	1.4	1.4	1.5	1.0	1.4	1.5	1.4	1.0	1.4	1.9	1.5	1.5	1.2	1.4	1.5	1.1	1.4	1.5	1.1
Medication: Amlodipine	1.4	2.0	6.2	1.3	2.5	1.4	0.4	-0.5	1.4	1.4	1.4	0.3	1.4	1.4	1.1	1.3	1.4	1.4	1.4	1.4	0.7	1.4	0.5	2.5	0.8	2.2	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.9	4.2	-1.2	-1.3	-1.3	-1.3	-2.0	-1.3	-1.2	-1.3	-0.3	-1.4	-1.3	-1.3	-2.0	-1.2	-1.3	-1.4	-1.5	-0.9	-1.3	-1.4	-0.9	-1.4	-1.5	-1.5
Medication: Omeprazole	1.4	1.7	4.0	1.4	1.8	1.2	0.2	-0.4	1.2	1.2	1.2	1.5	1.3	1.2	1.2	1.5	1.2	0.8	1.3	1.4	1.2	1.2	1.9	0.3	2.0	1.3	1.7
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.9	4.8	-1.6	-2.2	-1.7	-0.3	-1.9	-1.7	-1.7	-1.7	-1.4	-1.8	-1.7	-1.6	-2.1	-1.7	-1.9	-1.7	-1.6	-1.4	-1.7	-1.2	-2.0	-1.4	-1.9	-1.8
Medication: Bendroflumethiazide	1.4	2.1	3.4	-1.5	-1.1	-1.5	-0.7	0.2	-1.5	-1.5	-1.5	-1.1	-1.5	-1.5	-1.6	-1.6	-1.5	-1.7	-1.4	-1.6	-1.1	-1.5	-1.8	-1.1	-1.7	-1.5	-1.7
Type 2 Diabetes (T2D) (2018)	1.3	2.5	6.5	1.8	1.3	1.7	2.5	1.9	1.7	1.8	1.7	0.9	1.5	1.6	1.8	1.4	1.8	1.1	1.4	1.5	1.6	1.7	1.5	0.8	1.7	1.3	1.3
Medication: Levothyroxine sodium	1.3	2.1	3.6	-1.5	-1.2	-1.4	-0.9	-1.5	-1.4	-1.4	-1.4	-1.5	-1.7	-1.4	-1.5	-1.4	-1.4	-1.5	-1.6	-1.7	-1.6	-1.5	-1.3	-1.2	-1.5	-1.4	-1.9
Age at first live birth	1.3	2.2	4.7	1.5	0.8	1.4	1.6	0.8	1.4	1.4	1.4	1.0	1.3	1.4	1.6	1.7	1.4	1.3	1.4	1.5	2.1	1.4	2.2	1.8	1.7	1.5	1.8
Fasting Glucose	1.2	1.4	3.4	1.2	1.4	1.1	0.8	0.9	1.1	1.1	1.1	0.8	1.2	1.1	1.2	1.3	1.1	1.9	1.2	1.3	1.0	1.2	1.3	0.8	1.2	1.3	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	4.6	-1.3	-1.0	-1.2	-1.6	-0.9	-1.2	-1.2	-1.2	-0.6	-1.3	-1.2	-1.4	-1.8	-1.2	-1.3	-1.2	-1.4	-2.1	-1.2	-1.9	-0.6	-1.7	-1.1	-1.8
Knee pain experienced in last month	1.2	1.9	2.9	1.5	1.2	1.4	1.7	-1.1	1.5	1.5	1.4	1.4	1.3	1.4	1.6	1.1	1.5	1.6	1.3	1.3	1.2	1.4	1.2	1.3	1.1	1.5	1.2
Ever smoked	1.2	2.1	5.6	-1.4	-0.7	-1.3	-1.3	-2.4	-1.3	-1.3	-1.3	-1.3	-1.3	-1.3	-1.4	-1.8	-1.3	-1.1	-1.4	-1.5	-1.2	-1.3	-2.2	-1.3	-1.7	-1.0	-1.6
Supplements: Calcium	1.2	1.3	4.0	1.1	2.0	1.3	0.6	0.8	1.3	1.2	1.2	1.1	1.3	1.3	1.0	1.5	1.2	1.3	1.2	1.2	0.6	1.3	0.2	1.1	0.6	1.2	0.6
Age when periods started (menarche)	1.1	2.6	5.9	1.7	2.4	1.9	1.3	0.4	1.9	2.0	1.8	0.6	1.7	1.8	1.6	1.4	2.0	1.7	1.5	1.5	0.9	1.9	0.6	1.7	0.9	2.3	1.4
Had other major operations	1.1	1.3	3.9	1.3	1.3	1.2	0.2	0.9	1.2	1.3	1.2	0.7	1.1	1.2	1.2	1.3	1.3	1.2	1.0	1.0	0.7	1.2	1.0	2.0	0.9	1.4	1.0
Illnesses of father: Heart disease	1.1	1.5	4.7	1.3	0.9	1.2	1.2	2.2	1.2	1.2	1.2	0.2	1.3	1.2	1.2	1.0	1.2	1.2	1.2	1.2	1.2	1.2	1.0	1.1	1.1	1.3	1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.2	1.2	1.2	1.2	0.3	-1.4	1.2	1.2	1.2	1.0	1.1	1.2	1.2	1.2	1.2	1.5	1.2	1.0	0.5	1.2	0.6	1.1	0.7	1.0	0.8
Medication: Blood pressure	1.1	2.1	5.0	-1.5	-1.0	-1.5	-2.2	-0.9	-1.5	-1.5	-1.5	-1.6	-1.5	-1.5	-1.6	-1.4	-1.5	-1.6	-1.5	-1.5	-1.7	-1.5	-1.3	-0.2	-1.4	-0.8	-1.3
Heart attack/myocardial infarction (self-reported)	1.1	1.5	3.8	-1.1	-1.0	-1.1	-1.9	-1.1	-1.1	-1.0	-1.1	-0.8	-1.1	-1.1	-1.1	-1.2	-1.0	-1.2	-1.3	-1.1	-1.6	-1.1	-1.1	-1.8	-1.2	-1.1	-1.3
Schizophrenia vs Biploar Disorder	1.0	1.3	2.6	-1.2	-1.0	-1.3	-1.6	1.1	-1.2	-1.3	-1.2	-0.5	-1.1	-1.2	-1.3	-1.2	-1.3	-1.6	-0.9	-0.9	-0.7	-1.2	-0.5	-1.4	-0.6	-1.1	-1.0
Ovarian Cancer	1.0	1.4	3.1	1.2	1.7	1.3	0.9	0.9	1.3	1.3	1.3	0.6	1.1	1.3	1.1	1.2	1.3	1.0	1.2	1.1	0.5	1.2	0.7	1.8	0.8	1.5	0.7
Allergy or Eczema	1.0	2.7	6.1	1.6	2.5	1.4	0.8	1.8	1.5	1.4	1.5	0.3	1.6	1.5	1.2	1.4	1.4	2.1	1.7	1.7	0.8	1.5	1.7	2.3	1.8	2.2	1.6
Chronic bronchitis/emphysema (father)	1.0	1.1	3.4	1.1	1.7	1.1	-0.5	0.3	1.1	1.1	1.0	1.0	0.9	1.0	0.8	0.9	1.1	1.2	0.9	0.9	0.1	1.0	1.2	1.9	1.1	1.3	0.9
Qualifications: College or University degree	1.0	3.1	5.1	1.6	0.8	1.6	1.3	2.1	1.6	1.5	1.7	0.6	1.9	1.7	1.8	2.2	1.5	1.5	2.1	2.0	2.3	1.7	1.8	2.0	1.7	1.7	2.1
Chest pain or discomfort	1.0	1.4	5.0	-1.0	-0.4	-1.0	-1.4	-2.2	-1.0	-1.0	-0.9	-2.1	-0.8	-0.9	-1.1	-1.1	-1.0	-0.9	-0.7	-0.8	-2.0	-0.9	-1.0	-0.6	-0.9	-1.1	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.6	-1.1	-1.2	-1.2	-0.7	-1.3	-1.2	-1.3	-1.1	-0.9	-0.9	-1.1	-1.1	-1.4	-1.3	-0.9	-0.8	-0.8	-0.2	-1.1	-0.6	-1.6	-0.5	-1.4	-0.7
Back pain experienced in last month	1.0	1.4	3.5	1.3	0.9	1.2	1.0	-0.4	1.2	1.2	1.2	1.3	1.2	1.2	1.3	0.4	1.2	1.4	1.1	1.4	0.9	1.2	1.9	0.4	1.7	0.9	1.2
Cholesterol lowering medication	1.0	1.5	4.4	-1.1	-0.3	-1.1	-2.1	-1.7	-1.1	-1.1	-1.1	-1.2	-1.0	-1.1	-1.3	-1.3	-1.1	-0.8	-1.0	-1.1	-2.0	-1.0	-1.4	-0.3	-1.4	-0.5	-1.2
Medication: Omeprazole (e.g. Zanprol)	1.0	1.3	3.1	1.1	1.8	1.0	-0.2	-1.4	1.0	1.0	1.0	1.4	1.0	1.0	0.9	1.4	1.0	0.6	1.0	1.0	0.9	1.0	1.5	0.2	1.6	1.1	1.3
Alzheimer’s Disease (in mother)	0.9	1.1	3.1	1.1	0.7	1.2	0.8	1.8	1.2	1.2	1.1	1.0	1.1	1.1	1.1	0.8	1.2	1.1	1.0	1.0	0.9	1.1	0.7	0.6	0.8	0.6	0.6
Cardiovascular Disease	0.9	3.0	6.2	-1.6	-1.5	-1.6	-1.0	-1.9	-1.6	-1.6	-1.7	-2.5	-1.7	-1.7	-1.7	-2.3	-1.6	-2.1	-1.8	-1.7	-2.1	-1.6	-1.5	-1.3	-1.6	-1.7	-1.9
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	3.3	1.2	1.2	1.2	0.7	1.1	1.2	1.1	1.2	-0.1	1.3	1.2	1.1	0.6	1.1	0.9	1.2	1.3	0.3	1.2	0.9	1.8	0.9	1.1	0.9
Severe depression (siblings)	0.9	1.1	5.0	0.9	0.5	0.9	0.7	2.2	1.0	0.9	1.0	0.3	1.0	1.0	1.0	1.1	0.9	1.0	1.2	1.1	1.4	1.0	0.9	0.9	1.0	0.6	0.7
Heart attack	0.9	1.2	3.5	-1.0	-0.9	-0.9	-1.9	-1.2	-0.9	-0.9	-1.0	-0.4	-1.0	-1.0	-1.0	-1.1	-0.9	-1.1	-1.1	-1.0	-1.3	-0.9	-1.0	-1.7	-1.1	-0.9	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	3.3	0.8	0.8	0.6	0.7	1.8	0.7	0.6	0.8	1.3	0.9	0.8	0.8	0.6	0.6	1.1	1.1	1.0	1.0	0.8	0.9	1.8	1.0	1.5	1.3
Had major operations	0.9	1.0	4.2	-1.1	0.0	-0.8	-2.0	-1.1	-0.8	-0.8	-0.9	-0.4	-1.0	-0.9	-1.0	-0.8	-0.8	-0.7	-0.9	-1.1	-1.0	-0.8	-1.8	-0.4	-1.7	-0.2	-0.9
