Best TWAS P=7.17e-09 · Best GWAS P=6.74e-08 conditioned to 0.151
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SPECC1 | 0.24 | 0.21 | lasso | 3 | 0.26 | 4.2e-31 | -4.3 | 5.3 | 9.9e-08 | 0.70 | 0.41 | 0.55 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | RP11-78O7.2 | 0.08 | 0.03 | enet | 7 | 0.06 | 4.3e-04 | 4.4 | -5.8 | 7.2e-09 | -0.78 | 0.03 | 0.88 | TRUE |
| 3 | GTEx | Colon Transverse | RP11-78O7.2 | 0.17 | 0.11 | enet | 22 | 0.14 | 4.1e-07 | 5.1 | -5.5 | 3.1e-08 | -0.71 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CCDC144C | 0.01 | 0.00 | blup | 22 | 0.00 | 8.1e-02 | 4.5 | 5.2 | 1.7e-07 | 0.56 | 0.00 | 0.18 | FALSE |