Hub : Genes

TBC1D14

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1608	0.0475	4.3e-04	0.073	NA	0.060	NA	0.080	2.3e-06	NA	1.8e-05	NA	7.8e-07
2	GTEx	Brain Caudate basal ganglia	0.3900	0.1160	4.4e-03	0.014	NA	-0.003	NA	-0.010	1.3e-01	NA	4.0e-01	NA	8.4e-01
3	GTEx	Brain Frontal Cortex BA9	0.4113	0.1283	6.3e-03	-0.010	NA	0.002	NA	-0.005	7.9e-01	NA	2.9e-01	NA	4.5e-01
4	GTEx	Esophagus Mucosa	0.2550	0.0500	7.5e-08	0.215	NA	0.197	NA	0.237	2.0e-14	NA	3.3e-13	NA	6.9e-16
5	GTEx	Skin Sun Exposed Lower leg	0.1080	0.0430	7.7e-03	0.079	NA	0.065	NA	0.072	4.2e-07	NA	4.2e-06	NA	1.5e-06
6	GTEx	Stomach	0.2540	0.0830	6.5e-03	0.011	NA	0.011	NA	0.035	9.6e-02	NA	9.0e-02	NA	8.8e-03
7	NTR	Blood	0.0537	0.0132	9.6e-07	0.026	0.020	0.022	0.021	0.022	4.8e-09	2.4e-07	9.5e-08	1.4e-07	7.5e-08
8	YFS	Blood	0.1965	0.0264	0.0e+00	0.182	0.137	0.177	0.191	0.182	2.3e-57	1.7e-42	1.6e-55	2.6e-60	3.5e-57
9	TCGA	Thyroid Carcinoma	0.0640	0.0350	3.9e-04	0.040	0.040	0.044	NA	0.052	8.2e-05	8.5e-05	4.0e-05	NA	7.6e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.8	1.9	-1.1	-0.2	0.3	-1.0	-1.2	0.6	0.8	0.0	1.4
Bipolar Disorder or Schizophrenia	0.5	1.1	5.1	-0.5	-0.4	0.4	0.1	-0.6	1.6	1.2	0.6	2.3
Depressed Affect (Nagel 2018)	1.4	2.9	6.4	-1.9	-0.3	-1.0	-2.1	-2.5	0.8	2.1	1.4	1.9
Depression (Nagel 2018)	0.8	1.1	3.3	-0.8	0.5	0.3	-0.2	-1.0	0.7	1.8	1.6	1.4
Intelligence (Savage-Jansen 2018)	0.4	1.4	3.4	0.3	1.8	0.3	1.6	1.5	-1.8	-0.3	-0.2	-0.8
Neuroticism (Nagel 2018)	0.7	1.7	2.7	-0.4	-1.0	-1.6	-1.4	-1.1	1.4	1.4	1.2	1.7
Schizophrenia (2018)	0.4	0.9	3.2	0.3	-0.3	0.2	0.9	0.2	1.5	0.9	0.7	1.8
Schizophrenia vs Biploar Disorder	0.3	0.4	1.7	0.4	-1.3	-0.2	0.3	0.0	-0.6	0.6	0.9	0.2
Worry (Nagel 2018)	0.3	0.7	2.3	0.4	-1.4	-0.5	-0.2	0.1	1.5	0.6	0.4	0.9
Alzheimer’s Disease (in mother)	1.8	2.1	7.5	2.7	-0.1	-1.2	1.1	2.3	0.3	-1.1	-0.3	-1.3
Alzheimer’s Disease (in father)	0.8	0.9	1.9	-1.4	-0.4	1.2	0.7	-0.5	-0.0	1.2	1.3	0.5
Alzheimer’s Disease (including proxy)	1.4	2.0	5.3	2.2	-0.3	-0.4	2.0	2.3	0.8	-0.6	0.5	-1.4
Crohns Disease (2017)	1.7	3.6	10.9	0.5	-3.3	-2.9	-2.3	-1.3	-0.2	-1.4	-2.1	0.0
Irritable Bowel Disease (IBD)	1.4	3.4	6.7	0.1	-2.6	-2.3	-2.4	-1.5	-0.5	-2.1	-2.4	-0.7
Ulcerative Colitis (UC)	0.6	1.1	3.4	0.2	-0.7	-0.5	-1.1	-0.6	-0.4	-1.8	-1.7	-1.0
Major Depression (MDD)	1.4	1.7	8.9	-1.1	0.0	1.8	-0.3	-0.3	-3.0	-0.4	-0.5	-1.1
Reaction Time	0.4	0.7	3.4	-0.1	1.8	-0.1	0.9	0.3	1.3	0.4	0.6	0.4
Verbal and Numeric Reasoning (VNR)	0.6	1.5	3.9	0.8	0.5	2.0	1.7	1.6	-1.5	-0.4	-0.0	-1.0
Breast Cancer	0.4	1.0	4.1	0.4	2.0	1.1	-0.4	0.0	-0.1	-0.7	-1.4	-0.7
Ovarian Cancer	0.8	1.0	3.6	0.6	0.7	-0.1	0.6	0.2	1.9	1.4	0.9	1.1
Prostate Cancer	1.1	1.5	7.2	1.2	-2.7	-1.1	0.5	0.8	-0.1	-1.0	-0.5	-1.4
Age at First Birth	2.8	4.1	22.0	-2.4	-0.8	2.0	0.6	-0.5	-4.7	1.3	0.6	1.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.3	0.4	1.2	0.6	0.3	-0.4	-0.4	0.2	-1.1	-0.7	-1.0	-0.3
Coronary Artery Disease (CAD)	1.3	1.6	4.6	0.1	-0.2	1.1	-1.5	-0.8	-0.7	-1.8	-2.1	-1.2
Crohns Disease (2012)	2.5	4.1	13.5	0.0	-2.0	-3.7	-2.9	-1.7	0.8	-1.5	-2.2	0.3
Mean Putamen Volume	0.3	0.4	0.9	-0.5	0.9	0.9	0.6	0.4	-0.6	-0.0	-0.3	-0.9
Fasting Glucose	2.7	3.2	6.1	2.0	-1.6	-0.8	1.6	2.5	-1.3	-2.0	-1.0	-2.5
HbA1C	2.3	2.5	4.8	-2.0	-0.5	1.2	-1.1	-2.1	-1.3	1.9	1.1	2.2
HDL Cholesterol	0.2	0.3	1.0	0.3	-0.1	-1.0	-0.5	-0.2	0.4	-0.5	-0.8	0.1
LDL Cholesterol	2.1	3.4	7.6	-2.5	-0.0	0.6	-2.4	-2.8	-2.2	1.5	1.0	1.6
Lupus	0.5	0.7	2.8	1.7	0.8	-0.3	-0.3	0.3	0.7	0.7	0.5	1.2
Neuroticism (2016)	0.1	0.1	0.6	0.3	-0.2	-0.8	-0.2	-0.4	0.2	-0.1	0.2	-0.2
Primary Biliary Cirrhosis	0.7	1.0	2.9	0.1	-1.3	-1.4	0.9	0.9	-1.7	0.0	0.2	-0.7
Rheumatoid Arthritis	1.6	2.2	5.5	2.4	-1.6	1.6	0.8	2.0	-0.7	-1.4	-0.7	-1.1
