Best TWAS P=8.96e-16 · Best GWAS P=1.14e-36 conditioned to 2.75e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | RP11-218M22.1 | 0.30 | 0.22 | enet | 27 | 0.22 | 2.7e-20 | 4.8 | 6.4 | 1.2e-10 | 0.52 | 1.00 | 0.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NINJ2 | 0.10 | 0.01 | lasso | 6 | 0.02 | 1.6e-03 | -3.3 | 8.0 | 9.0e-16 | 0.36 | 0.10 | 0.51 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | NINJ2 | 0.09 | 0.01 | blup | 114 | 0.05 | 2.2e-06 | -8.3 | -8.0 | 1.7e-15 | -0.40 | 0.42 | 0.29 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | NINJ2 | 0.05 | 0.04 | lasso | 3 | 0.03 | 3.4e-04 | 4.6 | 5.4 | 5.9e-08 | 0.54 | 0.12 | 0.73 | FALSE |