Mood swings	0.9	1.7	4.8	-1.2	-1.2	-1.1	-0.5	-2.2	-1.1	-1.1	-1.1	-0.2	-1.2	-1.1	-1.1	-1.5	-1.1	-1.3	-1.2	-1.2	-1.3	-1.1	-1.5	-2.2	-1.2	-1.4	-1.5
Qualifications: nursing, teaching	0.9	1.4	3.1	-1.4	-1.8	-1.4	-0.6	-1.3	-1.4	-1.5	-1.4	-0.5	-1.2	-1.4	-1.2	-1.3	-1.5	-1.2	-1.1	-1.2	-0.4	-1.3	-1.1	-0.2	-1.3	-0.9	-0.7
Osteoporosis (self-reported)	0.9	1.1	2.8	-1.0	-1.2	-1.2	-1.1	-1.1	-1.2	-1.2	-1.1	-1.7	-1.0	-1.1	-1.2	-0.6	-1.2	-0.8	-0.9	-0.8	-1.1	-1.1	-0.1	-0.9	-0.4	-1.3	-1.0
Fractured/broken bones in last 5 years	0.9	1.1	2.0	1.2	1.2	1.1	0.8	0.3	1.1	1.0	1.2	0.3	1.2	1.2	1.1	0.8	1.0	0.9	1.4	1.2	1.1	1.1	1.0	1.3	1.1	0.9	1.0
Sensitivity / hurt feelings	0.8	1.4	3.3	-1.1	-1.2	-1.2	-1.6	-0.5	-1.2	-1.2	-1.2	-1.8	-1.2	-1.2	-1.2	-1.4	-1.2	-1.4	-1.2	-1.1	-1.3	-1.2	-0.6	-0.8	-0.8	-1.0	-1.2
Supplements: Zinc	0.8	0.9	2.3	-1.0	-0.6	-1.0	-1.1	-0.4	-1.0	-1.1	-1.0	-1.5	-0.7	-0.9	-1.1	-0.9	-1.1	-0.6	-0.6	-0.7	-1.2	-0.9	-0.8	-0.6	-0.9	-0.5	-0.9
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	3.1	-0.9	-0.8	-0.8	-1.4	-0.8	-0.9	-0.8	-0.9	-0.5	-0.9	-0.9	-0.9	-1.6	-0.8	-0.5	-1.0	-0.9	-0.6	-0.9	-0.7	-1.8	-0.7	-1.0	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.8	-0.9	-0.4	-1.1	-0.7	-1.9	-1.1	-1.1	-1.0	-1.5	-1.0	-1.0	-1.2	-0.9	-1.1	-1.1	-0.9	-0.9	-1.8	-1.1	-0.7	-1.1	-0.7	-0.8	-1.1
Allergy	0.8	1.9	5.8	-1.5	-2.0	-1.2	-0.7	-1.1	-1.2	-1.2	-1.3	0.2	-1.3	-1.3	-1.1	-1.2	-1.2	-1.6	-1.4	-1.3	-1.0	-1.3	-1.4	-2.4	-1.5	-1.6	-1.3
Prospective memory result	0.8	1.0	2.7	-1.0	-1.2	-1.1	-0.8	-0.4	-1.1	-1.1	-1.2	-0.6	-1.1	-1.2	-1.1	-1.2	-1.1	-0.7	-1.3	-0.9	-0.1	-1.1	-0.3	-1.6	-0.3	-1.2	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	5.4	-0.7	-0.4	-0.7	-0.3	-1.9	-0.8	-0.7	-0.7	-2.3	-0.8	-0.7	-0.9	-1.0	-0.7	-0.8	-0.7	-0.8	-1.3	-0.7	-0.9	-0.1	-1.0	-0.4	-1.1
Leg pain on walking	0.8	1.0	2.6	1.0	1.0	1.1	0.8	1.3	1.1	1.1	1.0	0.3	0.9	1.0	1.1	1.6	1.1	0.9	0.9	0.9	0.9	1.0	1.2	-0.2	1.2	0.6	0.9
Supplements: Vitamin C	0.8	1.0	4.0	0.8	2.0	0.9	0.8	0.9	0.9	0.9	0.9	-0.2	1.0	0.9	0.7	1.0	0.9	1.1	1.1	1.0	0.7	1.0	0.7	1.4	0.9	1.3	0.8
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.6	-0.9	-1.2	-1.0	-0.3	-1.2	-1.0	-1.0	-1.0	-1.0	-1.0	-1.0	-0.9	-1.0	-1.0	-1.3	-0.9	-1.0	-0.2	-1.0	-1.2	-0.8	-1.1	-1.2	-1.0
Loneliness, isolation	0.8	1.2	6.1	-0.9	-0.1	-1.0	-1.3	-0.4	-1.0	-1.0	-1.0	-1.4	-0.9	-1.0	-1.2	-0.7	-1.0	-1.2	-1.0	-0.9	-2.5	-1.0	-0.7	-0.6	-0.8	-0.6	-1.3
Unable to work because of sickness or disability	0.8	1.0	2.2	-0.9	-1.1	-0.9	-0.7	-1.5	-0.9	-0.9	-0.9	-0.2	-1.0	-0.9	-0.9	-1.0	-0.9	-1.1	-1.1	-1.0	-1.1	-0.9	-1.1	-1.2	-1.0	-1.1	-1.1
Vascular/heart problems diagnosed by doctor	0.8	2.1	8.7	1.3	0.2	1.1	1.8	2.2	1.1	1.1	1.2	3.0	1.1	1.2	1.4	1.5	1.1	1.2	1.2	1.2	2.2	1.1	1.7	0.0	1.6	0.6	1.5
Neuroticism (Nagel 2018)	0.7	1.6	4.4	-1.1	-0.2	-1.2	-2.1	-1.5	-1.2	-1.2	-1.2	-1.0	-1.1	-1.2	-1.6	-1.7	-1.2	-1.1	-1.1	-1.0	-2.0	-1.2	-0.8	-0.7	-0.7	-0.7	-1.5
Chronotype (morning person)	0.7	1.5	2.4	1.2	1.6	1.3	0.9	0.5	1.3	1.3	1.3	1.3	1.2	1.3	1.3	1.5	1.3	1.4	1.2	1.2	1.2	1.2	1.4	0.5	1.4	1.1	1.3
Taking other prescription medications	0.7	1.1	3.1	1.3	1.8	1.2	0.2	-0.3	1.2	1.2	1.1	-0.2	1.1	1.1	0.9	1.1	1.2	0.8	1.0	1.0	-0.3	1.1	0.8	1.1	1.0	1.2	0.9
Qualifications: None of the above	0.7	1.4	7.2	-0.9	-0.9	-0.9	-1.6	-2.7	-0.9	-0.9	-1.1	-0.7	-0.9	-1.1	-1.1	-0.9	-0.9	-0.7	-1.3	-1.0	-1.6	-0.9	-1.0	-1.3	-1.0	-1.2	-1.4
Pain all over the body in last month	0.7	0.7	5.6	-0.7	-0.6	-0.7	-0.7	-2.4	-0.7	-0.7	-0.7	-1.3	-0.7	-0.7	-0.7	-0.4	-0.7	-1.0	-0.7	-0.8	-0.6	-0.7	-0.7	-0.0	-0.7	-0.6	-0.9
Number of live births	0.7	0.9	2.3	1.0	0.9	0.9	0.3	-1.5	0.9	0.9	0.9	1.5	1.1	0.9	0.9	0.6	0.9	0.7	1.0	1.0	0.6	0.9	0.9	0.8	1.1	1.1	1.0
Long-standing illness, disability or infirmity	0.7	1.1	2.8	1.3	1.1	1.1	1.2	0.9	1.1	1.1	1.1	0.0	1.1	1.1	1.0	1.4	1.1	0.7	1.0	1.1	-0.1	1.1	0.9	1.7	1.0	1.0	0.5
Ever had bowel cancer screening	0.7	0.9	1.6	0.8	0.9	1.0	1.2	1.2	1.0	1.0	0.9	1.3	0.8	0.9	1.0	1.0	1.0	1.0	0.6	0.7	0.9	0.9	0.2	1.0	0.5	1.1	0.9
Financial situation satisfaction	0.7	0.8	2.1	-0.8	-1.0	-0.9	-0.5	-0.2	-0.9	-0.9	-1.0	-1.0	-0.8	-1.0	-0.9	-1.5	-0.9	-0.9	-1.0	-0.8	-1.4	-0.9	-0.2	-0.8	-0.4	-0.9	-1.1
Worry (Nagel 2018)	0.6	1.2	4.3	-1.1	-0.2	-1.2	-1.3	-0.9	-1.2	-1.2	-1.1	-0.7	-1.0	-1.1	-1.5	-2.1	-1.2	-0.7	-1.0	-0.9	-1.6	-1.1	-0.4	-0.6	-0.5	-0.7	-1.3
Alzheimer’s Disease (in father)	0.6	0.6	2.1	-0.6	-1.1	-0.7	0.6	0.4	-0.7	-0.6	-0.7	-0.7	-0.8	-0.7	-0.5	-1.1	-0.6	-1.5	-0.9	-0.7	-0.2	-0.8	0.1	-1.4	0.0	-1.0	-0.4
Reaction Time	0.6	1.2	4.6	-1.1	-0.2	-1.1	-2.1	-0.7	-1.1	-1.1	-1.1	-0.3	-1.1	-1.1	-1.4	-0.9	-1.1	-1.2	-1.1	-1.0	-1.4	-1.1	-0.8	-0.7	-0.8	-0.5	-1.1
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.3	-0.7	0.0	-0.6	-0.1	-1.2	-0.6	-0.5	-0.5	0.7	-0.9	-0.5	-0.8	-1.5	-0.5	-0.8	-0.6	-1.0	-0.9	-0.5	-1.4	-1.1	-1.2	-0.8	-1.2
Average weekly spirits intake	0.6	0.8	3.5	0.6	1.3	0.8	0.0	1.6	0.8	0.8	0.8	-0.0	0.8	0.8	0.6	1.9	0.8	1.0	0.8	0.8	0.6	0.8	0.3	1.2	0.5	0.9	0.5
High blood pressure	0.6	1.8	7.7	-1.3	-0.3	-1.1	-1.5	-1.7	-1.1	-1.1	-1.2	-2.8	-1.1	-1.1	-1.3	-1.3	-1.1	-1.2	-1.2	-1.2	-2.0	-1.1	-1.7	-0.2	-1.5	-0.7	-1.4
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.9	1.1	1.5	1.0	0.9	1.1	1.0	0.9	1.1	0.0	1.1	1.1	0.9	0.9	0.9	1.5	1.3	1.2	1.0	1.1	1.2	1.7	1.3	1.4	1.4
High blood pressure (mother)	0.6	0.8	3.8	0.6	1.8	0.7	-0.3	0.6	0.7	0.7	0.7	-0.6	0.8	0.7	0.4	0.3	0.7	0.7	0.8	0.7	-1.0	0.7	0.4	2.0	0.3	1.8	0.7
Impedance of leg (left)	0.6	3.1	4.6	-1.9	-1.8	-1.9	-0.8	-0.8	-2.0	-1.9	-2.0	-0.8	-1.9	-2.0	-2.0	-2.0	-1.9	-1.8	-2.0	-1.9	-1.2	-1.9	-1.5	-2.1	-1.4	-1.9	-1.6
