Best TWAS P=6.83e-12 · Best GWAS P=6.74e-13 conditioned to 0.022
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PPAP2B | 0.07 | 0.05 | lasso | 4 | 0.04 | 2.5e-05 | -6.4 | -6.2 | 4.5e-10 | 0.84 | 0.07 | 0.91 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | PPAP2B | 0.10 | 0.05 | enet | 6 | 0.06 | 4.2e-08 | -6.4 | -6.9 | 6.8e-12 | 0.91 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PPAP2B | 0.08 | 0.02 | lasso | 6 | 0.05 | 1.5e-06 | -4.1 | -5.5 | 4.8e-08 | 0.68 | 0.32 | 0.67 | FALSE |