Best TWAS P=2.26e-28 · Best GWAS P=6.76e-29 conditioned to 4.28e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellum | MAMDC2 | 0.25 | 0.05 | enet | 5 | 0.09 | 0.00109 | 7.2 | 7.4 | 1.8e-13 | 0.56 | 0.07 | 0.20 | FALSE |
2 | METSIM | Adipose | KLF9 | 0.05 | 0.00 | bslmm | 509 | 0.02 | 0.00098 | 9.1 | 5.7 | 1.6e-08 | 0.09 | 0.30 | 0.02 | FALSE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | KLF9 | 0.01 | 0.01 | blup | 37 | 0.01 | 0.01790 | -9.6 | 11.0 | 2.3e-28 | 0.73 | 0.01 | 0.90 | TRUE |
4 | The Cancer Genome Atlas | Thyroid Carcinoma | KLF9 | 0.04 | 0.01 | blup | 37 | 0.02 | 0.00989 | 9.0 | 10.9 | 8.3e-28 | 0.56 | 0.02 | 0.86 | FALSE |