Schizophrenia (2014)	0.2	0.4	2.2	-0.4	-0.1	0.1	0.5	-0.4	0.8	0.5	0.0	1.5
Triglycerides	0.2	0.3	1.3	-0.4	-0.6	0.8	0.5	0.3	-1.1	-0.1	-0.2	-0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.2	0.4	-0.1	0.2	0.4	0.6	-0.1	-1.2	-1.5	-1.5
Ulcerative Colitis	1.4	2.0	5.5	0.4	-0.7	-0.9	-1.9	-0.8	0.5	-2.2	-2.3	-1.5
Blood Eosinophil Count	0.3	2.6	7.6	1.2	0.4	1.1	2.8	2.2	-0.1	-1.4	-1.0	-2.2
Blood Platelet Count	0.9	10.8	38.8	-2.6	-0.6	-2.8	-2.6	-3.9	2.8	3.3	1.7	6.2
Blood Red Count	0.4	3.8	11.7	1.7	-1.3	-0.6	2.1	2.4	-0.3	-2.3	-1.3	-3.4
Blood White Count	2.4	18.1	52.6	-2.7	-0.8	0.1	0.2	-2.6	1.9	7.2	6.7	6.9
Heel T-Score	0.6	4.5	12.1	2.0	-0.4	0.9	1.3	2.0	-0.5	-3.0	-3.5	-2.8
BMI	0.6	3.7	10.0	0.9	-2.4	0.5	3.2	2.7	-1.6	-1.4	-0.5	-2.0
Height	0.8	15.1	34.7	-3.4	-1.2	-1.7	-3.7	-5.2	0.9	5.4	3.8	5.9
Waist Hip Ratio (WHR)	1.3	5.7	17.0	2.4	-0.4	-0.1	0.6	2.0	-0.8	-3.8	-2.9	-4.1
Systolic Blood Pressure	0.5	2.7	5.8	1.3	-1.1	1.7	1.1	1.5	-1.5	-1.8	-2.0	-2.4
Smoking Status	0.2	0.4	1.3	-0.7	-0.6	0.3	-0.2	-0.7	0.6	-0.5	-0.7	-1.1
Allergy or Eczema	0.6	1.5	7.5	1.0	-1.6	-2.7	0.5	0.7	1.1	-0.1	0.2	-0.5
Cardiovascular Disease	0.5	1.5	3.3	0.1	-1.0	-0.3	1.3	1.0	-1.1	-1.8	-1.4	-1.8
Hypothyroidism (self reported)	0.4	1.0	2.3	-1.5	-0.6	0.5	-1.5	-1.4	-1.0	-0.5	-0.5	-0.1
Respiratory disease	0.5	1.0	2.4	-1.3	-1.1	-0.3	0.8	-0.6	-0.3	1.6	1.3	1.2
Type 2 Diabetes (T2D) (2018)	0.6	1.2	3.0	-0.1	-1.7	-0.9	0.8	0.3	-0.3	-1.3	-1.3	-1.7
Lung FEV1/FVC ratio	0.1	0.4	1.0	-0.3	-1.0	-0.6	0.7	0.4	-0.9	0.1	0.9	-0.2
Lung FVC	0.5	2.4	6.7	2.6	0.3	0.2	0.6	2.0	-0.3	-2.0	-1.3	-2.2
Neuroticism	0.7	1.7	4.4	-1.5	-1.4	-0.8	-2.1	-2.1	-0.3	0.9	0.4	0.8
Chronotype (morning person)	0.3	0.7	1.6	0.6	-1.1	0.5	0.6	0.7	0.1	-1.2	-1.1	-0.6
Hair Pigment	0.1	1.6	4.5	0.7	-0.5	-1.3	-0.2	0.6	-2.1	-1.4	-1.1	-1.9
Tanning	0.0	0.4	0.7	0.1	0.8	0.7	-0.7	-0.5	0.7	0.5	0.8	0.6
Hand grip strength (left)	0.3	0.8	1.7	1.3	1.0	0.7	1.2	1.3	0.8	-0.0	-0.3	-0.0
Number of treatments/medications taken	0.3	0.5	1.6	-0.8	-0.3	0.3	0.9	-0.1	-0.7	0.9	1.3	-0.3
Average weekly spirits intake	0.4	0.5	1.5	-0.5	1.2	0.0	0.2	0.0	-0.3	-0.7	-0.7	-1.2
Sensitivity / hurt feelings	0.3	0.4	1.9	-0.3	-0.6	-0.6	-1.4	-1.0	0.0	-0.4	-0.5	-0.0
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.8	-0.8	0.2	0.1	-0.6	-0.8	0.4	-0.5	-0.9	-0.1
Hearing difficulty/problems: Yes	1.1	1.7	4.6	0.1	-0.2	-0.2	2.1	1.3	1.2	1.6	2.1	0.9
Relative age of first facial hair	1.1	2.2	5.4	-1.4	0.8	1.8	-0.6	-1.2	0.7	1.9	1.8	2.3
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.2	1.1	-0.7	-0.8	-0.2	0.5	0.0	0.1	0.5	-0.2
Ever used hormone-replacement therapy (HRT)	0.7	0.9	4.6	-0.3	1.4	2.2	-0.1	-0.1	-0.3	0.7	0.5	0.6
Ever had hysterectomy (womb removed)	0.4	0.5	1.0	-0.4	-0.2	1.0	-0.7	-0.6	0.7	1.0	0.5	0.8
Systolic blood pressure, automated reading	0.4	1.1	2.4	1.6	0.4	0.9	1.2	1.5	0.4	-0.7	-0.6	-1.6
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.2	-0.1	-1.5	0.8	0.7	-0.1	0.4	-0.4	-0.7	-0.2
Angina	1.0	1.3	3.4	-0.2	1.4	-0.4	0.6	0.4	1.0	-1.8	-1.8	-1.3
Medication for hormone replacement therapy	0.6	0.7	2.0	0.8	-0.9	1.1	0.1	0.4	-1.1	0.0	0.1	-1.4
Vitamin and mineral supplements	1.6	2.2	6.5	-1.8	-0.1	0.1	-2.5	-2.6	-0.1	0.4	-0.5	1.7
Supplements: Zinc	0.4	0.5	1.8	0.7	0.3	0.0	-0.5	-0.3	0.7	1.0	1.4	0.0
Medication: Co-codamol	1.4	1.6	4.1	1.7	-0.6	1.3	1.7	2.0	0.5	-0.8	-0.7	-1.1
Medication: Metformin	0.8	1.1	3.8	-0.4	-2.0	-0.5	0.3	-0.1	-1.4	-1.3	-1.0	-1.0
Diabetes (father)	2.2	2.7	10.4	1.8	-0.3	1.2	3.2	2.8	-0.1	-0.3	0.6	-0.6
Diabetes (mother)	0.5	0.7	1.8	-0.9	-1.3	1.3	-0.0	-0.3	-0.9	-0.6	-0.0	-0.9
Severe depression (siblings)	0.8	0.9	2.7	-1.1	0.8	0.7	-0.2	-0.8	0.2	1.5	0.7	1.6
