Hub : Genes

SNX9

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0900 0.0310 6.8e-05 0.058 0.029 0.047 0.037 0.050 1.4e-07 1.6e-04 2.2e-06 2.5e-05 9.7e-07
2 GTEx Artery Aorta 0.1380 0.0540 2.7e-03 0.005 NA 0.001 NA 0.004 1.6e-01 NA 2.9e-01 NA 1.9e-01
3 GTEx Testis 0.1360 0.0560 8.8e-03 -0.003 NA 0.006 NA -0.006 4.8e-01 NA 1.7e-01 NA 7.4e-01
4 ROSMAP Brain Pre-frontal Cortex 0.0424 0.0172 3.0e-03 0.007 0.011 0.022 0.013 0.014 4.0e-02 1.2e-02 6.9e-04 7.6e-03 5.3e-03
5 TCGA Esophageal Carcinoma 0.2300 0.1350 7.6e-03 -0.003 0.064 0.080 NA 0.015 4.2e-01 4.5e-03 1.6e-03 NA 1.0e-01
6 TCGA Brain Lower Grade Glioma 0.0502 0.0285 1.9e-04 0.034 0.050 0.038 NA 0.037 7.9e-05 2.4e-06 3.1e-05 NA 4.2e-05
7 TCGA Ovarian Serous Cystadenocarcinoma 0.0940 0.0460 3.5e-03 0.005 0.051 0.013 NA 0.015 1.5e-01 2.4e-04 4.2e-02 NA 3.1e-02
8 TCGA Thyroid Carcinoma 0.0380 0.0180 3.1e-04 0.009 0.030 0.024 NA 0.027 4.1e-02 6.3e-04 1.8e-03 NA 1.1e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.3 0.5 2.5 -0.1 -0.4 -0.7 0.1 0.5 -0.5 1.6 -0.6
Bipolar Disorder or Schizophrenia 0.2 0.6 4.1 -0.1 0.2 -0.6 -0.3 2.0 -0.3 -0.2 0.3
Depressed Affect (Nagel 2018) 0.1 0.2 0.6 -0.4 0.6 -0.2 0.0 0.5 0.2 0.8 -0.2
Depression (Nagel 2018) 1.4 2.1 4.0 -2.0 0.9 -1.7 -1.1 0.1 1.5 1.5 -1.8
Intelligence (Savage-Jansen 2018) 0.4 1.3 8.7 0.3 -3.0 0.9 0.4 -0.7 -0.5 -0.0 0.0
Neuroticism (Nagel 2018) 0.2 0.5 1.4 -0.5 -1.2 -0.9 -0.2 -0.5 0.5 0.6 -0.5
Schizophrenia (2018) 0.5 1.1 4.6 -0.1 0.6 -0.1 -0.6 2.1 0.0 -1.6 0.9
Schizophrenia vs Biploar Disorder 1.2 1.6 4.1 -2.0 -1.5 -0.4 -1.2 0.3 1.9 0.3 -0.9
Worry (Nagel 2018) 0.3 0.6 2.9 0.0 -1.3 0.1 0.4 -1.7 0.1 0.4 -0.2
Alzheimer’s Disease (in mother) 0.9 1.1 2.1 1.4 0.2 0.9 1.4 -0.5 -0.8 -1.0 1.4
Alzheimer’s Disease (in father) 0.8 0.9 2.0 -0.2 1.0 -0.7 -0.1 -1.4 0.1 1.2 -1.4
Alzheimer’s Disease (including proxy) 0.2 0.2 0.9 0.7 0.2 0.1 0.7 -1.0 -0.1 0.1 0.2
Crohns Disease (2017) 1.2 2.5 5.6 2.4 -1.4 0.6 1.4 -0.7 -1.5 -2.0 1.9
Irritable Bowel Disease (IBD) 0.2 0.6 2.1 0.9 -1.5 0.5 0.2 0.7 -0.7 -0.7 0.4
Ulcerative Colitis (UC) 0.3 0.6 3.3 -0.0 -0.9 0.7 -0.2 1.8 -0.3 0.5 -0.3
Major Depression (MDD) 0.8 0.9 2.5 -0.7 0.3 -1.3 -1.2 1.6 0.9 -0.8 0.1
Reaction Time 0.3 0.7 1.5 0.5 -1.2 1.1 1.0 0.5 -0.4 -0.8 0.6
Verbal and Numeric Reasoning (VNR) 0.6 1.5 9.0 0.7 -3.0 1.1 0.2 0.3 -0.4 -0.6 0.7
Breast Cancer 0.3 0.7 2.5 0.1 -0.7 1.6 -0.8 -0.7 0.4 -0.9 -0.4
Ovarian Cancer 1.0 1.4 3.5 -1.4 -0.2 -0.2 -1.6 1.6 1.9 0.3 -0.5
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.6 0.8 2.1 -0.8 0.7 -1.2 -0.8 1.5 0.5 1.0 -0.1
Bipolar Disorder (2011) 1.2 1.2 3.1 0.1 1.0 -0.6 1.8 0.0 -1.4 1.4 -0.9
Body Mass Index (BMI) (2010) 0.3 0.4 0.9 0.2 -0.9 -0.6 -0.1 -0.7 0.5 -1.0 0.2
Coronary Artery Disease (CAD) 1.1 1.4 3.9 1.6 1.2 0.4 2.0 0.1 -1.0 0.5 1.2
Crohns Disease (2012) 1.6 2.5 5.6 1.8 -0.8 1.5 1.5 -0.2 -1.6 -2.4 1.9
Mean Putamen Volume 0.8 0.9 1.9 -0.5 -1.4 0.2 -0.3 0.6 1.2 -1.3 1.2
Fasting Glucose 0.4 0.5 1.3 0.8 -0.6 0.7 0.4 -0.2 -0.2 -0.9 1.1
HbA1C 0.8 0.9 2.3 0.5 -0.8 0.5 1.5 0.5 -1.3 1.2 0.4
HDL Cholesterol 0.5 0.8 2.6 0.7 0.4 1.2 -0.2 0.8 0.2 -1.6 1.1
LDL Cholesterol 0.3 0.5 1.5 -0.8 -0.2 -0.6 -0.1 1.2 -0.3 1.1 -0.2
Lupus 0.3 0.4 1.0 -0.7 -1.0 0.1 -0.4 0.3 0.2 1.0 -0.5
Neuroticism (2016) 1.4 2.0 5.6 1.1 0.2 2.4 1.1 -2.0 -1.3 -1.3 0.8
Primary Biliary Cirrhosis 0.9 1.3 2.4 0.9 -1.6 1.2 1.4 -0.3 -1.0 -0.9 1.3
Rheumatoid Arthritis 0.3 0.4 1.2 0.1 0.6 -0.6 0.3 -1.1 0.9 -0.1 -0.0
