Hub : Genes

MAMDC2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1860	0.0430	4.7e-13	0.029	0.132	0.132	0.114	0.091	1.8e-04	8.7e-16	9.8e-16	1e-13	3.8e-11
2	GTEx	Adipose Subcutaneous	0.0710	0.0360	9.2e-03	0.030	NA	0.021	NA	0.039	1.6e-03	NA	7.3e-03	NA	3.3e-04
3	GTEx	Artery Aorta	0.2320	0.0650	6.2e-05	0.107	NA	0.086	NA	0.095	1.8e-06	NA	1.9e-05	NA	6.3e-06
4	GTEx	Brain Cerebellum	0.2470	0.0830	1.3e-03	0.054	NA	0.093	NA	0.082	1.1e-02	NA	1.1e-03	NA	2.1e-03
5	GTEx	Nerve Tibial	0.0881	0.0365	2.7e-03	0.080	NA	0.056	NA	0.061	2.7e-06	NA	8.0e-05	NA	3.7e-05
6	GTEx	Ovary	0.3230	0.1220	2.8e-03	0.112	NA	0.019	NA	0.107	1.1e-03	NA	1.1e-01	NA	1.4e-03
7	TCGA	Brain Lower Grade Glioma	0.0183	0.0122	8.8e-03	0.008	0.012	0.016	NA	0.002	3.3e-02	1.6e-02	4.9e-03	NA	1.6e-01
8	TCGA	Lung Adenocarcinoma	0.0596	0.0314	1.5e-03	0.015	0.020	0.024	NA	0.022	6.5e-03	1.7e-03	7.1e-04	NA	1.2e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.1	1.8	7.9	2.0	0.3	2.8	0.1	-0.0	1.2	0.2	-0.6
Bipolar Disorder or Schizophrenia	1.4	3.3	9.3	1.6	1.1	2.9	-1.2	1.6	3.0	0.8	-0.8
Depressed Affect (Nagel 2018)	0.6	1.2	2.8	-0.2	1.0	1.1	-0.9	1.2	1.7	1.1	-1.1
Depression (Nagel 2018)	1.2	1.8	5.0	-1.0	1.1	0.8	-1.5	1.7	2.2	1.1	-0.5
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.4	-1.2	1.3	1.0	1.0	1.5	0.9	0.1	0.9
Neuroticism (Nagel 2018)	0.7	1.7	3.4	-0.8	1.6	1.8	0.5	1.8	1.4	-0.1	-1.3
Schizophrenia (2018)	1.2	2.5	8.7	0.4	1.2	1.4	-1.6	2.0	3.0	0.9	-0.5
Schizophrenia vs Biploar Disorder	0.8	1.1	5.3	-2.3	-0.3	-0.5	-0.9	0.6	1.0	0.6	0.7
Worry (Nagel 2018)	0.8	1.7	5.5	-1.2	1.3	2.3	1.6	1.2	0.3	-1.1	-0.3
Alzheimer’s Disease (in mother)	0.3	0.3	1.1	-0.5	-0.6	-1.0	-0.3	-0.4	0.4	0.1	0.5
Alzheimer’s Disease (in father)	0.6	0.7	4.2	0.0	-0.3	-0.8	0.1	0.2	2.0	0.6	0.5
Alzheimer’s Disease (including proxy)	0.5	0.7	3.4	-0.5	-0.5	-1.9	-0.4	-0.2	1.0	0.6	-0.3
Crohns Disease (2017)	0.4	0.9	2.0	0.5	0.7	0.2	-0.7	0.7	1.4	1.3	-1.4
Irritable Bowel Disease (IBD)	0.5	1.3	4.3	0.7	0.0	-0.7	-2.1	-0.1	1.7	1.5	-0.2
Ulcerative Colitis (UC)	0.8	1.5	4.9	0.4	-1.1	-1.2	-2.2	-1.2	0.8	0.4	1.3
Major Depression (MDD)	0.4	0.4	0.9	0.7	-0.7	1.0	0.6	-0.7	0.1	-0.9	0.1
Reaction Time	1.4	2.6	7.0	-0.3	2.6	2.1	-0.2	2.6	0.6	0.8	-1.3
Verbal and Numeric Reasoning (VNR)	0.7	1.7	3.2	-1.2	1.5	1.8	1.8	1.6	-0.3	-0.5	0.7
Breast Cancer	0.9	2.2	5.8	2.4	1.4	1.7	-1.7	1.0	-0.1	1.5	-0.9
Ovarian Cancer	0.4	0.5	2.4	0.9	0.6	1.6	-0.3	0.6	-0.0	0.4	0.1
Prostate Cancer	0.8	1.1	4.2	-2.0	-0.7	-0.2	-0.8	-0.2	0.6	0.7	1.6
Age at First Birth	1.8	2.6	8.9	-3.0	-1.5	-1.3	0.3	-1.2	0.2	-1.1	2.2
Bipolar Disorder (2011)	1.1	1.0	4.9	1.0	1.0	0.0	0.4	1.1	2.2	0.2	0.0
Body Mass Index (BMI) (2010)	0.3	0.5	1.7	0.3	-1.3	-0.2	-0.2	-1.0	0.6	-0.5	0.5
Coronary Artery Disease (CAD)	2.6	3.1	9.1	0.2	-2.3	-0.7	0.4	-2.3	-1.3	-3.0	1.5
Crohns Disease (2012)	0.9	1.4	4.7	0.6	0.4	0.4	-2.0	0.5	2.2	1.2	-0.5
Mean Putamen Volume	0.7	0.8	2.9	-0.9	-0.6	0.6	-1.7	-0.5	0.2	-0.8	1.0
Fasting Glucose	0.8	1.0	2.1	1.2	-1.1	-0.6	-0.7	-1.4	1.5	-0.5	0.2
HbA1C	0.9	1.0	3.1	0.1	-0.0	0.2	-1.6	0.7	1.7	1.1	1.0
HDL Cholesterol	0.5	0.9	2.7	-0.4	0.7	0.4	1.7	1.0	-0.1	-1.4	-0.8
LDL Cholesterol	0.6	1.0	3.1	0.2	0.0	1.6	-1.8	-0.1	0.5	1.4	0.5
Lupus	1.0	1.5	4.0	0.7	-2.0	-0.9	0.9	-1.9	-0.5	-1.0	0.9
Neuroticism (2016)	1.3	1.8	4.9	1.2	1.5	2.2	0.9	1.4	1.2	0.2	-1.3
Primary Biliary Cirrhosis	0.7	1.0	4.4	0.7	0.2	2.1	-0.5	0.5	0.9	0.9	0.9
Rheumatoid Arthritis	0.3	0.5	0.9	-0.5	-0.9	-0.4	0.9	-0.7	0.1	-0.9	0.6
Schizophrenia (2014)	1.8	4.1	13.2	0.1	1.1	1.9	-2.7	2.0	3.6	1.7	-0.4