Pack years adult smoking proportion	0.4	0.5	2.2	0.1	1.1	0.6	0.0	-0.4	1.5	0.5	0.7	0.5
Impedance of leg (right)	0.1	0.5	1.6	1.0	0.5	-0.3	-1.3	-0.4	0.6	0.3	0.0	0.9
Leg fat-free mass (left)	0.3	1.4	3.8	-1.9	-1.6	0.1	0.4	-1.1	-0.7	1.4	1.4	0.9
Trunk fat percentage	0.3	1.3	5.8	0.2	-2.4	1.0	1.1	0.8	-1.4	0.5	0.9	0.1
Hand grip strength (right)	0.3	0.8	2.2	1.5	0.4	-0.5	1.0	1.2	1.4	0.3	-0.3	0.3
Townsend deprivation index at recruitment	1.3	1.9	3.9	0.5	-0.9	-0.7	1.4	1.3	-2.0	-1.8	-1.3	-1.6
Current tobacco smoking	0.2	0.3	1.6	-0.3	-0.1	0.2	-0.6	-0.6	1.3	0.5	0.4	0.4
Average weekly fortified wine intake	0.8	0.9	3.3	-1.3	0.2	1.8	0.2	-0.6	-0.2	1.1	1.0	0.8
Maternal smoking around birth	0.1	0.2	0.5	-0.6	-0.7	-0.0	-0.3	-0.3	-0.5	0.3	0.3	0.2
Fed-up feelings	0.3	0.5	1.5	-0.8	-0.5	-0.6	-1.1	-1.2	0.0	0.5	0.2	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.6	-0.4	0.6	0.1	-1.6	-1.4	0.7	0.7	0.2	0.9
Relative age voice broke	0.4	0.5	2.0	-0.6	0.1	1.2	0.1	-0.2	0.0	0.7	1.4	0.7
Taking other prescription medications	1.0	1.5	4.4	1.0	-0.6	-0.9	2.1	1.5	0.8	-0.8	-0.4	-1.7
Age when periods started (menarche)	0.9	2.0	4.1	-0.9	0.1	1.7	-1.9	-2.0	-0.2	1.8	0.9	1.7
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	2.6	-0.9	0.2	0.7	-0.7	-1.2	0.3	1.6	1.4	1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	9.4	-0.4	0.0	3.1	1.7	1.3	-1.8	-1.1	-1.5	-1.5
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.5	0.5	0.2	0.7	-0.2	0.1	-0.1	-0.2	0.0	-0.2
Qualifications: CSEs or equivalent	0.8	1.0	2.8	-0.6	-1.7	-0.0	-1.4	-1.3	0.0	-0.3	-1.6	0.2
Serious illness, injury or assault to yourself	0.4	0.5	1.4	-0.3	1.2	-0.5	-0.7	-0.8	1.0	-0.4	-0.4	-0.3
High blood pressure	0.2	0.7	2.7	0.6	-1.6	-0.4	0.4	0.6	0.7	-1.0	-0.6	-0.6
Hayfever, allergic rhinitis or eczema	0.7	1.4	7.2	0.6	-2.0	-2.7	-0.1	0.2	1.1	-0.0	0.1	-0.1
Multivitamins +/- minerals	1.3	1.7	5.7	1.0	0.3	1.0	2.4	2.1	-0.8	0.2	1.1	-1.1
Stomach or abdominal pain in last month	1.5	1.9	4.2	0.7	-1.2	0.5	1.8	2.0	-1.7	-1.3	-0.7	-1.6
Supplements: Glucosamine	1.3	1.6	4.6	2.1	1.3	-0.9	0.5	1.3	1.5	-1.0	-0.4	-1.5
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.9	0.9	-0.0	0.3	0.2	0.5	0.8	0.6	0.6	0.0
Medication: Atenolol	0.1	0.1	0.2	-0.2	-0.3	-0.4	-0.4	-0.0	-0.2	-0.3	-0.0	0.3
Medication: Levothyroxine sodium	0.9	1.5	4.0	-0.1	0.9	0.6	-0.6	0.1	-1.3	-2.0	-1.7	-1.9
Sitting height	1.3	9.0	23.7	-3.3	0.3	-1.2	-1.6	-3.6	0.5	4.4	3.1	4.9
Chronic bronchitis/emphysema (father)	1.2	1.4	4.8	-0.4	-0.4	-0.4	-0.1	0.0	-0.9	2.0	2.2	1.5
High blood pressure (mother)	0.7	0.9	2.8	-1.1	-1.7	0.7	-0.2	-0.7	-1.3	-0.6	-0.5	-1.1
Body mass index (BMI)	0.7	2.9	5.7	0.5	-2.2	1.1	1.9	1.8	-1.5	-1.8	-1.2	-2.4
Impedance of leg (left)	0.1	0.4	1.7	1.3	0.2	-0.2	-0.8	0.0	0.3	0.2	-0.1	0.8
Leg predicted mass (left)	0.3	1.4	3.8	-2.0	-1.6	0.1	0.3	-1.1	-0.8	1.3	1.2	0.8
Trunk fat mass	0.4	1.5	7.1	-0.5	-2.7	0.8	0.8	0.2	-1.5	0.9	1.2	0.5
Waist circumference	0.5	1.7	6.1	-0.0	-2.5	0.5	0.7	0.7	-1.5	-1.4	-1.0	-1.6
Number of incorrect matches in round	0.5	0.8	4.8	0.5	-0.5	2.2	0.4	0.7	-0.9	0.2	0.2	-0.1
Past tobacco smoking	0.2	0.3	0.8	0.7	-0.5	-0.3	0.1	0.6	-0.4	0.5	0.3	0.9
Alcohol usually taken with meals	1.3	2.1	6.8	1.7	0.2	0.0	2.6	2.6	-0.4	-0.3	0.9	-1.2
Nervous feelings	0.3	0.6	2.4	0.8	-1.6	-0.5	0.2	0.3	1.0	0.4	0.4	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.4	-1.2	-0.1	-1.2	-0.5	-0.9	-0.2	-0.2	-0.3	0.2
Hearing difficulty/problems with background noise	1.5	2.4	7.1	-1.1	0.3	1.1	1.7	0.7	0.2	2.4	2.7	1.6
Hair/balding pattern: Pattern 2	0.7	0.9	2.9	1.4	-0.4	0.8	1.4	1.7	-0.1	-0.6	-0.3	-0.5
Had menopause	0.1	0.1	0.5	0.1	0.7	-0.6	-0.1	0.3	0.1	0.1	0.2	0.3
Had other major operations	0.6	0.7	1.3	-1.0	-0.8	0.2	0.7	-0.3	-1.0	1.1	1.1	0.6
