Best TWAS P=1.76e-09 · Best GWAS P=4.16e-09 conditioned to 0.026
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP11-61I13.3 | 0.08 | 0.00 | enet | 15 | 0.00 | 1.2e-01 | -4.9 | 6.0 | 1.8e-09 | -0.72 | 0.04 | 0.85 | TRUE |
| 2 | GTEx | Adrenal Gland | MOCS1 | 0.18 | 0.17 | enet | 7 | 0.15 | 4.2e-06 | -5.2 | -5.7 | 1.5e-08 | 0.90 | 0.04 | 0.94 | FALSE |
| 3 | GTEx | Thyroid | RP11-61I13.3 | 0.13 | 0.01 | lasso | 3 | 0.01 | 4.0e-02 | -4.9 | 5.8 | 5.2e-09 | -0.74 | 0.02 | 0.94 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MOCS1 | 0.14 | 0.11 | blup | 88 | 0.16 | 2.8e-15 | 5.5 | -6.0 | 2.1e-09 | 0.91 | 0.02 | 0.98 | FALSE |