Triglycerides	0.7	1.1	4.1	0.1	-0.9	0.6	-2.0	-1.1	0.1	1.2	0.8
Type 2 Diabetes (T2D) (2012)	1.2	1.4	3.0	0.6	-1.5	-0.7	-0.6	-1.4	1.7	-0.9	1.3
Ulcerative Colitis	1.2	1.7	5.6	1.7	-0.8	-0.3	-2.4	-1.1	1.4	0.5	0.8
Blood Eosinophil Count	0.1	0.5	0.9	0.2	-1.0	-0.6	0.6	-0.8	0.9	-0.7	0.8
Blood Platelet Count	1.1	12.8	54.2	0.8	-2.3	-3.7	7.4	-1.9	0.3	-5.0	0.3
Blood Red Count	0.1	1.1	4.7	0.3	-0.9	-2.2	-0.6	-1.2	0.1	-0.2	1.1
Blood White Count	0.7	5.5	10.2	0.6	-3.2	-2.9	2.0	-3.0	0.5	-2.9	1.9
Heel T-Score	0.2	1.8	3.5	1.6	-0.6	0.1	1.9	-0.5	1.8	-1.9	-1.0
BMI	0.4	2.6	8.9	-0.2	-2.3	-0.7	-1.4	-1.3	1.3	-0.8	3.0
Height	0.1	1.4	3.6	-1.9	1.4	1.4	0.2	1.1	0.4	0.2	1.4
Waist Hip Ratio (WHR)	0.4	1.7	6.2	1.1	0.2	2.5	0.2	-0.5	-2.2	-0.4	1.1
Systolic Blood Pressure	1.3	6.4	12.6	-2.0	-3.0	-0.2	2.0	-3.3	-2.2	-3.5	2.4
Smoking Status	0.3	0.7	1.8	0.4	-0.8	-1.3	-1.3	-0.7	-0.1	0.6	-0.5
Allergy or Eczema	0.5	1.2	2.8	1.6	1.7	0.6	-0.1	1.1	-0.7	1.3	-0.8
Cardiovascular Disease	0.7	2.3	7.0	-1.3	-1.1	-0.1	-2.4	-1.1	-0.2	-1.3	2.6
Hypothyroidism (self reported)	0.5	1.2	2.5	-1.4	1.2	0.9	1.6	1.2	-1.0	-0.7	-0.3
Respiratory disease	0.5	1.1	5.0	-0.1	-0.1	0.6	0.7	-0.7	-2.2	-0.7	1.3
Type 2 Diabetes (T2D) (2018)	0.7	1.4	3.1	-0.8	1.3	0.6	-1.8	1.6	-0.2	1.4	-0.7
Lung FEV1/FVC ratio	1.2	5.9	14.5	2.5	2.4	1.3	-0.8	2.8	2.9	1.4	-3.8
Lung FVC	2.1	10.6	20.0	-1.8	-4.2	-4.4	2.7	-4.5	-0.6	-2.8	3.0
Neuroticism	0.9	2.1	4.3	0.2	1.7	2.1	0.7	1.8	2.0	-0.3	-1.3
Chronotype (morning person)	4.6	10.6	19.1	-1.6	-3.4	-3.0	3.2	-3.9	-3.6	-4.4	1.9
Hair Pigment	0.0	1.2	4.3	2.1	-1.0	-1.7	0.3	-0.8	-0.7	0.0	-0.5
Tanning	0.0	0.5	1.3	0.2	0.6	-0.9	1.1	0.8	0.6	-0.2	-0.5
Hand grip strength (left)	0.6	1.5	4.8	2.1	0.4	-0.7	0.1	0.3	-1.5	0.3	-2.2
Number of treatments/medications taken	0.6	1.1	5.5	0.5	0.4	0.5	-2.4	0.3	0.8	1.3	-0.1
Average weekly spirits intake	0.2	0.2	0.7	-0.2	-0.9	0.3	-0.6	-0.6	-0.2	-0.2	-0.2
Sensitivity / hurt feelings	0.8	1.4	2.7	-1.3	1.0	0.7	-1.3	1.4	1.6	1.0	-1.0
Frequency of depressed mood in last 2 weeks	1.7	2.4	8.8	-1.1	0.5	0.7	-2.4	1.0	3.0	1.4	0.1
Hearing difficulty/problems: Yes	0.6	1.0	3.6	-0.3	0.3	1.9	-0.9	0.4	1.4	1.0	0.6
Relative age of first facial hair	0.8	1.7	3.3	1.5	1.3	0.1	1.8	1.6	1.5	0.4	-1.2
Other serious medical condition/disability diagnosed by doctor	4.3	5.6	13.5	0.4	2.5	2.8	-2.5	2.4	2.3	3.7	-0.1
Ever used hormone-replacement therapy (HRT)	1.4	1.8	7.3	-0.8	-0.6	-1.4	-2.7	-0.2	1.2	0.8	1.5
Ever had hysterectomy (womb removed)	0.8	0.9	2.4	-0.7	-1.5	-1.5	-0.1	-1.1	0.5	-0.9	0.6
Systolic blood pressure, automated reading	0.7	1.9	5.5	-0.6	-1.0	-0.0	1.7	-1.4	-1.8	-2.4	0.7
Eye problems/disorders: Diabetes related eye disease	1.2	1.4	4.5	-1.5	-0.4	1.2	-2.1	-0.0	0.5	-0.3	1.5
Angina	0.8	1.1	3.8	1.9	0.5	0.4	-1.0	0.6	1.0	1.1	-1.0
Medication for hormone replacement therapy	1.1	1.2	4.1	-0.7	-0.4	-0.9	-2.0	0.1	1.8	0.8	0.6
Vitamin and mineral supplements	0.6	0.8	1.2	1.0	-0.6	-0.1	1.0	-0.9	-0.9	-1.1	-1.1
Supplements: Zinc	0.2	0.2	0.4	0.0	0.6	0.3	0.6	0.7	0.1	0.6	0.5
Medication: Co-codamol	1.7	1.9	5.8	-0.4	-1.7	-0.3	0.9	-1.8	-0.6	-2.4	1.4
Medication: Metformin	0.8	1.2	1.7	-0.5	1.2	1.1	-1.3	1.3	-1.2	1.2	0.1
Diabetes (father)	0.2	0.3	0.8	0.1	0.8	-0.4	0.4	0.9	-0.1	-0.7	0.3
Diabetes (mother)	2.0	2.5	5.8	0.4	2.4	2.2	-1.4	1.7	-0.1	1.6	-1.2
Severe depression (siblings)	0.9	1.0	2.8	1.7	-0.9	-0.2	-0.8	-1.4	-0.8	-0.1	1.3
Pack years adult smoking proportion	0.4	0.6	2.2	1.5	0.4	1.1	0.2	0.3	-1.1	-0.1	-0.5
