Best TWAS P=4.62e-23 · Best GWAS P=1.54e-41 conditioned to 1.23e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CD36 | 0.06 | 0.04 | blup | 558 | 0.03 | 4.1e-05 | 13.3 | 7.5 | 5.2e-14 | 0.74 | 0.01 | 0.99 | TRUE |
| 2 | METSIM | Adipose | CD36 | 0.05 | 0.03 | lasso | 3 | 0.05 | 2.1e-07 | -2.6 | 6.2 | 4.8e-10 | 0.48 | 0.65 | 0.27 | FALSE |
| 3 | NTR | Blood | CD36 | 0.06 | 0.01 | blup | 456 | 0.03 | 2.5e-11 | 11.3 | -9.9 | 4.6e-23 | -0.43 | 0.97 | 0.02 | TRUE |
| 4 | YFS | Blood | CD36 | 0.37 | 0.28 | enet | 53 | 0.35 | 9.4e-122 | 5.2 | -9.0 | 3.3e-19 | -0.53 | 1.00 | 0.00 | FALSE |
| 5 | YFS | Blood | SEMA3C | 0.03 | 0.00 | bslmm | 511 | 0.01 | 3.6e-03 | 7.9 | 6.4 | 1.2e-10 | 0.13 | 0.05 | 0.03 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CD36 | 0.07 | 0.05 | lasso | 5 | 0.04 | 2.8e-05 | 8.0 | 6.2 | 5.3e-10 | 0.58 | 0.86 | 0.11 | FALSE |