Best TWAS P=2.14e-22 · Best GWAS P=1.41e-23 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KIAA1462 | 0.23 | 0.11 | lasso | 5 | 0.14 | 4.4e-08 | -6.6 | 7.4 | 1.5e-13 | -0.29 | 0.88 | 0.08 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | KIAA1462 | 0.36 | 0.26 | lasso | 6 | 0.25 | 1.6e-18 | -9.7 | -9.7 | 2.1e-22 | 0.97 | 0.04 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | KIAA1462 | 0.15 | 0.02 | blup | 112 | 0.02 | 4.8e-02 | -6.9 | 8.4 | 4.5e-17 | -0.69 | 0.01 | 0.63 | FALSE |