Impedance of leg (right)	0.2	1.2	2.8	-0.2	1.2	1.7	1.3	1.1	-0.5	-0.2	-1.3
Leg fat-free mass (left)	0.3	1.5	8.5	-0.7	-0.4	0.3	-1.3	0.2	1.1	0.2	2.9
Trunk fat percentage	0.5	2.2	11.0	-1.1	-0.9	1.6	0.3	-0.4	0.3	-1.2	3.3
Hand grip strength (right)	0.5	1.5	6.6	1.4	-0.3	-0.9	0.2	-0.5	-2.6	0.4	-1.4
Townsend deprivation index at recruitment	0.1	0.1	0.4	0.2	0.0	0.6	-0.3	-0.4	0.3	-0.4	0.3
Current tobacco smoking	0.2	0.4	0.9	-0.1	-0.6	-0.7	-0.1	-0.7	-0.8	-1.0	0.2
Average weekly fortified wine intake	0.4	0.5	1.4	-0.8	0.3	0.9	-0.2	0.3	0.3	1.0	1.2
Maternal smoking around birth	0.2	0.2	0.5	-0.6	-0.2	0.2	-0.7	0.2	-0.5	-0.7	-0.0
Fed-up feelings	0.5	1.0	3.7	-0.7	1.1	1.9	-0.2	0.8	1.2	0.4	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	5.6	-2.4	0.4	-0.6	-1.9	0.8	1.5	0.3	0.3
Relative age voice broke	2.3	3.6	7.2	1.3	1.8	-0.9	0.8	2.3	2.5	1.8	-2.7
Taking other prescription medications	0.4	0.6	1.5	-1.1	0.0	1.2	-1.0	-0.1	-1.0	-0.1	0.6
Age when periods started (menarche)	0.5	1.1	4.6	-0.9	0.1	0.1	1.7	0.3	2.1	0.3	0.6
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.3	-0.6	-0.5	-1.4	-0.5	-0.9	-0.7	-1.0	1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	1.7	1.3	0.6	0.7	1.2	0.6	0.4	-0.8	-1.3
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.8	-1.0	0.5	-0.1	-1.3	0.3	1.0	0.2	-0.4
Qualifications: CSEs or equivalent	1.0	1.4	5.9	0.6	-1.2	-2.4	-1.2	-1.3	0.1	0.2	-0.4
Serious illness, injury or assault to yourself	0.2	0.3	1.1	-1.1	-0.2	-0.2	-0.3	-0.2	0.8	0.4	0.2
High blood pressure	1.0	2.7	8.6	-1.0	-1.9	-0.4	-2.9	-1.9	-0.3	-1.2	1.7
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.5	0.7	1.1	0.9	0.8	0.7	-1.2	0.1	-0.0
Multivitamins +/- minerals	0.8	1.0	2.3	-1.5	0.8	-0.6	-1.0	1.1	1.2	0.8	0.8
Stomach or abdominal pain in last month	1.2	1.4	4.0	-0.8	0.6	0.1	-2.0	0.8	1.8	1.1	1.2
Supplements: Glucosamine	0.4	0.5	1.0	0.9	0.6	-0.1	0.5	0.7	1.0	0.9	0.3
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.0	-1.0	0.3	-0.5	-1.7	0.3	0.0	0.7	-0.5
Medication: Atenolol	0.1	0.2	0.8	0.6	-0.1	0.9	0.2	-0.0	0.2	-0.0	0.3
Medication: Levothyroxine sodium	0.2	0.4	1.4	-1.2	0.8	0.3	0.4	0.8	-0.2	0.2	-0.1
Sitting height	0.1	0.7	3.1	-1.1	0.0	-0.1	-0.4	0.4	0.4	0.7	1.8
Chronic bronchitis/emphysema (father)	0.7	0.9	3.7	-1.9	-0.1	0.2	-0.3	-0.3	-1.2	-0.3	1.3
High blood pressure (mother)	0.3	0.4	1.0	-1.0	0.9	0.0	-0.8	1.0	-0.3	0.2	-0.1
Body mass index (BMI)	0.4	1.8	9.7	-0.7	-1.4	0.2	-1.1	-0.8	0.1	-0.9	3.1
Impedance of leg (left)	0.2	0.9	2.7	-0.8	0.6	1.1	1.6	0.3	-0.9	-0.7	-1.1
Leg predicted mass (left)	0.3	1.6	9.1	-0.8	-0.4	0.3	-1.3	0.2	1.1	0.2	3.0
Trunk fat mass	0.6	2.4	13.5	-1.0	-0.9	1.4	-0.2	-0.3	0.4	-1.1	3.7
Waist circumference	1.2	4.3	22.0	-2.1	-1.2	1.2	-1.3	-0.8	-0.1	-1.5	4.7
Number of incorrect matches in round	0.5	0.8	3.7	-0.2	-1.1	0.3	0.2	-1.0	-0.3	-0.8	1.9
Past tobacco smoking	1.1	2.0	8.2	0.5	-0.6	0.2	2.9	-0.7	-0.7	-2.3	0.8
Alcohol usually taken with meals	0.4	0.7	1.5	-0.7	-0.6	-1.1	-0.5	-0.6	1.2	0.5	1.1
Nervous feelings	1.1	2.0	4.6	-0.8	2.0	1.5	0.1	2.1	1.8	0.6	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.7	-0.3	-0.4	0.2	-0.4	-0.4	0.9	-0.1	0.5
Hearing difficulty/problems with background noise	1.6	2.5	4.1	1.0	1.7	1.8	-1.6	1.5	2.0	2.0	-0.6
Hair/balding pattern: Pattern 2	1.1	1.3	3.0	0.7	-1.7	-1.5	-0.5	-1.7	0.4	-1.0	0.9
Had menopause	0.6	0.8	1.6	-1.1	-1.3	-1.2	-0.3	-0.8	1.0	-0.3	0.4
Had other major operations	0.4	0.4	2.2	0.1	-0.4	0.3	0.9	-0.3	-0.1	-1.5	-0.1
