[Hub]/) : Traits : Blood White Count : ← →

chr2:181,042,370-183,096,746

Best TWAS P=2.14e-38 · Best GWAS P=9.9e-57 conditioned to 3.21e-29

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Hippocampus FTH1P20 0.18 0.02 lasso 6 0.00 4.3e-01 8.4 -7.1 1.4e-12 0.00 0.08 0.06 TRUE
2 GTEx Esophagus Muscularis UBE2E3 0.10 0.09 lasso 3 0.08 2.2e-05 8.0 9.4 3.3e-21 -0.05 0.81 0.01 TRUE
3 GTEx Nerve Tibial UBE2E3 0.09 0.03 lasso 3 0.03 6.4e-03 6.9 7.4 1.1e-13 0.01 0.42 0.12 FALSE
4 METSIM Adipose ITGA4 0.04 0.00 bslmm 387 0.01 3.7e-02 -4.1 -9.7 3.9e-22 0.45 0.09 0.82 TRUE
5 NTR Blood ITGA4 0.03 0.01 bslmm 392 0.02 1.0e-06 -7.2 -13.0 2.1e-38 0.47 0.03 0.92 TRUE
6 NTR Blood UBE2E3 0.02 0.00 bslmm 446 0.00 1.1e-02 8.0 6.4 1.8e-10 -0.03 0.24 0.02 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma ITGA4 0.08 0.00 blup 90 0.04 1.5e-04 -13.7 -10.6 3.1e-26 0.56 0.02 0.25 TRUE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma UBE2E3 0.04 0.02 blup 61 0.02 1.4e-03 6.9 6.8 1.5e-11 -0.01 0.11 0.06 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma ITGA4 0.19 0.06 blup 90 0.09 1.8e-04 -7.2 -6.7 2.3e-11 0.56 0.07 0.45 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma ITGA4 0.04 0.03 lasso 4 0.04 7.5e-05 -5.4 -8.1 4.0e-16 0.43 0.31 0.26 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma UBE2E3 0.05 0.03 blup 61 0.03 4.0e-04 6.9 6.3 2.7e-10 0.04 0.48 0.04 TRUE
12 The Cancer Genome Atlas Thyroid Carcinoma ITGA4 0.04 0.03 blup 91 0.03 1.1e-03 4.3 8.6 5.4e-18 -0.31 0.22 0.17 TRUE