Hair/balding pattern: Pattern 3	0.6	0.9	2.5	-1.0	-0.6	-0.9	-0.0	0.6	-0.9	-0.9	-0.9	-0.9	-0.9	-0.9	-1.0	-1.1	-0.9	-0.6	-0.9	-1.1	-1.1	-0.9	-1.6	-0.2	-1.4	-0.9	-1.1
Tense / ‘highly strung’	0.6	1.1	3.1	-1.1	-0.8	-1.1	-0.8	-1.4	-1.1	-1.2	-1.1	0.1	-1.0	-1.1	-1.2	-1.8	-1.2	-0.8	-0.9	-0.8	-1.1	-1.1	-0.3	-1.3	-0.5	-0.7	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.7	0.9	1.0	0.8	-0.4	-0.1	0.9	0.8	0.9	1.3	0.8	0.9	0.8	0.3	0.8	0.8	0.9	0.9	0.2	0.9	1.1	0.2	1.3	0.9	1.1
Number of self-reported non-cancer illnesses	0.6	1.0	2.4	1.1	1.6	1.1	-0.5	-0.8	1.1	1.1	1.1	0.6	1.2	1.1	1.0	0.0	1.1	1.2	1.0	1.1	0.0	1.2	1.0	1.0	1.1	1.1	0.9
Miserableness	0.6	1.0	4.2	-0.8	-0.8	-0.8	0.2	-0.6	-0.8	-0.8	-0.8	-1.5	-0.9	-0.8	-1.0	-0.9	-0.8	-1.0	-0.9	-0.9	-2.0	-0.8	-1.3	-0.3	-1.1	-0.8	-1.6
Medication: Lisinopril	0.6	0.8	4.7	-0.8	-0.3	-0.7	-1.2	-2.2	-0.7	-0.7	-0.7	-0.3	-0.7	-0.7	-0.7	-1.2	-0.7	-0.5	-0.8	-0.8	-1.0	-0.7	-1.2	-0.8	-1.0	-0.7	-0.4
Diastolic blood pressure, automated reading	0.6	1.8	3.2	-1.4	-0.6	-1.2	-1.6	-0.9	-1.3	-1.2	-1.3	-0.7	-1.5	-1.3	-1.5	-1.8	-1.2	-1.0	-1.4	-1.5	-1.6	-1.3	-1.4	-1.6	-1.3	-1.3	-1.5
Pack years of smoking	0.6	0.9	1.7	1.1	0.6	1.0	0.3	-0.5	1.0	1.0	1.0	0.6	1.0	1.0	1.1	0.9	1.0	1.1	1.0	1.0	1.3	1.0	1.3	0.6	1.2	0.3	1.2
Ulcerative Colitis (UC)	0.5	0.9	1.9	-1.0	-0.4	-1.0	-0.3	0.6	-1.0	-1.0	-1.0	-0.9	-0.9	-1.0	-1.1	-0.7	-1.0	-1.1	-1.0	-0.9	-1.4	-1.0	-1.2	0.0	-1.2	-0.5	-1.0
Waist Hip Ratio (WHR)	0.5	2.2	4.2	-1.5	-1.5	-1.6	-1.6	-1.7	-1.5	-1.6	-1.5	-1.2	-1.3	-1.5	-1.6	-2.0	-1.6	-1.1	-1.2	-1.2	-1.4	-1.5	-0.9	-1.9	-0.9	-2.0	-1.4
Respiratory disease	0.5	1.0	2.9	1.0	1.6	1.1	-0.6	1.7	1.1	1.1	1.1	0.4	0.9	1.1	0.8	0.9	1.1	1.0	0.9	0.8	0.0	1.0	0.6	1.4	0.8	1.0	0.6
Lung FEV1/FVC ratio	0.5	2.6	4.0	-1.8	-2.0	-1.9	-0.5	-1.2	-1.8	-1.9	-1.8	-1.4	-1.7	-1.8	-1.7	-1.7	-1.9	-1.9	-1.6	-1.6	-1.1	-1.8	-1.7	-0.8	-1.7	-1.2	-1.5
Pack years adult smoking proportion	0.5	0.8	1.5	1.0	0.6	0.9	0.3	-0.7	0.9	0.9	0.9	0.6	0.9	0.9	1.0	0.7	0.9	1.0	0.9	0.9	1.2	0.9	1.2	0.6	1.1	0.3	1.2
Impedance of leg (right)	0.5	2.4	4.1	-1.7	-1.8	-1.7	-0.5	-0.4	-1.8	-1.7	-1.8	-0.8	-1.7	-1.8	-1.8	-1.6	-1.7	-1.7	-1.8	-1.7	-0.9	-1.7	-1.1	-2.0	-1.1	-1.8	-1.4
Nervous feelings	0.5	1.0	3.1	-1.0	-0.5	-0.9	-1.4	-0.6	-1.0	-0.9	-0.9	-0.1	-1.0	-1.0	-1.2	-1.8	-0.9	-0.8	-1.0	-1.0	-1.3	-1.0	-0.6	-1.2	-0.6	-1.1	-1.1
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	5.0	-1.3	-2.2	-1.4	0.1	0.2	-1.3	-1.4	-1.4	0.1	-1.4	-1.4	-1.0	-1.3	-1.4	-1.3	-1.3	-1.2	0.1	-1.3	-1.0	-1.6	-1.0	-1.7	-0.9
Happiness	0.5	0.7	1.6	0.9	0.9	0.8	-0.2	0.0	0.8	0.7	0.8	-0.5	1.1	0.8	0.7	0.1	0.7	0.8	1.0	1.2	-0.4	0.9	1.3	0.7	1.2	0.8	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	4.0	0.8	0.3	0.6	0.4	0.8	0.6	0.5	0.6	-0.5	0.8	0.6	0.7	0.4	0.5	0.6	0.7	0.9	0.6	0.6	2.0	1.0	1.5	0.6	0.8
Hair/balding pattern: Pattern 4	0.5	1.3	2.2	-1.1	-1.3	-1.1	-1.0	-1.2	-1.2	-1.2	-1.1	-0.7	-1.0	-1.1	-1.2	-1.1	-1.2	-1.1	-1.1	-1.1	-0.9	-1.1	-0.9	-1.5	-1.0	-1.5	-1.5
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.1	0.8	1.4	0.8	-0.4	0.4	0.8	0.8	0.8	0.3	1.0	0.8	0.7	0.3	0.8	0.9	0.9	0.9	0.1	0.9	0.8	0.1	0.9	0.2	0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.0	-0.7	-0.9	-0.8	-0.7	0.2	-0.8	-0.8	-0.8	-1.4	-0.8	-0.8	-0.8	-1.1	-0.8	-1.2	-0.7	-0.7	-0.7	-0.8	-0.4	-0.4	-0.5	-0.8	-0.9
Headache pain in last month	0.5	0.8	2.0	-0.9	-1.4	-0.8	0.9	0.3	-0.8	-0.9	-0.8	0.2	-0.7	-0.8	-0.8	-1.1	-0.9	-0.6	-0.7	-0.8	-1.4	-0.8	-0.8	-0.7	-1.0	-1.2	-1.2
Pulse rate, automated reading	0.5	1.7	3.0	1.5	0.8	1.5	1.5	1.3	1.5	1.6	1.4	1.7	1.2	1.4	1.5	1.3	1.6	0.8	1.0	1.2	0.9	1.4	1.1	1.2	1.1	1.5	1.1
Family relationship satisfaction	0.5	0.6	1.9	-0.7	-0.5	-0.7	-1.0	-0.7	-0.7	-0.8	-0.7	-1.4	-0.5	-0.7	-0.8	-1.1	-0.8	-0.8	-0.4	-0.5	-1.2	-0.7	-0.5	-0.6	-0.6	-0.7	-0.7
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.1	0.9	0.5	1.0	1.0	0.4	0.9	1.0	1.0	0.5	0.8	1.0	0.9	0.9	1.0	0.4	1.0	0.8	0.4	0.9	0.7	-0.4	0.7	0.6	0.6
Eye problems/disorders: Cataract	0.5	0.5	1.6	0.6	1.3	0.7	-0.0	-1.1	0.7	0.7	0.8	-0.1	0.8	0.8	0.7	1.0	0.7	1.0	0.9	0.7	0.4	0.7	-0.1	0.3	0.2	0.9	0.7
Commuting to job workplace: Public transport	0.5	0.6	1.6	0.8	0.8	1.0	0.2	0.9	0.9	1.0	0.9	-0.6	0.9	0.9	0.9	1.3	1.0	0.0	0.8	0.7	0.5	0.9	0.2	0.6	0.5	0.9	0.8
Height	0.4	7.0	9.1	-2.8	-2.7	-3.0	-2.6	-0.1	-3.0	-2.9	-3.0	-2.3	-3.0	-3.0	-2.8	-2.5	-2.9	-2.8	-3.0	-3.0	-1.6	-3.0	-2.5	-2.3	-2.6	-2.4	-2.2
Angina	0.4	0.5	3.0	0.4	1.0	0.4	-1.4	-1.7	0.4	0.4	0.4	-0.9	0.5	0.5	0.2	-0.1	0.4	0.5	0.6	0.5	-0.6	0.5	0.1	1.5	-0.0	0.9	-0.0
Relative age voice broke	0.4	0.7	2.0	-0.9	-0.5	-0.9	0.5	-0.7	-0.9	-0.8	-0.9	-0.9	-1.0	-0.9	-0.9	-1.2	-0.8	-0.7	-1.0	-0.9	-1.4	-0.9	-0.5	-0.3	-0.6	-0.2	-0.6
Medication: Simvastatin	0.4	0.5	2.0	-0.5	0.1	-0.4	-1.4	-1.4	-0.4	-0.4	-0.5	-0.7	-0.5	-0.5	-0.6	-0.9	-0.4	-0.9	-0.7	-0.6	-1.3	-0.4	-0.8	0.0	-0.8	-0.1	-0.9
Arm fat mass (right)	0.4	1.5	3.6	-1.1	-0.8	-1.1	-1.9	-1.5	-1.1	-1.1	-1.2	-0.9	-1.1	-1.1	-1.2	-1.0	-1.1	-1.1	-1.2	-1.2	-1.7	-1.1	-1.7	-0.2	-1.7	-0.8	-1.5
Exposure to tobacco smoke outside home	0.4	0.6	3.2	-0.7	-0.1	-0.5	-1.8	1.0	-0.5	-0.6	-0.5	-0.4	-0.4	-0.5	-0.7	-0.6	-0.6	0.1	-0.4	-0.5	-1.4	-0.5	-0.9	-1.0	-0.8	-0.5	-0.6
Number of full brothers	0.4	0.5	2.0	-0.4	-1.0	-0.4	0.1	-1.4	-0.4	-0.4	-0.5	0.2	-0.4	-0.5	-0.2	-1.3	-0.4	-0.3	-0.6	-0.4	0.3	-0.4	-0.4	-1.4	-0.3	-1.2	-0.6
Number of children fathered	0.4	0.5	1.5	-0.6	-0.8	-0.8	0.1	-0.1	-0.7	-0.7	-0.8	-1.0	-0.7	-0.8	-0.7	-0.1	-0.7	-1.2	-0.8	-0.7	-0.4	-0.7	-0.6	0.3	-0.7	-0.1	-0.6
Shortness of breath walking on level ground	0.4	0.5	1.7	-0.5	-0.9	-0.6	-1.3	-0.4	-0.6	-0.7	-0.7	-0.5	-0.5	-0.6	-0.6	-0.8	-0.7	-0.8	-0.6	-0.6	-0.9	-0.6	-0.6	0.0	-0.7	-0.6	-0.8