Forced vital capacity (FVC)	0.2	0.6	3.1	1.8	-0.1	-0.9	-0.2	0.6	0.5	-0.5	-0.5	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	3.3	-0.3	0.8	1.8	1.3	1.0	-0.5	-0.7	-0.8	-0.6
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	4.9	-1.1	1.4	-2.1	-1.9	-2.1	2.2	0.8	0.1	1.4
Qualifications: None of the above	1.0	2.2	7.0	-0.3	-2.6	-2.6	-1.7	-1.2	0.4	-0.7	-0.9	0.0
Financial difficulties in last 2 years	0.1	0.2	0.5	0.7	-0.3	0.1	0.4	0.6	0.4	-0.3	0.3	-0.2
Mouth/teeth dental problems	1.5	2.3	4.8	-2.2	0.1	-0.9	-1.6	-2.0	-1.0	1.6	1.2	1.8
Heart attack	0.5	0.7	2.2	-0.9	-0.8	-1.5	-0.8	-1.3	0.3	0.1	-0.1	0.3
Allergy	0.4	0.9	2.8	0.1	1.1	1.7	-0.5	-0.1	-0.8	-1.1	-1.4	-0.7
Pain all over the body in last month	0.2	0.2	0.8	-0.4	-0.9	0.5	-0.5	-0.4	-0.2	0.3	0.2	0.2
Diabetes (self-reported)	0.8	1.2	2.7	-0.4	-1.5	-0.4	1.0	0.5	-0.3	-1.5	-1.3	-1.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.0	0.9	0.4	-0.3	0.9	0.7	0.9	-0.9	-0.9	-1.4
Medication: Ramipril	0.2	0.3	0.9	0.0	0.0	-0.3	-0.5	-0.4	-0.1	-0.9	-0.8	-0.8
Medication: Simvastatin	0.5	0.7	2.7	0.1	-0.6	-0.5	0.3	0.5	-1.0	-1.6	-1.0	-1.0
Fluid intelligence score	0.7	1.5	3.5	1.0	0.8	1.0	1.4	1.5	-1.9	-1.1	-1.0	-1.2
Illnesses of siblings	0.3	0.4	0.9	0.9	0.0	0.3	0.9	0.9	-0.0	-0.6	-0.9	-0.5
Neuroticism score	0.7	1.4	3.4	-1.6	-1.2	-1.1	-1.7	-1.8	-0.4	0.6	0.2	0.6
Weight	0.2	1.1	5.5	-1.1	-2.4	0.4	0.3	-0.5	-1.2	0.6	0.6	0.3
Impedance of arm (right)	0.3	1.6	4.7	0.8	1.1	0.9	-1.8	-0.9	0.6	1.3	0.9	2.2
Arm fat percentage (right)	0.6	2.5	5.2	1.0	-2.3	1.7	1.5	1.8	-1.4	-1.4	-0.9	-1.7
Trunk fat-free mass	0.3	1.7	5.1	-2.2	-1.4	-0.4	-0.5	-1.8	-0.5	1.4	1.1	1.1
Hip circumference	0.3	1.1	4.7	-1.4	-2.2	0.7	0.2	-0.6	-1.1	0.7	0.4	0.8
Time employed in main current job	1.0	1.2	4.2	-0.6	2.0	1.5	1.3	0.7	0.3	0.9	0.7	0.5
Alcohol intake versus 10 years previously	0.9	1.3	2.3	-0.6	-0.4	-1.3	-1.3	-1.3	-0.0	1.5	1.5	1.4
Father’s age at death	0.7	0.9	3.3	0.1	1.2	1.8	0.4	0.6	-1.5	0.3	0.0	0.5
Worrier / anxious feelings	0.3	0.6	2.0	-0.9	-1.1	-0.2	-0.6	-0.4	-0.4	0.7	0.3	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	0.7	-0.4	0.1	0.5	0.6	-0.3	-0.4	0.0	-0.5
Falls in the last year	0.2	0.3	1.3	-0.6	0.1	0.6	-0.5	-0.3	-1.2	-0.2	-0.2	-0.0
Hair/balding pattern: Pattern 3	0.7	1.0	2.4	-0.8	0.5	-0.4	-0.3	-1.0	1.5	1.1	1.4	1.3
Number of live births	3.1	4.4	8.7	1.6	-1.4	0.1	2.3	2.5	-1.1	-3.0	-2.3	-2.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	2.0	1.4	-0.1	-0.9	0.2	0.9	0.0	-0.6	-0.4	-0.7
Pulse rate	0.4	0.6	2.6	1.0	-1.6	0.6	-0.6	0.0	0.4	-0.6	-0.6	-0.5
Happiness	0.4	0.4	1.8	0.5	0.3	-1.0	0.4	0.2	1.3	0.5	0.3	0.4
Noisy workplace	0.2	0.3	1.9	-0.1	0.5	-1.4	-0.3	-0.3	-0.0	-0.0	0.2	0.2
Qualifications: A levels/AS levels or equivalent	0.3	0.7	4.1	0.3	2.0	1.0	0.3	0.3	-0.2	-0.4	-0.4	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	1.0	0.5	-0.3	-1.0	-0.2	0.1	-0.9	0.2	0.2	0.4
Mouth/teeth dental problems: Dentures	0.6	1.0	3.5	1.9	0.1	0.3	0.8	1.4	1.4	-0.6	0.2	-0.8
Asthma	0.8	1.5	3.4	-1.4	-0.8	0.0	-0.1	-1.1	0.7	1.8	1.7	1.8
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	5.7	-1.6	-0.1	1.5	-0.4	-1.4	-0.3	2.4	2.0	1.3
Medication: Cholesterol lowering	0.6	0.9	2.1	-1.5	-0.8	-1.0	-0.5	-0.8	-1.5	-0.8	-0.7	-0.5
Depression (self-reported)	1.2	1.5	2.8	-0.9	-1.3	-1.6	-1.5	-1.7	-0.5	1.1	0.4	1.3
Medication: Lansoprazole	0.4	0.5	2.0	0.5	0.3	0.2	0.3	0.9	-1.4	0.4	0.9	-0.3
Prospective memory result	0.7	0.9	2.6	-0.4	1.3	-0.4	-0.5	-0.5	0.8	1.0	1.1	1.6
Lung cancer (father)	0.3	0.3	1.2	0.5	-1.1	-0.7	-0.1	0.3	0.4	-0.1	0.5	0.7
Illnesses of mother	1.7	2.1	6.9	-0.1	2.6	-0.5	-0.6	-0.8	1.6	1.7	1.2	1.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.9	1.4	0.5	0.2	0.8	1.2	-0.6	0.0	0.5	-0.1
