TWAS hub - USP7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Muscle Skeletal	0.144	0.0436	0.00048	0.020	NA	0.014	NA	0.021	0.0038	NA	0.013	NA	0.0037
2	GTEx	Skin Sun Exposed Lower leg	0.111	0.0410	0.00260	0.006	NA	0.009	NA	0.001	0.0980	NA	0.054	NA	0.2800

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Friendships satisfaction	5.1	6.3	12.3	-3.5	0.4
Bipolar Disorder (2011)	5.0	4.8	5.7	2.0	-2.4
Family relationship satisfaction	5.0	6.1	11.9	-3.4	-0.6
Qualifications: nursing, teaching	4.4	6.8	8.8	-2.2	-3.0
Commuting to job workplace: Walk	3.4	3.7	7.1	-2.7	-0.4
Smoking Status	3.3	7.8	9.5	-3.1	2.5
Medication: Gliclazide	3.3	3.7	5.2	2.3	1.5
Number of operations (self-reported)	3.3	4.9	5.6	2.1	2.4
Blood Platelet Count	3.2	37.7	70.1	-2.3	8.4
Chronotype (morning person)	3.2	7.4	12.9	-3.6	1.4
Falls in the last year	3.2	4.4	6.3	2.5	1.6
Medication: Co-codamol	3.1	3.6	6.0	1.1	2.4
Ever had hysterectomy (womb removed)	2.9	3.2	6.2	2.5	-0.5
Happiness	2.9	3.5	6.4	-2.5	-0.8
Long-standing illness, disability or infirmity	2.9	4.5	8.6	0.6	2.9
Past tobacco smoking	2.8	5.2	5.7	2.4	-2.2
Breastfed as a baby	2.8	3.5	5.8	-2.4	1.1
Smoking status: Previous	2.8	4.2	5.0	-2.2	1.9
Alzheimer’s Disease (in father)	2.7	2.9	5.3	0.7	-2.3
Fractured/broken bones in last 5 years	2.7	3.5	4.3	-2.1	1.6
Medication: Atenolol	2.6	3.2	5.0	2.2	-1.2
Ever smoked	2.6	4.5	5.5	-1.9	2.3
Prostate Cancer	2.5	3.5	6.9	-0.4	2.6
Medication: Metformin	2.5	3.6	3.7	1.9	1.9
Diabetes (father)	2.5	3.1	5.9	-0.4	2.4
Had other major operations	2.5	3.1	6.1	-0.1	2.5
Pulse wave peak to peak time	2.5	2.9	3.7	1.4	-1.9
Comparative height size at age 10	2.5	14.0	26.5	1.2	-5.2
Unable to work because of sickness or disability	2.5	3.2	5.8	-0.8	2.4
Alzheimer’s Disease (in mother)	2.4	2.8	4.0	2.0	-1.3
Major Depression (MDD)	2.4	2.9	5.8	-2.4	-0.0
Type 2 Diabetes (T2D) (2018)	2.4	4.4	6.7	1.5	2.6
Other serious medical condition/disability diagnosed by doctor	2.4	3.1	3.3	-1.7	1.8
Worry too long after embarrassment	2.4	4.0	7.1	-2.7	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	2.4	2.8	3.5	1.4	-1.9
Qualifications: None of the above	2.3	4.9	9.0	3.0	0.9
Commuting to job workplace: Car/motor vehicle	2.3	2.6	2.7	1.6	1.6
Coronary Artery Disease (CAD)	2.2	2.6	2.9	1.7	-1.5
Diabetes (mother)	2.2	2.7	3.6	1.9	1.4
Exposure to tobacco smoke outside home	2.2	2.9	5.3	0.7	-2.3
Forced expiratory volume in 1-second (FEV1), predicted	2.2	4.7	8.5	-0.9	-2.9
Breast cancer (self-reported)	2.2	2.6	3.2	-1.8	1.4
Commuting to job workplace: Public transport	2.2	2.7	5.1	-2.3	-0.5
Basal cell carcinoma (self-reported)	2.2	2.7	3.5	-1.9	1.4
Neuroticism (2016)	2.1	3.0	4.5	-2.1	-1.3
Average weekly spirits intake	2.1	2.6	3.0	-1.5	1.7