Number of full sisters	0.4	0.5	1.4	0.7	1.1	0.8	0.9	-0.8	0.7	0.9	0.8	1.2	0.4	0.7	0.6	0.2	0.9	0.6	0.5	0.3	0.4	0.7	0.3	0.2	0.3	0.9	0.4
Hypertension (Self-reported)	0.4	1.1	7.0	-0.9	0.1	-0.8	-0.9	-1.4	-0.8	-0.8	-0.8	-2.6	-0.7	-0.8	-1.0	-0.9	-0.8	-0.9	-0.8	-0.8	-1.6	-0.7	-1.3	0.3	-1.2	-0.2	-0.9
Hearing aid user	0.4	0.5	2.6	0.1	1.5	0.0	-1.3	-0.1	0.0	0.2	-0.1	-0.1	-0.4	-0.1	-0.5	0.4	0.2	-0.6	-0.5	-0.5	-1.6	-0.1	-0.8	1.0	-0.8	0.8	-0.4
Mother’s age at death	0.4	0.5	1.2	-0.7	-0.1	-0.7	-1.1	1.1	-0.7	-0.8	-0.6	-0.4	-0.5	-0.5	-0.7	-0.5	-0.8	-0.5	-0.1	-0.5	-0.6	-0.6	-1.0	1.1	-1.0	-0.0	-0.3
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.3	0.6	1.1	0.7	-0.8	0.4	0.7	0.7	0.7	0.0	0.8	0.7	0.6	0.6	0.7	0.6	0.8	0.7	-0.3	0.7	0.2	0.7	0.3	0.8	0.5
Leg fat mass (left)	0.4	1.4	3.0	-1.1	-0.7	-1.0	-1.7	-1.3	-1.0	-1.0	-1.1	-0.8	-1.1	-1.1	-1.2	-1.0	-1.0	-1.0	-1.2	-1.2	-1.7	-1.0	-1.7	-0.5	-1.6	-0.8	-1.4
Bipolar Disorder (2018)	0.3	0.5	2.2	0.6	0.6	0.6	1.4	1.5	0.6	0.6	0.5	-0.1	0.4	0.5	0.5	0.9	0.6	0.7	0.3	0.4	0.1	0.5	0.1	1.0	0.2	0.7	0.2
Alzheimer’s Disease (including proxy)	0.3	0.5	4.4	0.6	-0.0	0.6	1.0	2.1	0.6	0.7	0.5	0.8	0.4	0.5	0.7	0.1	0.7	0.2	0.2	0.5	0.7	0.6	0.5	-0.1	0.6	-0.1	0.2
Coronary Artery Disease (CAD)	0.3	0.3	1.1	-0.6	-0.5	-0.6	-0.1	-0.6	-0.6	-0.7	-0.7	-0.6	-0.4	-0.7	-0.5	-0.2	-0.7	-0.7	-0.6	-0.5	-0.3	-0.4	-0.6	-1.1	-0.4	-0.7	-0.5
Schizophrenia (2014)	0.3	0.8	2.6	-0.9	-0.4	-0.9	-1.0	0.8	-0.9	-0.9	-0.8	-0.4	-0.8	-0.8	-1.1	-0.5	-0.9	-1.0	-0.7	-0.8	-1.6	-0.9	-1.1	-0.5	-1.0	-0.6	-0.7
Triglycerides	0.3	0.5	2.9	-0.7	-0.3	-0.8	-1.7	-0.0	-0.7	-0.8	-0.7	-0.4	-0.7	-0.7	-0.9	-0.1	-0.8	-0.4	-0.6	-0.6	-0.9	-0.8	-0.1	-0.6	-0.3	-0.9	-1.1
Hypothyroidism (self reported)	0.3	0.8	2.7	-0.7	-0.0	-0.7	-0.2	-1.2	-0.7	-0.6	-0.7	-0.9	-1.1	-0.8	-1.0	-0.4	-0.6	-1.3	-1.0	-1.1	-1.6	-0.8	-0.8	-0.3	-1.0	-0.5	-1.3
Medication: Co-codamol	0.3	0.3	3.2	0.5	0.6	0.6	-0.3	0.3	0.6	0.6	0.5	1.8	0.3	0.5	0.4	0.4	0.6	0.2	0.2	0.2	-0.4	0.5	0.1	-0.0	0.3	0.6	0.1
Diabetes (father)	0.3	0.4	1.7	0.5	0.3	0.6	0.8	-0.0	0.6	0.7	0.6	1.2	0.5	0.6	0.7	-0.1	0.7	0.7	0.5	0.4	1.3	0.6	0.1	-0.3	0.4	-0.1	0.4
Average weekly fortified wine intake	0.3	0.4	1.9	0.4	-0.1	0.5	1.0	0.5	0.5	0.5	0.5	1.0	0.5	0.5	0.6	0.7	0.5	0.5	0.6	0.5	1.4	0.5	0.7	-0.6	0.8	-0.1	0.7
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.2	-0.2	-0.8	-0.2	1.5	1.0	-0.2	-0.1	-0.2	0.3	-0.4	-0.2	0.0	-0.4	-0.1	-0.2	-0.2	-0.3	0.7	-0.2	-0.2	-0.6	-0.2	-0.8	-0.5
Medication: Atenolol	0.3	0.4	1.8	-0.5	0.6	-0.5	-1.3	-0.3	-0.5	-0.6	-0.5	-1.2	-0.3	-0.5	-0.8	-0.5	-0.6	-0.3	-0.3	-0.3	-1.1	-0.5	-0.0	0.3	-0.2	0.3	-0.3
Waist circumference	0.3	1.0	2.4	-0.8	-0.7	-0.8	-1.4	-1.6	-0.8	-0.9	-0.9	-1.1	-0.8	-0.9	-0.9	-0.9	-0.9	-0.8	-0.9	-0.9	-1.5	-0.8	-1.2	-0.3	-1.2	-1.0	-1.4
Past tobacco smoking	0.3	0.5	4.7	0.4	-0.0	0.3	0.6	2.2	0.3	0.3	0.4	0.2	0.4	0.4	0.5	1.1	0.3	0.1	0.5	0.5	0.4	0.4	1.2	0.5	0.8	0.1	0.9
Forced vital capacity (FVC)	0.3	1.3	4.2	-1.1	-2.1	-1.2	-0.0	-0.2	-1.2	-1.2	-1.2	0.4	-1.2	-1.2	-0.8	-1.0	-1.2	-1.2	-1.2	-1.1	0.5	-1.2	-0.7	-2.0	-0.7	-1.8	-0.6
Impedance of arm (right)	0.3	1.3	2.0	-1.4	-1.1	-1.3	-0.6	-0.4	-1.4	-1.4	-1.4	-0.8	-1.2	-1.4	-1.4	-0.9	-1.4	-1.3	-1.4	-1.2	-0.2	-1.3	-1.0	-1.1	-1.0	-1.0	-0.7
Trunk fat-free mass	0.3	1.6	2.5	-1.3	-1.4	-1.2	-1.5	-1.1	-1.2	-1.2	-1.2	-0.9	-1.2	-1.2	-1.1	-1.4	-1.2	-1.1	-1.0	-1.3	-1.2	-1.2	-1.6	-1.2	-1.6	-1.4	-1.5
Worrier / anxious feelings	0.3	0.6	1.9	-0.7	-0.3	-0.8	-0.5	-0.5	-0.8	-0.9	-0.7	-1.4	-0.7	-0.7	-1.0	-1.1	-0.9	-0.7	-0.4	-0.5	-1.1	-0.8	-0.1	0.3	-0.1	-0.1	-0.8
Falls in the last year	0.3	0.4	1.5	0.6	0.7	0.7	1.2	0.2	0.7	0.6	0.7	-0.2	0.8	0.7	0.7	0.3	0.6	0.8	0.7	0.7	1.0	0.7	0.3	0.3	0.6	0.3	0.6
Trunk predicted mass	0.3	1.6	2.6	-1.3	-1.4	-1.2	-1.5	-1.1	-1.2	-1.2	-1.2	-0.9	-1.2	-1.2	-1.1	-1.4	-1.2	-1.1	-1.1	-1.3	-1.2	-1.2	-1.6	-1.2	-1.6	-1.5	-1.5
Standing height	0.3	2.6	3.8	-1.9	-1.8	-1.7	-1.1	0.4	-1.7	-1.7	-1.7	-0.9	-1.7	-1.7	-1.6	-1.8	-1.7	-1.6	-1.6	-1.7	-0.7	-1.7	-1.9	-1.7	-1.8	-1.7	-1.4
Breastfed as a baby	0.3	0.4	1.2	0.6	0.8	0.5	0.3	-1.0	0.5	0.5	0.5	0.2	0.4	0.5	0.5	0.8	0.5	0.4	0.4	0.5	0.8	0.5	0.3	1.1	0.5	1.1	1.0
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	2.1	-0.7	0.0	-0.6	-0.4	-0.7	-0.7	-0.5	-0.7	-1.0	-1.0	-0.7	-0.8	-0.5	-0.5	-1.1	-0.9	-1.0	-1.4	-0.7	-1.1	-0.3	-1.1	-0.5	-1.2
Leg fat percentage (right)	0.3	1.0	2.8	-0.8	-0.6	-0.9	-1.3	-1.4	-0.9	-0.9	-1.0	-0.7	-0.9	-1.0	-1.0	-1.0	-0.9	-0.8	-1.1	-1.0	-1.7	-0.9	-1.0	-0.2	-1.1	-0.6	-1.3
Wheeze or whistling in the chest in last year	0.3	0.5	1.1	0.7	0.7	0.7	0.5	0.7	0.7	0.6	0.7	-0.2	0.8	0.7	0.6	0.5	0.6	0.8	0.9	0.8	0.1	0.7	0.5	1.1	0.7	0.8	0.7
Emphysema/chronic bronchitis	0.3	0.3	2.7	0.2	0.3	-0.1	0.4	-1.2	-0.1	-0.2	0.0	-0.9	0.4	0.1	-0.0	0.6	-0.2	-0.0	0.5	0.4	0.5	0.0	0.4	1.6	0.5	0.3	0.4
Angina (self-reported)	0.3	0.4	2.6	0.3	0.9	0.3	-1.3	-1.2	0.4	0.3	0.4	-0.8	0.4	0.4	0.2	-0.1	0.3	0.4	0.5	0.4	-0.7	0.4	0.1	1.6	-0.1	0.9	-0.1
Migraine (self-reported)	0.3	0.4	0.8	0.6	0.4	0.6	0.5	0.6	0.7	0.6	0.6	0.7	0.7	0.6	0.7	0.5	0.6	0.7	0.6	0.8	0.3	0.6	0.9	-0.1	0.9	0.5	0.9
Whole body fat mass	0.3	1.2	3.1	-1.0	-0.6	-1.0	-1.8	-1.3	-0.9	-0.9	-1.0	-0.8	-1.0	-1.0	-1.1	-0.9	-0.9	-1.0	-1.1	-1.0	-1.6	-1.0	-1.4	-0.1	-1.5	-0.5	-1.2
Leg fat mass (right)	0.3	1.2	2.8	-1.0	-0.6	-1.0	-1.6	-1.3	-0.9	-0.9	-1.0	-0.7	-1.0	-1.0	-1.1	-0.9	-0.9	-1.0	-1.1	-1.1	-1.7	-1.0	-1.5	-0.4	-1.5	-0.7	-1.3
Overall health rating	0.3	0.7	2.0	0.9	0.9	0.8	1.2	-0.6	0.8	0.7	0.7	-0.0	0.9	0.8	0.7	0.4	0.7	0.8	0.8	0.8	0.0	0.8	1.0	1.4	0.9	0.8	0.5
Illnesses of siblings: Diabetes	0.3	0.3	0.9	-0.6	-0.4	-0.6	-0.5	-0.6	-0.6	-0.6	-0.5	-0.7	-0.6	-0.5	-0.6	0.0	-0.6	-0.1	-0.4	-0.6	-0.6	-0.6	-0.5	1.0	-0.6	-0.2	-0.8