Schizophrenia (2014) 0.3 0.7 3.2 -0.4 0.5 -0.1 -0.1 1.8 -0.3 -1.1 0.5
Triglycerides 0.5 0.8 1.4 -0.4 0.8 0.4 1.0 -0.9 -1.2 1.2 -0.7
Type 2 Diabetes (T2D) (2012) 1.0 1.2 4.3 0.4 1.1 2.1 0.7 -1.4 -0.9 -0.5 -0.3
Ulcerative Colitis 0.5 0.8 3.7 -0.8 0.1 0.8 -0.6 1.9 0.4 0.7 -0.5
Blood Eosinophil Count 0.1 1.0 1.8 1.4 -0.6 0.8 0.6 -1.1 -1.0 -1.2 1.0
Blood Platelet Count 1.9 21.8 46.6 6.3 -1.7 2.8 6.0 -1.5 -5.0 -3.9 6.8
Blood Red Count 0.3 2.8 9.2 0.6 -2.8 -0.7 0.2 -0.8 0.9 -3.0 1.6
Blood White Count 0.3 2.1 11.4 -0.1 -3.4 0.4 -0.8 -0.6 0.6 -1.9 -0.2
Heel T-Score 1.0 7.6 19.3 2.3 -4.4 3.3 0.8 -1.3 -1.4 -4.0 2.3
BMI 0.1 0.8 2.3 1.1 0.3 1.5 0.6 -1.1 -1.2 -0.1 0.0
Height 0.6 11.6 82.4 1.1 9.1 -1.1 1.6 -0.4 -0.3 1.4 1.9
Waist Hip Ratio (WHR) 0.2 0.7 1.7 -0.6 1.0 -0.7 0.3 -0.8 0.3 1.3 -1.2
Systolic Blood Pressure 0.3 1.7 4.4 0.2 -1.7 2.1 0.4 -1.5 -0.4 -1.8 0.5
Smoking Status 1.5 3.5 7.6 2.7 2.1 0.7 1.9 0.7 -2.2 -0.5 2.6
Allergy or Eczema 1.3 3.4 6.1 -1.9 -0.6 -2.5 -2.4 1.5 2.2 0.6 -2.0
Cardiovascular Disease 0.3 1.1 2.1 0.9 -1.0 1.4 1.3 -0.6 -1.4 -0.2 0.8
Hypothyroidism (self reported) 0.4 1.0 3.5 0.2 -0.4 0.4 1.7 0.2 -1.1 1.9 0.4
Respiratory disease 0.2 0.5 2.4 0.2 -0.5 -0.2 0.7 -1.6 -0.6 0.5 -0.6
Type 2 Diabetes (T2D) (2018) 0.7 1.3 4.6 0.7 0.1 1.6 0.5 1.5 -0.3 -0.8 2.2
Lung FEV1/FVC ratio 0.2 1.1 2.9 1.6 1.1 0.3 0.4 -0.0 -0.7 -1.7 1.2
Lung FVC 0.8 4.1 29.6 -0.0 5.4 -1.6 -0.3 -0.3 0.0 1.0 0.1
Neuroticism 0.1 0.2 0.4 0.4 -0.7 -0.0 0.1 -0.7 -0.3 -0.5 0.0
Chronotype (morning person) 0.1 0.2 0.5 -0.2 -0.3 0.7 0.7 -0.3 -0.6 0.2 0.1
Hair Pigment 0.1 1.7 9.1 0.3 -3.0 -0.0 0.7 -0.9 -1.2 -1.4 0.1
Tanning 0.1 0.7 2.2 -0.1 -0.9 -1.5 -0.7 1.1 0.4 -0.3 0.5
Hand grip strength (left) 0.6 1.6 3.7 1.1 1.9 -0.7 1.5 0.1 -1.1 -0.6 1.9
Number of treatments/medications taken 0.3 0.6 1.9 0.0 -0.8 1.4 -0.2 0.9 0.4 -1.0 -0.4
Average weekly spirits intake 4.0 5.0 10.3 3.1 -1.3 2.9 1.9 -1.9 -3.2 -0.6 1.6
Sensitivity / hurt feelings 0.3 0.4 1.4 -0.5 -1.2 -0.5 -0.5 -0.8 0.3 -0.1 -0.8
Frequency of depressed mood in last 2 weeks 1.0 1.4 3.1 -1.1 0.3 -1.6 -0.5 -1.1 0.8 1.8 -1.5
Hearing difficulty/problems: Yes 1.0 1.6 8.2 -0.4 0.5 0.6 1.0 -0.4 -1.4 2.9 -0.7
Relative age of first facial hair 0.2 0.3 0.8 -0.9 0.6 0.3 -0.8 0.3 0.7 0.1 -0.5
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.3 0.2 -0.3 -0.2 -0.1 -0.0 0.6 0.1 0.1
Ever used hormone-replacement therapy (HRT) 1.3 1.6 4.7 0.6 -2.2 0.8 -0.3 1.1 0.7 -2.1 0.9
Ever had hysterectomy (womb removed) 5.4 6.0 12.0 -3.4 0.7 -1.8 -2.8 1.7 2.6 1.9 -3.5
Systolic blood pressure, automated reading 0.2 0.5 1.9 -0.1 -1.4 0.7 0.2 -0.9 -0.0 -0.5 0.2
Eye problems/disorders: Diabetes related eye disease 0.8 0.8 2.8 -0.7 -0.1 1.1 -1.1 0.8 1.7 -0.2 -0.6
Angina 1.1 1.4 2.8 1.0 1.4 1.7 0.9 -0.6 -1.6 -1.2 0.7
Medication for hormone replacement therapy 1.1 1.2 2.8 1.4 -0.6 0.2 1.0 1.6 -1.7 -0.5 0.8
Vitamin and mineral supplements 0.2 0.3 0.9 0.0 -0.0 -1.0 0.1 -0.9 -0.5 0.1 0.3
Supplements: Zinc 1.1 1.2 2.7 -1.2 0.2 0.6 -1.6 1.0 1.6 -0.7 -1.0
Medication: Co-codamol 0.4 0.4 1.9 -0.3 0.8 0.7 0.3 -1.4 0.1 0.2 -0.2
Medication: Metformin 0.7 1.0 3.9 -0.8 0.1 0.7 -1.0 2.0 1.2 -0.5 0.5
Diabetes (father) 2.5 3.1 9.9 -1.7 0.6 -2.2 -1.9 1.7 3.1 0.1 -0.3
Diabetes (mother) 0.6 0.7 2.4 0.2 1.6 1.0 0.4 -0.7 -0.7 0.6 -0.9
Severe depression (siblings) 0.7 0.7 3.2 0.0 1.4 -0.5 0.5 -1.8 -0.1 0.3 -0.3
Pack years adult smoking proportion 2.2 3.3 7.1 2.3 2.7 0.6 2.3 -1.7 -2.0 -0.1 1.4
