Best TWAS P=2.85e-10 · Best GWAS P=1.84e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZNF239 | 0.02 | 0.00 | enet | 8 | 0.00 | 5.2e-02 | 2.1 | 5.3 | 8.8e-08 | -0.5 | 0 | 0.07 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF487 | 0.04 | 0.01 | lasso | 3 | 0.01 | 1.0e-02 | -6.3 | -6.3 | 2.8e-10 | 1.0 | 0 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZNF487 | 0.11 | 0.03 | lasso | 4 | 0.05 | 1.2e-05 | -6.4 | -5.5 | 3.2e-08 | 0.9 | 0 | 1.00 | FALSE |