Medication for cholesterol	0.3	0.4	4.0	0.6	-0.0	0.5	2.0	0.8	0.5	0.6	0.5	0.8	0.4	0.5	0.6	0.6	0.6	0.3	0.3	0.4	0.5	0.5	0.6	-0.5	0.5	-0.1	0.4
Medication: Paracetamol	0.3	0.5	1.3	-0.6	-0.6	-0.7	-0.2	-1.1	-0.7	-0.6	-0.7	0.4	-0.7	-0.7	-0.7	-1.0	-0.6	-0.3	-0.8	-0.7	-1.0	-0.7	-0.5	-0.1	-0.6	-0.7	-0.8
Leg fat percentage (left)	0.3	1.0	2.8	-0.8	-0.6	-0.9	-1.3	-1.5	-0.9	-0.9	-1.0	-0.6	-0.9	-1.0	-1.0	-1.1	-0.9	-0.9	-1.1	-1.0	-1.7	-0.9	-1.2	-0.1	-1.2	-0.6	-1.3
Average weekly beer plus cider intake	0.3	0.4	1.5	-0.6	-0.5	-0.6	-0.8	-0.8	-0.6	-0.6	-0.6	0.2	-0.7	-0.6	-0.6	-1.0	-0.6	-0.8	-0.5	-0.7	-0.2	-0.7	-0.4	-1.2	-0.4	-0.9	-0.5
Irritability	0.3	0.5	1.5	0.9	0.6	0.8	0.2	0.3	0.8	0.8	0.8	0.4	0.8	0.8	0.8	0.3	0.8	0.3	0.7	0.9	0.4	0.8	1.2	0.1	1.2	0.7	0.7
Risk taking	0.3	0.5	1.6	0.7	0.8	0.6	0.5	0.1	0.6	0.5	0.6	-0.9	0.8	0.6	0.6	0.4	0.5	0.9	0.7	0.9	-0.0	0.6	1.2	0.4	1.3	0.5	0.8
Age started oral contraceptive pill	0.3	0.3	2.7	0.4	0.5	0.4	0.4	1.6	0.3	0.3	0.4	-0.3	0.5	0.4	0.3	0.7	0.3	-0.1	0.6	0.6	0.3	0.4	0.8	0.5	0.8	0.8	0.4
Commuting to job workplace: Cycle	0.3	0.4	0.9	-0.8	-0.8	-0.6	-0.4	-0.2	-0.6	-0.7	-0.6	-0.7	-0.6	-0.6	-0.6	-0.4	-0.7	-0.5	-0.4	-0.6	-0.3	-0.6	-1.0	-0.5	-1.0	-0.8	-0.7
Depressed Affect (Nagel 2018)	0.2	0.4	2.2	-0.4	0.2	-0.4	-1.0	-0.9	-0.4	-0.4	-0.4	-0.3	-0.3	-0.4	-0.7	-0.5	-0.4	-0.4	-0.2	-0.4	-1.5	-0.4	-0.5	-0.5	-0.3	-0.3	-1.1
Bipolar Disorder (2011)	0.2	0.2	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	0.3	1.0	0.0	1.1	0.9	0.8	0.6
HDL Cholesterol	0.2	0.3	2.0	-0.2	-0.8	-0.2	1.4	0.8	-0.2	-0.2	-0.3	0.6	-0.2	-0.3	-0.0	-0.9	-0.2	-0.6	-0.5	-0.2	-0.1	-0.3	-0.2	-0.9	-0.1	-0.2	0.2
LDL Cholesterol	0.2	0.4	2.3	-0.7	-1.1	-0.6	-0.6	-0.4	-0.7	-0.8	-0.6	-1.5	-0.3	-0.5	-0.5	0.0	-0.8	0.0	-0.2	-0.3	-0.6	-0.6	-0.3	0.5	-0.5	-0.2	-0.3
Lupus	0.2	0.3	1.6	0.4	-0.3	0.4	0.8	-1.2	0.3	0.3	0.4	1.1	0.4	0.4	0.3	-0.3	0.3	0.5	0.5	0.4	0.4	0.3	0.3	-0.5	0.3	-0.2	0.3
Rheumatoid Arthritis	0.2	0.2	1.1	0.5	0.3	0.4	0.4	0.2	0.4	0.4	0.4	0.5	0.4	0.4	0.5	0.7	0.4	-0.0	0.3	0.4	1.0	0.4	0.8	0.0	0.8	-0.2	0.5
Blood Eosinophil Count	0.2	1.3	4.5	1.0	2.0	1.0	-0.9	0.4	0.9	1.0	0.9	2.1	0.7	0.9	0.8	1.3	1.0	0.9	0.8	0.7	0.6	0.9	0.9	1.0	0.8	1.8	1.8
Number of treatments/medications taken	0.2	0.4	2.4	0.5	1.5	0.5	-1.0	-0.9	0.5	0.5	0.5	-0.8	0.6	0.5	0.2	0.3	0.5	0.7	0.4	0.5	-0.6	0.5	0.6	0.8	0.5	0.4	0.2
Relative age of first facial hair	0.2	0.5	2.3	0.5	0.5	0.4	1.1	0.6	0.4	0.4	0.5	0.1	0.5	0.5	0.5	0.7	0.4	0.9	0.5	0.6	0.0	0.5	0.7	1.3	0.5	1.5	0.8
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.6	0.5	0.4	0.4	-0.1	0.1	0.4	0.5	0.4	-0.4	0.4	0.4	0.4	0.6	0.5	0.2	0.3	0.4	0.5	0.4	0.5	-0.0	0.8	0.2	0.4
Medication: Metformin	0.2	0.2	3.1	0.4	0.4	0.3	0.4	1.8	0.3	0.4	0.3	-0.5	0.2	0.3	0.3	0.4	0.4	0.1	0.2	0.3	-0.1	0.3	0.3	-0.2	0.5	0.1	-0.0
Maternal smoking around birth	0.2	0.2	1.3	0.2	-0.2	0.1	0.3	-0.7	0.1	0.1	0.1	1.1	0.1	0.1	0.2	-0.8	0.1	-0.1	0.2	0.2	1.1	0.1	0.6	-0.6	0.6	-0.3	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.4	-0.7	-1.2	-0.6	0.1	-0.1	-0.6	-0.5	-0.6	0.0	-0.8	-0.6	-0.4	-0.8	-0.5	-0.7	-0.8	-0.9	0.3	-0.7	-0.5	-1.1	-0.6	-1.5	-0.8
Trunk fat mass	0.2	0.9	3.0	-0.8	-0.4	-0.8	-1.7	-1.0	-0.8	-0.8	-0.9	-0.6	-0.8	-0.9	-0.9	-0.7	-0.8	-0.8	-1.0	-0.9	-1.3	-0.8	-1.3	0.1	-1.3	-0.3	-1.0
Number of incorrect matches in round	0.2	0.4	2.7	0.5	1.0	0.4	0.1	-1.7	0.4	0.4	0.4	0.9	0.4	0.4	0.3	-0.4	0.4	0.4	0.5	0.4	0.4	0.4	0.5	0.4	0.6	1.0	0.6
Had menopause	0.2	0.2	1.3	-0.4	0.0	-0.4	-0.6	-1.1	-0.4	-0.4	-0.3	-0.3	-0.2	-0.3	-0.5	-0.6	-0.4	-0.2	-0.1	-0.2	-0.2	-0.3	-0.4	-0.8	-0.2	-0.3	-0.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.0	0.5	1.0	0.6	0.4	0.6	0.6	0.6	0.6	0.2	0.7	0.6	0.5	-0.5	0.6	0.7	0.6	0.6	-0.3	0.7	0.1	0.3	0.2	0.3	-0.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.4	0.0	1.0	0.0	-1.2	0.7	0.0	-0.1	0.1	-0.1	0.3	0.1	-0.1	0.4	-0.1	0.4	0.4	0.4	-0.1	0.1	0.4	0.6	0.5	0.6	0.4
Fluid intelligence score	0.2	0.3	4.5	0.0	-0.4	-0.1	1.3	2.1	-0.1	-0.1	-0.1	0.2	-0.1	-0.1	0.1	0.2	-0.1	-0.2	0.0	-0.0	0.8	-0.1	0.0	0.3	0.0	-0.7	0.0
Arm fat percentage (right)	0.2	0.7	2.2	-0.7	-0.3	-0.7	-1.5	-1.3	-0.7	-0.7	-0.8	-0.7	-0.7	-0.8	-0.8	-0.6	-0.7	-0.6	-0.9	-0.7	-1.3	-0.7	-1.1	0.3	-1.2	-0.2	-1.0
Father’s age at death	0.2	0.3	2.2	0.3	-0.1	0.2	1.1	0.1	0.2	0.2	0.2	0.9	0.2	0.2	0.4	0.1	0.2	0.5	0.3	0.3	1.5	0.1	0.8	-0.2	0.8	-0.0	0.7
Noisy workplace	0.2	0.2	0.8	-0.4	-0.8	-0.4	0.2	-0.7	-0.4	-0.4	-0.5	-0.3	-0.4	-0.5	-0.3	-0.7	-0.4	-0.8	-0.6	-0.4	-0.0	-0.4	-0.3	-0.9	-0.4	-0.3	-0.3
Mouth/teeth dental problems: Dentures	0.2	0.3	1.2	-0.3	-0.2	-0.2	-1.0	-0.7	-0.2	-0.2	-0.3	-1.1	-0.2	-0.3	-0.4	-0.2	-0.2	-0.0	-0.3	-0.3	-0.9	-0.2	-0.8	-0.4	-0.6	-0.5	-0.6
Asthma	0.2	0.3	1.1	0.5	0.9	0.5	-0.5	0.9	0.4	0.5	0.5	-0.6	0.4	0.5	0.2	0.2	0.5	0.6	0.5	0.4	-0.6	0.4	0.7	1.0	0.6	0.3	0.1
Illnesses of mother	0.2	0.2	1.1	0.0	-0.9	-0.1	0.6	-1.0	-0.1	-0.0	-0.0	1.1	-0.1	-0.0	0.3	-0.2	-0.0	0.0	-0.1	-0.1	1.0	-0.1	0.3	-0.7	0.2	-0.7	0.2
Birth weight of first child	0.2	0.4	0.7	-0.6	-0.8	-0.7	-0.2	0.6	-0.7	-0.7	-0.7	-0.7	-0.6	-0.7	-0.5	0.0	-0.7	-0.8	-0.5	-0.5	0.3	-0.7	-0.4	-0.9	-0.5	-0.7	-0.1
Peak expiratory flow (PEF)	0.2	0.4	2.8	0.2	-1.1	-0.1	1.7	1.6	-0.1	-0.1	-0.0	0.6	0.0	-0.0	0.3	-0.0	-0.1	-0.1	0.2	0.2	0.8	-0.0	0.7	0.1	0.4	-0.3	0.3
Pulse wave reflection index	0.2	0.3	2.1	0.3	0.5	0.4	-0.1	1.4	0.4	0.4	0.5	-0.3	0.6	0.5	0.4	1.0	0.4	0.1	0.7	0.5	0.5	0.4	0.3	0.4	0.5	0.4	0.5
Glaucoma (self-reported)	0.2	0.2	1.1	0.4	0.2	0.4	0.7	0.0	0.5	0.4	0.4	1.1	0.6	0.4	0.6	-0.4	0.4	0.5	0.4	0.4	0.5	0.5	-0.1	0.2	0.3	0.1	0.3
Body fat percentage	0.2	0.7	2.2	-0.7	-0.2	-0.7	-1.5	-1.2	-0.7	-0.7	-0.8	-0.6	-0.7	-0.8	-0.9	-0.6	-0.7	-0.6	-0.9	-0.7	-1.4	-0.7	-0.9	0.3	-1.0	-0.1	-0.9