Impedance of leg (right) 0.4 2.0 4.8 -1.5 -1.5 -0.3 -0.8 1.2 0.9 2.2 -1.9
Leg fat-free mass (left) 0.6 3.2 11.2 2.0 3.3 -0.3 1.8 -0.7 -1.3 -0.6 2.1
Trunk fat percentage 0.1 0.5 1.4 -0.2 0.7 0.5 -1.0 -0.7 0.5 0.7 -1.2
Hand grip strength (right) 0.9 2.4 8.9 1.0 3.0 -0.1 1.9 -0.6 -1.4 0.1 1.8
Townsend deprivation index at recruitment 0.7 1.0 5.2 -0.1 1.1 0.0 -0.3 -0.1 -0.3 2.3 -1.3
Current tobacco smoking 1.7 2.7 8.1 1.6 2.8 0.7 1.0 0.4 -0.6 -1.3 2.7
Average weekly fortified wine intake 1.7 2.0 4.1 1.8 -2.0 0.1 1.5 -1.3 -1.5 -0.8 1.3
Maternal smoking around birth 1.1 1.6 5.9 0.6 -0.8 2.0 0.4 -2.4 -1.2 -0.7 0.1
Fed-up feelings 0.3 0.6 2.4 0.5 -1.5 1.1 0.4 0.4 -0.6 0.5 -0.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 3.9 -0.6 -0.0 -1.6 0.1 -0.4 0.2 2.0 -1.3
Relative age voice broke 0.7 1.0 2.8 -1.1 0.0 0.5 -0.5 -1.0 0.4 1.5 -1.7
Taking other prescription medications 1.3 2.0 8.3 1.1 -0.3 0.8 1.0 -1.1 -0.9 -2.9 1.6
Age when periods started (menarche) 0.2 0.4 1.2 0.4 0.5 -0.1 1.1 -0.7 -0.1 0.2 1.1
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 3.2 -0.1 -0.0 0.2 -0.8 1.8 0.1 -0.3 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 1.3 2.9 5.6 1.0 -2.1 2.2 1.2 0.9 -0.4 -2.2 2.4
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 0.7 0.2 0.8 -0.7 0.1 0.6 0.6 -0.2 0.6
Qualifications: CSEs or equivalent 0.3 0.4 1.0 0.3 -0.0 0.7 0.9 -0.7 -0.0 0.1 1.0
Serious illness, injury or assault to yourself 0.9 1.0 3.3 -0.1 0.5 0.4 1.5 -1.8 -1.2 1.0 0.1
High blood pressure 0.4 1.1 2.6 0.8 -1.2 1.0 1.6 -1.1 -1.4 -0.2 0.3
Hayfever, allergic rhinitis or eczema 1.5 3.3 5.1 -2.0 -0.8 -1.9 -2.2 1.3 2.2 1.1 -2.3
Multivitamins +/- minerals 0.6 0.8 2.0 1.4 -0.2 0.8 0.7 0.8 -0.4 -1.1 1.0
Stomach or abdominal pain in last month 0.3 0.4 0.9 1.0 -0.2 -0.0 0.9 -0.7 -0.3 -0.3 0.6
Supplements: Glucosamine 0.8 1.1 2.3 -1.0 -0.9 -0.0 -1.4 1.5 1.1 0.1 -1.2
Diverticular disease/diverticulitis (self-reported) 0.8 0.9 4.5 -0.4 -2.1 -0.8 -0.1 1.1 0.0 0.9 0.1
Medication: Atenolol 0.9 1.1 4.0 -0.7 1.1 -1.1 -0.3 2.0 0.0 1.1 -0.8
Medication: Levothyroxine sodium 0.3 0.5 2.4 0.1 0.2 0.3 0.8 0.1 -0.8 1.6 -0.4
Sitting height 0.9 6.1 31.1 1.9 5.6 -0.7 2.4 0.1 -1.0 -0.1 2.7
Chronic bronchitis/emphysema (father) 0.3 0.4 0.8 -0.3 -0.8 0.9 -0.7 0.7 0.0 0.5 -0.5
High blood pressure (mother) 0.9 1.2 3.0 1.0 -1.5 1.7 1.1 -0.3 -0.6 -1.0 0.9
Body mass index (BMI) 0.1 0.5 1.2 1.0 0.1 1.0 -0.1 -1.1 -0.5 -0.7 -0.1
Impedance of leg (left) 0.4 1.9 4.2 -1.6 -1.1 -0.5 -0.8 1.0 1.1 2.1 -2.0
Leg predicted mass (left) 0.6 3.3 11.3 2.1 3.4 -0.3 1.9 -0.7 -1.4 -0.6 2.1
Trunk fat mass 0.1 0.4 2.4 0.4 1.5 0.3 -0.3 -0.5 0.2 0.2 -0.2
Waist circumference 0.0 0.1 0.2 0.3 0.2 0.1 -0.2 -0.4 0.1 0.1 -0.5
Number of incorrect matches in round 1.5 2.5 19.5 -0.2 4.4 -0.2 -0.2 -0.1 0.3 -0.0 0.5
Past tobacco smoking 0.5 0.9 1.8 -1.2 -0.9 0.2 -0.5 -1.1 1.4 0.0 -1.3
Alcohol usually taken with meals 1.5 2.4 4.5 1.6 -2.1 0.6 1.6 -0.3 -1.5 -1.8 2.0
Nervous feelings 0.4 0.7 2.1 -1.0 -1.4 0.2 -0.3 -0.8 0.2 0.8 -1.2
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.5 4.4 1.6 -0.6 -0.8 2.1 -1.1 -1.3 0.6 1.0
Hearing difficulty/problems with background noise 0.2 0.3 1.0 0.2 0.1 -0.8 0.3 -0.5 -0.4 1.0 -0.3
Hair/balding pattern: Pattern 2 0.8 1.0 1.3 1.1 -1.1 1.1 0.8 -0.9 -1.1 -0.9 0.7
Had menopause 0.2 0.2 0.5 -0.4 -0.7 -0.5 -0.5 0.1 0.6 0.1 0.2
Had other major operations 0.3 0.3 1.2 -0.0 -0.6 -0.1 -0.3 0.2 -0.1 -1.1 0.8
