Best TWAS P=1.06e-08 · Best GWAS P=9.23e-07 conditioned to 0.0916
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | IKZF2 | 0.18 | 0.08 | enet | 21 | 0.10 | 8.9e-08 | 3.0 | 5.7 | 1.1e-08 | 0.63 | 0.11 | 0.79 | TRUE |
2 | GTEx | Thyroid | RP11-105N14.1 | 0.14 | 0.02 | lasso | 3 | 0.03 | 1.4e-03 | -4.8 | 5.2 | 2.1e-07 | 0.70 | 0.02 | 0.95 | FALSE |