Medication: Ibuprofen	0.2	0.2	1.6	0.4	0.3	0.3	0.1	0.9	0.3	0.3	0.3	-0.4	0.3	0.3	0.3	0.2	0.3	0.2	0.3	0.5	0.3	0.3	1.3	0.1	0.9	0.1	0.4
Heart disease (mother)	0.2	0.2	0.9	-0.4	0.3	-0.2	-0.7	0.2	-0.3	-0.2	-0.3	-0.6	-0.4	-0.3	-0.5	-0.1	-0.2	-0.8	-0.5	-0.5	-0.9	-0.3	-0.6	-0.5	-0.3	-0.5	-0.4
Arm predicted mass (right)	0.2	0.8	1.9	-0.8	-0.7	-0.8	-1.4	-0.8	-0.7	-0.7	-0.7	-0.5	-0.8	-0.7	-0.7	-1.0	-0.7	-0.7	-0.6	-0.9	-1.2	-0.8	-1.2	-0.7	-1.1	-1.0	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.6	0.3	-0.4	0.1	0.8	-0.1	0.1	0.1	0.1	1.3	0.1	0.1	0.4	0.1	0.1	-0.1	0.2	0.1	1.2	0.1	0.7	-0.3	0.5	0.1	0.6
Medication: Aspirin	0.2	0.2	1.1	-0.2	-0.2	0.1	0.2	1.0	0.1	0.1	-0.0	-1.0	0.0	-0.0	-0.0	0.1	0.1	-0.2	-0.2	-0.2	-1.1	0.1	-0.6	-0.4	-0.6	-0.4	-0.6
Average weekly red wine intake	0.2	0.4	2.2	-0.3	-0.8	-0.5	0.2	-1.5	-0.5	-0.5	-0.6	-1.0	-0.5	-0.6	-0.6	-0.1	-0.5	-0.5	-0.6	-0.4	-0.4	-0.5	0.5	-0.1	0.2	-0.7	-0.7
Medication: Aspirin	0.2	0.2	0.9	0.3	0.1	0.6	0.5	0.9	0.6	0.6	0.5	-0.8	0.5	0.5	0.5	0.6	0.6	0.2	0.2	0.2	-0.4	0.6	-0.4	0.2	-0.3	-0.0	-0.2
Illnesses of father: None of the above (group 1)	0.2	0.3	1.4	-0.6	-1.2	-0.5	0.0	-1.1	-0.5	-0.5	-0.4	-0.3	-0.4	-0.4	-0.3	0.0	-0.5	-0.6	-0.2	-0.3	0.0	-0.4	-0.3	-0.9	-0.4	-0.8	-0.5
Arm fat mass (left)	0.2	0.7	2.6	-0.7	-0.5	-0.7	-1.6	-1.1	-0.7	-0.7	-0.7	-0.5	-0.6	-0.7	-0.8	-0.7	-0.7	-0.6	-0.8	-0.7	-1.3	-0.7	-1.2	0.1	-1.3	-0.4	-1.0
Eye problems/disorders: Glaucoma	0.2	0.3	1.0	-0.4	-0.7	-0.4	0.2	1.0	-0.4	-0.4	-0.4	0.6	-0.3	-0.4	-0.3	-0.9	-0.4	-0.5	-0.4	-0.4	-0.0	-0.4	-0.8	-0.1	-0.5	-0.6	-0.6
High cholesterol (Self-reported)	0.2	0.4	2.2	-0.4	-0.2	-0.4	-1.2	-0.8	-0.5	-0.4	-0.5	-0.1	-0.6	-0.5	-0.7	-0.9	-0.4	-0.6	-0.7	-0.6	-1.5	-0.5	-0.4	-0.3	-0.4	-0.1	-0.9
Basal metabolic rate	0.2	0.9	1.9	-0.9	-0.9	-0.8	-1.4	-0.9	-0.8	-0.8	-0.8	-0.7	-0.8	-0.8	-0.8	-1.0	-0.8	-0.8	-0.8	-0.9	-1.1	-0.8	-1.4	-0.6	-1.4	-1.0	-1.2
Arm predicted mass (left)	0.2	1.2	2.0	-1.0	-1.1	-0.9	-1.4	-1.2	-0.9	-0.9	-0.9	-0.8	-1.0	-0.9	-0.9	-1.2	-0.9	-0.9	-0.8	-1.1	-1.3	-0.9	-1.4	-0.9	-1.4	-1.2	-1.4
Bipolar Disorder or Schizophrenia	0.1	0.2	2.6	0.1	0.3	0.1	0.6	1.6	0.1	0.1	0.0	-0.5	-0.0	0.0	-0.1	0.6	0.1	-0.1	-0.1	-0.1	-0.7	0.1	-0.4	0.4	-0.3	0.2	-0.2
Intelligence (Savage-Jansen 2018)	0.1	0.2	1.4	0.3	-0.2	0.3	1.1	0.6	0.2	0.2	0.3	0.8	0.3	0.3	0.5	0.1	0.2	0.1	0.4	0.3	1.2	0.4	0.4	0.9	0.2	-0.0	0.4
Schizophrenia (2018)	0.1	0.2	1.0	-0.4	-0.1	-0.4	-0.3	0.9	-0.4	-0.4	-0.4	-0.5	-0.3	-0.4	-0.5	0.0	-0.4	-0.7	-0.4	-0.4	-1.0	-0.3	-0.6	-0.3	-0.6	-0.3	-0.4
Irritable Bowel Disease (IBD)	0.1	0.3	1.6	-0.5	0.0	-0.5	0.6	0.6	-0.5	-0.6	-0.5	-1.0	-0.4	-0.5	-0.7	-0.1	-0.6	-0.7	-0.4	-0.3	-1.3	-0.5	-0.5	0.6	-0.5	-0.1	-0.4
Major Depression (MDD)	0.1	0.1	0.3	-0.1	-0.5	-0.2	0.4	0.1	-0.3	-0.2	-0.3	0.1	-0.3	-0.3	-0.3	0.2	-0.2	-0.6	-0.5	-0.3	-0.4	-0.2	-0.1	-0.3	-0.4	-0.1	-0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.2	2.6	0.2	0.1	0.1	0.8	1.6	0.1	0.1	0.1	0.1	0.1	0.1	0.3	0.1	0.1	0.0	0.3	0.1	0.9	0.1	0.1	1.0	-0.0	-0.2	0.4
Breast Cancer	0.1	0.2	2.1	0.0	-0.4	-0.0	-0.7	-1.4	-0.0	-0.1	-0.0	-0.5	0.3	0.0	-0.0	0.1	-0.1	0.1	0.2	0.4	-0.5	0.1	0.4	-0.2	0.4	-0.1	-0.3
Age at First Birth	0.1	0.2	0.9	0.4	0.4	0.4	0.5	-0.4	0.4	0.4	0.3	0.2	0.3	0.3	0.3	0.6	0.4	0.1	-0.0	0.2	0.9	0.2	0.4	0.5	0.2	0.3	0.4
Body Mass Index (BMI) (2010)	0.1	0.1	1.0	0.2	0.4	0.2	-0.6	-0.4	0.2	0.2	0.3	-0.1	0.2	0.3	0.3	-0.1	0.2	0.2	0.4	0.3	1.0	0.2	0.1	-0.2	0.1	-0.0	0.0
Crohns Disease (2012)	0.1	0.1	1.2	-0.1	0.0	0.1	1.1	-0.7	0.1	0.1	0.1	-0.0	0.2	0.1	-0.0	-0.3	0.1	-0.1	0.2	0.1	-0.2	0.1	-0.4	0.4	-0.3	-0.2	-0.1
Neuroticism (2016)	0.1	0.2	0.9	-0.3	0.1	-0.4	-0.7	-0.2	-0.4	-0.4	-0.4	-0.3	-0.2	-0.3	-0.6	-0.1	-0.4	-0.2	-0.2	-0.3	-1.0	-0.4	-0.3	0.3	-0.3	0.0	-0.6
Primary Biliary Cirrhosis	0.1	0.2	2.7	0.0	0.4	0.2	0.1	-1.6	0.2	0.2	0.1	0.2	0.1	0.1	0.1	-0.0	0.2	0.6	-0.1	0.0	-0.3	0.2	-0.3	0.0	-0.1	-0.1	-0.1
Ulcerative Colitis	0.1	0.1	1.1	-0.2	0.4	-0.0	-0.2	0.0	-0.1	-0.0	-0.1	-0.3	-0.2	-0.1	-0.2	0.1	-0.0	-0.2	-0.2	-0.3	-0.5	-0.1	-1.0	0.2	-0.8	-0.0	-0.4
Blood Platelet Count	0.1	1.5	11.8	-0.8	0.2	-0.4	1.1	-2.9	-0.5	-0.4	-0.5	0.4	-0.5	-0.5	-0.7	-1.7	-0.4	3.4	-0.7	-0.8	0.1	-0.5	-1.5	-1.0	-1.3	-0.8	-1.0
Blood Red Count	0.1	0.9	4.8	0.4	1.1	0.2	-1.0	1.8	0.2	0.1	0.4	-1.3	0.7	0.4	-0.0	1.6	0.1	-0.0	0.9	0.8	-0.8	0.3	0.6	2.2	0.5	1.4	0.6
Heel T-Score	0.1	0.9	2.0	0.8	1.4	0.9	0.0	-0.4	0.9	0.9	1.0	0.6	1.1	1.0	0.9	0.8	0.9	1.4	1.1	1.0	0.8	0.9	0.6	1.0	0.7	1.2	1.1
BMI	0.1	0.4	1.2	0.7	0.3	0.6	-0.1	-0.4	0.6	0.6	0.6	1.1	0.6	0.6	0.7	0.9	0.6	0.4	0.7	0.7	0.7	0.6	0.7	0.3	0.6	0.4	0.4
Systolic Blood Pressure	0.1	0.5	2.2	-0.7	-0.6	-0.5	0.6	-0.1	-0.5	-0.4	-0.6	0.1	-0.7	-0.6	-0.5	-1.5	-0.4	-0.7	-0.8	-0.8	0.1	-0.6	-0.9	-0.8	-0.7	-1.1	-0.5
Lung FVC	0.1	0.5	2.9	0.3	-0.6	0.4	0.8	0.0	0.4	0.5	0.4	1.7	0.3	0.4	0.7	0.7	0.5	0.1	0.3	0.3	1.5	0.4	0.3	-1.2	0.6	-0.7	0.6
Hearing difficulty/problems: Yes	0.1	0.1	0.4	0.1	0.4	0.1	0.5	0.5	0.2	0.1	0.2	-0.6	0.2	0.2	0.1	0.2	0.1	-0.5	0.3	0.1	0.0	0.1	-0.6	-0.1	-0.3	0.2	-0.0
Ever used hormone-replacement therapy (HRT)	0.1	0.2	1.4	-0.5	-0.5	-0.1	0.4	-0.2	-0.1	-0.2	-0.1	-0.1	0.1	-0.1	-0.1	-0.3	-0.2	-0.2	0.2	-0.1	0.2	-0.1	-1.2	-0.7	-0.7	-0.4	-0.6
Systolic blood pressure, automated reading	0.1	0.2	0.8	-0.5	-0.3	-0.4	0.0	-0.1	-0.4	-0.3	-0.4	0.0	-0.4	-0.4	-0.4	-0.9	-0.3	-0.4	-0.4	-0.5	-0.2	-0.4	-0.5	-0.4	-0.3	-0.5	-0.4
Vitamin and mineral supplements	0.1	0.2	0.6	-0.3	-0.8	-0.5	-0.5	-0.0	-0.5	-0.5	-0.4	0.5	-0.3	-0.4	-0.3	-0.6	-0.5	-0.3	-0.2	-0.2	-0.6	-0.5	0.1	0.0	-0.1	-0.3	0.2
Diabetes (mother)	0.1	0.1	0.3	0.3	0.6	0.5	0.2	0.3	0.4	0.6	0.3	0.2	0.1	0.3	0.3	0.4	0.6	0.5	-0.1	-0.1	0.5	0.4	-0.3	0.3	-0.1	0.1	-0.2
