TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood Platelet Count
:
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chr10:43,686,552-44,318,235
Best TWAS P=2.85e-10 · Best GWAS P=1.84e-10 conditioned to 1
43.7M
43.8M
43.9M
44M
44.1M
44.2M
44.3M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
ZNF487
0.04
0.01
lasso
3
0.01
1.0e-02
-6.3
-6.3
2.8e-10
1.0
0
0.98
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
ZNF487
0.11
0.03
lasso
4
0.05
1.2e-05
-6.4
-5.5
3.2e-08
0.9
0
1.00
FALSE
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
ZNF239
0.02
0.00
enet
8
0.00
5.2e-02
2.1
5.3
8.8e-08
-0.5
0
0.07
FALSE