Pulse wave Arterial Stiffness index	0.4	0.5	1.2	0.3	0.4	-1.1	0.8	0.5	-1.0	-0.4	-0.0	-0.9
Impedance of arm (left)	0.3	1.3	4.0	0.6	1.3	0.1	-1.5	-0.7	0.4	1.3	0.8	2.0
Arm fat mass (right)	0.4	1.7	4.6	0.3	-2.2	1.5	1.5	1.3	-1.4	-0.9	-0.5	-1.3
Trunk predicted mass	0.3	1.5	4.5	-2.1	-1.4	-0.3	-0.4	-1.7	-0.4	1.3	1.1	1.0
Standing height	1.2	12.1	29.8	-3.1	-0.4	-1.5	-2.9	-4.4	0.7	5.0	3.8	5.5
Length of working week for main job	0.6	0.6	2.3	-1.1	1.5	0.0	0.0	-0.7	-0.8	-0.8	-0.8	-0.4
Exposure to tobacco smoke at home	0.8	0.9	2.5	-1.0	0.7	1.6	0.8	-0.4	-0.4	1.2	1.2	0.7
Breastfed as a baby	0.2	0.2	0.6	-0.8	-0.0	-0.2	0.3	0.2	0.3	0.7	0.7	0.3
Tense / ‘highly strung’	0.4	0.6	3.3	0.2	-1.1	-0.5	0.1	0.1	1.8	0.6	0.4	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	4.7	-2.2	1.0	-0.8	-0.7	-1.7	-0.2	1.7	1.1	1.4
Hair/balding pattern: Pattern 4	0.3	0.8	1.4	-0.6	-0.8	-1.2	-0.8	-0.9	-0.6	1.2	1.1	0.8
Birth weight of first child	1.2	2.2	10.1	0.3	-0.4	-0.8	-1.9	-1.3	3.2	1.1	0.4	1.4
Peak expiratory flow (PEF)	0.2	0.5	1.7	-0.2	0.3	-0.1	1.2	1.1	-1.3	-0.3	-0.1	-0.4
Pulse wave reflection index	0.9	1.1	2.7	0.5	1.0	-1.6	1.0	1.1	-1.5	-0.6	-0.1	-1.1
Ever highly irritable/argumentative for 2 days	0.9	1.0	6.3	1.4	0.6	-0.1	-0.2	0.4	2.5	-0.3	0.2	0.5
Loud music exposure frequency	0.2	0.2	0.5	-0.6	-0.4	-0.5	0.1	-0.3	0.1	0.3	0.5	0.7
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	4.7	1.4	1.6	2.2	1.8	2.0	0.4	-0.3	0.3	-0.7
Mouth/teeth dental problems: Bleeding gums	2.7	3.4	7.8	2.1	-1.1	1.0	1.4	2.2	-0.1	-2.4	-2.1	-2.8
Blood clot in the leg (DVT)	0.8	1.1	2.2	1.1	0.3	-1.2	1.4	1.5	0.3	0.7	1.5	-0.3
Medication: Paracetamol	1.1	1.8	6.2	-0.5	0.0	1.3	1.4	0.7	-1.1	2.0	2.5	0.5
Headache pain in last month	0.2	0.4	1.9	-0.9	-0.1	1.4	-0.0	-0.6	-0.6	0.3	0.3	-0.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.3	1.1	1.0	-0.1	0.6	0.9	1.5	0.1	-0.2	0.2
Glaucoma (self-reported)	0.4	0.5	2.0	-0.2	1.4	-1.3	-0.2	-0.2	0.0	-0.1	0.0	-0.6
Gout (self-reported)	0.9	1.2	2.9	-1.6	-0.5	1.2	-0.0	-0.6	-1.7	-0.7	-1.6	-0.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	2.0	-1.0	0.2	-0.3	-1.3	-1.0	-1.1	-1.4	-1.3	-1.3
Medication: Amlodipine	0.5	0.7	1.7	-1.3	-0.0	-1.1	-1.1	-1.3	-0.3	-0.6	-0.3	0.2
Medication: Ventolin 100micrograms inhaler	0.5	0.6	4.6	0.2	0.2	-0.6	-0.3	-0.5	2.1	0.0	0.1	0.7
Birth weight	0.9	2.0	6.7	-0.8	-1.5	-0.3	-0.8	-1.5	0.6	2.0	1.1	2.6
Chronic bronchitis/emphysema (mother)	0.8	0.9	3.5	-0.9	-1.9	-0.2	-0.7	-1.0	-1.2	0.2	0.3	0.6
High blood pressure (siblings)	0.1	0.2	0.4	-0.3	-0.7	-0.4	-0.7	-0.6	0.3	0.1	0.1	0.0
Forced vital capacity (FVC), Best measure	0.1	0.5	2.2	1.5	0.8	0.2	0.5	0.9	0.1	0.4	0.8	0.1
Body fat percentage	0.4	1.6	7.2	0.3	-2.7	1.2	1.3	1.0	-1.7	-0.0	0.4	-0.5
Leg fat percentage (right)	0.5	1.8	6.9	0.6	-2.6	0.9	1.2	1.3	-1.3	-1.0	-0.6	-1.5
Arm fat-free mass (right)	0.2	1.3	3.7	-1.9	-1.8	-0.6	0.4	-1.1	-0.6	1.1	0.9	0.5
Exposure to tobacco smoke outside home	0.1	0.1	0.5	0.1	-0.1	-0.7	0.0	-0.1	-0.4	-0.6	-0.6	-0.1
Comparative body size at age 10	0.1	0.4	1.3	0.5	0.0	-1.1	1.0	0.7	-0.2	0.1	0.4	0.3
Number of full brothers	1.4	1.7	5.2	-0.5	1.0	1.9	-0.3	-0.0	0.0	-1.8	-2.3	-1.4
Worry too long after embarrassment	0.2	0.3	0.7	-0.3	0.2	-0.7	-0.7	-0.4	-0.1	-0.8	-0.9	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	3.0	-0.6	1.2	-1.7	0.5	-0.3	0.7	1.1	0.7	0.9
Wheeze or whistling in the chest in last year	0.5	0.9	4.7	0.0	0.1	1.0	2.2	0.9	-0.3	0.8	1.0	-0.2
Number of children fathered	0.1	0.1	0.1	-0.3	-0.4	0.2	0.1	-0.2	0.3	0.2	-0.3	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	1.9	2.2	6.5	2.3	0.5	-0.3	2.2	2.5	1.0	-0.4	0.3	-1.2
Age at first live birth	0.3	0.6	2.5	0.2	0.6	1.6	0.7	0.2	-0.5	0.9	0.8	0.4
