Hub : Genes

TBC1D14

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Tibial 0.1608 0.0475 4.3e-04 0.073 NA 0.060 NA 0.080 2.3e-06 NA 1.8e-05 NA 7.8e-07
2 GTEx Brain Caudate basal ganglia 0.3900 0.1160 4.4e-03 0.014 NA -0.003 NA -0.010 1.3e-01 NA 4.0e-01 NA 8.4e-01
3 GTEx Brain Frontal Cortex BA9 0.4113 0.1283 6.3e-03 -0.010 NA 0.002 NA -0.005 7.9e-01 NA 2.9e-01 NA 4.5e-01
4 GTEx Esophagus Mucosa 0.2550 0.0500 7.5e-08 0.215 NA 0.197 NA 0.237 2.0e-14 NA 3.3e-13 NA 6.9e-16
5 GTEx Skin Sun Exposed Lower leg 0.1080 0.0430 7.7e-03 0.079 NA 0.065 NA 0.072 4.2e-07 NA 4.2e-06 NA 1.5e-06
6 GTEx Stomach 0.2540 0.0830 6.5e-03 0.011 NA 0.011 NA 0.035 9.6e-02 NA 9.0e-02 NA 8.8e-03
7 NTR Blood 0.0537 0.0132 9.6e-07 0.026 0.020 0.022 0.021 0.022 4.8e-09 2.4e-07 9.5e-08 1.4e-07 7.5e-08
8 YFS Blood 0.1965 0.0264 0.0e+00 0.182 0.137 0.177 0.191 0.182 2.3e-57 1.7e-42 1.6e-55 2.6e-60 3.5e-57
9 TCGA Thyroid Carcinoma 0.0640 0.0350 3.9e-04 0.040 0.040 0.044 NA 0.052 8.2e-05 8.5e-05 4.0e-05 NA 7.6e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.5 0.8 1.9 -1.1 -0.2 0.3 -1.0 -1.2 0.6 0.8 0.0 1.4
Bipolar Disorder or Schizophrenia 0.5 1.1 5.1 -0.5 -0.4 0.4 0.1 -0.6 1.6 1.2 0.6 2.3
Depressed Affect (Nagel 2018) 1.4 2.9 6.4 -1.9 -0.3 -1.0 -2.1 -2.5 0.8 2.1 1.4 1.9
Depression (Nagel 2018) 0.8 1.1 3.3 -0.8 0.5 0.3 -0.2 -1.0 0.7 1.8 1.6 1.4
Intelligence (Savage-Jansen 2018) 0.4 1.4 3.4 0.3 1.8 0.3 1.6 1.5 -1.8 -0.3 -0.2 -0.8
Neuroticism (Nagel 2018) 0.7 1.7 2.7 -0.4 -1.0 -1.6 -1.4 -1.1 1.4 1.4 1.2 1.7
Schizophrenia (2018) 0.4 0.9 3.2 0.3 -0.3 0.2 0.9 0.2 1.5 0.9 0.7 1.8
Schizophrenia vs Biploar Disorder 0.3 0.4 1.7 0.4 -1.3 -0.2 0.3 0.0 -0.6 0.6 0.9 0.2
Worry (Nagel 2018) 0.3 0.7 2.3 0.4 -1.4 -0.5 -0.2 0.1 1.5 0.6 0.4 0.9
Alzheimer’s Disease (in mother) 1.8 2.1 7.5 2.7 -0.1 -1.2 1.1 2.3 0.3 -1.1 -0.3 -1.3
Alzheimer’s Disease (in father) 0.8 0.9 1.9 -1.4 -0.4 1.2 0.7 -0.5 -0.0 1.2 1.3 0.5
Alzheimer’s Disease (including proxy) 1.4 2.0 5.3 2.2 -0.3 -0.4 2.0 2.3 0.8 -0.6 0.5 -1.4
Crohns Disease (2017) 1.7 3.6 10.9 0.5 -3.3 -2.9 -2.3 -1.3 -0.2 -1.4 -2.1 0.0
Irritable Bowel Disease (IBD) 1.4 3.4 6.7 0.1 -2.6 -2.3 -2.4 -1.5 -0.5 -2.1 -2.4 -0.7
Ulcerative Colitis (UC) 0.6 1.1 3.4 0.2 -0.7 -0.5 -1.1 -0.6 -0.4 -1.8 -1.7 -1.0
Major Depression (MDD) 1.4 1.7 8.9 -1.1 0.0 1.8 -0.3 -0.3 -3.0 -0.4 -0.5 -1.1
Reaction Time 0.4 0.7 3.4 -0.1 1.8 -0.1 0.9 0.3 1.3 0.4 0.6 0.4
Verbal and Numeric Reasoning (VNR) 0.6 1.5 3.9 0.8 0.5 2.0 1.7 1.6 -1.5 -0.4 -0.0 -1.0
Breast Cancer 0.4 1.0 4.1 0.4 2.0 1.1 -0.4 0.0 -0.1 -0.7 -1.4 -0.7
Ovarian Cancer 0.8 1.0 3.6 0.6 0.7 -0.1 0.6 0.2 1.9 1.4 0.9 1.1
Prostate Cancer 1.1 1.5 7.2 1.2 -2.7 -1.1 0.5 0.8 -0.1 -1.0 -0.5 -1.4
Age at First Birth 2.8 4.1 22.0 -2.4 -0.8 2.0 0.6 -0.5 -4.7 1.3 0.6 1.3
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.3 0.4 1.2 0.6 0.3 -0.4 -0.4 0.2 -1.1 -0.7 -1.0 -0.3
Coronary Artery Disease (CAD) 1.3 1.6 4.6 0.1 -0.2 1.1 -1.5 -0.8 -0.7 -1.8 -2.1 -1.2
Crohns Disease (2012) 2.5 4.1 13.5 0.0 -2.0 -3.7 -2.9 -1.7 0.8 -1.5 -2.2 0.3
Mean Putamen Volume 0.3 0.4 0.9 -0.5 0.9 0.9 0.6 0.4 -0.6 -0.0 -0.3 -0.9
Fasting Glucose 2.7 3.2 6.1 2.0 -1.6 -0.8 1.6 2.5 -1.3 -2.0 -1.0 -2.5
HbA1C 2.3 2.5 4.8 -2.0 -0.5 1.2 -1.1 -2.1 -1.3 1.9 1.1 2.2
HDL Cholesterol 0.2 0.3 1.0 0.3 -0.1 -1.0 -0.5 -0.2 0.4 -0.5 -0.8 0.1
LDL Cholesterol 2.1 3.4 7.6 -2.5 -0.0 0.6 -2.4 -2.8 -2.2 1.5 1.0 1.6
Lupus 0.5 0.7 2.8 1.7 0.8 -0.3 -0.3 0.3 0.7 0.7 0.5 1.2
Neuroticism (2016) 0.1 0.1 0.6 0.3 -0.2 -0.8 -0.2 -0.4 0.2 -0.1 0.2 -0.2
Primary Biliary Cirrhosis 0.7 1.0 2.9 0.1 -1.3 -1.4 0.9 0.9 -1.7 0.0 0.2 -0.7
Rheumatoid Arthritis 1.6 2.2 5.5 2.4 -1.6 1.6 0.8 2.0 -0.7 -1.4 -0.7 -1.1