Forced vital capacity (FVC)	1.2	4.5	11.4	-1.4	-2.3	-3.4	2.5	-2.5	0.2	-1.4	1.7
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.6	1.4	1.2	0.6	0.9	1.3	0.8	0.2	-1.9
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	6.0	1.3	0.8	1.2	-0.7	0.5	-0.8	2.5	-1.1
Qualifications: None of the above	0.9	1.8	7.2	0.5	-1.6	-0.1	-1.2	-1.7	-2.7	-0.5	0.4
Financial difficulties in last 2 years	0.5	0.7	3.0	0.1	0.7	1.0	-0.5	0.4	-0.4	1.7	-0.4
Mouth/teeth dental problems	0.9	1.4	3.9	2.0	-1.1	-0.9	-1.1	-1.0	1.0	0.4	-1.2
Heart attack	0.4	0.5	1.1	-0.2	0.8	0.5	0.8	1.0	1.1	0.5	-0.2
Allergy	0.8	1.7	7.3	-1.0	-0.2	-0.9	-1.6	0.5	2.7	1.4	-0.4
Pain all over the body in last month	0.4	0.5	1.2	0.4	0.3	-1.0	-0.5	-0.1	-1.1	0.9	0.2
Diabetes (self-reported)	1.0	1.6	3.6	-0.4	1.4	0.8	-1.5	1.4	-0.5	1.9	-1.4
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	8.2	2.9	1.2	0.6	0.4	0.8	-0.2	1.1	-1.6
Medication: Ramipril	0.7	0.9	4.6	-0.9	0.8	-0.5	-2.1	0.8	0.3	0.3	-0.0
Medication: Simvastatin	1.3	1.9	8.1	-1.2	-1.0	0.3	-2.9	-0.8	-0.3	0.6	1.8
Fluid intelligence score	1.3	2.6	6.6	-1.2	1.8	2.1	1.3	2.6	1.8	-0.1	0.5
Illnesses of siblings	0.7	0.9	3.7	-0.5	-0.2	-0.7	-1.1	0.0	1.9	1.3	-0.2
Neuroticism score	0.4	0.9	2.6	-0.4	0.8	1.6	0.3	0.8	1.5	-0.5	-0.6
Weight	0.5	2.5	14.5	-1.4	-0.9	0.7	-1.0	-0.2	0.6	-0.8	3.8
Impedance of arm (right)	0.6	2.8	12.0	-1.0	1.6	1.3	3.5	1.3	0.4	-0.6	-1.8
Arm fat percentage (right)	0.3	1.2	5.9	-0.4	-0.6	1.2	0.3	-0.2	0.2	-1.3	2.4
Trunk fat-free mass	0.3	1.7	7.4	-0.8	-0.3	-0.4	-2.0	0.3	1.1	0.4	2.7
Hip circumference	0.7	3.1	16.1	-2.1	-1.3	0.3	-0.6	-0.6	0.7	-1.2	4.0
Time employed in main current job	0.8	0.9	1.6	1.0	1.3	1.3	-0.2	1.1	0.3	0.9	-1.0
Alcohol intake versus 10 years previously	0.7	1.1	2.0	0.9	1.4	1.2	1.2	1.1	-1.0	0.8	-0.4
Father’s age at death	0.2	0.2	0.7	-0.9	-0.2	0.1	-0.5	-0.1	0.3	-0.1	0.7
Worrier / anxious feelings	0.5	1.0	2.7	-1.6	0.9	1.4	0.7	1.0	0.8	-0.3	0.2
Frequency of tiredness / lethargy in last 2 weeks	2.5	4.1	8.4	-2.1	2.9	2.2	-1.7	2.6	1.0	1.6	1.6
Falls in the last year	0.5	0.7	2.4	-0.9	0.5	1.2	1.6	0.4	0.0	0.2	-0.6
Hair/balding pattern: Pattern 3	2.3	3.5	7.2	1.9	1.9	0.5	-0.9	2.1	1.7	2.2	-2.7
Number of live births	1.3	1.8	2.8	-1.7	-1.7	-1.6	0.5	-1.4	-1.5	-1.5	-0.1
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	6.5	-0.7	-1.1	-2.6	2.1	-1.3	1.0	-0.8	0.4
Pulse rate	0.4	0.6	1.7	0.3	-0.3	1.1	-0.7	-0.4	-1.1	-0.1	1.3
Happiness	2.6	3.1	9.8	-0.7	1.9	1.4	-2.4	1.3	0.8	3.1	0.8
Noisy workplace	1.3	1.6	4.3	2.1	1.1	1.2	-1.5	1.5	0.4	0.5	-1.2
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.5	1.1	0.9	1.9	1.2	0.7	1.1	-0.8	-0.2
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.1	-1.0	-1.5	-1.7	0.4	-1.7	-1.5	-0.8	-0.4
Mouth/teeth dental problems: Dentures	0.8	1.4	2.7	-1.6	-0.3	-0.0	1.7	-0.3	-1.1	-1.4	1.6
Asthma	0.7	1.4	6.0	-0.1	-0.3	0.8	1.1	-0.9	-2.4	-1.0	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	5.1	-0.3	-1.3	-2.3	-0.2	-1.2	0.8	-0.5	0.1
Medication: Cholesterol lowering	0.9	1.4	6.2	-0.3	-1.3	0.0	-2.5	-0.9	0.7	1.2	0.5
Depression (self-reported)	2.3	2.7	4.6	0.2	1.8	2.1	-2.0	1.8	0.9	2.2	1.1
Medication: Lansoprazole	0.4	0.4	1.3	-0.9	-0.2	0.1	0.1	-0.2	-0.5	-1.2	1.0
Prospective memory result	0.3	0.4	1.0	-0.8	-0.5	-0.3	0.1	-0.6	-0.6	-1.0	-0.4
Lung cancer (father)	1.1	1.3	2.8	-0.1	-0.7	1.7	0.7	-1.1	-1.2	-1.5	1.2
Illnesses of mother	0.4	0.5	1.7	0.1	-0.9	-0.3	1.3	-0.9	-0.0	-0.9	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	5.7	-0.7	-1.1	-2.4	1.6	-1.1	1.7	-0.5	0.9