Forced vital capacity (FVC) 0.9 3.4 21.6 0.2 4.7 -1.4 0.7 1.1 0.1 0.9 1.1
Heel bone mineral density (BMD) T-score, automated (right) 1.4 3.3 8.6 0.8 -2.9 2.5 1.4 0.9 -0.3 -2.0 2.0
Ever unenthusiastic/disinterested for a whole week 2.1 2.6 4.4 -2.0 -1.0 -1.4 -2.0 1.3 1.7 0.8 -2.1
Qualifications: None of the above 0.7 1.6 4.6 0.7 0.7 1.1 1.8 -2.1 -1.5 0.6 -0.5
Financial difficulties in last 2 years 0.5 0.6 1.4 1.1 0.2 -0.6 1.2 -0.3 -0.9 0.8 0.7
Mouth/teeth dental problems 2.3 3.5 7.0 -2.0 -2.2 -2.0 -1.6 1.1 2.6 1.1 -1.9
Heart attack 2.0 2.5 3.8 1.5 1.5 1.5 1.7 -1.2 -2.0 -1.6 1.7
Allergy 0.4 0.8 1.8 0.8 0.5 0.5 1.3 -0.6 -1.3 -0.1 1.4
Pain all over the body in last month 0.8 0.9 4.9 -0.3 2.2 -0.0 -0.8 -0.9 0.6 -0.1 -0.5
Diabetes (self-reported) 0.2 0.4 1.3 -0.1 -0.0 0.8 -0.2 1.1 0.3 -0.4 0.9
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 2.7 1.6 1.4 0.2 0.7 0.1 -1.4 -0.9 0.7
Medication: Ramipril 0.7 0.9 3.4 0.5 -1.0 1.8 0.3 -0.5 -0.1 -1.4 0.1
Medication: Simvastatin 0.5 0.8 2.0 0.1 1.3 0.9 0.5 -1.4 -1.1 -0.3 0.2
Fluid intelligence score 0.3 0.7 4.0 -0.2 -2.0 0.3 -0.4 0.1 -0.3 0.6 -0.8
Illnesses of siblings 0.5 0.7 2.9 -0.2 1.3 -1.7 0.3 -0.3 0.7 -0.6 0.4
Neuroticism score 0.5 1.0 2.5 1.0 -1.6 0.9 0.8 -1.0 -1.3 -0.0 0.2
Weight 0.2 1.1 5.4 1.2 2.3 0.1 0.7 -0.5 -0.6 -0.1 0.9
Impedance of arm (right) 0.6 3.0 6.0 -2.1 0.0 -1.5 -1.4 1.8 1.6 2.4 -1.9
Arm fat percentage (right) 0.1 0.3 1.1 0.1 0.2 0.4 -1.1 -0.4 0.5 -0.2 -0.9
Trunk fat-free mass 0.8 4.8 13.3 2.5 3.6 0.1 2.4 -0.1 -2.0 -1.2 2.8
Hip circumference 0.0 0.2 0.7 -0.0 0.5 0.0 -0.8 0.6 0.5 0.0 -0.2
Time employed in main current job 0.6 0.7 2.6 0.4 0.8 0.6 0.7 -0.3 -1.0 1.6 -0.3
Alcohol intake versus 10 years previously 0.3 0.5 1.2 -0.1 -0.2 1.0 0.8 -1.1 -0.5 0.8 -0.1
Father’s age at death 1.0 1.3 3.3 -1.4 0.5 -1.0 -1.1 -0.0 1.8 -0.1 -1.6
Worrier / anxious feelings 0.4 0.7 2.0 0.7 -1.1 0.5 1.0 -1.4 -0.4 0.8 -0.3
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 2.5 0.2 -0.1 -0.3 1.6 -1.4 -1.1 1.3 -0.6
Falls in the last year 0.6 0.8 2.9 -0.1 0.9 0.0 0.2 -1.1 -0.1 1.3 -1.7
Hair/balding pattern: Pattern 3 0.2 0.3 1.0 -0.1 0.7 -0.1 0.4 -1.0 0.4 0.5 -0.3
Number of live births 2.9 4.1 7.2 -2.7 -0.7 -1.7 -2.0 2.0 2.6 2.0 -1.8
Forced expiratory volume in 1-second (FEV1) 0.8 2.8 18.0 0.4 4.2 -1.5 0.7 0.6 -0.2 0.3 1.0
Pulse rate 0.5 0.9 2.3 -0.0 0.9 0.4 0.3 -1.1 -0.7 1.5 -1.5
Happiness 0.8 0.9 3.3 -0.3 0.4 -0.6 0.2 -1.0 0.1 1.8 -1.6
Noisy workplace 0.3 0.4 1.6 0.2 0.9 0.3 0.5 -1.2 -0.6 0.3 0.1
Qualifications: A levels/AS levels or equivalent 0.2 0.4 1.4 0.8 0.5 0.1 0.3 0.8 0.1 -0.4 1.2
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 1.0 0.6 -1.0 0.1 0.8 -0.6 -0.6 -0.4 0.4
Mouth/teeth dental problems: Dentures 1.8 3.1 5.2 1.5 2.0 2.3 1.4 -1.6 -2.0 -1.3 1.7
Asthma 0.2 0.4 1.9 0.2 -1.4 0.6 -0.1 -0.2 -0.3 -0.2 -0.8
Medication: Ibuprofen (e.g. Nurofen) 2.7 3.4 12.2 -1.6 -1.0 -0.8 -2.3 3.5 1.8 1.0 -1.3
Medication: Cholesterol lowering 0.4 0.6 2.1 -0.2 0.9 0.8 0.4 -1.4 -0.6 -0.5 -0.1
Depression (self-reported) 0.5 0.6 2.9 -0.1 -0.4 0.6 -0.2 1.7 -0.4 -1.1 0.3
Medication: Lansoprazole 2.4 2.7 8.9 -2.1 -0.5 -1.6 -2.1 1.1 3.0 -0.3 -0.5
Prospective memory result 0.9 1.1 2.2 -1.5 0.9 -0.3 -0.9 0.6 1.3 1.0 -1.5
Lung cancer (father) 0.3 0.3 1.0 0.1 -1.0 -0.3 0.7 -0.2 -0.9 0.3 0.5
Illnesses of mother 2.2 2.7 5.2 -2.0 -0.6 -2.3 -1.8 -0.5 1.6 1.7 -1.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.6 13.8 0.7 3.7 -1.5 0.7 1.2 -0.1 0.0 1.6