Medication for cholesterol, blood pressure or diabetes	2.1	3.5	6.8	-0.4	-2.6
Mother’s age at death	2.1	2.6	4.9	0.5	-2.2
Bipolar Disorder (2018)	2.0	3.1	4.3	1.4	-2.1
Maternal smoking around birth	2.0	2.9	4.5	-2.1	-1.1
Age at first live birth	2.0	3.5	4.6	-1.6	-2.2
Age started oral contraceptive pill	2.0	2.5	3.9	1.0	-2.0
Qualifications: A levels/AS levels or equivalent	1.9	4.3	7.8	-2.8	-0.9
Handedness (chirality/laterality): Left-handed	1.9	2.3	4.1	-2.0	0.8
Tinnitus: Yes, now most or all of the time	1.9	2.2	3.1	1.8	1.1
Pulse wave Arterial Stiffness index	1.8	2.1	2.2	-1.4	1.5
Qualifications: College or University degree	1.8	5.8	10.5	-3.2	-1.1
Guilty feelings	1.8	2.7	5.3	-2.3	-0.5
Eye problems/disorders: Glaucoma	1.8	2.1	3.6	0.8	1.9
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	4.0	2.0	0.6
Standing height	1.7	17.2	33.6	-0.8	-5.8
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	4.3	-0.4	-2.1
Age at last live birth	1.7	2.5	2.8	-1.7	-1.5
Leg pain on walking	1.7	2.1	3.3	-1.0	1.8
Alzheimer’s Disease (including proxy)	1.6	2.4	3.5	1.1	-1.9
Hand grip strength (right)	1.6	4.3	8.5	-0.2	-2.9
Medication: Lansoprazole	1.6	1.8	3.6	1.9	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.0	9.2	-0.9	-3.0
Number of self-reported non-cancer illnesses	1.6	2.7	4.3	1.0	2.1
Medication: Atorvastatin	1.6	1.9	3.6	-0.4	1.9
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	3.1	1.8	-0.2
Number of full brothers	1.5	1.9	3.8	-1.9	-0.2
Loneliness, isolation	1.5	2.0	3.5	-1.9	0.8
Medication: Paracetamol	1.5	2.2	4.5	-0.0	2.1
Fasting Glucose	1.4	1.7	3.3	-1.8	-0.3
HDL Cholesterol	1.4	2.3	4.5	-2.1	0.1
Frequency of depressed mood in last 2 weeks	1.4	2.0	3.8	0.5	-1.9
Number of incorrect matches in round	1.4	2.3	3.9	2.0	-0.8
Forced vital capacity (FVC), Best measure	1.4	5.3	9.6	-1.0	-3.1
Medication: Seretide 50 evohaler	1.4	1.6	3.1	1.8	0.2
Diabetes diagnosed by doctor	1.4	2.3	3.6	1.0	1.9
Ever depressed for a whole week	1.4	1.8	2.0	1.2	-1.4
Commuting to job workplace: Cycle	1.4	1.7	1.9	-1.4	-1.2
Depression (Nagel 2018)	1.3	2.0	3.5	0.6	-1.9
Hand grip strength (left)	1.3	3.3	6.3	0.6	-2.5
Time employed in main current job	1.3	1.5	2.8	1.7	-0.3
Medication: Blood pressure	1.3	2.4	4.7	0.2	2.2
Financial situation satisfaction	1.3	1.6	2.0	-1.4	-1.1
Rheumatoid Arthritis	1.2	1.6	2.4	1.0	1.5
Cardiovascular Disease	1.2	4.1	7.4	0.9	2.7
Neuroticism	1.2	2.8	5.6	-2.4	-0.1
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.5	-0.0	1.6
Average weekly fortified wine intake	1.2	1.5	2.9	-0.0	1.7
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	2.8	1.7	0.3
Heart attack	1.2	1.6	2.0	1.4	-1.1
Father’s age at death	1.2	1.7	1.9	-1.4	-1.2
Medication: Paracetamol	1.2	2.0	4.0	-0.3	2.0