Pulse wave Arterial Stiffness index	0.3	0.4	0.8	-0.1	0.8	0.9	-0.4	0.5	0.2	0.5	0.9
Impedance of arm (left)	0.4	1.8	8.7	-0.4	1.1	1.2	2.9	0.9	0.2	-0.3	-1.4
Arm fat mass (right)	0.4	1.8	10.3	-0.9	-1.0	0.5	-0.4	-0.5	0.3	-1.1	3.2
Trunk predicted mass	0.3	1.7	7.2	-0.8	-0.3	-0.3	-1.9	0.3	1.1	0.4	2.7
Standing height	0.1	1.1	3.0	-1.5	0.8	0.8	0.3	1.0	1.0	0.3	1.7
Length of working week for main job	1.0	1.1	2.1	-1.4	-1.3	0.4	0.3	-0.9	-0.6	-1.2	1.4
Exposure to tobacco smoke at home	2.6	2.9	7.2	-0.2	-2.1	-0.8	2.1	-1.9	-0.1	-2.7	1.6
Breastfed as a baby	0.4	0.5	2.2	-0.2	0.2	-0.6	-0.5	0.3	0.8	0.5	-1.5
Tense / ‘highly strung’	0.5	0.8	3.0	-1.1	-0.6	-0.1	1.1	-0.5	0.5	-1.7	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	5.5	-0.2	-0.0	2.4	-0.4	0.1	0.7	0.3	1.5
Hair/balding pattern: Pattern 4	0.4	1.0	2.4	-0.1	0.9	0.7	-1.5	1.2	-0.4	1.6	-0.5
Birth weight of first child	1.0	1.8	6.3	-0.8	-0.7	0.6	-1.9	-0.9	-0.8	1.1	2.5
Peak expiratory flow (PEF)	1.2	2.9	12.8	-0.6	-1.7	-3.6	1.1	-1.6	1.1	-1.4	-0.2
Pulse wave reflection index	0.9	1.1	2.9	0.5	1.1	0.8	-0.1	1.0	1.3	1.7	-0.9
Ever highly irritable/argumentative for 2 days	0.7	0.8	3.8	1.0	0.3	1.9	0.8	-0.2	-0.9	-0.4	0.1
Loud music exposure frequency	1.6	1.8	5.1	-0.3	1.2	0.7	-1.7	1.3	1.3	2.3	-1.1
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	4.9	1.6	2.2	0.8	1.0	2.2	1.9	-0.0	-0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.4	-1.1	1.2	0.8	0.6	1.0	-0.3	0.3	0.2
Blood clot in the leg (DVT)	0.9	1.2	2.8	-0.4	-1.0	-1.7	-0.1	-1.3	-0.8	-1.6	0.8
Medication: Paracetamol	0.2	0.3	1.2	-0.0	-0.5	0.0	1.1	-0.1	0.4	-0.4	1.0
Headache pain in last month	0.6	1.0	3.5	-0.5	1.0	-0.1	0.3	1.6	1.9	0.4	-0.7
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	3.8	0.6	0.8	-0.4	2.0	0.5	-0.9	-0.7	-1.5
Glaucoma (self-reported)	0.3	0.4	1.0	0.2	0.2	-0.8	-0.9	0.2	-0.3	1.0	-0.7
Gout (self-reported)	0.7	1.0	3.3	-0.9	-0.1	0.9	1.3	-0.1	-1.8	-1.0	-0.5
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.9	-0.8	0.7	0.4	1.4	0.4	-0.9	-0.8	-0.5
Medication: Amlodipine	1.4	1.9	6.5	-0.9	-1.7	-0.2	-1.2	-1.4	-0.6	-1.1	2.6
Medication: Ventolin 100micrograms inhaler	1.5	2.0	4.5	-1.2	-0.0	1.5	1.3	-0.3	-1.7	-1.7	2.1
Birth weight	0.7	1.5	3.0	-0.6	1.7	0.6	-1.2	1.4	-0.0	1.5	1.6
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.2	0.8	0.2	0.4	-1.5	0.3	0.4	1.4	-0.4
High blood pressure (siblings)	0.4	0.5	3.0	-0.1	0.6	0.7	-0.2	0.3	-1.7	-0.0	-0.4
Forced vital capacity (FVC), Best measure	0.8	3.0	7.0	-1.3	-1.7	-2.6	2.0	-1.8	0.6	-0.9	1.8
Body fat percentage	0.5	2.1	10.4	-0.7	-0.8	1.8	0.1	-0.4	-0.2	-1.4	3.2
Leg fat percentage (right)	0.5	1.9	8.1	-0.2	-0.4	2.1	-0.5	0.2	-0.4	-1.4	2.9
Arm fat-free mass (right)	0.5	2.6	13.4	-0.8	-1.2	-0.2	-2.1	-0.7	0.5	0.0	3.7
Exposure to tobacco smoke outside home	0.6	0.8	2.8	0.3	-1.3	-0.4	-1.1	-0.9	0.2	-0.1	1.7
Comparative body size at age 10	0.2	0.5	1.3	0.8	-0.2	-1.1	0.7	-0.2	0.7	-0.8	0.1
Number of full brothers	1.2	1.5	3.9	1.2	1.5	0.4	-0.8	1.1	-1.1	2.0	-1.0
Worry too long after embarrassment	1.0	1.7	4.5	0.6	2.1	1.6	0.5	1.7	0.8	0.1	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	3.0	-0.1	0.1	1.7	-0.7	0.2	1.7	0.0	1.3
Wheeze or whistling in the chest in last year	1.3	2.4	7.5	-1.3	-0.9	0.6	-0.5	-1.5	-2.7	-1.3	2.1
Number of children fathered	0.2	0.2	0.6	0.3	-0.8	0.2	-0.3	-0.4	-0.0	0.0	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.4	-0.6	-0.6	-1.2	-0.4	-0.2	0.8	0.1	0.0
Age at first live birth	0.5	0.9	2.1	-1.0	-0.6	-1.3	1.5	-0.6	1.1	-0.4	0.7