Pulse wave Arterial Stiffness index 0.2 0.2 0.8 -0.2 -0.1 0.6 -0.9 -0.1 0.6 -0.3 -0.2
Impedance of arm (left) 0.7 3.3 6.2 -2.4 0.2 -1.5 -1.5 1.4 1.9 2.5 -2.0
Arm fat mass (right) 0.1 0.3 1.7 0.6 1.3 0.3 -0.3 -0.4 0.1 -0.4 -0.0
Trunk predicted mass 0.9 5.0 13.3 2.6 3.6 0.1 2.5 -0.2 -2.1 -1.3 2.8
Standing height 0.5 5.3 26.2 1.2 5.1 -1.6 2.1 1.0 -0.6 0.8 2.4
Length of working week for main job 1.2 1.4 2.6 1.6 0.4 1.3 0.8 -1.5 -1.2 -1.4 0.2
Exposure to tobacco smoke at home 0.7 0.7 2.2 1.3 0.0 0.6 1.5 -0.5 -1.0 -0.4 0.5
Breastfed as a baby 0.4 0.6 2.2 -0.4 -1.5 0.2 -1.2 -0.2 0.5 -0.3 -0.5
Tense / ‘highly strung’ 1.0 1.7 4.3 2.1 0.4 0.1 1.6 -1.4 -1.3 -0.3 1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.7 2.3 0.6 -1.4 -0.0 0.7 -0.6 -1.5 -0.2 0.5
Hair/balding pattern: Pattern 4 0.3 0.7 1.5 -0.3 1.2 -0.5 -0.5 -1.2 0.2 0.8 -1.2
Birth weight of first child 1.2 2.2 4.5 -1.9 0.6 -1.7 -2.1 1.2 1.9 -0.2 -1.1
Peak expiratory flow (PEF) 0.6 1.3 9.7 0.4 3.1 -0.0 0.2 -0.2 -0.3 -0.3 0.5
Pulse wave reflection index 0.4 0.5 1.1 0.2 -1.0 -0.2 -0.7 0.1 1.0 -1.0 0.4
Ever highly irritable/argumentative for 2 days 0.3 0.3 1.4 0.1 0.1 -0.6 -0.3 -1.2 -0.6 0.4 -0.5
Loud music exposure frequency 0.5 0.6 1.2 0.9 -0.2 -1.0 0.9 -0.7 -1.1 -0.0 0.3
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 0.7 0.8 0.1 -0.2 0.0 -0.0 -0.3 -0.0 0.5
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 1.3 -0.2 0.2 1.1 -0.0 0.7 0.1 -0.1 0.6
Blood clot in the leg (DVT) 1.1 1.4 6.0 0.7 2.4 0.8 0.4 -1.7 -0.2 -1.0 0.4
Medication: Paracetamol 0.2 0.3 1.2 0.5 -1.1 0.5 0.0 0.3 -0.5 -0.8 -0.0
Headache pain in last month 0.7 1.3 2.8 1.6 0.8 0.0 1.2 0.5 -0.4 -1.6 1.7
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 1.6 1.0 0.7 -0.4 0.3 0.2 -0.5 0.1 1.3
Glaucoma (self-reported) 0.4 0.4 1.1 -0.2 -0.9 -0.7 -1.1 0.2 0.8 -0.2 -0.5
Gout (self-reported) 0.5 0.7 1.8 -1.2 -0.8 -0.6 -0.5 0.2 0.8 0.8 -1.4
Hypothyroidism/myxoedema (self-reported) 0.5 1.0 2.9 0.4 -0.4 0.7 1.6 -0.3 -1.2 1.7 0.2
Medication: Amlodipine 0.5 0.7 2.0 0.8 -1.1 -0.4 0.3 0.1 -0.5 -1.0 1.4
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.0 -1.0 -1.0 -0.3 -0.3 -0.5 -0.1 0.5 -0.7
Birth weight 0.7 1.5 6.8 0.9 2.6 -0.2 1.0 0.4 -1.1 1.3 0.4
Chronic bronchitis/emphysema (mother) 1.6 1.8 5.4 -1.3 -0.4 -1.2 -1.3 2.3 1.0 1.0 -1.3
High blood pressure (siblings) 0.8 1.1 5.0 0.9 -1.0 2.2 0.2 0.2 -1.4 0.2 -0.1
Forced vital capacity (FVC), Best measure 0.9 3.4 18.0 0.7 4.2 -1.7 0.7 1.6 0.0 0.4 1.6
Body fat percentage 0.1 0.4 1.3 -0.1 0.2 0.6 -0.9 -0.7 0.4 0.5 -1.2
Leg fat percentage (right) 0.1 0.4 1.0 0.1 -0.7 1.0 -0.7 -0.6 0.1 0.3 -0.8
Arm fat-free mass (right) 0.8 3.9 7.6 2.6 2.8 0.2 2.1 -0.6 -1.7 -1.4 2.7
Exposure to tobacco smoke outside home 0.5 0.6 1.7 -0.2 1.3 0.1 0.6 0.2 -0.4 1.3 -1.1
Comparative body size at age 10 0.2 0.6 2.0 -0.7 -0.4 -1.4 -1.1 0.2 0.8 -0.6 -0.0
Number of full brothers 1.1 1.4 2.5 1.2 1.5 0.7 1.5 -0.7 -1.6 -0.3 1.3
Worry too long after embarrassment 0.3 0.5 1.4 0.6 -1.2 0.1 0.5 -1.0 -0.7 -0.7 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.1 -0.6 -1.1 0.5 -0.5 1.1 0.5 -0.1 -0.2
Wheeze or whistling in the chest in last year 2.5 4.4 8.5 2.9 0.4 1.5 2.7 -2.1 -2.6 -1.2 2.2
Number of children fathered 2.5 2.8 6.7 1.9 -0.5 1.1 2.2 -2.1 -2.6 -0.3 1.4
Reason for reducing amount of alcohol drunk: Health precaution 1.1 1.2 2.7 -0.8 0.7 -1.6 -1.6 0.9 0.6 0.7 -1.4
Age at first live birth 1.2 2.2 5.7 -1.7 -0.6 -1.5 -2.4 1.6 1.0 0.7 -1.4
