[Hub]/) : Traits : Blood Platelet Count : →

chr1:959,842-3,191,909

Best TWAS P=1.25e-22 · Best GWAS P=5.44e-40 conditioned to 1.84e-11

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Muscle Skeletal	C1orf86	0.20	0.16	lasso	4	0.15	8.0e-15	9.521	9.8	1.2e-22	-0.46	1.00	0.00	TRUE
14	GTEx	Nerve Tibial	SLC35E2	0.21	0.12	enet	26	0.11	2.7e-08	0.024	-5.8	7.0e-09	0.39	0.89	0.08	TRUE
19	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	-1.076	-5.4	6.1e-08	0.25	0.98	0.00	TRUE
6	GTEx	Brain Cerebellum	C1orf86	0.26	0.18	lasso	5	0.16	1.4e-05	9.521	9.7	3.0e-22	-0.42	0.09	0.05	FALSE
12	GTEx	Muscle Skeletal	RP11-181G12.2	0.12	0.13	enet	8	0.14	7.6e-14	9.521	-9.6	1.2e-21	0.51	1.00	0.00	FALSE
9	GTEx	Esophagus Muscularis	RP11-181G12.2	0.23	0.14	lasso	4	0.19	1.0e-11	-6.772	-9.5	1.5e-21	0.54	0.99	0.01	FALSE
2	GTEx	Adipose Subcutaneous	RP11-181G12.2	0.09	0.07	lasso	1	0.05	1.3e-04	9.521	-9.5	1.7e-21	0.45	0.67	0.12	FALSE
16	GTEx	Skin Sun Exposed Lower leg	C1orf86	0.30	0.07	lasso	8	0.13	1.5e-10	9.521	9.5	2.0e-21	-0.37	0.92	0.00	FALSE
13	GTEx	Nerve Tibial	RP11-181G12.2	0.24	0.22	lasso	5	0.21	3.7e-15	9.521	-9.4	3.4e-21	0.46	1.00	0.00	FALSE
4	GTEx	Artery Tibial	C1orf86	0.33	0.17	enet	31	0.18	8.8e-14	9.521	9.2	2.2e-20	-0.37	1.00	0.00	FALSE
17	GTEx	Testis	C1orf86	0.34	0.23	enet	16	0.19	1.2e-08	9.521	9.1	9.7e-20	-0.47	0.99	0.00	FALSE
1	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	9.521	8.6	5.8e-18	-0.35	0.44	0.02	FALSE
18	GTEx	Thyroid	PRKCZ	0.16	0.03	lasso	4	0.08	1.9e-06	10.859	8.6	1.1e-17	-0.45	0.28	0.04	FALSE
7	GTEx	Colon Transverse	C1orf86	0.20	0.10	enet	16	0.10	2.4e-05	10.800	7.2	7.0e-13	-0.39	0.62	0.04	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	C1orf86	0.23	0.12	enet	25	0.20	5.1e-11	9.521	6.6	4.9e-11	-0.30	0.71	0.01	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1orf86	0.03	0.02	blup	49	0.01	1.3e-02	-6.206	-6.3	2.8e-10	0.44	0.10	0.04	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	RP11-181G12.2	0.16	0.02	enet	18	0.01	1.1e-01	-6.111	-6.3	3.9e-10	0.47	0.10	0.16	FALSE
3	GTEx	Artery Aorta	RP11-181G12.2	0.12	0.04	enet	12	0.05	6.3e-04	-6.772	-6.0	2.3e-09	0.38	0.34	0.11	FALSE
10	GTEx	Lung	AL590822.2	0.09	0.00	lasso	3	0.00	2.0e-01	-5.306	-5.6	1.8e-08	0.41	0.09	0.03	FALSE
5	GTEx	Artery Tibial	RP11-181G12.2	0.09	0.02	enet	37	0.03	2.8e-03	9.521	-5.5	4.0e-08	0.35	0.10	0.25	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1orf86	0.04	0.02	lasso	5	0.02	1.5e-03	-6.164	-5.2	1.7e-07	0.37	0.06	0.10	FALSE