Pulse wave peak to peak time	0.3	0.3	0.9	-0.1	-0.7	-0.9	0.5	-0.4	-0.1	-0.5	-0.6
Health satisfaction	1.7	2.2	5.0	-2.2	1.4	1.8	-0.6	1.2	0.9	0.7	2.1
Shortness of breath walking on level ground	0.8	0.9	5.2	-0.8	-0.4	-0.1	-0.7	0.0	0.3	-0.8	2.3
Qualifications: College or University degree	0.8	2.4	4.7	0.5	1.9	1.8	1.8	1.8	2.2	0.2	-0.1
Eye problems/disorders: None of the above	1.6	1.8	4.5	1.2	0.6	0.9	1.9	-0.0	-2.1	-0.8	-1.7
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.9	-0.5	1.4	0.8	-1.7	1.2	-0.0	1.5	-0.2
Emphysema/chronic bronchitis	0.8	1.0	3.2	0.1	1.2	0.9	1.1	0.9	-1.8	0.4	-0.2
Medication for pain relief, constipation, heartburn	0.2	0.4	2.3	0.5	0.2	0.0	1.5	0.1	-0.1	-0.3	-0.8
Neck or shoulder pain in last month	0.9	1.2	3.4	-0.5	1.3	1.1	-1.8	1.1	0.2	1.4	-0.4
Medication: Blood pressure	0.7	1.2	5.7	-0.4	-0.7	0.1	-2.4	-0.4	1.2	0.5	1.0
Angina (self-reported)	0.9	1.2	3.9	2.0	0.6	0.3	-0.8	0.6	0.9	1.3	-1.3
Migraine (self-reported)	1.1	1.3	5.2	1.3	0.9	-0.2	-0.8	1.0	2.3	1.1	0.2
Medication: Ibuprofen	0.3	0.4	1.5	0.2	-0.5	-1.2	0.1	-0.6	0.6	-0.6	-0.2
Medication: Allopurinol	0.4	0.5	1.0	-0.5	-1.0	0.5	0.7	-0.8	-0.7	-0.8	0.1
Medication: Omeprazole	1.4	1.7	8.6	-0.7	-0.6	1.4	-1.4	-0.4	0.2	0.3	2.9
Medication: Seretide 50 evohaler	2.0	2.3	3.4	-0.3	-1.8	-1.9	1.6	-1.8	-1.7	-0.9	1.4
Mean time to correctly identify matches	1.8	3.4	8.3	-0.5	2.7	2.3	-1.3	2.9	1.5	1.2	-0.8
Heart disease (mother)	0.4	0.5	1.0	0.9	0.5	-1.0	-0.2	0.4	0.8	0.3	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.5	0.9	0.0	-1.6	-1.0	-0.1	-0.0	0.8	-1.2
Whole body fat mass	0.6	2.5	14.6	-1.0	-1.0	1.5	-0.2	-0.4	-0.0	-1.1	3.8
Leg fat mass (right)	0.5	2.1	12.0	-0.6	-0.6	1.5	-1.0	0.2	-0.0	-1.1	3.5
Arm predicted mass (right)	0.5	2.6	13.1	-1.1	-1.0	0.0	-2.2	-0.5	0.3	0.1	3.6
Pulse rate, automated reading	0.8	2.6	8.1	-1.1	-0.8	1.4	0.6	-1.1	-2.3	-1.5	2.8
Alcohol intake frequency.	0.2	0.6	2.1	-0.3	-0.2	0.4	0.8	-0.2	-0.6	-1.1	1.4
Comparative height size at age 10	0.4	2.1	5.7	-2.4	-1.5	-1.1	0.0	-1.1	0.2	-0.9	2.3
Number of full sisters	0.9	1.1	2.7	0.3	1.5	1.3	-0.2	1.2	-1.6	-0.6	-0.5
Suffer from ‘nerves’	1.3	2.1	3.6	-1.1	1.8	1.9	-1.5	1.6	1.2	1.5	-0.2
Overall health rating	1.1	2.4	6.6	-0.5	1.3	2.6	0.4	0.6	-2.4	-0.6	2.0
Chest pain or discomfort	0.4	0.5	1.9	-0.6	0.5	-0.1	-0.2	-0.2	-1.4	-1.0	-0.7
Had major operations	0.9	1.1	5.1	-2.2	-0.6	-0.1	0.1	-0.4	0.9	-0.9	1.2
Age at last live birth	0.4	0.6	1.5	-0.9	-0.3	-0.9	1.2	0.0	1.2	0.1	0.2
Family relationship satisfaction	3.1	3.8	6.6	0.2	2.4	2.0	-2.5	2.1	1.5	2.6	-1.2
Leg pain on walking	0.4	0.5	1.7	0.5	-0.5	-0.4	-0.5	-0.5	1.3	0.3	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.0	-0.7	0.1	0.7	-1.0	0.2	-0.4	0.8	-0.5
Commuting to job workplace: Car/motor vehicle	1.4	1.6	4.1	1.0	1.8	-0.4	1.7	2.0	1.0	0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	1.7	-0.8	0.3	1.3	0.9	0.8	1.3	-0.7	1.2
Medication: Aspirin	0.2	0.3	1.7	0.5	-0.2	0.1	-1.3	-0.0	0.4	-0.1	-0.4
Supplements: Vitamin C	0.7	0.9	2.7	1.2	0.0	1.6	-0.1	-0.3	-0.1	0.6	1.5
Knee pain experienced in last month	0.8	1.2	2.5	-0.2	-1.4	-0.1	0.4	-1.1	1.3	-1.4	1.6
Hypertension (Self-reported)	0.9	2.4	9.1	-1.2	-1.5	-0.1	-3.0	-1.6	-0.2	-1.1	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	4.9	-1.1	-0.5	0.7	-0.1	-0.7	0.3	-0.9	2.2
Illnesses of father: Heart disease	1.1	1.5	4.1	-0.8	0.7	-1.2	-1.8	1.1	2.0	0.7	0.9
Illnesses of siblings: Diabetes	0.9	1.1	3.1	0.5	0.5	1.4	1.1	0.1	-0.4	-1.2	1.8