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	2.1	1.4	-0.9
Medication: Blood pressure	1.2	2.2	4.0	2.0	-0.6
Cholesterol lowering medication	1.2	1.7	2.0	1.4	1.2
Body Mass Index (BMI) (2010)	1.1	1.5	2.3	1.5	0.8
Height	1.1	21.0	42.0	-0.1	-6.5
Supplements: Glucosamine	1.1	1.5	2.5	-1.6	0.6
Leg fat percentage (right)	1.1	4.1	5.3	1.7	2.3
Medication: Omeprazole	1.1	1.3	2.3	1.5	0.6
Myopia	1.1	1.5	2.4	-0.8	1.6
Heart attack/myocardial infarction (self-reported)	1.1	1.4	1.7	1.3	-1.1
Schizophrenia vs Biploar Disorder	1.0	1.4	1.6	1.3	1.1
Crohns Disease (2012)	1.0	1.7	3.4	1.8	-0.0
Ulcerative Colitis	1.0	1.4	2.0	1.0	-1.4
Sensitivity / hurt feelings	1.0	1.7	2.7	1.7	0.8
Severe depression (siblings)	1.0	1.1	1.4	-1.2	-0.9
High blood pressure	1.0	2.8	3.9	1.3	2.0
Had menopause	1.0	1.3	2.0	1.4	-0.7
Forced vital capacity (FVC)	1.0	4.0	7.8	-0.4	-2.8
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	6.3	-0.7	-2.5
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	2.4	1.6	-0.1
Asthma	1.0	1.9	3.8	1.9	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	3.1	1.8	0.2
Pulse wave reflection index	1.0	1.2	2.3	-0.4	1.5
Heart disease (mother)	1.0	1.3	1.7	-1.3	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	1.6	0.8	1.3
Osteoarthritis (self-reported)	1.0	1.4	2.1	0.8	1.5
Medication: Lisinopril	1.0	1.3	1.8	1.3	0.9
Leg fat percentage (left)	1.0	3.5	5.2	1.3	2.3
Diastolic blood pressure, automated reading	1.0	3.0	3.0	1.7	1.7
Lupus	0.9	1.3	2.2	-1.5	0.6
Triglycerides	0.9	1.5	2.2	1.5	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	1.5	-1.2	-1.0
Exposure to tobacco smoke at home	0.9	1.0	1.4	-1.2	-0.8
Medication: Ventolin 100micrograms inhaler	0.9	1.1	1.3	1.0	-1.1
High blood pressure (siblings)	0.9	1.3	2.0	1.4	-0.8
Eye problems/disorders: None of the above	0.9	1.1	1.3	1.0	-1.1
Angina (self-reported)	0.9	1.2	1.8	0.8	-1.3
Overall health rating	0.9	1.9	3.4	0.5	1.9
Hypertension (Self-reported)	0.9	2.5	2.9	1.4	1.7
Medication for cholesterol	0.9	1.4	2.6	-1.6	-0.5
Illnesses of father: None of the above (group 1)	0.9	1.2	1.9	0.6	-1.4
Vascular/heart problems diagnosed by doctor	0.9	2.5	3.6	-1.2	-1.9
Heart disease (siblings)	0.9	1.1	2.0	-1.4	0.4
Alcohol drinker status: Previous	0.9	1.0	1.7	0.6	1.3
Blood Eosinophil Count	0.8	6.2	9.5	-3.1	1.7
Heel T-Score	0.8	6.4	10.5	3.2	-1.5
BMI	0.8	4.8	7.6	1.4	2.8
Age when periods started (menarche)	0.8	1.9	2.3	1.2	-1.5
Sitting height	0.8	5.5	10.0	-1.0	-3.2
High blood pressure (mother)	0.8	1.1	2.0	0.4	1.4
Alcohol usually taken with meals	0.8	1.3	1.5	-1.2	-1.0
Arm fat percentage (right)	0.8	3.3	6.5	0.2	2.5
Trunk predicted mass	0.8	4.5	8.8	0.3	-3.0
Birth weight of first child	0.8	1.5	2.7	-1.6	-0.6
Loud music exposure frequency	0.8	0.9	1.3	1.1	-0.8
