[Hub]/) : Traits : Blood White Count :

chr1:42,436,054-44,608,672

Best TWAS P=4.28e-15 · Best GWAS P=1.36e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TIE1 0.04 0.05 lasso 3 0.05 2.1e-06 5.2 -5.2 1.9e-07 0.05 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous TIE1 0.10 0.05 lasso 3 0.05 4.4e-05 5.2 -5.2 2.0e-07 0.05 0.98 0.00 FALSE
3 GTEx Adipose Subcutaneous SLC2A1-AS1 0.35 0.27 lasso 4 0.27 4.5e-22 -7.3 -7.0 3.7e-12 0.99 0.00 1.00 FALSE
4 GTEx Adrenal Gland SLC2A1-AS1 0.58 0.32 enet 29 0.29 5.1e-11 -7.3 -6.0 1.6e-09 0.86 0.00 1.00 FALSE
5 GTEx Artery Coronary SLC2A1-AS1 0.48 0.41 lasso 5 0.41 3.4e-15 -7.4 -7.2 7.2e-13 0.99 0.00 1.00 FALSE
6 GTEx Artery Tibial SLC2A1-AS1 0.51 0.25 lasso 7 0.37 5.4e-30 -7.3 -5.5 3.8e-08 0.89 0.00 1.00 FALSE
7 GTEx Brain Cerebellar Hemisphere SLC2A1-AS1 0.46 0.19 enet 18 0.24 6.3e-07 -7.3 -5.7 1.3e-08 0.82 0.00 0.99 FALSE
8 GTEx Brain Cerebellum SLC2A1-AS1 0.39 0.12 enet 14 0.23 1.6e-07 -2.1 -5.3 1.4e-07 0.69 0.04 0.94 FALSE
9 GTEx Breast Mammary Tissue TIE1 0.08 0.06 lasso 5 0.08 7.1e-05 5.3 -5.4 6.1e-08 0.05 0.71 0.01 FALSE
10 GTEx Breast Mammary Tissue SLC2A1-AS1 0.23 0.20 lasso 4 0.19 4.6e-10 -7.3 -7.6 3.6e-14 1.00 0.00 1.00 FALSE
11 GTEx Breast Mammary Tissue (Male) SLC2A1-AS1 0.23 0.21 lasso 7 0.16 1.6e-04 -7.4 -7.3 3.7e-13 0.95 0.00 0.97 FALSE
12 GTEx Cells Transformed fibroblasts RP1-92O14.6 0.12 0.02 lasso 5 0.03 3.6e-03 5.1 -5.2 1.7e-07 0.04 0.84 0.01 FALSE
13 GTEx Colon Sigmoid SLC2A1-AS1 0.56 0.28 lasso 8 0.38 2.9e-14 -2.1 -5.8 5.3e-09 0.86 0.01 0.99 FALSE
14 GTEx Colon Transverse SLC2A1-AS1 0.44 0.27 lasso 5 0.29 3.9e-14 -7.3 -6.1 1.2e-09 0.92 0.00 1.00 FALSE
15 GTEx Esophagus Gastroesophageal Junction SLC2A1-AS1 0.46 0.25 lasso 5 0.34 3.5e-13 -7.3 -5.4 5.7e-08 0.88 0.00 1.00 FALSE
16 GTEx Esophagus Mucosa LEPRE1 0.06 0.00 enet 24 0.00 5.5e-01 4.6 5.6 2.6e-08 -0.18 0.11 0.04 TRUE
17 GTEx Esophagus Mucosa SLC2A1-AS1 0.41 0.25 enet 20 0.24 1.7e-16 -7.3 -5.9 4.5e-09 0.93 0.00 1.00 FALSE
18 GTEx Esophagus Mucosa RP1-92O14.6 0.12 0.11 lasso 3 0.09 8.3e-07 5.2 -5.2 1.9e-07 0.05 0.99 0.00 FALSE
19 GTEx Heart Atrial Appendage SLC2A1-AS1 0.32 0.23 lasso 3 0.22 2.2e-10 -7.3 -7.0 1.9e-12 0.99 0.00 1.00 FALSE
20 GTEx Heart Left Ventricle SLC2A1-AS1 0.55 0.40 lasso 9 0.40 8.0e-23 -7.3 -7.2 5.5e-13 1.00 0.00 1.00 FALSE
21 GTEx Lung SLC2A1-AS1 0.19 0.17 lasso 4 0.17 5.1e-13 -7.4 -7.1 1.5e-12 0.98 0.00 1.00 FALSE