Smoking status: Previous	1.1	1.6	4.4	-0.1	0.9	-0.0	-2.0	1.1	0.8	2.1	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.7	-0.2	1.2	-0.6	-0.1	1.3	0.1	0.3	-0.5
Whole body fat-free mass	0.3	2.0	9.3	-1.0	-0.5	-0.2	-1.9	0.1	1.2	0.4	3.1
Leg fat-free mass (right)	0.3	1.6	8.3	-0.9	-0.6	-0.2	-1.3	-0.1	1.1	0.2	2.9
Arm fat percentage (left)	0.3	1.4	7.6	-0.2	-0.7	1.1	0.2	-0.3	-0.1	-1.1	2.8
Average weekly red wine intake	0.3	0.4	1.5	-1.0	-0.2	-1.2	-0.8	-0.3	-0.1	0.1	0.1
Handedness (chirality/laterality): Left-handed	1.1	1.3	4.0	-0.9	-0.3	1.1	1.6	-0.6	-0.5	-1.3	2.0
Mood swings	0.1	0.3	1.5	0.4	-0.0	-0.4	0.4	0.0	0.2	0.0	-1.2
Loneliness, isolation	1.7	2.3	4.5	0.1	1.9	1.5	-2.1	1.8	1.6	1.5	-0.6
Long-standing illness, disability or infirmity	2.2	3.4	14.8	0.3	2.4	3.8	-0.9	2.0	0.1	1.0	0.4
Ever had bowel cancer screening	2.1	2.4	8.3	0.8	0.7	0.3	-2.9	1.0	2.1	1.9	-0.9
Diabetes diagnosed by doctor	0.9	1.5	3.4	-1.5	1.1	0.7	-1.8	1.0	-1.5	1.1	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.8	0.6	0.7	-0.8	-1.3	0.4	0.9	0.9	-0.5
Friendships satisfaction	0.8	1.0	2.2	1.0	1.5	1.3	-0.3	1.1	-0.3	1.0	-0.7
Qualifications: nursing, teaching	1.6	2.4	7.7	0.1	1.4	2.6	0.3	1.8	2.8	0.3	-0.4
Commuting to job workplace: Walk	0.4	0.4	1.8	0.1	0.2	1.4	0.1	-0.3	-0.7	-0.9	0.5
Eye problems/disorders: Cataract	1.0	1.2	3.9	-0.9	-1.2	-0.5	-0.3	-0.6	2.0	-0.4	1.6
Mouth/teeth dental problems: Mouth ulcers	2.2	3.6	6.7	-1.6	-2.0	-1.3	1.4	-2.1	-1.4	-2.6	2.3
Medication for cholesterol	0.9	1.4	5.1	0.6	1.2	-0.1	2.3	0.9	-0.1	1.2	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	3.4	-0.1	0.8	0.9	-1.8	0.4	-0.4	1.8	0.2
Back pain experienced in last month	0.2	0.3	0.8	0.0	0.5	0.3	0.8	0.3	0.1	0.4	0.9
Mineral and other dietary supplements	0.4	0.5	1.7	0.2	-1.3	-1.0	-0.0	-1.0	0.1	-0.3	-0.2
Breast cancer (self-reported)	2.5	3.0	8.9	1.1	3.0	2.1	1.2	2.3	-0.6	1.1	-0.9
Asthma (self-reported)	0.9	1.8	7.1	-0.3	-0.5	0.7	1.0	-1.2	-2.7	-1.4	1.5
Osteoporosis (self-reported)	0.3	0.4	1.6	-0.0	0.7	0.0	-0.7	0.5	0.2	1.3	-0.2
Osteoarthritis (self-reported)	1.2	1.5	5.2	0.3	0.3	2.3	-2.2	0.5	-0.0	0.4	1.2
Medication: Aspirin	0.2	0.3	1.2	1.1	0.1	0.3	-0.7	0.1	0.0	0.1	-0.5
Medication: Gliclazide	1.3	1.4	4.0	1.0	1.5	0.2	-2.0	1.5	0.5	1.2	-0.6
Illnesses of father: None of the above (group 1)	0.5	0.6	1.3	-0.2	-1.1	0.4	0.7	-1.0	-0.9	-0.1	-0.8
Smoking status: Current	0.3	0.5	1.0	-0.2	-0.8	-0.7	-0.2	-0.8	-0.7	-1.0	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.4	7.1	18.2	-0.4	-3.4	-4.3	2.7	-3.4	0.4	-2.7	1.2
Whole body water mass	0.3	1.9	8.8	-0.9	-0.5	-0.1	-1.8	0.1	1.2	0.4	3.0
Leg predicted mass (right)	0.3	1.6	8.4	-0.9	-0.6	-0.1	-1.3	-0.1	1.1	0.2	2.9
Arm fat mass (left)	0.5	2.0	11.7	-0.5	-1.2	0.8	-0.2	-0.7	-0.2	-1.1	3.4
Number of self-reported non-cancer illnesses	0.9	1.5	7.2	-0.9	-0.2	0.2	-2.7	-0.5	-0.5	0.1	1.8
Average weekly champagne plus white wine intake	2.1	2.9	6.1	-1.2	-2.5	-1.9	0.2	-2.3	0.6	-1.7	1.7
Miserableness	0.9	1.6	6.1	-0.4	1.0	0.1	-1.3	1.1	2.5	1.1	-1.2
Guilty feelings	1.2	1.7	6.4	1.3	-0.3	0.8	2.5	-0.7	-0.9	-1.9	-0.4
Wears glasses or contact lenses	1.1	1.3	5.9	1.9	0.1	2.4	0.6	-0.2	0.1	-0.6	-0.3
Ever taken oral contraceptive pill	0.7	0.8	2.8	0.8	-0.6	-1.7	1.1	-0.5	0.8	0.4	0.5
Hearing aid user	0.4	0.4	1.3	-0.7	0.7	-0.4	0.2	0.6	0.9	0.1	-1.2
Mother’s age at death	0.6	0.8	2.3	-0.1	1.5	-0.0	-0.0	1.5	-0.0	1.4	-0.1
Financial situation satisfaction	1.2	1.4	3.1	-0.2	1.8	1.7	-1.1	1.1	-1.0	1.1	0.8
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.7	-0.5	-0.8	-0.7	1.3	-0.5	0.6	-0.9	1.0