Birth weight	0.8	1.8	3.5	-0.3	-1.9
Chest pain or discomfort	0.8	1.2	2.2	1.5	-0.4
Arm fat percentage (left)	0.8	3.0	5.7	0.6	2.4
Mineral and other dietary supplements	0.8	1.1	1.4	0.9	-1.2
Asthma (self-reported)	0.8	1.6	3.1	1.8	0.3
Bipolar Disorder or Schizophrenia	0.7	1.6	2.0	1.4	-1.1
HbA1C	0.7	0.8	1.5	-1.2	-0.1
Schizophrenia (2014)	0.7	1.6	2.4	1.6	-0.8
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.2	1.1	0.8
Angina	0.7	1.0	1.2	0.9	-1.1
Townsend deprivation index at recruitment	0.7	1.0	1.5	-1.2	0.7
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	1.5	0.5	1.2
Trunk fat-free mass	0.7	4.3	8.5	0.1	-2.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.3	-1.1	-0.7
Peak expiratory flow (PEF)	0.7	1.6	1.9	-1.1	-1.4
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	1.5	-1.2	1.0
Emphysema/chronic bronchitis	0.7	0.8	1.5	0.1	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.6	-1.3	-0.0
Pulse rate, automated reading	0.7	2.4	4.4	0.6	2.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	0.9	-0.9	0.9
Illnesses of siblings: Diabetes	0.7	0.8	1.0	0.8	1.0
Ever had bowel cancer screening	0.7	0.8	1.4	-0.3	1.2
Miserableness	0.7	1.2	1.9	0.7	-1.4
Alcohol drinker status: Never	0.7	0.9	1.6	1.2	0.4
Risk taking	0.7	1.0	1.3	0.9	-1.1
Age at First Birth	0.6	0.9	1.7	0.1	-1.3
Systolic blood pressure, automated reading	0.6	1.6	2.2	1.0	1.5
Fed-up feelings	0.6	1.0	2.0	-1.4	0.2
Body mass index (BMI)	0.6	2.7	3.9	1.2	2.0
Mouth/teeth dental problems	0.6	1.0	1.8	0.4	1.3
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	0.8	0.8	-0.9
Neuroticism score	0.6	1.3	2.6	-1.6	-0.3
Noisy workplace	0.6	0.7	1.1	-1.1	-0.5
Medication: Cholesterol lowering	0.6	0.9	1.8	0.3	1.3
Lung cancer (father)	0.6	0.7	1.2	-0.4	-1.1
Illnesses of mother	0.6	0.8	1.4	-1.2	0.3
Hair/balding pattern: Pattern 4	0.6	1.5	2.2	1.5	-0.9
Headache pain in last month	0.6	1.0	1.6	-0.6	-1.3
Medication: Amlodipine	0.6	0.9	1.6	0.4	1.3
Chronic bronchitis/emphysema (mother)	0.6	0.6	1.1	-1.1	0.4
Body fat percentage	0.6	2.4	3.9	0.9	2.0
Arm fat-free mass (right)	0.6	3.0	5.1	1.0	-2.3
Number of children fathered	0.6	0.7	1.4	-1.2	0.1
Shortness of breath walking on level ground	0.6	0.7	1.3	-0.1	1.1
Medication: Ibuprofen	0.6	0.8	1.3	-1.2	-0.5
Arm predicted mass (right)	0.6	3.3	5.6	1.0	-2.4
Supplements: Vitamin C	0.6	0.7	1.3	-1.1	-0.4
Illnesses of father: Heart disease	0.6	0.8	1.2	1.1	0.7
Whole body fat-free mass	0.6	3.2	6.3	0.1	-2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.2	-0.4	-1.5
Arm predicted mass (left)	0.6	3.0	4.8	1.1	-2.2
Primary Biliary Cirrhosis	0.5	0.7	0.9	-1.0	-0.7
Respiratory disease	0.5	1.2	2.3	1.5	0.3
Relative age of first facial hair	0.5	0.9	1.6	-0.5	1.3
