Best TWAS P=4.08e-11 · Best GWAS P=7.7e-10 conditioned to 0.132
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | ORC4 | 0.12 | 0.00 | lasso | 4 | 0.00 | 0.23200 | 5.5 | -5.6 | 2.8e-08 | -0.89 | 0.03 | 0.38 | FALSE |
| 2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ORC4L | 0.07 | 0.04 | blup | 37 | 0.03 | 0.00061 | -5.4 | 6.4 | 2.1e-10 | 0.65 | 0.04 | 0.50 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ORC4L | 0.06 | 0.01 | blup | 37 | 0.03 | 0.00016 | 6.0 | 6.6 | 4.1e-11 | 0.79 | 0.01 | 0.97 | TRUE |