22 GTEx Muscle Skeletal TIE1 0.08 0.06 lasso 6 0.05 5.5e-06 5.1 -5.5 4.0e-08 0.05 0.99 0.00 FALSE
23 GTEx Muscle Skeletal MED8 0.23 0.37 lasso 1 0.37 7.7e-38 5.2 -5.2 1.7e-07 0.05 1.00 0.00 FALSE
24 GTEx Muscle Skeletal RP1-92O14.6 0.18 0.24 lasso 3 0.24 6.8e-23 5.2 -5.3 1.1e-07 0.05 1.00 0.00 FALSE
25 GTEx Nerve Tibial TIE1 0.20 0.09 lasso 6 0.13 2.6e-09 5.2 -5.6 1.9e-08 0.06 0.99 0.00 TRUE
26 GTEx Nerve Tibial MED8 0.13 0.07 enet 11 0.16 3.6e-11 4.8 5.3 1.3e-07 -0.04 1.00 0.00 FALSE
27 GTEx Nerve Tibial SLC2A1-AS1 0.61 0.43 lasso 12 0.44 9.7e-34 -7.3 -6.5 9.6e-11 0.98 0.00 1.00 FALSE
28 GTEx Prostate SLC2A1-AS1 0.36 0.20 enet 7 0.29 4.3e-08 -7.3 -5.9 4.1e-09 0.87 0.00 0.99 FALSE
29 GTEx Skin Not Sun Exposed Suprapubic SLC2A1-AS1 0.35 0.26 lasso 5 0.26 9.2e-15 -7.3 -6.9 4.3e-12 0.98 0.00 1.00 FALSE
30 GTEx Skin Sun Exposed Lower leg SLC2A1-AS1 0.43 0.39 lasso 5 0.41 4.6e-36 -7.3 -7.0 3.1e-12 0.99 0.00 1.00 FALSE
31 GTEx Skin Sun Exposed Lower leg RP1-92O14.6 0.13 0.07 lasso 5 0.07 1.6e-06 5.0 -5.2 1.9e-07 0.04 1.00 0.00 FALSE
32 GTEx Spleen SLC2A1-AS1 0.35 0.27 lasso 2 0.24 9.6e-07 -7.4 -7.4 1.7e-13 1.00 0.00 1.00 FALSE
33 GTEx Testis SZT2 0.14 0.12 lasso 3 0.09 5.7e-05 5.0 5.2 1.8e-07 -0.04 0.84 0.03 FALSE
34 GTEx Thyroid MED8 0.08 0.07 lasso 3 0.06 2.0e-05 5.2 5.3 1.4e-07 -0.05 0.96 0.00 FALSE
35 GTEx Uterus RP5-994D16.9 0.37 0.20 lasso 6 0.14 7.5e-04 4.6 -5.1 2.9e-07 0.22 0.23 0.08 FALSE
36 GTEx Whole Blood SLC2A1-AS1 0.22 0.14 lasso 2 0.14 1.3e-12 -7.3 -6.9 5.6e-12 0.99 0.00 1.00 FALSE
37 METSIM Adipose SLC2A1 0.07 0.05 lasso 10 0.04 2.3e-06 -7.4 -7.8 4.3e-15 0.99 0.00 1.00 TRUE
38 METSIM Adipose SLC2A1-AS1 0.36 0.24 lasso 8 0.24 1.3e-35 -7.4 -7.1 1.0e-12 0.99 0.00 1.00 FALSE
39 YFS Blood PPIH 0.01 0.01 lasso 2 0.01 6.8e-05 -5.0 -5.5 2.9e-08 0.23 0.72 0.01 FALSE
40 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ELOVL1 0.06 0.04 blup 36 0.03 4.7e-03 5.2 -5.4 5.5e-08 0.05 0.02 0.92 FALSE
41 The Cancer Genome Atlas Brain Lower Grade Glioma C1orf84 0.01 0.02 blup 45 0.02 3.0e-03 4.9 -5.2 1.5e-07 0.04 0.03 0.75 FALSE
42 The Cancer Genome Atlas Lung Adenocarcinoma C1orf84 0.02 0.02 blup 45 0.02 1.3e-03 5.2 -5.5 4.0e-08 0.05 0.02 0.87 FALSE
43 The Cancer Genome Atlas Lung Adenocarcinoma CDC20 0.03 0.03 blup 34 0.03 8.8e-05 5.1 -5.5 3.7e-08 0.07 0.02 0.95 FALSE
44 The Cancer Genome Atlas Lung Adenocarcinoma MED8 0.02 0.02 blup 39 0.01 7.5e-03 5.0 -5.6 2.5e-08 0.06 0.01 0.68 FALSE