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chr2:168,949,234-170,419,444

Best TWAS P=5.07e-35 · Best GWAS P=8.7e-32 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NOSTRIN	0.14	0.13	lasso	4	0.12	1.9e-14	10.88	-12.3	5.1e-35	0.72	0.95	0.05	TRUE
14	The Cancer Genome Atlas	Glioblastoma Multiforme	NOSTRIN	0.25	0.01	blup	55	0.08	2.0e-03	9.15	-9.3	8.6e-21	0.76	0.01	0.63	TRUE
22	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NOSTRIN	0.05	0.00	blup	55	0.01	1.1e-02	9.15	-9.3	1.7e-20	0.71	0.02	0.50	TRUE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NOSTRIN	0.09	0.03	enet	5	0.09	1.7e-10	-9.50	-9.0	1.6e-19	0.73	0.07	0.93	TRUE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	G6PC2	0.32	0.07	blup	29	0.06	3.8e-04	7.43	8.5	2.0e-17	-0.50	0.02	0.78	TRUE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SPC25	0.21	0.17	blup	17	0.19	5.2e-11	0.77	6.4	1.2e-10	-0.67	0.89	0.10	TRUE
4	GTEx	Esophagus Muscularis	NOSTRIN	0.18	0.00	enet	22	0.06	9.9e-05	-0.77	-6.4	1.3e-10	0.47	0.04	0.54	TRUE
8	GTEx	Stomach	NOSTRIN	0.15	0.04	enet	9	0.09	6.8e-05	-11.67	-11.8	6.1e-32	0.92	0.00	1.00	FALSE
9	GTEx	Testis	NOSTRIN	0.43	0.17	enet	17	0.32	1.0e-14	10.50	-11.6	3.6e-31	0.80	0.12	0.87	FALSE
10	METSIM	Adipose	NOSTRIN	0.07	0.09	lasso	6	0.08	1.6e-12	-11.67	-11.6	6.7e-31	1.00	0.00	1.00	FALSE
5	GTEx	Lung	NOSTRIN	0.09	0.06	lasso	4	0.07	7.1e-06	-11.73	-11.5	1.5e-30	0.93	0.00	1.00	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NOSTRIN	0.12	0.13	lasso	7	0.14	4.5e-15	9.15	-10.5	1.1e-25	0.79	0.31	0.69	FALSE
3	GTEx	Adrenal Gland	NOSTRIN	0.21	0.09	lasso	4	0.09	4.1e-04	-9.99	-10.4	1.6e-25	0.68	0.04	0.93	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	NOSTRIN	0.03	0.01	blup	55	0.02	9.5e-05	9.15	-10.3	6.9e-25	0.73	0.03	0.93	FALSE
23	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NOSTRIN	0.17	0.07	lasso	2	0.08	4.3e-04	-9.50	-10.3	7.8e-25	0.82	0.01	0.95	FALSE
6	GTEx	Pancreas	NOSTRIN	0.30	0.12	enet	17	0.08	3.3e-04	10.16	-10.0	2.0e-23	0.81	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	NOSTRIN	0.27	0.04	lasso	3	0.08	2.8e-03	-9.38	-9.4	3.6e-21	0.75	0.01	0.26	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	NOSTRIN	0.04	0.00	blup	55	0.01	1.6e-02	-9.38	-9.1	8.4e-20	0.65	0.06	0.79	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	NOSTRIN	0.06	0.01	blup	55	0.01	2.9e-02	8.26	-9.0	3.3e-19	0.72	0.15	0.62	FALSE
2	GTEx	Adipose Subcutaneous	NOSTRIN	0.11	0.03	lasso	4	0.04	1.6e-04	10.16	-8.5	2.5e-17	0.79	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	G6PC2	0.47	0.23	enet	8	0.28	4.4e-32	7.43	8.2	2.0e-16	-0.42	1.00	0.00	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	G6PC2	0.56	0.13	blup	29	0.16	2.1e-09	7.43	8.2	3.1e-16	-0.41	0.06	0.93	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	NOSTRIN	0.08	0.01	enet	6	0.04	2.1e-05	-9.73	-8.1	5.7e-16	0.70	0.04	0.90	FALSE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	G6PC2	0.22	0.01	enet	4	0.08	3.1e-06	7.43	6.7	1.6e-11	-0.33	0.07	0.58	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	NOSTRIN	0.08	0.01	blup	526	0.02	5.9e-04	2.76	-6.4	1.5e-10	0.47	0.41	0.48	FALSE
7	GTEx	Skin Sun Exposed Lower leg	NOSTRIN	0.14	0.04	enet	47	0.02	4.5e-03	-9.88	-5.9	3.3e-09	0.62	0.02	0.98	FALSE