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chr7:91,046,993-93,160,671

Best TWAS P=1.61e-12 · Best GWAS P=4.51e-13 conditioned to 0.000135

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CDK6	0.12	0.10	lasso	2	0.10	1.9e-12	-5.93	-5.9	2.9e-09	0.90	0.13	0.87	FALSE
2	GTEx	Adipose Visceral Omentum	GATAD1	0.12	0.08	lasso	5	0.06	7.5e-04	-4.94	5.3	9.7e-08	-0.53	0.38	0.56	FALSE
3	GTEx	Adrenal Gland	GATAD1	0.40	0.22	lasso	7	0.25	2.0e-09	-4.94	6.2	6.0e-10	-0.52	0.64	0.12	FALSE
4	GTEx	Artery Aorta	KRIT1	0.15	0.00	enet	24	0.03	1.3e-02	0.48	6.0	2.6e-09	-0.35	0.08	0.39	FALSE
5	GTEx	Artery Aorta	GATAD1	0.09	0.08	enet	4	0.07	7.4e-05	-4.94	5.3	1.4e-07	-0.48	0.53	0.04	FALSE
6	GTEx	Artery Coronary	GATAD1	0.12	0.15	lasso	3	0.12	8.0e-05	-5.06	5.3	1.5e-07	-0.48	0.17	0.26	FALSE
7	GTEx	Artery Tibial	AC000120.7	0.08	0.06	lasso	4	0.06	3.2e-05	-4.56	5.4	6.2e-08	-0.29	0.96	0.00	FALSE
8	GTEx	Brain Caudate basal ganglia	GATAD1	0.21	0.09	lasso	4	0.08	2.3e-03	-3.82	5.6	2.3e-08	-0.48	0.08	0.23	FALSE
9	GTEx	Brain Cortex	AC000120.7	0.12	0.08	enet	16	0.07	7.0e-03	-4.79	5.7	1.3e-08	-0.45	0.14	0.05	FALSE
10	GTEx	Cells Transformed fibroblasts	GATAD1	0.23	0.20	lasso	4	0.22	1.4e-16	-4.94	5.6	2.6e-08	-0.60	1.00	0.00	FALSE
11	GTEx	Colon Transverse	GATAD1	0.13	0.00	enet	16	0.05	3.0e-03	-4.94	7.0	3.6e-12	-0.44	0.21	0.12	FALSE
12	GTEx	Esophagus Mucosa	GATAD1	0.16	0.05	enet	16	0.08	7.3e-06	-4.94	5.7	1.2e-08	-0.51	0.73	0.15	FALSE
13	GTEx	Esophagus Muscularis	GATAD1	0.18	0.10	enet	33	0.13	1.6e-08	-4.94	6.3	2.9e-10	-0.40	0.97	0.01	FALSE
14	GTEx	Muscle Skeletal	GATAD1	0.05	0.00	enet	13	0.01	2.4e-02	-5.10	6.7	2.4e-11	-0.45	0.47	0.04	FALSE
15	GTEx	Skin Sun Exposed Lower leg	GATAD1	0.30	0.10	enet	14	0.16	7.0e-13	-4.94	6.1	9.7e-10	-0.45	1.00	0.00	FALSE
16	GTEx	Spleen	AC000120.7	0.10	0.07	lasso	5	0.04	3.9e-02	-4.54	5.2	2.1e-07	-0.22	0.15	0.06	FALSE
17	GTEx	Stomach	GATAD1	0.30	0.13	lasso	5	0.15	8.6e-08	-4.94	5.4	6.1e-08	-0.53	0.97	0.00	FALSE
18	GTEx	Testis	CDK6	0.10	0.10	lasso	3	0.09	8.0e-05	-5.59	6.8	8.6e-12	-0.84	0.08	0.86	FALSE
19	METSIM	Adipose	GATAD1	0.10	0.05	lasso	7	0.06	9.4e-10	-5.10	5.7	1.5e-08	-0.47	0.89	0.11	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	KRIT1	0.04	0.03	bslmm	311	0.01	9.0e-03	-4.53	-5.5	2.9e-08	0.44	0.77	0.02	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	GATAD1	0.17	0.15	lasso	4	0.16	6.0e-20	-5.04	5.3	9.2e-08	-0.49	1.00	0.00	FALSE
22	YFS	Blood	CYP51A1	0.03	0.06	blup	288	0.05	1.2e-16	-4.94	5.1	3.0e-07	-0.30	1.00	0.00	FALSE
23	YFS	Blood	GATAD1	0.01	0.01	blup	297	0.01	5.1e-04	-4.94	7.1	1.6e-12	-0.59	0.72	0.12	TRUE