[Hub]/) : Traits : Worry (Nagel 2018) : ← →

chr12:108,763,672-110,704,487

Best TWAS P=2.8e-10 · Best GWAS P=2.42e-10 conditioned to 0.163

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MMAB 0.12 0.09 enet 13 0.08 2.9e-10 5.4 -5.5 3.7e-08 -0.69 0.55 0.45 FALSE
2 GTEx Cells Transformed fibroblasts MMAB 0.07 0.06 enet 9 0.05 7.3e-05 6.0 -6.3 2.8e-10 -0.91 0.01 0.98 TRUE
3 GTEx Colon Transverse KCTD10 0.22 0.12 lasso 11 0.13 1.1e-06 -4.6 -5.4 8.0e-08 -0.72 0.25 0.75 FALSE
4 GTEx Colon Transverse MMAB 0.08 0.07 lasso 2 0.05 1.7e-03 5.4 -5.2 2.0e-07 -0.69 0.30 0.28 FALSE
5 GTEx Nerve Tibial USP30 0.07 0.01 lasso 4 0.01 1.1e-01 4.4 5.5 4.4e-08 0.81 0.04 0.79 FALSE
6 GTEx Thyroid KCTD10 0.06 0.02 enet 12 0.02 9.2e-03 6.2 -5.5 2.9e-08 -0.85 0.02 0.97 FALSE
7 GTEx Thyroid MMAB 0.07 0.00 lasso 6 0.02 5.4e-03 -4.5 -5.6 2.6e-08 -0.77 0.10 0.76 FALSE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma MMAB 0.05 0.01 blup 57 0.02 5.8e-02 4.9 -5.3 1.1e-07 -0.68 0.02 0.71 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MMAB 0.03 0.02 blup 57 0.02 2.2e-03 6.3 -6.0 2.2e-09 -0.74 0.01 0.93 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MMAB 0.04 0.02 blup 53 0.02 5.2e-03 5.4 -5.4 5.4e-08 -0.67 0.01 0.61 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma KCTD10 0.15 0.08 lasso 6 0.08 2.1e-08 5.5 -6.0 1.8e-09 -0.90 0.05 0.95 FALSE