Schizophrenia (2014) 0.2 0.4 2.2 -0.4 -0.1 0.1 0.5 -0.4 0.8 0.5 0.0 1.5
Triglycerides 0.2 0.3 1.3 -0.4 -0.6 0.8 0.5 0.3 -1.1 -0.1 -0.2 -0.2
Type 2 Diabetes (T2D) (2012) 0.6 0.7 2.2 0.4 -0.1 0.2 0.4 0.6 -0.1 -1.2 -1.5 -1.5
Ulcerative Colitis 1.4 2.0 5.5 0.4 -0.7 -0.9 -1.9 -0.8 0.5 -2.2 -2.3 -1.5
Blood Eosinophil Count 0.3 2.6 7.6 1.2 0.4 1.1 2.8 2.2 -0.1 -1.4 -1.0 -2.2
Blood Platelet Count 0.9 10.8 38.8 -2.6 -0.6 -2.8 -2.6 -3.9 2.8 3.3 1.7 6.2
Blood Red Count 0.4 3.8 11.7 1.7 -1.3 -0.6 2.1 2.4 -0.3 -2.3 -1.3 -3.4
Blood White Count 2.4 18.1 52.6 -2.7 -0.8 0.1 0.2 -2.6 1.9 7.2 6.7 6.9
Heel T-Score 0.6 4.5 12.1 2.0 -0.4 0.9 1.3 2.0 -0.5 -3.0 -3.5 -2.8
BMI 0.6 3.7 10.0 0.9 -2.4 0.5 3.2 2.7 -1.6 -1.4 -0.5 -2.0
Height 0.8 15.1 34.7 -3.4 -1.2 -1.7 -3.7 -5.2 0.9 5.4 3.8 5.9
Waist Hip Ratio (WHR) 1.3 5.7 17.0 2.4 -0.4 -0.1 0.6 2.0 -0.8 -3.8 -2.9 -4.1
Systolic Blood Pressure 0.5 2.7 5.8 1.3 -1.1 1.7 1.1 1.5 -1.5 -1.8 -2.0 -2.4
Smoking Status 0.2 0.4 1.3 -0.7 -0.6 0.3 -0.2 -0.7 0.6 -0.5 -0.7 -1.1
Allergy or Eczema 0.6 1.5 7.5 1.0 -1.6 -2.7 0.5 0.7 1.1 -0.1 0.2 -0.5
Cardiovascular Disease 0.5 1.5 3.3 0.1 -1.0 -0.3 1.3 1.0 -1.1 -1.8 -1.4 -1.8
Hypothyroidism (self reported) 0.4 1.0 2.3 -1.5 -0.6 0.5 -1.5 -1.4 -1.0 -0.5 -0.5 -0.1
Respiratory disease 0.5 1.0 2.4 -1.3 -1.1 -0.3 0.8 -0.6 -0.3 1.6 1.3 1.2
Type 2 Diabetes (T2D) (2018) 0.6 1.2 3.0 -0.1 -1.7 -0.9 0.8 0.3 -0.3 -1.3 -1.3 -1.7
Lung FEV1/FVC ratio 0.1 0.4 1.0 -0.3 -1.0 -0.6 0.7 0.4 -0.9 0.1 0.9 -0.2
Lung FVC 0.5 2.4 6.7 2.6 0.3 0.2 0.6 2.0 -0.3 -2.0 -1.3 -2.2
Neuroticism 0.7 1.7 4.4 -1.5 -1.4 -0.8 -2.1 -2.1 -0.3 0.9 0.4 0.8
Chronotype (morning person) 0.3 0.7 1.6 0.6 -1.1 0.5 0.6 0.7 0.1 -1.2 -1.1 -0.6
Hair Pigment 0.1 1.6 4.5 0.7 -0.5 -1.3 -0.2 0.6 -2.1 -1.4 -1.1 -1.9
Tanning 0.0 0.4 0.7 0.1 0.8 0.7 -0.7 -0.5 0.7 0.5 0.8 0.6
Hand grip strength (left) 0.3 0.8 1.7 1.3 1.0 0.7 1.2 1.3 0.8 -0.0 -0.3 -0.0
Number of treatments/medications taken 0.3 0.5 1.6 -0.8 -0.3 0.3 0.9 -0.1 -0.7 0.9 1.3 -0.3
Average weekly spirits intake 0.4 0.5 1.5 -0.5 1.2 0.0 0.2 0.0 -0.3 -0.7 -0.7 -1.2
Sensitivity / hurt feelings 0.3 0.4 1.9 -0.3 -0.6 -0.6 -1.4 -1.0 0.0 -0.4 -0.5 -0.0
Frequency of depressed mood in last 2 weeks 0.2 0.3 0.8 -0.8 0.2 0.1 -0.6 -0.8 0.4 -0.5 -0.9 -0.1
Hearing difficulty/problems: Yes 1.1 1.7 4.6 0.1 -0.2 -0.2 2.1 1.3 1.2 1.6 2.1 0.9
Relative age of first facial hair 1.1 2.2 5.4 -1.4 0.8 1.8 -0.6 -1.2 0.7 1.9 1.8 2.3
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 1.2 1.1 -0.7 -0.8 -0.2 0.5 0.0 0.1 0.5 -0.2
Ever used hormone-replacement therapy (HRT) 0.7 0.9 4.6 -0.3 1.4 2.2 -0.1 -0.1 -0.3 0.7 0.5 0.6
Ever had hysterectomy (womb removed) 0.4 0.5 1.0 -0.4 -0.2 1.0 -0.7 -0.6 0.7 1.0 0.5 0.8
Systolic blood pressure, automated reading 0.4 1.1 2.4 1.6 0.4 0.9 1.2 1.5 0.4 -0.7 -0.6 -1.6
Eye problems/disorders: Diabetes related eye disease 0.4 0.5 2.2 -0.1 -1.5 0.8 0.7 -0.1 0.4 -0.4 -0.7 -0.2
Angina 1.0 1.3 3.4 -0.2 1.4 -0.4 0.6 0.4 1.0 -1.8 -1.8 -1.3
Medication for hormone replacement therapy 0.6 0.7 2.0 0.8 -0.9 1.1 0.1 0.4 -1.1 0.0 0.1 -1.4
Vitamin and mineral supplements 1.6 2.2 6.5 -1.8 -0.1 0.1 -2.5 -2.6 -0.1 0.4 -0.5 1.7
Supplements: Zinc 0.4 0.5 1.8 0.7 0.3 0.0 -0.5 -0.3 0.7 1.0 1.4 0.0
Medication: Co-codamol 1.4 1.6 4.1 1.7 -0.6 1.3 1.7 2.0 0.5 -0.8 -0.7 -1.1
Medication: Metformin 0.8 1.1 3.8 -0.4 -2.0 -0.5 0.3 -0.1 -1.4 -1.3 -1.0 -1.0
Diabetes (father) 2.2 2.7 10.4 1.8 -0.3 1.2 3.2 2.8 -0.1 -0.3 0.6 -0.6
Diabetes (mother) 0.5 0.7 1.8 -0.9 -1.3 1.3 -0.0 -0.3 -0.9 -0.6 -0.0 -0.9
Severe depression (siblings) 0.8 0.9 2.7 -1.1 0.8 0.7 -0.2 -0.8 0.2 1.5 0.7 1.6