Trunk fat percentage	0.1	0.5	2.5	-0.6	-0.1	-0.6	-1.6	-1.0	-0.6	-0.7	-0.7	-0.4	-0.6	-0.7	-0.8	-0.4	-0.7	-0.6	-0.8	-0.6	-1.1	-0.6	-0.9	0.4	-0.9	0.0	-0.7
Hand grip strength (right)	0.1	0.3	0.8	-0.7	-0.9	-0.7	-0.2	0.6	-0.6	-0.6	-0.6	-0.4	-0.6	-0.6	-0.5	-0.4	-0.6	-0.5	-0.5	-0.5	-0.6	-0.6	-0.3	-0.7	-0.4	-0.8	-0.4
Townsend deprivation index at recruitment	0.1	0.1	0.5	-0.1	-0.7	-0.0	0.5	-0.5	-0.0	-0.0	-0.1	0.3	-0.1	-0.1	0.0	-0.1	-0.0	-0.4	-0.3	-0.2	-0.1	-0.0	-0.7	-0.4	-0.4	-0.6	-0.5
Fed-up feelings	0.1	0.2	1.7	-0.2	0.4	-0.2	-0.6	-0.2	-0.2	-0.2	-0.1	-0.7	-0.2	-0.1	-0.5	-0.4	-0.2	-0.7	-0.0	-0.2	-1.3	-0.2	-0.5	-0.1	-0.3	-0.1	-0.6
Serious illness, injury or assault to yourself	0.1	0.2	1.0	-0.2	0.5	-0.3	-0.8	-0.1	-0.2	-0.3	-0.4	-0.1	-0.2	-0.3	-0.5	-0.5	-0.3	-0.2	-0.5	-0.3	-1.0	-0.3	-0.5	0.2	-0.4	-0.0	-0.4
Multivitamins +/- minerals	0.1	0.1	0.5	0.1	0.3	0.3	0.7	-0.1	0.3	0.4	0.3	-0.4	0.1	0.3	0.2	0.2	0.4	0.1	0.1	-0.0	0.3	0.3	-0.3	-0.4	-0.1	-0.1	-0.3
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.2	0.2	-0.1	0.3	0.7	-0.4	0.3	0.3	0.3	1.1	0.3	0.3	0.4	0.0	0.3	-0.0	0.2	0.2	0.8	0.3	-0.0	-0.7	0.1	-0.3	0.5
Alcohol usually taken with meals	0.1	0.2	1.9	0.3	-0.2	0.2	1.4	0.1	0.2	0.3	0.2	0.6	0.1	0.2	0.3	0.1	0.3	0.3	0.0	0.1	1.3	0.2	0.1	0.1	0.2	0.1	-0.1
Hearing difficulty/problems with background noise	0.1	0.2	1.4	0.5	0.3	0.4	1.2	-0.3	0.4	0.4	0.5	-0.4	0.5	0.5	0.4	-0.3	0.4	0.2	0.8	0.6	0.1	0.4	0.3	0.5	0.3	0.6	0.1
Hair/balding pattern: Pattern 2	0.1	0.1	0.7	-0.2	-0.5	-0.3	0.1	0.0	-0.3	-0.3	-0.3	-0.1	-0.4	-0.3	-0.2	-0.7	-0.3	-0.9	-0.2	-0.2	0.3	-0.3	0.1	0.0	0.0	-0.3	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.3	-0.4	-0.7	-0.4	0.3	-0.1	-0.4	-0.3	-0.4	0.4	-0.6	-0.4	-0.2	-0.9	-0.3	-0.3	-0.6	-0.7	0.4	-0.5	-0.2	-0.9	-0.3	-1.1	-0.4
Mouth/teeth dental problems	0.1	0.1	1.2	-0.0	0.2	-0.0	-0.1	0.2	-0.0	-0.0	0.0	1.1	0.0	0.0	0.1	0.4	-0.0	0.2	0.2	0.1	0.9	-0.0	0.3	0.0	0.2	0.0	0.3
Medication: Ramipril	0.1	0.1	0.3	-0.0	-0.3	-0.3	0.1	0.5	-0.2	-0.4	-0.2	0.3	0.0	-0.2	-0.2	-0.5	-0.4	0.1	-0.0	0.1	0.1	-0.2	0.3	-0.2	0.2	0.0	0.4
Weight	0.1	0.7	1.9	-0.7	-0.5	-0.7	-1.4	-0.8	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.7	-0.6	-0.7	-0.8	-1.1	-0.7	-1.2	-0.0	-1.2	-0.5	-1.0
Alcohol intake versus 10 years previously	0.1	0.2	1.1	0.2	0.4	0.1	0.6	-0.2	0.1	0.1	0.1	-0.9	0.1	0.1	0.1	0.6	0.1	0.4	0.1	0.2	0.2	0.1	0.5	1.1	0.3	0.9	0.5
Pulse rate	0.1	0.2	1.2	-0.1	-0.1	-0.3	-0.7	-1.1	-0.3	-0.3	-0.3	0.1	-0.2	-0.3	-0.3	-0.9	-0.3	-0.6	-0.4	-0.2	-0.5	-0.3	0.1	-0.4	-0.1	0.0	-0.2
Medication: Cholesterol lowering	0.1	0.2	1.4	-0.3	0.0	-0.3	-0.6	0.1	-0.3	-0.3	-0.4	-0.5	-0.3	-0.4	-0.5	-0.3	-0.3	-0.7	-0.5	-0.3	-1.2	-0.3	-0.4	-0.2	-0.4	-0.2	-0.8
Medication: Lansoprazole	0.1	0.1	1.3	0.2	0.3	-0.0	-0.8	-1.0	0.0	-0.0	-0.0	0.0	-0.0	-0.0	0.0	-0.1	-0.0	-0.5	-0.1	-0.0	0.1	-0.0	-0.1	1.1	-0.1	0.3	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.8	-0.5	-1.3	-0.7	0.3	0.4	-0.6	-0.6	-0.6	0.5	-0.7	-0.6	-0.4	-0.7	-0.6	-0.8	-0.7	-0.6	0.2	-0.6	-0.2	-1.0	-0.3	-0.9	-0.3
Pulse wave Arterial Stiffness index	0.1	0.2	0.8	-0.3	0.0	-0.2	-0.8	0.5	-0.2	-0.1	-0.2	-0.7	-0.3	-0.2	-0.3	0.3	-0.1	-0.9	-0.3	-0.4	-0.2	-0.2	-0.5	-0.5	-0.3	0.0	-0.2
Length of working week for main job	0.1	0.1	1.3	-0.2	-0.2	-0.1	0.0	0.4	-0.1	-0.2	-0.1	0.3	0.0	-0.1	-0.1	0.1	-0.2	0.0	-0.1	-0.0	0.5	-0.1	-0.5	-1.1	-0.2	-0.6	0.2
Exposure to tobacco smoke at home	0.1	0.1	0.6	0.1	0.2	0.1	0.0	0.7	0.1	0.1	0.2	-0.8	0.3	0.2	0.0	-0.2	0.1	-0.0	0.4	0.3	-0.2	0.1	0.2	-0.3	0.5	-0.2	-0.4
Blood clot in the leg (DVT)	0.1	0.2	1.3	-0.1	0.4	-0.2	-1.2	-0.3	-0.2	-0.1	-0.2	0.1	-0.4	-0.2	-0.4	0.4	-0.1	-0.2	-0.4	-0.5	-0.6	-0.2	-0.5	-0.0	-0.6	-0.2	-0.5
Medication: Paracetamol	0.1	0.2	1.4	0.4	-0.1	0.1	0.9	-0.2	0.1	0.1	0.1	1.2	0.2	0.1	0.1	-0.2	0.1	0.6	0.0	0.3	-0.6	0.2	1.0	0.7	0.6	0.1	-0.0
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	2.2	0.3	-0.3	0.3	0.6	0.0	0.3	0.3	0.3	1.5	0.2	0.3	0.5	0.3	0.3	0.4	0.3	0.2	1.1	0.2	0.4	0.1	0.4	-0.0	0.6
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.8	0.1	0.2	-0.1	-0.5	-0.7	-0.1	-0.1	-0.1	-1.3	-0.0	-0.1	-0.2	0.0	-0.1	-0.1	-0.1	0.0	-0.6	-0.1	0.5	0.7	0.3	0.2	0.3
Birth weight	0.1	0.1	0.8	0.1	-0.6	-0.1	0.7	-0.0	-0.1	-0.0	-0.2	0.2	-0.3	-0.2	0.1	0.1	-0.0	0.1	-0.5	-0.3	0.9	-0.1	-0.3	0.6	-0.4	-0.1	0.1
Forced vital capacity (FVC), Best measure	0.1	0.3	1.1	-0.1	-0.9	-0.2	0.5	0.6	-0.2	-0.1	-0.2	1.1	-0.3	-0.2	0.1	-0.0	-0.1	-0.6	-0.3	-0.2	1.0	-0.2	0.4	-1.1	0.3	-0.7	0.3
Arm fat-free mass (right)	0.1	0.4	1.1	-0.5	-0.7	-0.5	-1.1	-0.6	-0.5	-0.5	-0.4	-0.1	-0.5	-0.4	-0.4	-0.8	-0.5	-0.4	-0.3	-0.6	-0.7	-0.5	-0.8	-0.5	-0.8	-0.7	-0.8
Comparative body size at age 10	0.1	0.2	1.3	0.0	-0.9	-0.0	0.5	-1.1	0.0	-0.1	0.1	-0.8	0.2	0.1	0.3	0.0	-0.1	-0.1	0.4	0.4	0.6	0.1	0.7	-0.5	0.6	-0.6	0.2
Pulse wave peak to peak time	0.1	0.1	0.5	0.1	-0.3	-0.1	0.5	-0.7	-0.0	-0.1	-0.1	0.4	0.0	-0.0	0.0	-0.6	-0.1	0.7	0.0	0.1	0.0	-0.0	0.3	0.3	0.1	-0.3	-0.1
Health satisfaction	0.1	0.1	0.4	0.3	0.1	0.3	-0.5	-0.5	0.3	0.2	0.3	-0.3	0.6	0.3	0.3	-0.1	0.2	0.3	0.4	0.5	-0.6	0.4	0.3	0.2	0.3	0.1	0.2
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.4	-0.7	-0.4	-0.1	0.3	-0.4	-0.4	-0.4	-0.1	-0.5	-0.4	-0.4	-0.5	-0.4	-0.5	-0.4	-0.4	0.0	-0.4	0.1	0.0	-0.2	-0.3	-0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.2	1.0	-0.2	0.2	-0.2	-0.1	0.1	-0.2	-0.2	-0.3	-1.0	-0.2	-0.3	-0.4	0.1	-0.2	-0.1	-0.4	-0.3	-0.3	-0.2	-0.5	1.0	-0.4	0.2	-0.6
Medication for pain relief, constipation, heartburn	0.1	0.1	1.0	-0.0	0.1	0.2	0.3	0.1	0.1	0.2	0.2	0.5	-0.1	0.1	0.2	0.1	0.2	-0.1	0.0	-0.2	1.0	0.1	-0.7	-0.1	-0.5	0.3	0.3
