Best TWAS P=5.62e-17 · Best GWAS P=7.89e-26 conditioned to 1.71e-11
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | CARHSP1 | 0.38 | -0.01 | enet | 34 | 0.01 | 0.229 | -9.8 | -6.7 | 1.8e-11 | 0.52 | 0.03 | 0.61 | FALSE |
2 | GTEx | Brain Cerebellar Hemisphere | RP11-77H9.2 | 0.30 | -0.01 | lasso | 6 | 0.00 | 0.392 | -10.3 | -6.2 | 4.5e-10 | 0.48 | 0.04 | 0.34 | FALSE |
3 | GTEx | Skin Sun Exposed Lower leg | USP7 | 0.11 | 0.01 | enet | 13 | 0.01 | 0.054 | -10.2 | 8.4 | 5.6e-17 | -0.63 | 0.01 | 0.90 | TRUE |