Pack years adult smoking proportion 0.4 0.5 2.2 0.1 1.1 0.6 0.0 -0.4 1.5 0.5 0.7 0.5
Impedance of leg (right) 0.1 0.5 1.6 1.0 0.5 -0.3 -1.3 -0.4 0.6 0.3 0.0 0.9
Leg fat-free mass (left) 0.3 1.4 3.8 -1.9 -1.6 0.1 0.4 -1.1 -0.7 1.4 1.4 0.9
Trunk fat percentage 0.3 1.3 5.8 0.2 -2.4 1.0 1.1 0.8 -1.4 0.5 0.9 0.1
Hand grip strength (right) 0.3 0.8 2.2 1.5 0.4 -0.5 1.0 1.2 1.4 0.3 -0.3 0.3
Townsend deprivation index at recruitment 1.3 1.9 3.9 0.5 -0.9 -0.7 1.4 1.3 -2.0 -1.8 -1.3 -1.6
Current tobacco smoking 0.2 0.3 1.6 -0.3 -0.1 0.2 -0.6 -0.6 1.3 0.5 0.4 0.4
Average weekly fortified wine intake 0.8 0.9 3.3 -1.3 0.2 1.8 0.2 -0.6 -0.2 1.1 1.0 0.8
Maternal smoking around birth 0.1 0.2 0.5 -0.6 -0.7 -0.0 -0.3 -0.3 -0.5 0.3 0.3 0.2
Fed-up feelings 0.3 0.5 1.5 -0.8 -0.5 -0.6 -1.1 -1.2 0.0 0.5 0.2 0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 2.6 -0.4 0.6 0.1 -1.6 -1.4 0.7 0.7 0.2 0.9
Relative age voice broke 0.4 0.5 2.0 -0.6 0.1 1.2 0.1 -0.2 0.0 0.7 1.4 0.7
Taking other prescription medications 1.0 1.5 4.4 1.0 -0.6 -0.9 2.1 1.5 0.8 -0.8 -0.4 -1.7
Age when periods started (menarche) 0.9 2.0 4.1 -0.9 0.1 1.7 -1.9 -2.0 -0.2 1.8 0.9 1.7
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 2.6 -0.9 0.2 0.7 -0.7 -1.2 0.3 1.6 1.4 1.3
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.5 9.4 -0.4 0.0 3.1 1.7 1.3 -1.8 -1.1 -1.5 -1.5
Tinnitus: Yes, but not now, but have in the past 0.1 0.1 0.5 0.5 0.2 0.7 -0.2 0.1 -0.1 -0.2 0.0 -0.2
Qualifications: CSEs or equivalent 0.8 1.0 2.8 -0.6 -1.7 -0.0 -1.4 -1.3 0.0 -0.3 -1.6 0.2
Serious illness, injury or assault to yourself 0.4 0.5 1.4 -0.3 1.2 -0.5 -0.7 -0.8 1.0 -0.4 -0.4 -0.3
High blood pressure 0.2 0.7 2.7 0.6 -1.6 -0.4 0.4 0.6 0.7 -1.0 -0.6 -0.6
Hayfever, allergic rhinitis or eczema 0.7 1.4 7.2 0.6 -2.0 -2.7 -0.1 0.2 1.1 -0.0 0.1 -0.1
Multivitamins +/- minerals 1.3 1.7 5.7 1.0 0.3 1.0 2.4 2.1 -0.8 0.2 1.1 -1.1
Stomach or abdominal pain in last month 1.5 1.9 4.2 0.7 -1.2 0.5 1.8 2.0 -1.7 -1.3 -0.7 -1.6
Supplements: Glucosamine 1.3 1.6 4.6 2.1 1.3 -0.9 0.5 1.3 1.5 -1.0 -0.4 -1.5
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 0.9 0.9 -0.0 0.3 0.2 0.5 0.8 0.6 0.6 0.0
Medication: Atenolol 0.1 0.1 0.2 -0.2 -0.3 -0.4 -0.4 -0.0 -0.2 -0.3 -0.0 0.3
Medication: Levothyroxine sodium 0.9 1.5 4.0 -0.1 0.9 0.6 -0.6 0.1 -1.3 -2.0 -1.7 -1.9
Sitting height 1.3 9.0 23.7 -3.3 0.3 -1.2 -1.6 -3.6 0.5 4.4 3.1 4.9
Chronic bronchitis/emphysema (father) 1.2 1.4 4.8 -0.4 -0.4 -0.4 -0.1 0.0 -0.9 2.0 2.2 1.5
High blood pressure (mother) 0.7 0.9 2.8 -1.1 -1.7 0.7 -0.2 -0.7 -1.3 -0.6 -0.5 -1.1
Body mass index (BMI) 0.7 2.9 5.7 0.5 -2.2 1.1 1.9 1.8 -1.5 -1.8 -1.2 -2.4
Impedance of leg (left) 0.1 0.4 1.7 1.3 0.2 -0.2 -0.8 0.0 0.3 0.2 -0.1 0.8
Leg predicted mass (left) 0.3 1.4 3.8 -2.0 -1.6 0.1 0.3 -1.1 -0.8 1.3 1.2 0.8
Trunk fat mass 0.4 1.5 7.1 -0.5 -2.7 0.8 0.8 0.2 -1.5 0.9 1.2 0.5
Waist circumference 0.5 1.7 6.1 -0.0 -2.5 0.5 0.7 0.7 -1.5 -1.4 -1.0 -1.6
Number of incorrect matches in round 0.5 0.8 4.8 0.5 -0.5 2.2 0.4 0.7 -0.9 0.2 0.2 -0.1
Past tobacco smoking 0.2 0.3 0.8 0.7 -0.5 -0.3 0.1 0.6 -0.4 0.5 0.3 0.9
Alcohol usually taken with meals 1.3 2.1 6.8 1.7 0.2 0.0 2.6 2.6 -0.4 -0.3 0.9 -1.2
Nervous feelings 0.3 0.6 2.4 0.8 -1.6 -0.5 0.2 0.3 1.0 0.4 0.4 -0.5
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 1.4 -1.2 -0.1 -1.2 -0.5 -0.9 -0.2 -0.2 -0.3 0.2
Hearing difficulty/problems with background noise 1.5 2.4 7.1 -1.1 0.3 1.1 1.7 0.7 0.2 2.4 2.7 1.6
Hair/balding pattern: Pattern 2 0.7 0.9 2.9 1.4 -0.4 0.8 1.4 1.7 -0.1 -0.6 -0.3 -0.5
Had menopause 0.1 0.1 0.5 0.1 0.7 -0.6 -0.1 0.3 0.1 0.1 0.2 0.3
Had other major operations 0.6 0.7 1.3 -1.0 -0.8 0.2 0.7 -0.3 -1.0 1.1 1.1 0.6