Pulse wave peak to peak time	0.7	0.8	2.0	-0.6	-0.4	1.0	-0.9	-0.8	1.2	1.0	0.5	1.4
Health satisfaction	0.4	0.6	1.5	0.6	1.2	0.4	0.6	0.7	0.2	-0.9	-0.7	-1.0
Shortness of breath walking on level ground	0.8	0.9	2.6	0.2	-0.9	-0.8	0.2	0.1	1.6	-1.1	-1.0	-1.4
Qualifications: College or University degree	0.2	0.7	1.8	-0.8	0.6	-1.3	-0.1	-0.9	-0.2	0.9	0.7	1.3
Eye problems/disorders: None of the above	1.6	1.8	4.5	-0.9	-2.0	1.8	0.7	0.4	-2.1	-1.1	-0.6	-1.2
Mouth/teeth dental problems: Loose teeth	1.4	1.7	5.7	0.5	-0.0	-0.7	-0.6	-0.2	0.2	-1.9	-2.4	-2.2
Emphysema/chronic bronchitis	0.2	0.2	0.5	-0.1	0.7	-0.3	0.5	-0.1	0.1	-0.5	-0.7	-0.0
Medication for pain relief, constipation, heartburn	0.6	1.0	3.0	0.6	1.3	0.5	-0.6	0.0	1.3	-1.3	-1.7	-0.3
Neck or shoulder pain in last month	1.3	1.9	11.1	-0.8	-0.2	0.7	3.3	1.9	-0.9	0.4	0.6	-0.1
Medication: Blood pressure	0.4	0.6	2.9	-0.3	-1.0	1.2	-0.3	-0.4	-1.7	-0.1	0.2	-0.3
Angina (self-reported)	0.9	1.2	3.4	-0.0	1.1	-0.3	0.4	0.4	1.0	-1.8	-1.8	-1.4
Migraine (self-reported)	0.6	0.7	5.8	-0.1	0.4	2.4	0.3	0.1	0.0	0.6	0.2	0.1
Medication: Ibuprofen	2.5	3.0	10.1	-1.6	0.2	1.6	0.2	-1.1	-0.1	3.2	2.8	1.6
Medication: Allopurinol	0.9	1.2	4.7	-1.6	-0.2	1.6	0.6	-0.4	-2.2	0.1	-0.9	0.2
Medication: Omeprazole	0.5	0.6	1.8	1.2	0.1	-1.4	0.6	0.8	-0.1	-0.4	0.2	-0.8
Medication: Seretide 50 evohaler	3.5	4.0	10.2	-3.2	-0.5	2.9	0.0	-1.9	-0.5	2.5	1.6	2.3
Mean time to correctly identify matches	0.6	1.1	3.4	0.3	1.8	-0.4	0.6	0.4	1.7	0.8	1.3	0.7
Heart disease (mother)	0.6	0.8	3.4	-0.8	-1.8	0.5	-0.2	-0.4	-1.3	-0.2	-0.7	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	5.6	-2.4	0.6	0.1	0.1	-1.3	0.1	1.9	2.0	2.0
Whole body fat mass	0.4	1.5	8.3	-0.4	-2.9	0.8	1.2	0.5	-1.5	0.2	0.6	-0.2
Leg fat mass (right)	0.3	1.3	6.9	-0.1	-2.6	0.7	1.4	0.8	-1.2	-0.3	0.1	-0.8
Arm predicted mass (right)	0.4	1.9	5.6	-2.4	-1.7	-0.6	0.0	-1.6	-0.5	1.7	1.3	1.1
Pulse rate, automated reading	0.3	1.1	4.0	2.0	-1.4	0.5	0.9	1.2	-0.5	0.3	1.0	-0.3
Alcohol intake frequency.	0.6	1.4	3.6	-1.5	-1.9	-0.1	-1.4	-1.7	-1.3	0.2	0.2	0.4
Comparative height size at age 10	1.0	5.3	16.6	-1.8	-0.2	-0.4	-1.8	-2.4	0.9	3.4	2.6	4.1
Number of full sisters	0.2	0.3	1.2	-1.1	-0.5	-0.2	0.4	-0.5	-0.0	0.4	-0.3	0.7
Suffer from ‘nerves’	1.4	2.2	4.6	1.5	-1.6	-1.1	2.0	2.1	1.0	-1.2	-0.1	-1.5
Overall health rating	0.6	1.3	4.7	0.2	-0.8	0.9	2.2	1.5	-1.3	-0.4	-0.1	-0.9
Chest pain or discomfort	0.4	0.5	2.2	-1.5	-0.0	-0.4	-0.1	-1.0	1.1	0.3	0.2	0.5
Had major operations	0.7	0.9	4.1	-0.7	-2.0	-0.7	1.1	0.5	-0.6	0.1	0.9	-0.0
Age at last live birth	1.1	1.6	3.0	1.7	-0.7	0.0	1.5	1.7	0.1	-1.5	-1.0	-1.6
Family relationship satisfaction	2.0	2.5	6.5	-1.2	0.6	1.0	0.4	-0.8	0.2	2.5	2.4	2.5
Leg pain on walking	0.3	0.4	1.8	0.2	0.5	0.2	-0.6	-0.2	1.4	-0.7	-0.5	-0.5
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.6	4.6	1.9	-0.0	1.3	1.1	2.0	1.6	-1.9	-1.5	-2.2
Commuting to job workplace: Car/motor vehicle	1.9	2.1	4.2	1.8	-1.4	0.5	0.1	1.4	-1.1	-1.8	-1.7	-2.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.0	-0.6	-1.0	-0.7	-0.2	-0.3	-1.0	-0.6	-0.6	-0.3
Medication: Aspirin	0.9	1.1	4.8	-0.7	-1.7	-2.2	-0.5	-0.8	-0.9	-0.4	-0.3	-0.2
Supplements: Vitamin C	0.1	0.2	0.5	-0.5	-0.1	0.1	0.2	-0.2	0.6	0.2	0.5	-0.7
Knee pain experienced in last month	0.5	0.7	2.6	-0.8	-1.6	-0.6	0.9	0.1	-0.5	0.7	0.9	0.3
Hypertension (Self-reported)	0.2	0.7	1.6	0.7	-1.3	-0.8	0.5	0.7	0.5	-1.1	-0.6	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.4	2.1	0.7	-0.3	1.0	1.6	0.8	-0.4	0.7	-1.1
Illnesses of father: Heart disease	0.4	0.5	2.4	-1.2	0.3	-0.1	-0.2	-0.7	-1.5	0.4	0.5	-0.2
Illnesses of siblings: Diabetes	0.3	0.4	0.9	-0.4	0.8	-1.0	-0.5	-0.2	-0.8	-0.5	0.1	-0.4
