TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
:
Blood Platelet Count
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chr10:80,443,273-81,901,722
Best TWAS P=2.38e-21 · Best GWAS P=2.18e-21 conditioned to 0.000138
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
ZCCHC24
0.12
0.01
lasso
6
0.03
3.4e-03
-9.2
-9.5
2.4e-21
0.80
0.01
0.97
TRUE
2
GTEx
Skin Sun Exposed Lower leg
ZCCHC24
0.09
0.00
enet
18
0.00
2.3e-01
1.7
-9.2
2.7e-20
0.39
0.02
0.65
TRUE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ZCCHC24
0.07
0.05
enet
9
0.04
6.7e-05
-9.0
-9.2
2.7e-20
0.84
0.05
0.95
FALSE
3
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
ZCCHC24
0.06
0.00
blup
89
0.01
6.2e-02
-4.8
-8.2
3.0e-16
0.48
0.01
0.19
FALSE