Forced vital capacity (FVC) 0.2 0.6 3.1 1.8 -0.1 -0.9 -0.2 0.6 0.5 -0.5 -0.5 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 3.3 -0.3 0.8 1.8 1.3 1.0 -0.5 -0.7 -0.8 -0.6
Ever unenthusiastic/disinterested for a whole week 2.1 2.6 4.9 -1.1 1.4 -2.1 -1.9 -2.1 2.2 0.8 0.1 1.4
Qualifications: None of the above 1.0 2.2 7.0 -0.3 -2.6 -2.6 -1.7 -1.2 0.4 -0.7 -0.9 0.0
Financial difficulties in last 2 years 0.1 0.2 0.5 0.7 -0.3 0.1 0.4 0.6 0.4 -0.3 0.3 -0.2
Mouth/teeth dental problems 1.5 2.3 4.8 -2.2 0.1 -0.9 -1.6 -2.0 -1.0 1.6 1.2 1.8
Heart attack 0.5 0.7 2.2 -0.9 -0.8 -1.5 -0.8 -1.3 0.3 0.1 -0.1 0.3
Allergy 0.4 0.9 2.8 0.1 1.1 1.7 -0.5 -0.1 -0.8 -1.1 -1.4 -0.7
Pain all over the body in last month 0.2 0.2 0.8 -0.4 -0.9 0.5 -0.5 -0.4 -0.2 0.3 0.2 0.2
Diabetes (self-reported) 0.8 1.2 2.7 -0.4 -1.5 -0.4 1.0 0.5 -0.3 -1.5 -1.3 -1.6
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.0 0.9 0.4 -0.3 0.9 0.7 0.9 -0.9 -0.9 -1.4
Medication: Ramipril 0.2 0.3 0.9 0.0 0.0 -0.3 -0.5 -0.4 -0.1 -0.9 -0.8 -0.8
Medication: Simvastatin 0.5 0.7 2.7 0.1 -0.6 -0.5 0.3 0.5 -1.0 -1.6 -1.0 -1.0
Fluid intelligence score 0.7 1.5 3.5 1.0 0.8 1.0 1.4 1.5 -1.9 -1.1 -1.0 -1.2
Illnesses of siblings 0.3 0.4 0.9 0.9 0.0 0.3 0.9 0.9 -0.0 -0.6 -0.9 -0.5
Neuroticism score 0.7 1.4 3.4 -1.6 -1.2 -1.1 -1.7 -1.8 -0.4 0.6 0.2 0.6
Weight 0.2 1.1 5.5 -1.1 -2.4 0.4 0.3 -0.5 -1.2 0.6 0.6 0.3
Impedance of arm (right) 0.3 1.6 4.7 0.8 1.1 0.9 -1.8 -0.9 0.6 1.3 0.9 2.2
Arm fat percentage (right) 0.6 2.5 5.2 1.0 -2.3 1.7 1.5 1.8 -1.4 -1.4 -0.9 -1.7
Trunk fat-free mass 0.3 1.7 5.1 -2.2 -1.4 -0.4 -0.5 -1.8 -0.5 1.4 1.1 1.1
Hip circumference 0.3 1.1 4.7 -1.4 -2.2 0.7 0.2 -0.6 -1.1 0.7 0.4 0.8
Time employed in main current job 1.0 1.2 4.2 -0.6 2.0 1.5 1.3 0.7 0.3 0.9 0.7 0.5
Alcohol intake versus 10 years previously 0.9 1.3 2.3 -0.6 -0.4 -1.3 -1.3 -1.3 -0.0 1.5 1.5 1.4
Father’s age at death 0.7 0.9 3.3 0.1 1.2 1.8 0.4 0.6 -1.5 0.3 0.0 0.5
Worrier / anxious feelings 0.3 0.6 2.0 -0.9 -1.1 -0.2 -0.6 -0.4 -0.4 0.7 0.3 1.4
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 0.5 0.7 -0.4 0.1 0.5 0.6 -0.3 -0.4 0.0 -0.5
Falls in the last year 0.2 0.3 1.3 -0.6 0.1 0.6 -0.5 -0.3 -1.2 -0.2 -0.2 -0.0
Hair/balding pattern: Pattern 3 0.7 1.0 2.4 -0.8 0.5 -0.4 -0.3 -1.0 1.5 1.1 1.4 1.3
Number of live births 3.1 4.4 8.7 1.6 -1.4 0.1 2.3 2.5 -1.1 -3.0 -2.3 -2.9
Forced expiratory volume in 1-second (FEV1) 0.2 0.5 2.0 1.4 -0.1 -0.9 0.2 0.9 0.0 -0.6 -0.4 -0.7
Pulse rate 0.4 0.6 2.6 1.0 -1.6 0.6 -0.6 0.0 0.4 -0.6 -0.6 -0.5
Happiness 0.4 0.4 1.8 0.5 0.3 -1.0 0.4 0.2 1.3 0.5 0.3 0.4
Noisy workplace 0.2 0.3 1.9 -0.1 0.5 -1.4 -0.3 -0.3 -0.0 -0.0 0.2 0.2
Qualifications: A levels/AS levels or equivalent 0.3 0.7 4.1 0.3 2.0 1.0 0.3 0.3 -0.2 -0.4 -0.4 -0.5
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.3 1.0 0.5 -0.3 -1.0 -0.2 0.1 -0.9 0.2 0.2 0.4
Mouth/teeth dental problems: Dentures 0.6 1.0 3.5 1.9 0.1 0.3 0.8 1.4 1.4 -0.6 0.2 -0.8
Asthma 0.8 1.5 3.4 -1.4 -0.8 0.0 -0.1 -1.1 0.7 1.8 1.7 1.8
Medication: Ibuprofen (e.g. Nurofen) 1.6 2.0 5.7 -1.6 -0.1 1.5 -0.4 -1.4 -0.3 2.4 2.0 1.3
Medication: Cholesterol lowering 0.6 0.9 2.1 -1.5 -0.8 -1.0 -0.5 -0.8 -1.5 -0.8 -0.7 -0.5
Depression (self-reported) 1.2 1.5 2.8 -0.9 -1.3 -1.6 -1.5 -1.7 -0.5 1.1 0.4 1.3
Medication: Lansoprazole 0.4 0.5 2.0 0.5 0.3 0.2 0.3 0.9 -1.4 0.4 0.9 -0.3
Prospective memory result 0.7 0.9 2.6 -0.4 1.3 -0.4 -0.5 -0.5 0.8 1.0 1.1 1.6
Lung cancer (father) 0.3 0.3 1.2 0.5 -1.1 -0.7 -0.1 0.3 0.4 -0.1 0.5 0.7
Illnesses of mother 1.7 2.1 6.9 -0.1 2.6 -0.5 -0.6 -0.8 1.6 1.7 1.2 1.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.5 1.9 1.4 0.5 0.2 0.8 1.2 -0.6 0.0 0.5 -0.1