Neck or shoulder pain in last month	0.1	0.1	0.8	0.4	0.4	0.2	0.9	0.5	0.2	0.2	0.3	0.5	0.3	0.3	0.1	-0.1	0.2	0.0	0.4	0.3	-0.3	0.3	0.2	0.5	0.2	0.3	-0.3
Medication: Blood pressure	0.1	0.2	2.5	-0.2	0.7	-0.1	-0.5	-0.5	-0.1	-0.2	-0.1	-1.6	0.0	-0.1	-0.3	0.0	-0.2	-0.0	0.1	0.0	-0.4	-0.1	-0.4	0.1	-0.3	0.2	-0.2
Mean time to correctly identify matches	0.1	0.3	2.8	-0.3	0.6	-0.3	-1.7	-0.6	-0.3	-0.3	-0.4	0.4	-0.3	-0.4	-0.6	-0.5	-0.3	-0.3	-0.4	-0.3	-0.7	-0.3	-0.4	-0.2	-0.2	0.1	-0.4
Alcohol intake frequency.	0.1	0.1	0.5	0.2	0.3	0.4	0.7	-0.3	0.4	0.3	0.4	0.6	0.5	0.4	0.3	0.0	0.3	0.4	0.4	0.4	-0.1	0.4	0.1	0.4	0.0	0.3	-0.0
Suffer from ‘nerves’	0.1	0.2	0.6	-0.3	-0.1	-0.3	-0.4	-0.6	-0.3	-0.3	-0.3	0.4	-0.4	-0.3	-0.5	-0.8	-0.3	-0.1	-0.4	-0.4	-0.7	-0.3	-0.3	-0.2	-0.3	-0.3	-0.8
Smoking status: Previous	0.1	0.1	1.7	-0.0	0.4	0.1	-0.1	-1.3	0.1	0.1	-0.0	0.3	0.0	-0.0	-0.1	-0.5	0.1	0.2	-0.2	-0.1	-0.1	0.0	-0.7	-0.0	-0.4	0.1	-0.6
Whole body fat-free mass	0.1	0.7	1.5	-0.8	-0.8	-0.7	-1.2	-0.8	-0.7	-0.7	-0.7	-0.6	-0.7	-0.7	-0.6	-0.9	-0.7	-0.7	-0.6	-0.8	-0.9	-0.7	-1.2	-0.6	-1.2	-0.9	-1.1
Arm fat percentage (left)	0.1	0.5	1.8	-0.5	-0.1	-0.5	-1.4	-1.0	-0.5	-0.5	-0.6	-0.6	-0.4	-0.6	-0.6	-0.5	-0.5	-0.4	-0.7	-0.5	-1.3	-0.5	-0.9	0.4	-1.0	-0.0	-0.7
Breast cancer (self-reported)	0.1	0.1	0.9	-0.1	0.2	-0.1	-0.5	-0.4	-0.1	-0.1	0.0	-0.1	0.2	0.0	-0.1	0.4	-0.1	0.2	0.3	0.2	0.1	0.0	0.2	-0.9	0.3	-0.5	-0.1
Asthma (self-reported)	0.1	0.2	0.9	0.3	0.7	0.3	-0.8	0.9	0.3	0.3	0.3	-0.9	0.2	0.3	0.1	0.1	0.3	0.4	0.3	0.3	-0.7	0.3	0.6	0.6	0.5	0.1	0.0
Osteoarthritis (self-reported)	0.1	0.1	1.0	0.2	-0.5	-0.0	0.0	-1.0	-0.0	-0.0	-0.0	0.6	0.0	-0.0	0.1	-0.1	-0.0	-0.4	-0.0	0.1	0.5	-0.0	0.6	-0.6	0.3	-0.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.5	0.5	-0.1	0.4	1.0	0.3	0.4	0.4	0.4	1.2	0.2	0.4	0.5	0.8	0.4	0.4	0.4	0.3	0.4	0.4	0.4	0.3	0.4	0.4	0.6
Whole body water mass	0.1	0.8	1.6	-0.9	-0.9	-0.8	-1.1	-0.8	-0.8	-0.8	-0.7	-0.6	-0.8	-0.7	-0.7	-1.0	-0.8	-0.7	-0.7	-0.9	-0.9	-0.8	-1.3	-0.6	-1.3	-1.0	-1.1
Average weekly champagne plus white wine intake	0.1	0.2	0.8	0.3	-0.2	0.3	0.9	0.0	0.3	0.3	0.3	0.9	0.3	0.3	0.5	0.1	0.3	0.7	0.3	0.2	0.6	0.3	-0.1	-0.1	-0.1	-0.1	0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	-0.1	-0.2	-0.3	-0.4	-0.5	-0.3	-0.4	-0.3	-0.2	-0.1	-0.3	-0.3	-0.3	-0.4	-0.4	-0.1	-0.0	-0.5	-0.2	0.1	0.1	0.1	-0.3	-0.4
Illnesses of father: High blood pressure	0.1	0.1	1.0	-0.2	0.1	-0.1	-0.7	-0.5	-0.1	-0.2	-0.1	-1.0	0.1	-0.0	-0.1	-0.2	-0.2	0.3	0.2	0.0	0.2	-0.1	-0.3	0.8	-0.3	0.3	0.0
Arm fat-free mass (left)	0.1	0.5	1.1	-0.6	-0.7	-0.6	-1.1	-0.7	-0.5	-0.6	-0.5	-0.4	-0.6	-0.5	-0.5	-0.8	-0.6	-0.6	-0.5	-0.7	-0.8	-0.6	-1.1	-0.5	-1.0	-0.8	-1.0
Ever depressed for a whole week	0.1	0.2	0.4	0.2	0.5	0.5	0.7	0.6	0.5	0.5	0.5	-0.3	0.4	0.5	0.3	-0.4	0.5	0.4	0.4	0.2	-0.6	0.4	-0.4	0.3	-0.2	-0.3	-0.5
Pain experienced in last month	0.1	0.2	1.2	0.2	0.8	0.3	-1.1	0.6	0.3	0.3	0.2	-0.3	0.2	0.2	0.1	0.9	0.3	-0.1	0.1	0.2	0.5	0.2	-0.1	0.5	0.2	0.8	0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.9	-0.2	0.0	-0.3	-0.8	-1.0	-0.3	-0.3	-0.2	0.0	-0.2	-0.2	-0.3	-0.2	-0.3	-0.4	-0.1	-0.2	-0.6	-0.3	0.1	-0.2	-0.1	0.4	0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	1.3	-0.1	0.3	-0.1	-1.1	-0.7	-0.1	-0.0	-0.1	0.0	-0.3	-0.1	-0.3	0.6	-0.0	-0.2	-0.3	-0.4	-0.5	-0.1	-0.6	-0.0	-0.7	-0.2	-0.6
Impedance of whole body	0.1	0.8	1.3	-1.0	-0.9	-1.0	-0.1	-0.0	-1.1	-1.0	-1.1	-0.0	-1.0	-1.1	-1.0	-1.0	-1.0	-0.9	-1.1	-0.9	0.0	-1.0	-0.6	-1.1	-0.6	-0.8	-0.4
Crohns Disease (2017)	0.0	0.1	0.6	-0.1	-0.1	-0.2	0.7	0.2	-0.2	-0.2	-0.1	-0.6	-0.0	-0.1	-0.3	0.0	-0.2	-0.4	-0.0	0.1	-0.7	-0.2	0.2	0.6	0.2	-0.1	0.0
Hair Pigment	0.0	0.6	3.2	0.5	1.8	0.7	-0.3	0.8	0.6	0.7	0.6	-0.6	0.6	0.6	0.2	0.4	0.7	0.7	0.5	0.5	-0.6	0.6	0.7	1.7	0.6	1.4	0.4
Tanning	0.0	0.4	1.4	0.6	0.7	0.5	0.2	0.9	0.5	0.4	0.6	-0.2	0.7	0.6	0.5	0.6	0.4	0.6	0.8	0.7	0.2	0.5	1.2	0.6	1.1	0.4	0.6
Hand grip strength (left)	0.0	0.1	0.5	-0.1	-0.3	-0.1	0.2	0.1	-0.1	-0.1	-0.1	0.7	-0.2	-0.1	-0.0	-0.5	-0.1	0.0	-0.1	-0.2	0.4	-0.2	-0.1	-0.4	-0.0	-0.3	0.0
Leg fat-free mass (left)	0.0	0.1	0.8	-0.3	-0.2	-0.2	-0.9	-0.4	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.3	-0.2	-0.2	-0.2	-0.3	-0.5	-0.2	-0.7	-0.0	-0.7	-0.3	-0.5
Sitting height	0.0	0.3	2.1	-0.5	-0.5	-0.4	0.6	1.5	-0.4	-0.3	-0.4	0.4	-0.6	-0.4	-0.3	-0.8	-0.3	-0.4	-0.5	-0.6	-0.1	-0.4	-0.8	-0.6	-0.8	-0.4	-0.2
Body mass index (BMI)	0.0	0.2	0.9	0.0	0.2	-0.0	-0.9	-0.9	0.0	-0.0	-0.0	-0.3	0.0	-0.0	-0.1	0.1	-0.0	-0.0	-0.0	-0.0	-0.9	-0.0	-0.3	0.7	-0.4	0.2	-0.4
Leg predicted mass (left)	0.0	0.1	0.8	-0.3	-0.2	-0.2	-0.9	-0.4	-0.2	-0.2	-0.2	-0.3	-0.2	-0.2	-0.2	-0.3	-0.2	-0.3	-0.2	-0.3	-0.5	-0.2	-0.7	0.0	-0.7	-0.3	-0.5
Hip circumference	0.0	0.1	0.7	0.1	0.2	0.1	0.1	-0.1	0.2	0.1	0.1	-0.4	0.2	0.1	0.1	0.1	0.1	-0.0	0.1	0.1	-0.7	0.2	-0.6	0.8	-0.6	0.3	-0.5
Impedance of arm (left)	0.0	0.2	0.5	-0.6	-0.4	-0.6	-0.1	0.0	-0.6	-0.6	-0.7	-0.1	-0.5	-0.7	-0.6	-0.3	-0.6	-0.5	-0.7	-0.4	0.4	-0.6	-0.1	-0.4	-0.2	-0.2	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.1	0.2	0.2	0.2	0.1	-0.1	0.2	0.2	0.1	0.2	-0.2	0.3	0.2	0.1	0.4	0.1	-0.1	0.4	0.3	0.2	0.2	0.1	0.5	0.1	0.4	0.3
Comparative height size at age 10	0.0	0.2	1.2	-0.5	-0.3	-0.4	-1.0	1.1	-0.4	-0.5	-0.4	-0.4	-0.2	-0.4	-0.4	-0.2	-0.5	-0.0	-0.1	-0.1	0.0	-0.4	-0.1	-0.4	0.0	-0.1	0.0
Leg fat-free mass (right)	0.0	0.1	0.6	-0.3	-0.1	-0.2	-0.8	-0.4	-0.1	-0.1	-0.1	-0.1	-0.2	-0.1	-0.1	-0.3	-0.1	-0.2	-0.1	-0.2	-0.5	-0.1	-0.7	0.1	-0.7	-0.2	-0.4
Leg predicted mass (right)	0.0	0.1	0.6	-0.3	-0.0	-0.1	-0.8	-0.5	-0.1	-0.1	-0.1	-0.1	-0.2	-0.1	-0.1	-0.3	-0.1	-0.2	-0.1	-0.2	-0.5	-0.1	-0.7	0.0	-0.7	-0.2	-0.4

Hub : Genes

ZNF496

Models

Trait associations