Pulse wave peak to peak time 0.3 0.3 0.8 0.2 0.5 -0.8 0.9 0.2 -0.6 0.3 0.3
Health satisfaction 0.6 0.8 2.1 -0.4 -0.5 -1.2 0.0 -0.7 0.6 1.2 -1.4
Shortness of breath walking on level ground 0.2 0.2 0.7 0.6 -0.5 -0.2 -0.1 -0.0 0.4 -0.8 0.3
Qualifications: College or University degree 0.3 0.9 2.6 0.8 -1.0 -0.6 0.6 1.4 0.1 0.4 1.6
Eye problems/disorders: None of the above 0.6 0.7 4.0 0.3 2.0 -0.9 0.0 0.2 -0.6 0.3 0.3
Mouth/teeth dental problems: Loose teeth 1.1 1.3 4.1 -0.1 1.5 -1.9 -0.1 0.2 0.8 2.0 0.0
Emphysema/chronic bronchitis 1.2 1.3 2.9 1.6 1.7 -0.5 1.4 -1.1 -1.2 0.2 0.6
Medication for pain relief, constipation, heartburn 0.2 0.3 1.3 -0.0 0.3 -0.3 0.6 -1.2 -0.1 -0.1 0.6
Neck or shoulder pain in last month 0.3 0.4 0.8 0.7 -0.3 0.3 0.8 0.6 -0.9 -0.6 0.4
Medication: Blood pressure 0.6 1.1 2.6 -1.5 -1.6 0.2 -0.6 0.6 1.2 0.3 -1.4
Angina (self-reported) 1.0 1.3 2.3 0.8 1.5 1.5 0.8 -0.8 -1.3 -1.4 0.7
Migraine (self-reported) 0.4 0.5 1.6 -1.3 0.6 1.0 -0.2 -0.7 -0.1 0.4 -0.5
Medication: Ibuprofen 2.2 2.6 11.2 -1.2 -1.2 -0.1 -1.9 3.4 1.4 0.5 -0.7
Medication: Allopurinol 0.6 0.8 2.2 -1.4 0.0 -0.3 -1.1 -0.1 0.9 0.0 -1.5
Medication: Omeprazole 0.3 0.3 1.4 -0.1 -1.2 -0.5 -0.4 0.5 0.1 -0.1 -0.6
Medication: Seretide 50 evohaler 0.7 0.8 3.1 -0.6 1.2 -0.2 -0.6 -0.7 -0.0 0.9 -1.8
Mean time to correctly identify matches 0.5 0.9 3.2 0.3 -0.5 1.4 0.6 -0.4 0.1 -1.8 1.0
Heart disease (mother) 0.8 1.0 1.8 1.1 -0.7 1.3 1.2 -0.2 -1.1 -1.2 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.4 0.9 0.6 0.9 -0.9 -0.0 -0.4 -0.2 -0.6 0.9
Whole body fat mass 0.1 0.4 2.3 0.3 1.5 0.4 -0.3 -0.6 0.2 0.1 -0.2
Leg fat mass (right) 0.1 0.2 0.8 0.6 0.9 0.4 0.1 -0.5 -0.1 0.3 0.0
Arm predicted mass (right) 0.7 3.6 8.0 2.4 2.8 0.2 2.0 -0.6 -1.5 -1.3 2.5
Pulse rate, automated reading 0.2 0.6 2.0 0.1 0.9 -0.3 -0.1 -1.4 0.3 0.4 -1.4
Alcohol intake frequency. 2.0 4.7 11.2 -3.3 1.0 -1.1 -2.0 1.2 3.0 2.2 -2.3
Comparative height size at age 10 0.5 2.6 13.5 0.8 3.7 -0.5 1.5 0.3 -0.5 0.4 2.0
Number of full sisters 0.2 0.2 0.7 0.0 -0.9 0.0 0.0 0.0 -0.3 -0.7 0.6
Suffer from ‘nerves’ 0.9 1.5 5.2 0.2 -1.3 1.8 0.9 -2.3 -0.5 0.7 -0.1
Overall health rating 0.8 1.8 5.2 0.8 0.3 0.9 2.3 -1.7 -2.0 1.0 0.2
Chest pain or discomfort 0.6 0.8 2.7 -0.8 1.6 -0.8 0.2 0.5 0.2 1.2 -1.0
Had major operations 0.1 0.2 0.5 -0.3 0.5 -0.1 -0.7 -0.2 0.5 -0.3 -0.3
Age at last live birth 4.6 6.7 11.0 -3.3 -0.3 -2.9 -3.1 3.1 2.9 1.9 -1.9
Family relationship satisfaction 0.2 0.3 0.8 0.8 -0.2 0.5 0.4 -0.3 -0.9 0.3 -0.2
Leg pain on walking 1.9 2.4 5.2 -1.2 0.1 -1.5 -2.0 2.3 1.7 0.8 -1.6
Qualifications: NVQ or HND or HNC or equivalent 1.4 1.6 3.5 -1.6 1.3 -0.8 -1.9 1.3 1.5 -0.1 -0.8
Commuting to job workplace: Car/motor vehicle 0.2 0.3 1.1 0.2 -0.5 -1.1 0.2 -0.1 -0.1 -0.7 0.2
Illness, injury, bereavement, stress in last 2 years 2.9 3.6 10.4 -1.8 0.6 -1.4 -3.2 1.6 2.6 -0.5 -1.7
Medication: Aspirin 1.7 2.2 3.9 1.4 0.8 1.3 1.5 -2.0 -1.8 -1.2 1.4
Supplements: Vitamin C 1.7 2.0 6.5 -1.4 -0.1 0.8 -2.2 0.7 1.2 0.0 -2.5
Knee pain experienced in last month 0.7 1.0 2.2 -1.5 -0.9 -1.5 -0.8 0.4 0.2 1.4 -0.8
Hypertension (Self-reported) 0.3 0.8 1.7 0.7 -1.1 1.1 1.2 -0.5 -1.3 -0.2 0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 2.9 0.1 -1.5 -1.7 0.0 0.6 0.3 -0.1 -0.3
Illnesses of father: Heart disease 1.1 1.5 5.8 1.1 -0.7 0.8 0.5 -0.0 -0.5 -2.4 1.8
Illnesses of siblings: Diabetes 0.2 0.3 0.5 -0.6 0.4 0.2 -0.4 -0.7 -0.4 0.5 -0.7
