Best TWAS P=2.68e-09 · Best GWAS P=1.16e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | RP11-91A18.4 | 0.10 | 0.07 | lasso | 3 | 0.03 | 1.1e-02 | -5.5 | -5.5 | 3.2e-08 | 0.88 | 0.02 | 0.81 | FALSE |
| 2 | GTEx | Testis | NRD1 | 0.12 | 0.16 | enet | 8 | 0.12 | 5.6e-06 | -5.5 | 5.6 | 2.3e-08 | -0.89 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Testis | RP4-657D16.3 | 0.13 | 0.10 | enet | 5 | 0.12 | 4.0e-06 | -5.5 | 5.4 | 6.3e-08 | -0.90 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Whole Blood | NRD1 | 0.08 | 0.03 | lasso | 2 | 0.03 | 4.4e-04 | -5.7 | 6.0 | 2.7e-09 | -0.95 | 0.00 | 0.99 | TRUE |
| 5 | GTEx | Whole Blood | RP4-657D16.3 | 0.07 | 0.02 | lasso | 3 | 0.03 | 3.5e-04 | -5.7 | 5.9 | 4.4e-09 | -0.91 | 0.01 | 0.99 | FALSE |