Best TWAS P=4.63e-09 · Best GWAS P=1.45e-10 conditioned to 0.0126
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | TRIT1 | 0.35 | 0.30 | enet | 6 | 0.28 | 8.4e-08 | 5.8 | 5.9 | 4.6e-09 | 0.67 | 0.06 | 0.92 | TRUE |
| 2 | GTEx | Esophagus Muscularis | MFSD2A | 0.10 | 0.02 | lasso | 5 | 0.04 | 2.7e-03 | 6.2 | 5.5 | 3.5e-08 | 0.52 | 0.04 | 0.78 | FALSE |
| 3 | GTEx | Testis | PPT1 | 0.22 | 0.14 | lasso | 5 | 0.20 | 3.6e-09 | 4.3 | 5.1 | 2.8e-07 | 0.15 | 0.90 | 0.07 | FALSE |
| 4 | YFS | Blood | CITED4 | 0.44 | 0.26 | lasso | 10 | 0.30 | 5.2e-99 | -5.7 | -5.5 | 5.1e-08 | 0.01 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PPT1 | 0.08 | 0.00 | blup | 57 | 0.04 | 1.7e-02 | 5.3 | 5.3 | 1.1e-07 | 0.13 | 0.02 | 0.51 | TRUE |