Smoking status: Previous 0.4 0.5 1.6 0.8 -0.6 -0.6 0.4 0.8 -1.3 0.4 0.5
Forced expiratory volume in 1-second (FEV1), predicted 2.6 5.4 12.5 2.9 1.5 -0.9 3.5 -1.0 -2.4 -0.6 3.5
Whole body fat-free mass 0.8 4.5 12.5 2.5 3.5 -0.1 2.3 -0.5 -1.9 -1.1 2.7
Leg fat-free mass (right) 0.6 3.0 11.8 1.9 3.4 -0.4 1.6 -0.7 -1.1 -0.7 2.0
Arm fat percentage (left) 0.1 0.4 1.3 -0.1 0.2 0.3 -1.1 -0.4 0.7 0.0 -1.0
Average weekly red wine intake 1.4 2.1 5.5 1.9 -0.9 0.1 1.6 0.1 -2.4 -0.5 1.9
Handedness (chirality/laterality): Left-handed 0.9 1.0 1.8 -1.3 -0.6 -1.3 -1.1 0.9 1.2 0.4 -0.9
Mood swings 0.3 0.6 1.2 0.9 -0.4 0.7 0.6 1.1 -1.0 0.1 0.7
Loneliness, isolation 0.6 0.8 4.2 -0.1 2.0 -1.0 0.1 -0.4 0.8 0.2 -0.0
Long-standing illness, disability or infirmity 0.2 0.3 0.8 -0.8 -0.2 -0.4 -0.1 0.4 0.9 0.6 0.1
Ever had bowel cancer screening 0.4 0.5 2.5 0.1 1.6 1.1 -0.2 0.1 0.2 -0.4 0.3
Diabetes diagnosed by doctor 0.3 0.6 2.0 -0.6 0.1 0.7 -0.5 1.4 0.7 -0.6 0.7
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.4 5.0 -1.2 0.2 -1.2 -1.0 2.2 1.5 0.4 0.0
Friendships satisfaction 1.3 1.6 5.4 -0.5 2.1 -2.3 -0.8 0.6 1.2 -0.1 -0.3
Qualifications: nursing, teaching 0.5 0.7 2.1 -0.7 1.1 -0.6 -0.2 1.0 0.4 1.4 -0.7
Commuting to job workplace: Walk 0.3 0.3 1.2 -0.0 0.7 0.4 0.2 -0.6 -0.1 1.1 0.1
Eye problems/disorders: Cataract 0.5 0.6 1.8 0.1 -1.1 0.9 0.9 -1.3 -0.5 -0.1 0.1
Mouth/teeth dental problems: Mouth ulcers 0.7 1.0 4.1 0.9 2.0 -0.8 0.2 0.1 -1.4 -0.7 0.6
Medication for cholesterol 0.6 0.9 2.2 -1.4 0.0 -0.1 -0.7 -0.9 1.5 0.7 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 2.2 0.4 1.5 0.2 0.3 0.1 0.1 0.2 0.5
Back pain experienced in last month 1.2 1.7 3.6 1.5 -0.1 1.1 1.9 -0.4 -1.7 -0.5 1.8
Mineral and other dietary supplements 0.6 0.8 2.7 0.2 1.1 -1.2 0.3 -1.6 -0.4 0.7 0.2
Breast cancer (self-reported) 0.8 1.0 2.4 -0.9 0.2 1.3 -0.7 0.2 -0.5 1.6 -1.4
Asthma (self-reported) 0.2 0.4 0.7 0.6 -0.8 0.8 0.2 -0.5 -0.8 -0.1 -0.7
Osteoporosis (self-reported) 0.4 0.5 2.0 0.5 -0.8 0.2 -0.1 -0.8 0.7 -1.4 0.5
Osteoarthritis (self-reported) 0.3 0.4 1.0 -0.8 0.1 0.1 -0.2 1.0 0.1 1.0 -0.7
Medication: Aspirin 1.8 2.4 4.4 1.3 1.0 1.7 1.5 -2.1 -1.9 -1.1 1.3
Medication: Gliclazide 0.7 0.8 2.1 -0.1 1.4 1.2 0.5 0.1 -1.0 1.2 -0.3
Illnesses of father: None of the above (group 1) 0.3 0.4 1.0 0.5 0.4 0.2 1.0 -0.0 -1.0 -0.0 0.8
Smoking status: Current 1.7 2.7 10.4 1.3 3.2 0.8 0.9 0.5 -0.5 -1.0 2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 0.8 0.3 0.6 -0.6 -0.3 0.1 0.3 -0.9 0.4
Whole body water mass 0.8 4.5 11.2 2.5 3.3 -0.0 2.3 -0.5 -1.8 -1.3 2.8
Leg predicted mass (right) 0.6 3.1 11.8 1.9 3.4 -0.4 1.6 -0.7 -1.2 -0.8 2.0
Arm fat mass (left) 0.1 0.4 1.4 0.9 1.2 0.5 0.1 -0.6 -0.1 -0.5 0.3
Number of self-reported non-cancer illnesses 1.1 1.9 4.1 1.6 -0.8 2.0 1.2 -0.2 -1.0 -2.0 1.3
Average weekly champagne plus white wine intake 1.5 2.0 10.9 -0.2 -3.3 1.0 -1.3 -0.1 1.2 -0.9 -0.6
Miserableness 0.5 0.9 2.9 -0.3 -0.9 -0.7 -0.6 1.2 -0.2 1.7 -1.1
Guilty feelings 0.9 1.3 7.0 -0.6 -2.7 -1.3 -0.7 0.1 0.7 -0.1 -0.5
Wears glasses or contact lenses 0.3 0.4 1.5 -0.4 -0.2 -0.0 -1.1 1.2 0.4 -0.1 -0.1
Ever taken oral contraceptive pill 0.7 0.7 2.4 0.1 -1.4 1.5 0.6 0.7 -0.8 0.1 -0.0
Hearing aid user 0.6 0.7 1.2 -1.1 1.0 0.5 -0.9 0.9 0.9 -0.5 0.7
Mother’s age at death 1.0 1.3 3.0 1.1 -1.2 1.1 0.8 -0.8 -0.6 -1.2 1.7
Financial situation satisfaction 0.4 0.5 2.6 -0.5 0.3 -1.6 -0.1 -0.2 0.5 0.1 -0.7