Pulse wave Arterial Stiffness index 0.4 0.5 1.2 0.3 0.4 -1.1 0.8 0.5 -1.0 -0.4 -0.0 -0.9
Impedance of arm (left) 0.3 1.3 4.0 0.6 1.3 0.1 -1.5 -0.7 0.4 1.3 0.8 2.0
Arm fat mass (right) 0.4 1.7 4.6 0.3 -2.2 1.5 1.5 1.3 -1.4 -0.9 -0.5 -1.3
Trunk predicted mass 0.3 1.5 4.5 -2.1 -1.4 -0.3 -0.4 -1.7 -0.4 1.3 1.1 1.0
Standing height 1.2 12.1 29.8 -3.1 -0.4 -1.5 -2.9 -4.4 0.7 5.0 3.8 5.5
Length of working week for main job 0.6 0.6 2.3 -1.1 1.5 0.0 0.0 -0.7 -0.8 -0.8 -0.8 -0.4
Exposure to tobacco smoke at home 0.8 0.9 2.5 -1.0 0.7 1.6 0.8 -0.4 -0.4 1.2 1.2 0.7
Breastfed as a baby 0.2 0.2 0.6 -0.8 -0.0 -0.2 0.3 0.2 0.3 0.7 0.7 0.3
Tense / ‘highly strung’ 0.4 0.6 3.3 0.2 -1.1 -0.5 0.1 0.1 1.8 0.6 0.4 0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 4.7 -2.2 1.0 -0.8 -0.7 -1.7 -0.2 1.7 1.1 1.4
Hair/balding pattern: Pattern 4 0.3 0.8 1.4 -0.6 -0.8 -1.2 -0.8 -0.9 -0.6 1.2 1.1 0.8
Birth weight of first child 1.2 2.2 10.1 0.3 -0.4 -0.8 -1.9 -1.3 3.2 1.1 0.4 1.4
Peak expiratory flow (PEF) 0.2 0.5 1.7 -0.2 0.3 -0.1 1.2 1.1 -1.3 -0.3 -0.1 -0.4
Pulse wave reflection index 0.9 1.1 2.7 0.5 1.0 -1.6 1.0 1.1 -1.5 -0.6 -0.1 -1.1
Ever highly irritable/argumentative for 2 days 0.9 1.0 6.3 1.4 0.6 -0.1 -0.2 0.4 2.5 -0.3 0.2 0.5
Loud music exposure frequency 0.2 0.2 0.5 -0.6 -0.4 -0.5 0.1 -0.3 0.1 0.3 0.5 0.7
Qualifications: O levels/GCSEs or equivalent 1.2 1.9 4.7 1.4 1.6 2.2 1.8 2.0 0.4 -0.3 0.3 -0.7
Mouth/teeth dental problems: Bleeding gums 2.7 3.4 7.8 2.1 -1.1 1.0 1.4 2.2 -0.1 -2.4 -2.1 -2.8
Blood clot in the leg (DVT) 0.8 1.1 2.2 1.1 0.3 -1.2 1.4 1.5 0.3 0.7 1.5 -0.3
Medication: Paracetamol 1.1 1.8 6.2 -0.5 0.0 1.3 1.4 0.7 -1.1 2.0 2.5 0.5
Headache pain in last month 0.2 0.4 1.9 -0.9 -0.1 1.4 -0.0 -0.6 -0.6 0.3 0.3 -0.1
Medication for cholesterol, blood pressure or diabetes 0.4 0.6 2.3 1.1 1.0 -0.1 0.6 0.9 1.5 0.1 -0.2 0.2
Glaucoma (self-reported) 0.4 0.5 2.0 -0.2 1.4 -1.3 -0.2 -0.2 0.0 -0.1 0.0 -0.6
Gout (self-reported) 0.9 1.2 2.9 -1.6 -0.5 1.2 -0.0 -0.6 -1.7 -0.7 -1.6 -0.3
Hypothyroidism/myxoedema (self-reported) 0.6 1.1 2.0 -1.0 0.2 -0.3 -1.3 -1.0 -1.1 -1.4 -1.3 -1.3
Medication: Amlodipine 0.5 0.7 1.7 -1.3 -0.0 -1.1 -1.1 -1.3 -0.3 -0.6 -0.3 0.2
Medication: Ventolin 100micrograms inhaler 0.5 0.6 4.6 0.2 0.2 -0.6 -0.3 -0.5 2.1 0.0 0.1 0.7
Birth weight 0.9 2.0 6.7 -0.8 -1.5 -0.3 -0.8 -1.5 0.6 2.0 1.1 2.6
Chronic bronchitis/emphysema (mother) 0.8 0.9 3.5 -0.9 -1.9 -0.2 -0.7 -1.0 -1.2 0.2 0.3 0.6
High blood pressure (siblings) 0.1 0.2 0.4 -0.3 -0.7 -0.4 -0.7 -0.6 0.3 0.1 0.1 0.0
Forced vital capacity (FVC), Best measure 0.1 0.5 2.2 1.5 0.8 0.2 0.5 0.9 0.1 0.4 0.8 0.1
Body fat percentage 0.4 1.6 7.2 0.3 -2.7 1.2 1.3 1.0 -1.7 -0.0 0.4 -0.5
Leg fat percentage (right) 0.5 1.8 6.9 0.6 -2.6 0.9 1.2 1.3 -1.3 -1.0 -0.6 -1.5
Arm fat-free mass (right) 0.2 1.3 3.7 -1.9 -1.8 -0.6 0.4 -1.1 -0.6 1.1 0.9 0.5
Exposure to tobacco smoke outside home 0.1 0.1 0.5 0.1 -0.1 -0.7 0.0 -0.1 -0.4 -0.6 -0.6 -0.1
Comparative body size at age 10 0.1 0.4 1.3 0.5 0.0 -1.1 1.0 0.7 -0.2 0.1 0.4 0.3
Number of full brothers 1.4 1.7 5.2 -0.5 1.0 1.9 -0.3 -0.0 0.0 -1.8 -2.3 -1.4
Worry too long after embarrassment 0.2 0.3 0.7 -0.3 0.2 -0.7 -0.7 -0.4 -0.1 -0.8 -0.9 0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 3.0 -0.6 1.2 -1.7 0.5 -0.3 0.7 1.1 0.7 0.9
Wheeze or whistling in the chest in last year 0.5 0.9 4.7 0.0 0.1 1.0 2.2 0.9 -0.3 0.8 1.0 -0.2
Number of children fathered 0.1 0.1 0.1 -0.3 -0.4 0.2 0.1 -0.2 0.3 0.2 -0.3 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 1.9 2.2 6.5 2.3 0.5 -0.3 2.2 2.5 1.0 -0.4 0.3 -1.2
Age at first live birth 0.3 0.6 2.5 0.2 0.6 1.6 0.7 0.2 -0.5 0.9 0.8 0.4
