Best TWAS P=6.13e-10 · Best GWAS P=6.75e-18 conditioned to 4.08e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PTEN | 0.07 | 0.00 | blup | 450 | 0.01 | 0.0599 | 7.4 | -6.2 | 7.2e-10 | -0.38 | 0.20 | 0.32 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ATAD1 | 0.06 | 0.03 | enet | 11 | 0.02 | 0.0028 | 5.1 | -6.2 | 6.1e-10 | -0.26 | 0.04 | 0.38 | TRUE |