Smoking status: Previous	0.3	0.4	1.7	-0.6	0.0	0.6	0.1	-0.4	-0.4	-0.7	-0.4	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	4.7	-1.9	0.2	1.2	-1.5	-2.2	-0.0	0.7	-0.6	1.3
Whole body fat-free mass	0.3	1.7	5.3	-2.3	-1.5	-0.2	-0.1	-1.6	-0.8	1.4	1.2	1.0
Leg fat-free mass (right)	0.3	1.5	3.8	-1.9	-1.6	-0.1	0.4	-1.1	-0.6	1.5	1.4	1.0
Arm fat percentage (left)	0.7	2.6	6.2	0.7	-2.5	1.5	1.8	1.8	-1.7	-1.2	-0.7	-1.8
Average weekly red wine intake	0.8	1.2	3.5	1.9	0.3	0.3	0.6	1.5	0.0	-1.0	-0.8	-1.6
Handedness (chirality/laterality): Left-handed	0.5	0.7	2.0	0.6	-0.0	0.7	0.0	0.3	-0.7	-1.4	-0.8	-1.4
Mood swings	2.4	4.3	8.7	-2.3	-2.9	-1.3	-1.9	-2.5	-1.1	2.1	1.7	2.1
Loneliness, isolation	0.7	1.0	5.1	-2.3	-0.0	0.2	0.0	-1.2	-1.5	0.2	0.1	0.3
Long-standing illness, disability or infirmity	0.8	1.2	3.3	1.0	-1.1	0.6	1.8	1.7	-0.2	-0.6	-0.1	-1.2
Ever had bowel cancer screening	0.4	0.5	1.9	0.4	1.4	0.0	0.2	0.3	-0.8	0.3	1.2	0.1
Diabetes diagnosed by doctor	0.6	1.0	2.4	-0.2	-1.5	-1.0	1.1	0.5	0.0	-1.2	-0.7	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	2.4	2.6	5.7	1.8	-0.7	-0.8	2.2	2.2	-0.0	-1.6	-1.0	-2.4
Friendships satisfaction	0.8	0.9	2.0	-0.9	-0.4	-0.1	-0.4	-0.9	-1.0	1.3	1.4	1.4
Qualifications: nursing, teaching	0.8	1.2	2.6	0.4	1.0	-0.6	1.6	1.2	-1.6	-0.9	0.1	-1.4
Commuting to job workplace: Walk	0.7	0.7	2.3	0.1	0.3	1.3	1.5	0.7	0.6	0.9	0.9	0.5
Eye problems/disorders: Cataract	1.2	1.4	5.9	1.7	1.3	-2.4	-0.3	0.6	1.4	0.3	0.3	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.3	0.5	-0.1	1.5	1.0	0.9	0.0	-0.2	-0.8	-0.1
Medication for cholesterol	0.7	1.1	3.2	-0.4	0.5	-0.5	-1.0	-0.9	0.2	1.5	1.4	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.3	0.9	-0.7	-0.5	0.5	0.8	0.6	0.3	1.1	0.8
Back pain experienced in last month	0.2	0.3	0.5	0.1	-0.7	0.7	-0.2	0.3	-0.6	-0.5	-0.5	-0.5
Mineral and other dietary supplements	1.8	2.4	6.1	-2.0	-0.1	0.9	-0.7	-1.6	-1.1	2.0	1.6	2.5
Breast cancer (self-reported)	1.4	1.7	8.5	-1.4	2.9	-0.6	0.2	-0.5	-1.8	0.4	0.8	0.1
Asthma (self-reported)	0.9	1.7	3.7	-1.6	-0.9	0.1	-0.3	-1.3	0.6	1.9	1.7	1.8
Osteoporosis (self-reported)	2.6	3.2	7.3	-2.2	-0.1	0.7	-1.7	-2.0	0.3	2.3	1.9	2.7
Osteoarthritis (self-reported)	0.2	0.3	1.0	-0.2	-0.2	-0.3	1.0	0.4	-0.4	-0.0	1.0	-0.1
Medication: Aspirin	0.7	0.9	4.4	-0.5	-1.6	-2.1	0.2	-0.3	-0.9	-0.4	0.0	-0.4
Medication: Gliclazide	0.5	0.6	3.1	-0.7	0.3	0.6	-0.7	-0.5	-1.8	-0.6	-0.1	-0.6
Illnesses of father: None of the above (group 1)	1.2	1.4	3.8	1.0	-0.5	-2.0	-0.6	-0.0	1.9	-1.2	-1.4	-0.4
Smoking status: Current	0.2	0.4	2.7	0.1	-0.0	0.0	-0.2	-0.2	1.6	0.4	0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	3.9	1.6	0.7	-0.7	0.1	1.4	-0.3	-2.0	-1.2	-1.7
Whole body water mass	0.3	1.6	5.2	-2.3	-1.6	-0.2	-0.1	-1.5	-0.7	1.4	1.1	1.0
Leg predicted mass (right)	0.3	1.6	4.1	-2.0	-1.6	0.1	0.3	-1.1	-0.8	1.5	1.4	1.1
Arm fat mass (left)	0.4	1.5	4.9	-0.0	-2.2	1.3	1.4	1.0	-1.6	-0.5	-0.2	-1.0
Number of self-reported non-cancer illnesses	0.2	0.4	1.1	-0.2	-0.3	-0.7	0.8	0.1	1.1	0.6	0.8	-0.1
Average weekly champagne plus white wine intake	0.5	0.7	2.5	-0.2	1.6	1.5	0.5	0.2	1.0	0.1	0.5	0.1
Miserableness	0.7	1.2	3.5	-1.2	0.2	-0.8	-1.9	-1.8	-0.1	0.8	0.1	1.0
Guilty feelings	0.4	0.5	1.1	-0.5	0.0	-0.8	0.7	-0.1	1.0	1.0	0.9	0.8
Wears glasses or contact lenses	0.5	0.6	3.0	-0.6	-0.4	-0.2	0.7	0.1	-0.5	0.9	1.7	0.4
Ever taken oral contraceptive pill	0.4	0.4	1.9	-0.2	0.3	0.0	-1.1	-0.5	-1.4	-0.4	-0.4	-0.4
Hearing aid user	1.2	1.4	5.5	-0.2	0.3	-1.3	1.1	0.6	0.1	1.5	2.4	1.1
Mother’s age at death	0.5	0.6	1.9	0.6	-0.3	0.1	1.4	0.7	-0.8	0.5	1.2	-0.0
Financial situation satisfaction	0.8	0.9	2.1	1.3	-0.1	-0.7	1.1	1.4	-0.3	-0.9	-0.8	-1.3