Tinnitus: Yes, now most or all of the time 0.2 0.3 0.6 -0.5 0.8 -0.7 -0.3 0.5 -0.3 0.5 0.3
Commuting to job workplace: Public transport 1.2 1.4 7.5 0.6 0.1 2.7 0.7 -0.7 -1.2 -0.5 0.9
Eye problems/disorders: Glaucoma 0.3 0.3 1.0 0.3 -1.0 -0.7 -0.1 -0.3 -0.1 0.8 -0.7
Medication: Blood pressure 0.1 0.2 0.6 0.6 0.2 -0.1 0.3 0.5 -0.8 -0.1 0.3
Pain type(s) experienced in last month: Hip pain 0.3 0.3 1.0 0.1 0.2 -0.4 -0.4 0.8 -0.1 1.0 -0.9
Supplements: Fish oil (including cod liver oil) 0.7 0.9 3.3 -0.4 -1.1 0.7 -0.9 1.8 0.7 -0.5 -0.8
High cholesterol (Self-reported) 0.9 1.6 3.4 1.2 0.4 1.4 1.1 -1.2 -1.8 -0.8 1.4
Medication: Bendroflumethiazide 0.3 0.5 1.9 0.0 1.4 0.2 -0.2 0.3 -0.9 0.9 -0.3
Medication: Paracetamol 0.3 0.5 1.4 0.2 -1.2 0.8 -0.6 0.2 0.2 -1.2 -0.2
Medication: Lisinopril 1.0 1.3 4.1 -0.7 0.8 -1.5 -0.8 0.5 0.1 2.0 -1.4
Medication: Atorvastatin 1.8 2.3 4.6 2.1 -0.7 0.6 2.1 -1.5 -1.8 -0.5 1.6
Illnesses of father: High blood pressure 0.2 0.3 1.1 0.2 -1.1 0.1 0.6 0.2 -0.1 0.5 -0.4
Alcohol drinker status: Never 2.1 2.6 5.5 -2.1 0.4 -1.2 -1.8 0.6 1.2 2.3 -2.0
Ever smoked 0.9 1.6 4.6 1.3 1.3 0.2 0.7 1.8 -1.0 -0.1 2.1
Basal metabolic rate 0.6 3.5 11.2 2.2 3.3 -0.0 1.9 -0.5 -1.5 -0.9 2.2
Leg fat percentage (left) 0.1 0.4 0.9 0.0 -0.5 0.9 -0.7 -0.9 0.2 0.2 -0.9
Arm fat-free mass (left) 0.9 4.7 8.5 2.9 2.7 0.6 2.4 -1.0 -2.2 -1.7 2.7
Number of operations (self-reported) 1.3 1.9 4.5 -1.4 0.2 -0.9 -1.6 2.1 1.9 -1.4 0.4
Average weekly beer plus cider intake 1.6 2.3 11.8 -1.1 3.4 -1.5 -0.4 -0.1 1.5 0.6 -0.7
Irritability 0.7 1.2 3.5 1.5 -1.2 0.7 0.9 0.6 -1.9 0.1 0.7
Risk taking 2.0 2.9 8.2 2.0 1.3 -0.1 0.9 0.5 -0.8 -2.9 2.8
Ever had prostate specific antigen (PSA) test 1.7 2.0 5.4 -1.8 -0.1 -0.0 -2.3 1.7 1.5 -0.6 -1.3
Fractured/broken bones in last 5 years 1.5 1.9 6.5 0.5 0.5 2.2 0.9 -2.5 -1.6 0.2 -0.3
Age started oral contraceptive pill 2.4 3.0 5.9 -2.2 -0.5 -1.3 -2.4 2.2 2.2 0.2 -1.5
Diastolic blood pressure, automated reading 0.3 0.8 3.8 0.0 -1.9 1.3 0.1 -1.0 0.1 0.3 -0.6
Ever depressed for a whole week 0.6 0.8 3.1 -0.4 -0.1 0.2 -0.1 -1.2 -0.2 1.8 -1.2
Unable to work because of sickness or disability 0.2 0.3 0.8 -0.3 0.7 0.9 -0.1 -0.4 -0.0 0.2 -0.7
Commuting to job workplace: Cycle 1.5 1.9 4.4 -2.1 -0.4 -1.4 -1.0 1.4 1.7 1.1 -1.1
Myopia 0.2 0.3 0.7 0.2 0.4 0.6 0.1 0.1 -0.9 0.7 0.2
Vascular/heart problems diagnosed by doctor 0.9 2.4 5.3 -1.5 0.5 -1.6 -2.3 1.6 2.3 0.5 -0.7
Cholesterol lowering medication 0.7 1.1 2.4 0.7 -0.7 1.3 1.1 -1.2 -1.5 0.4 0.8
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 2.0 0.2 -1.4 -0.5 -0.2 0.4 0.3 -0.4 -0.3
Pain experienced in last month 0.3 0.5 1.3 -1.1 0.2 0.1 -0.9 -0.5 0.6 0.6 -0.8
Supplements: Calcium 0.3 0.3 1.5 0.1 0.1 0.4 -0.7 1.2 0.7 -0.3 -0.4
Basal cell carcinoma (self-reported) 1.1 1.3 1.9 1.0 0.8 1.2 1.4 -0.9 -1.4 -1.3 1.1
Heart attack/myocardial infarction (self-reported) 2.0 2.6 4.2 1.5 1.5 1.7 1.8 -1.2 -2.1 -1.5 1.6
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 4.8 0.9 2.2 0.6 0.5 -1.8 -0.4 -1.2 0.6
Heart disease (siblings) 0.6 0.7 3.7 -0.4 -1.9 0.9 0.3 -0.8 -0.2 -0.5 0.6
Alcohol drinker status: Previous 0.2 0.3 0.8 -0.3 0.3 -0.2 0.6 -0.2 0.9 0.7 -0.4
Pack years of smoking 2.0 3.0 5.4 2.3 2.2 0.9 2.1 -1.8 -1.9 -0.2 1.1
Impedance of whole body 0.5 2.6 5.4 -2.0 -0.6 -0.9 -1.4 1.3 1.4 2.3 -2.1
Leg fat mass (left) 0.1 0.2 0.7 0.5 0.8 0.3 0.0 -0.7 -0.1 0.2 -0.0
Arm predicted mass (left) 0.8 4.2 8.0 2.8 2.6 0.4 2.2 -0.8 -1.9 -1.5 2.8