Best TWAS P=2.38e-21 · Best GWAS P=2.18e-21 conditioned to 0.000138
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZCCHC24 | 0.12 | 0.01 | lasso | 6 | 0.03 | 3.4e-03 | -9.2 | -9.5 | 2.4e-21 | 0.80 | 0.01 | 0.97 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ZCCHC24 | 0.09 | 0.00 | enet | 18 | 0.00 | 2.3e-01 | 1.7 | -9.2 | 2.7e-20 | 0.39 | 0.02 | 0.65 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ZCCHC24 | 0.06 | 0.00 | blup | 89 | 0.01 | 6.2e-02 | -4.8 | -8.2 | 3.0e-16 | 0.48 | 0.01 | 0.19 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZCCHC24 | 0.07 | 0.05 | enet | 9 | 0.04 | 6.7e-05 | -9.0 | -9.2 | 2.7e-20 | 0.84 | 0.05 | 0.95 | FALSE |