Tinnitus: Yes, now most or all of the time	1.2	1.4	3.7	-1.3	-1.8	-0.8	-0.6	-0.7	-1.9	0.7	1.1	0.8
Commuting to job workplace: Public transport	1.9	2.2	5.1	-0.8	0.3	-0.1	-1.1	-1.4	1.3	2.1	2.2	2.3
Eye problems/disorders: Glaucoma	0.6	0.7	4.3	-0.2	2.1	0.1	0.2	-0.2	0.8	0.7	0.9	-0.2
Medication: Blood pressure	0.3	0.6	1.3	-0.2	-1.1	0.7	0.7	0.5	-0.2	-1.1	-1.0	-0.7
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.4	-0.0	0.7	0.2	1.2	0.9	0.6	-1.0	-0.9	-1.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	0.4	0.2	-0.2	-0.3	0.2	0.1	-0.2	-0.2	-0.4
High cholesterol (Self-reported)	0.8	1.4	3.8	-1.5	0.7	-0.2	-1.0	-1.1	-0.1	-1.6	-1.9	-1.0
Medication: Bendroflumethiazide	0.7	1.0	2.5	0.2	-1.1	-0.6	1.0	0.7	1.1	-1.1	-1.6	-1.1
Medication: Paracetamol	1.1	1.6	5.1	-0.3	-0.0	1.2	1.6	1.0	-1.5	1.6	2.3	0.1
Medication: Lisinopril	2.2	2.9	7.9	-1.1	-0.2	0.5	-1.1	-1.4	0.1	2.7	2.8	2.5
Medication: Atorvastatin	1.2	1.5	3.2	-1.6	-0.8	-1.4	-1.5	-1.8	-0.6	-0.7	-1.1	-0.8
Illnesses of father: High blood pressure	1.0	1.2	4.6	-0.2	-0.9	1.8	2.1	1.1	-0.2	-0.0	0.6	-0.6
Alcohol drinker status: Never	1.0	1.3	6.2	-0.0	0.4	-0.6	-1.3	-0.8	2.5	-0.9	-1.1	-0.5
Ever smoked	0.5	1.0	3.0	-1.3	0.3	-0.2	-1.7	-1.7	0.1	-0.6	-0.4	-0.4
Basal metabolic rate	0.3	1.4	3.9	-2.0	-1.9	-0.0	0.0	-1.3	-0.8	1.2	1.0	0.8
Leg fat percentage (left)	0.7	2.4	7.8	0.8	-2.8	1.1	1.7	1.7	-1.7	-1.0	-0.5	-1.5
Arm fat-free mass (left)	0.2	1.2	3.5	-1.9	-1.8	-0.1	0.1	-1.2	-0.8	1.0	0.8	0.8
Number of operations (self-reported)	0.3	0.5	1.4	-0.9	-0.7	0.3	1.2	0.3	-1.2	0.2	0.7	-0.1
Average weekly beer plus cider intake	0.5	0.7	2.3	-1.2	-0.2	0.8	-1.3	-1.5	0.4	0.1	-0.3	0.5
Irritability	0.7	1.2	2.6	-0.8	-0.5	-1.2	-1.5	-1.6	0.5	1.1	0.6	1.4
Risk taking	0.9	1.3	3.2	-1.1	0.6	1.0	1.8	0.2	-0.1	1.3	1.8	0.8
Ever had prostate specific antigen (PSA) test	1.5	1.8	6.3	-0.3	0.5	-0.4	-0.6	-1.0	0.4	2.3	2.5	1.5
Fractured/broken bones in last 5 years	0.9	1.1	5.0	-0.2	-2.2	-1.2	1.1	0.9	-1.1	-0.3	0.5	-0.5
Age started oral contraceptive pill	2.9	3.6	8.7	-1.7	2.3	1.6	-0.0	-0.9	-0.0	2.6	2.3	3.0
Diastolic blood pressure, automated reading	0.4	1.2	3.2	1.8	0.1	0.5	1.4	1.7	-0.1	-0.5	-0.2	-1.5
Ever depressed for a whole week	0.7	0.9	1.8	-0.4	1.2	-0.2	-0.8	-1.2	0.9	1.2	0.5	1.3
Unable to work because of sickness or disability	1.1	1.5	2.8	1.2	1.5	-0.7	1.7	1.5	0.6	-1.3	-0.9	-1.1
Commuting to job workplace: Cycle	0.4	0.5	2.3	-1.0	1.5	0.4	0.7	0.1	0.1	0.1	-0.2	-0.3
Myopia	1.4	2.1	7.6	0.2	-0.5	0.0	1.6	1.0	-0.0	2.1	2.8	1.7
Vascular/heart problems diagnosed by doctor	0.3	0.8	1.9	-0.5	1.4	0.8	-0.7	-0.7	-0.9	1.2	0.8	0.8
Cholesterol lowering medication	1.0	1.5	4.4	0.6	-0.4	-0.5	0.2	0.4	0.9	-2.1	-1.8	-2.0
Medication: Omeprazole (e.g. Zanprol)	0.7	0.8	2.7	1.6	0.3	-0.8	1.0	1.4	0.1	-0.3	0.1	-0.8
Pain experienced in last month	0.7	1.2	5.4	0.2	2.3	-0.4	-0.9	-0.7	0.9	0.9	0.9	1.2
Supplements: Calcium	0.5	0.5	1.6	-0.6	-0.2	-0.8	-1.3	-1.1	0.7	0.4	0.0	0.6
Basal cell carcinoma (self-reported)	0.4	0.5	1.9	-0.4	0.4	1.0	-1.4	-0.8	-0.1	0.1	-0.6	0.5
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.4	-1.1	-0.9	-1.5	-0.8	-1.4	0.4	0.2	-0.0	0.5
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	2.9	1.3	0.2	-1.1	1.6	1.7	0.5	0.5	1.4	-0.6
Heart disease (siblings)	0.2	0.2	1.2	0.0	-0.3	-0.5	0.0	0.4	-0.3	0.2	1.1	-0.5
Alcohol drinker status: Previous	0.8	0.9	3.6	-0.8	0.2	1.8	-0.0	-0.5	-1.9	0.0	0.1	-0.0
Pack years of smoking	0.3	0.5	2.1	0.1	1.1	0.2	-0.6	-0.7	1.5	0.1	0.2	0.3
Impedance of whole body	0.2	0.9	2.8	1.0	0.7	-0.3	-1.4	-0.5	0.6	0.9	0.5	1.7
Leg fat mass (left)	0.4	1.6	7.0	-0.0	-2.6	0.9	1.6	1.1	-1.4	-0.2	0.2	-0.8
Arm predicted mass (left)	0.2	1.1	3.2	-1.8	-1.6	-0.1	0.1	-1.2	-0.6	1.0	0.8	0.7