Best TWAS P=2.38e-09 · Best GWAS P=6.87e-10 conditioned to 0.0121
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Female) | DNAJC13 | 0.11 | 0.00 | lasso | 2 | 0.02 | 0.0911 | 6.0 | -6.0 | 2.4e-09 | -0.76 | 0.04 | 0.20 | TRUE |
2 | GTEx | Esophagus Mucosa | DNAJC13 | 0.11 | 0.01 | enet | 27 | 0.03 | 0.0037 | 4.8 | -5.7 | 1.1e-08 | -0.50 | 0.11 | 0.75 | FALSE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | NPHP3 | 0.05 | 0.02 | blup | 43 | 0.03 | 0.0064 | 5.7 | -5.8 | 6.5e-09 | -0.46 | 0.01 | 0.76 | FALSE |