Pulse wave peak to peak time 0.7 0.8 2.0 -0.6 -0.4 1.0 -0.9 -0.8 1.2 1.0 0.5 1.4
Health satisfaction 0.4 0.6 1.5 0.6 1.2 0.4 0.6 0.7 0.2 -0.9 -0.7 -1.0
Shortness of breath walking on level ground 0.8 0.9 2.6 0.2 -0.9 -0.8 0.2 0.1 1.6 -1.1 -1.0 -1.4
Qualifications: College or University degree 0.2 0.7 1.8 -0.8 0.6 -1.3 -0.1 -0.9 -0.2 0.9 0.7 1.3
Eye problems/disorders: None of the above 1.6 1.8 4.5 -0.9 -2.0 1.8 0.7 0.4 -2.1 -1.1 -0.6 -1.2
Mouth/teeth dental problems: Loose teeth 1.4 1.7 5.7 0.5 -0.0 -0.7 -0.6 -0.2 0.2 -1.9 -2.4 -2.2
Emphysema/chronic bronchitis 0.2 0.2 0.5 -0.1 0.7 -0.3 0.5 -0.1 0.1 -0.5 -0.7 -0.0
Medication for pain relief, constipation, heartburn 0.6 1.0 3.0 0.6 1.3 0.5 -0.6 0.0 1.3 -1.3 -1.7 -0.3
Neck or shoulder pain in last month 1.3 1.9 11.1 -0.8 -0.2 0.7 3.3 1.9 -0.9 0.4 0.6 -0.1
Medication: Blood pressure 0.4 0.6 2.9 -0.3 -1.0 1.2 -0.3 -0.4 -1.7 -0.1 0.2 -0.3
Angina (self-reported) 0.9 1.2 3.4 -0.0 1.1 -0.3 0.4 0.4 1.0 -1.8 -1.8 -1.4
Migraine (self-reported) 0.6 0.7 5.8 -0.1 0.4 2.4 0.3 0.1 0.0 0.6 0.2 0.1
Medication: Ibuprofen 2.5 3.0 10.1 -1.6 0.2 1.6 0.2 -1.1 -0.1 3.2 2.8 1.6
Medication: Allopurinol 0.9 1.2 4.7 -1.6 -0.2 1.6 0.6 -0.4 -2.2 0.1 -0.9 0.2
Medication: Omeprazole 0.5 0.6 1.8 1.2 0.1 -1.4 0.6 0.8 -0.1 -0.4 0.2 -0.8
Medication: Seretide 50 evohaler 3.5 4.0 10.2 -3.2 -0.5 2.9 0.0 -1.9 -0.5 2.5 1.6 2.3
Mean time to correctly identify matches 0.6 1.1 3.4 0.3 1.8 -0.4 0.6 0.4 1.7 0.8 1.3 0.7
Heart disease (mother) 0.6 0.8 3.4 -0.8 -1.8 0.5 -0.2 -0.4 -1.3 -0.2 -0.7 -0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.2 5.6 -2.4 0.6 0.1 0.1 -1.3 0.1 1.9 2.0 2.0
Whole body fat mass 0.4 1.5 8.3 -0.4 -2.9 0.8 1.2 0.5 -1.5 0.2 0.6 -0.2
Leg fat mass (right) 0.3 1.3 6.9 -0.1 -2.6 0.7 1.4 0.8 -1.2 -0.3 0.1 -0.8
Arm predicted mass (right) 0.4 1.9 5.6 -2.4 -1.7 -0.6 0.0 -1.6 -0.5 1.7 1.3 1.1
Pulse rate, automated reading 0.3 1.1 4.0 2.0 -1.4 0.5 0.9 1.2 -0.5 0.3 1.0 -0.3
Alcohol intake frequency. 0.6 1.4 3.6 -1.5 -1.9 -0.1 -1.4 -1.7 -1.3 0.2 0.2 0.4
Comparative height size at age 10 1.0 5.3 16.6 -1.8 -0.2 -0.4 -1.8 -2.4 0.9 3.4 2.6 4.1
Number of full sisters 0.2 0.3 1.2 -1.1 -0.5 -0.2 0.4 -0.5 -0.0 0.4 -0.3 0.7
Suffer from ‘nerves’ 1.4 2.2 4.6 1.5 -1.6 -1.1 2.0 2.1 1.0 -1.2 -0.1 -1.5
Overall health rating 0.6 1.3 4.7 0.2 -0.8 0.9 2.2 1.5 -1.3 -0.4 -0.1 -0.9
Chest pain or discomfort 0.4 0.5 2.2 -1.5 -0.0 -0.4 -0.1 -1.0 1.1 0.3 0.2 0.5
Had major operations 0.7 0.9 4.1 -0.7 -2.0 -0.7 1.1 0.5 -0.6 0.1 0.9 -0.0
Age at last live birth 1.1 1.6 3.0 1.7 -0.7 0.0 1.5 1.7 0.1 -1.5 -1.0 -1.6
Family relationship satisfaction 2.0 2.5 6.5 -1.2 0.6 1.0 0.4 -0.8 0.2 2.5 2.4 2.5
Leg pain on walking 0.3 0.4 1.8 0.2 0.5 0.2 -0.6 -0.2 1.4 -0.7 -0.5 -0.5
Qualifications: NVQ or HND or HNC or equivalent 2.2 2.6 4.6 1.9 -0.0 1.3 1.1 2.0 1.6 -1.9 -1.5 -2.2
Commuting to job workplace: Car/motor vehicle 1.9 2.1 4.2 1.8 -1.4 0.5 0.1 1.4 -1.1 -1.8 -1.7 -2.1
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.0 -0.6 -1.0 -0.7 -0.2 -0.3 -1.0 -0.6 -0.6 -0.3
Medication: Aspirin 0.9 1.1 4.8 -0.7 -1.7 -2.2 -0.5 -0.8 -0.9 -0.4 -0.3 -0.2
Supplements: Vitamin C 0.1 0.2 0.5 -0.5 -0.1 0.1 0.2 -0.2 0.6 0.2 0.5 -0.7
Knee pain experienced in last month 0.5 0.7 2.6 -0.8 -1.6 -0.6 0.9 0.1 -0.5 0.7 0.9 0.3
Hypertension (Self-reported) 0.2 0.7 1.6 0.7 -1.3 -0.8 0.5 0.7 0.5 -1.1 -0.6 -0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.0 1.2 4.4 2.1 0.7 -0.3 1.0 1.6 0.8 -0.4 0.7 -1.1
Illnesses of father: Heart disease 0.4 0.5 2.4 -1.2 0.3 -0.1 -0.2 -0.7 -1.5 0.4 0.5 -0.2
Illnesses of siblings: Diabetes 0.3 0.4 0.9 -0.4 0.8 -1.0 -0.5 -0.2 -0.8 -0.5 0.1 -0.4