Commuting to job workplace: Public transport	0.5	0.6	3.4	-0.1	-0.2	1.9	-0.7	-0.6	0.3	-0.3	0.1
Eye problems/disorders: Glaucoma	0.7	0.9	2.4	0.6	-0.2	-1.2	-1.3	-0.0	0.3	1.5	-1.0
Medication: Blood pressure	0.5	0.9	1.8	0.2	-0.4	1.3	-1.3	-0.3	-1.0	-1.3	0.9
Pain type(s) experienced in last month: Hip pain	1.1	1.4	6.1	-0.7	1.2	2.5	-0.5	0.8	-1.2	-0.4	-0.9
Supplements: Fish oil (including cod liver oil)	1.2	1.6	3.9	0.6	2.0	1.4	-0.2	1.7	0.8	1.2	-1.3
High cholesterol (Self-reported)	0.9	1.5	4.4	-0.6	-1.5	-0.9	-2.1	-1.4	-0.6	0.2	1.5
Medication: Bendroflumethiazide	0.3	0.5	1.0	-1.0	-0.8	0.4	-0.5	-1.0	-1.0	0.1	-0.2
Medication: Paracetamol	0.3	0.4	2.4	0.6	-0.1	0.7	1.6	0.0	0.0	-0.5	0.2
Medication: Lisinopril	0.5	0.7	3.8	-0.4	-0.1	0.2	1.1	-0.1	-2.0	-0.6	-0.2
Medication: Atorvastatin	1.1	1.3	3.2	0.7	-1.5	-1.5	0.9	-1.8	-0.9	-0.8	-0.3
Illnesses of father: High blood pressure	1.0	1.3	4.8	0.7	2.2	1.1	-0.1	1.6	-0.8	0.4	-0.4
Alcohol drinker status: Never	1.0	1.2	4.5	0.8	0.4	2.1	0.3	0.8	1.7	0.5	-0.3
Ever smoked	1.0	1.8	9.2	-0.4	0.1	-0.4	-3.0	0.1	0.8	2.0	-0.3
Basal metabolic rate	0.4	2.1	11.1	-1.1	-0.6	0.1	-1.8	0.1	1.2	0.1	3.3
Leg fat percentage (left)	0.5	1.8	8.3	-0.4	-0.8	1.6	-0.5	-0.3	-0.7	-1.4	2.9
Arm fat-free mass (left)	0.4	2.3	11.4	-1.1	-0.9	-0.0	-2.1	-0.3	0.6	-0.0	3.4
Number of operations (self-reported)	0.8	1.2	5.3	-1.1	-0.5	-0.3	0.2	0.1	2.3	-1.4	1.0
Average weekly beer plus cider intake	0.4	0.6	1.3	-1.1	1.1	-1.0	0.0	0.8	-0.4	0.3	0.3
Irritability	1.0	1.7	4.1	0.2	1.0	1.8	1.4	1.3	2.0	-1.3	0.6
Risk taking	0.5	0.7	1.5	0.2	-0.9	-1.2	-1.1	-1.0	0.2	-0.6	0.9
Ever had prostate specific antigen (PSA) test	1.6	1.9	5.4	-1.1	1.0	0.1	-0.6	1.3	2.3	1.5	-1.6
Fractured/broken bones in last 5 years	1.5	2.0	4.6	-2.1	-1.3	-0.8	-1.8	-1.5	-1.0	-1.1	1.2
Age started oral contraceptive pill	0.3	0.4	1.3	0.0	-0.2	-0.2	1.0	-0.2	-0.8	-1.1	0.6
Diastolic blood pressure, automated reading	0.2	0.7	2.4	-0.2	0.2	1.6	0.0	-0.4	-1.5	-0.3	0.8
Ever depressed for a whole week	1.5	1.8	6.3	1.9	-0.7	0.7	-1.1	-0.6	1.0	2.5	1.1
Unable to work because of sickness or disability	0.1	0.1	0.5	-0.1	-0.4	-0.1	-0.0	-0.5	-0.7	-0.3	0.2
Commuting to job workplace: Cycle	0.5	0.6	1.4	-1.0	-0.4	-0.0	1.2	-0.5	-1.1	-1.0	-0.3
Myopia	1.9	2.8	8.7	-1.2	2.3	3.0	-0.3	2.4	0.1	0.1	-1.0
Vascular/heart problems diagnosed by doctor	0.7	1.9	9.1	0.6	1.4	0.0	3.0	1.4	-0.2	0.7	-1.2
Cholesterol lowering medication	1.0	1.5	3.9	-0.8	-1.0	0.3	-0.5	-1.2	-1.4	-1.5	2.0
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	5.5	-1.0	0.2	1.6	-2.3	0.3	0.6	1.0	2.2
Pain experienced in last month	0.4	0.6	1.9	1.1	-0.5	0.5	-0.4	-1.0	-1.4	-0.4	-0.6
Supplements: Calcium	0.2	0.2	1.1	-0.1	-0.1	-1.1	-0.2	-0.1	0.7	-0.1	0.3
Basal cell carcinoma (self-reported)	0.2	0.3	0.8	0.3	-0.9	-0.6	0.2	-0.8	-0.3	-0.4	0.2
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.2	-0.1	0.7	0.7	1.1	0.9	1.1	0.4	-0.3
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	3.5	-0.5	-0.9	-1.9	0.2	-1.2	-0.4	-1.6	1.0
Heart disease (siblings)	0.1	0.2	0.7	0.3	0.0	0.5	-0.3	0.4	-0.3	-0.8	0.2
Alcohol drinker status: Previous	0.3	0.4	1.4	0.1	-0.7	0.2	0.0	-0.8	-0.4	-0.6	1.2
Pack years of smoking	0.5	0.7	2.6	1.6	0.6	1.1	0.0	0.5	-1.0	-0.1	-0.4
Impedance of whole body	0.3	1.6	6.3	-0.5	1.2	1.5	2.5	0.9	-0.4	-0.4	-1.3
Leg fat mass (left)	0.6	2.2	13.0	-0.8	-0.8	1.3	-0.9	-0.0	-0.1	-1.0	3.6
Arm predicted mass (left)	0.4	2.1	9.7	-1.1	-0.7	0.3	-2.1	-0.2	0.7	0.1	3.1