Best TWAS P=1.28e-16 · Best GWAS P=4.3e-18 conditioned to 0.977
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 | GTEx | Testis | DDHD1 | 0.17 | 0.09 | lasso | 5 | 0.15 | 2.6e-07 | -8.5 | -8.3 | 1.3e-16 | 0.93 | 0.02 | 0.98 | TRUE |
| 3 | GTEx | Brain Cortex | TXNDC16 | 0.26 | 0.08 | lasso | 6 | 0.03 | 4.2e-02 | -4.2 | 5.4 | 5.9e-08 | -0.17 | 0.09 | 0.06 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DDHD1 | 0.05 | 0.04 | blup | 68 | 0.04 | 4.9e-05 | -8.4 | 7.8 | 5.5e-15 | -0.95 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Brain Cerebellum | RP11-368P15.3 | 0.13 | 0.07 | enet | 7 | 0.05 | 1.4e-02 | -4.9 | 7.7 | 1.1e-14 | -0.74 | 0.05 | 0.66 | FALSE |
| 1 | GTEx | Artery Tibial | PSMC6 | 0.09 | 0.00 | lasso | 8 | 0.00 | 4.2e-01 | -7.3 | -7.5 | 5.8e-14 | 0.60 | 0.06 | 0.20 | FALSE |
| 5 | GTEx | Testis | RP11-368P15.3 | 0.10 | 0.00 | lasso | 3 | 0.00 | 2.6e-01 | -6.4 | 5.7 | 1.5e-08 | -0.64 | 0.06 | 0.48 | FALSE |