Smoking status: Previous 0.3 0.4 1.7 -0.6 0.0 0.6 0.1 -0.4 -0.4 -0.7 -0.4 -1.3
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.6 4.7 -1.9 0.2 1.2 -1.5 -2.2 -0.0 0.7 -0.6 1.3
Whole body fat-free mass 0.3 1.7 5.3 -2.3 -1.5 -0.2 -0.1 -1.6 -0.8 1.4 1.2 1.0
Leg fat-free mass (right) 0.3 1.5 3.8 -1.9 -1.6 -0.1 0.4 -1.1 -0.6 1.5 1.4 1.0
Arm fat percentage (left) 0.7 2.6 6.2 0.7 -2.5 1.5 1.8 1.8 -1.7 -1.2 -0.7 -1.8
Average weekly red wine intake 0.8 1.2 3.5 1.9 0.3 0.3 0.6 1.5 0.0 -1.0 -0.8 -1.6
Handedness (chirality/laterality): Left-handed 0.5 0.7 2.0 0.6 -0.0 0.7 0.0 0.3 -0.7 -1.4 -0.8 -1.4
Mood swings 2.4 4.3 8.7 -2.3 -2.9 -1.3 -1.9 -2.5 -1.1 2.1 1.7 2.1
Loneliness, isolation 0.7 1.0 5.1 -2.3 -0.0 0.2 0.0 -1.2 -1.5 0.2 0.1 0.3
Long-standing illness, disability or infirmity 0.8 1.2 3.3 1.0 -1.1 0.6 1.8 1.7 -0.2 -0.6 -0.1 -1.2
Ever had bowel cancer screening 0.4 0.5 1.9 0.4 1.4 0.0 0.2 0.3 -0.8 0.3 1.2 0.1
Diabetes diagnosed by doctor 0.6 1.0 2.4 -0.2 -1.5 -1.0 1.1 0.5 0.0 -1.2 -0.7 -1.5
Ever had stillbirth, spontaneous miscarriage or termination 2.4 2.6 5.7 1.8 -0.7 -0.8 2.2 2.2 -0.0 -1.6 -1.0 -2.4
Friendships satisfaction 0.8 0.9 2.0 -0.9 -0.4 -0.1 -0.4 -0.9 -1.0 1.3 1.4 1.4
Qualifications: nursing, teaching 0.8 1.2 2.6 0.4 1.0 -0.6 1.6 1.2 -1.6 -0.9 0.1 -1.4
Commuting to job workplace: Walk 0.7 0.7 2.3 0.1 0.3 1.3 1.5 0.7 0.6 0.9 0.9 0.5
Eye problems/disorders: Cataract 1.2 1.4 5.9 1.7 1.3 -2.4 -0.3 0.6 1.4 0.3 0.3 0.1
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 2.3 0.5 -0.1 1.5 1.0 0.9 0.0 -0.2 -0.8 -0.1
Medication for cholesterol 0.7 1.1 3.2 -0.4 0.5 -0.5 -1.0 -0.9 0.2 1.5 1.4 1.8
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.3 0.9 -0.7 -0.5 0.5 0.8 0.6 0.3 1.1 0.8
Back pain experienced in last month 0.2 0.3 0.5 0.1 -0.7 0.7 -0.2 0.3 -0.6 -0.5 -0.5 -0.5
Mineral and other dietary supplements 1.8 2.4 6.1 -2.0 -0.1 0.9 -0.7 -1.6 -1.1 2.0 1.6 2.5
Breast cancer (self-reported) 1.4 1.7 8.5 -1.4 2.9 -0.6 0.2 -0.5 -1.8 0.4 0.8 0.1
Asthma (self-reported) 0.9 1.7 3.7 -1.6 -0.9 0.1 -0.3 -1.3 0.6 1.9 1.7 1.8
Osteoporosis (self-reported) 2.6 3.2 7.3 -2.2 -0.1 0.7 -1.7 -2.0 0.3 2.3 1.9 2.7
Osteoarthritis (self-reported) 0.2 0.3 1.0 -0.2 -0.2 -0.3 1.0 0.4 -0.4 -0.0 1.0 -0.1
Medication: Aspirin 0.7 0.9 4.4 -0.5 -1.6 -2.1 0.2 -0.3 -0.9 -0.4 0.0 -0.4
Medication: Gliclazide 0.5 0.6 3.1 -0.7 0.3 0.6 -0.7 -0.5 -1.8 -0.6 -0.1 -0.6
Illnesses of father: None of the above (group 1) 1.2 1.4 3.8 1.0 -0.5 -2.0 -0.6 -0.0 1.9 -1.2 -1.4 -0.4
Smoking status: Current 0.2 0.4 2.7 0.1 -0.0 0.0 -0.2 -0.2 1.6 0.4 0.5 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 3.9 1.6 0.7 -0.7 0.1 1.4 -0.3 -2.0 -1.2 -1.7
Whole body water mass 0.3 1.6 5.2 -2.3 -1.6 -0.2 -0.1 -1.5 -0.7 1.4 1.1 1.0
Leg predicted mass (right) 0.3 1.6 4.1 -2.0 -1.6 0.1 0.3 -1.1 -0.8 1.5 1.4 1.1
Arm fat mass (left) 0.4 1.5 4.9 -0.0 -2.2 1.3 1.4 1.0 -1.6 -0.5 -0.2 -1.0
Number of self-reported non-cancer illnesses 0.2 0.4 1.1 -0.2 -0.3 -0.7 0.8 0.1 1.1 0.6 0.8 -0.1
Average weekly champagne plus white wine intake 0.5 0.7 2.5 -0.2 1.6 1.5 0.5 0.2 1.0 0.1 0.5 0.1
Miserableness 0.7 1.2 3.5 -1.2 0.2 -0.8 -1.9 -1.8 -0.1 0.8 0.1 1.0
Guilty feelings 0.4 0.5 1.1 -0.5 0.0 -0.8 0.7 -0.1 1.0 1.0 0.9 0.8
Wears glasses or contact lenses 0.5 0.6 3.0 -0.6 -0.4 -0.2 0.7 0.1 -0.5 0.9 1.7 0.4
Ever taken oral contraceptive pill 0.4 0.4 1.9 -0.2 0.3 0.0 -1.1 -0.5 -1.4 -0.4 -0.4 -0.4
Hearing aid user 1.2 1.4 5.5 -0.2 0.3 -1.3 1.1 0.6 0.1 1.5 2.4 1.1
Mother’s age at death 0.5 0.6 1.9 0.6 -0.3 0.1 1.4 0.7 -0.8 0.5 1.2 -0.0
Financial situation satisfaction 0.8 0.9 2.1 1.3 -0.1 -0.7 1.1 1.4 -0.3 -0.9 -0.8 -1.3
Tinnitus: Yes, now most or all of the time 1.2 1.4 3.7 -1.3 -1.8 -0.8 -0.6 -0.7 -1.9 0.7 1.1 0.8
Commuting to job workplace: Public transport 1.9 2.2 5.1 -0.8 0.3 -0.1 -1.1 -1.4 1.3 2.1 2.2 2.3
Eye problems/disorders: Glaucoma 0.6 0.7 4.3 -0.2 2.1 0.1 0.2 -0.2 0.8 0.7 0.9 -0.2
Medication: Blood pressure 0.3 0.6 1.3 -0.2 -1.1 0.7 0.7 0.5 -0.2 -1.1 -1.0 -0.7
Pain type(s) experienced in last month: Hip pain 0.5 0.7 1.4 -0.0 0.7 0.2 1.2 0.9 0.6 -1.0 -0.9 -1.1
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.2 0.4 0.2 -0.2 -0.3 0.2 0.1 -0.2 -0.2 -0.4
High cholesterol (Self-reported) 0.8 1.4 3.8 -1.5 0.7 -0.2 -1.0 -1.1 -0.1 -1.6 -1.9 -1.0
Medication: Bendroflumethiazide 0.7 1.0 2.5 0.2 -1.1 -0.6 1.0 0.7 1.1 -1.1 -1.6 -1.1
Medication: Paracetamol 1.1 1.6 5.1 -0.3 -0.0 1.2 1.6 1.0 -1.5 1.6 2.3 0.1
Medication: Lisinopril 2.2 2.9 7.9 -1.1 -0.2 0.5 -1.1 -1.4 0.1 2.7 2.8 2.5
Medication: Atorvastatin 1.2 1.5 3.2 -1.6 -0.8 -1.4 -1.5 -1.8 -0.6 -0.7 -1.1 -0.8
Illnesses of father: High blood pressure 1.0 1.2 4.6 -0.2 -0.9 1.8 2.1 1.1 -0.2 -0.0 0.6 -0.6
Alcohol drinker status: Never 1.0 1.3 6.2 -0.0 0.4 -0.6 -1.3 -0.8 2.5 -0.9 -1.1 -0.5
Ever smoked 0.5 1.0 3.0 -1.3 0.3 -0.2 -1.7 -1.7 0.1 -0.6 -0.4 -0.4
Basal metabolic rate 0.3 1.4 3.9 -2.0 -1.9 -0.0 0.0 -1.3 -0.8 1.2 1.0 0.8
Leg fat percentage (left) 0.7 2.4 7.8 0.8 -2.8 1.1 1.7 1.7 -1.7 -1.0 -0.5 -1.5
Arm fat-free mass (left) 0.2 1.2 3.5 -1.9 -1.8 -0.1 0.1 -1.2 -0.8 1.0 0.8 0.8
Number of operations (self-reported) 0.3 0.5 1.4 -0.9 -0.7 0.3 1.2 0.3 -1.2 0.2 0.7 -0.1
Average weekly beer plus cider intake 0.5 0.7 2.3 -1.2 -0.2 0.8 -1.3 -1.5 0.4 0.1 -0.3 0.5
Irritability 0.7 1.2 2.6 -0.8 -0.5 -1.2 -1.5 -1.6 0.5 1.1 0.6 1.4
Risk taking 0.9 1.3 3.2 -1.1 0.6 1.0 1.8 0.2 -0.1 1.3 1.8 0.8
Ever had prostate specific antigen (PSA) test 1.5 1.8 6.3 -0.3 0.5 -0.4 -0.6 -1.0 0.4 2.3 2.5 1.5
Fractured/broken bones in last 5 years 0.9 1.1 5.0 -0.2 -2.2 -1.2 1.1 0.9 -1.1 -0.3 0.5 -0.5
Age started oral contraceptive pill 2.9 3.6 8.7 -1.7 2.3 1.6 -0.0 -0.9 -0.0 2.6 2.3 3.0
Diastolic blood pressure, automated reading 0.4 1.2 3.2 1.8 0.1 0.5 1.4 1.7 -0.1 -0.5 -0.2 -1.5
Ever depressed for a whole week 0.7 0.9 1.8 -0.4 1.2 -0.2 -0.8 -1.2 0.9 1.2 0.5 1.3
Unable to work because of sickness or disability 1.1 1.5 2.8 1.2 1.5 -0.7 1.7 1.5 0.6 -1.3 -0.9 -1.1
Commuting to job workplace: Cycle 0.4 0.5 2.3 -1.0 1.5 0.4 0.7 0.1 0.1 0.1 -0.2 -0.3
Myopia 1.4 2.1 7.6 0.2 -0.5 0.0 1.6 1.0 -0.0 2.1 2.8 1.7
Vascular/heart problems diagnosed by doctor 0.3 0.8 1.9 -0.5 1.4 0.8 -0.7 -0.7 -0.9 1.2 0.8 0.8
Cholesterol lowering medication 1.0 1.5 4.4 0.6 -0.4 -0.5 0.2 0.4 0.9 -2.1 -1.8 -2.0
Medication: Omeprazole (e.g. Zanprol) 0.7 0.8 2.7 1.6 0.3 -0.8 1.0 1.4 0.1 -0.3 0.1 -0.8
Pain experienced in last month 0.7 1.2 5.4 0.2 2.3 -0.4 -0.9 -0.7 0.9 0.9 0.9 1.2
Supplements: Calcium 0.5 0.5 1.6 -0.6 -0.2 -0.8 -1.3 -1.1 0.7 0.4 0.0 0.6
Basal cell carcinoma (self-reported) 0.4 0.5 1.9 -0.4 0.4 1.0 -1.4 -0.8 -0.1 0.1 -0.6 0.5
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.4 -1.1 -0.9 -1.5 -0.8 -1.4 0.4 0.2 -0.0 0.5
Deep venous thrombosis (DVT) (self-reported) 1.0 1.2 2.9 1.3 0.2 -1.1 1.6 1.7 0.5 0.5 1.4 -0.6
Heart disease (siblings) 0.2 0.2 1.2 0.0 -0.3 -0.5 0.0 0.4 -0.3 0.2 1.1 -0.5
Alcohol drinker status: Previous 0.8 0.9 3.6 -0.8 0.2 1.8 -0.0 -0.5 -1.9 0.0 0.1 -0.0
Pack years of smoking 0.3 0.5 2.1 0.1 1.1 0.2 -0.6 -0.7 1.5 0.1 0.2 0.3
Impedance of whole body 0.2 0.9 2.8 1.0 0.7 -0.3 -1.4 -0.5 0.6 0.9 0.5 1.7
Leg fat mass (left) 0.4 1.6 7.0 -0.0 -2.6 0.9 1.6 1.1 -1.4 -0.2 0.2 -0.8
Arm predicted mass (left) 0.2 1.1 3.2 -1.8 -1.6 -0.1 0.1 -1.2 -0.6 1.0 0.8 0.7