Vitamin and mineral supplements	0.5	0.7	1.2	1.1	-0.5
Hair/balding pattern: Pattern 2	0.5	0.7	1.3	0.2	1.1
Allergy	0.5	1.1	2.1	-1.5	0.4
Diabetes (self-reported)	0.5	0.7	0.7	0.9	0.8
Depression (self-reported)	0.5	0.6	0.8	-0.6	0.9
Gout (self-reported)	0.5	0.7	0.8	-0.7	-0.9
Migraine (self-reported)	0.5	0.6	0.8	-0.6	-0.9
Leg fat mass (right)	0.5	2.1	2.9	1.7	1.1
Whole body water mass	0.5	2.8	5.7	0.1	-2.4
Average weekly champagne plus white wine intake	0.5	0.7	1.4	1.2	-0.3
Arm fat-free mass (left)	0.5	2.6	4.4	0.9	-2.1
Average weekly beer plus cider intake	0.5	0.7	1.3	-1.2	0.2
Pain experienced in last month	0.5	0.9	1.5	-0.5	1.2
Worry (Nagel 2018)	0.4	0.8	1.4	-0.4	-1.2
Verbal and Numeric Reasoning (VNR)	0.4	0.9	1.7	-1.3	0.2
Ovarian Cancer	0.4	0.5	1.0	-0.2	1.0
Waist circumference	0.4	1.6	1.7	1.3	1.2
Hearing difficulty/problems with background noise	0.4	0.7	1.0	-0.6	1.0
Pain all over the body in last month	0.4	0.4	0.7	0.4	0.8
Medication: Simvastatin	0.4	0.6	1.3	1.1	0.0
Tense / ‘highly strung’	0.4	0.7	1.4	0.2	-1.2
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.6	-0.7	0.7
Glaucoma (self-reported)	0.4	0.4	0.4	0.6	0.6
Wheeze or whistling in the chest in last year	0.4	0.6	1.0	1.0	0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.6	-0.6	0.8
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.1	-0.2	-1.1
Smoking status: Current	0.4	0.6	0.9	-1.0	0.5
Hearing aid user	0.4	0.4	0.5	-0.7	0.5
Basal metabolic rate	0.4	2.4	4.8	0.3	-2.2
Leg fat mass (left)	0.4	1.7	2.2	1.5	1.1
Neuroticism (Nagel 2018)	0.3	0.8	1.0	-0.7	-1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.7	-0.0	-0.8
Systolic Blood Pressure	0.3	1.3	1.4	1.1	1.2
Lung FVC	0.3	1.6	2.5	-1.6	0.9
Number of treatments/medications taken	0.3	0.5	0.6	0.7	0.8
Leg fat-free mass (left)	0.3	1.6	3.3	-0.1	-1.8
Trunk fat percentage	0.3	1.4	2.0	0.9	1.4
Serious illness, injury or assault to yourself	0.3	0.3	0.4	-0.5	0.6
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.1	0.6	-1.0
Multivitamins +/- minerals	0.3	0.4	0.6	-0.8	0.3
Stomach or abdominal pain in last month	0.3	0.4	0.7	0.9	0.4
Leg predicted mass (left)	0.3	1.7	3.3	-0.1	-1.8
Illnesses of siblings	0.3	0.4	0.5	-0.7	-0.6
Pulse rate	0.3	0.5	0.7	-0.6	0.8
Arm fat mass (right)	0.3	1.2	1.4	1.0	1.2
Whole body fat mass	0.3	1.1	1.2	1.1	1.0
Number of full sisters	0.3	0.4	0.8	0.9	-0.2
Suffer from ‘nerves’	0.3	0.4	0.7	0.8	0.4
Leg fat-free mass (right)	0.3	1.6	3.1	-0.5	-1.8
Average weekly red wine intake	0.3	0.5	0.7	-0.5	-0.8
Mood swings	0.3	0.6	1.1	-1.1	-0.1
Back pain experienced in last month	0.3	0.5	0.6	0.5	-0.8
Leg predicted mass (right)	0.3	1.7	3.1	-0.5	-1.8
Arm fat mass (left)	0.3	1.1	1.3	1.0	1.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.7	-0.9	0.3
High cholesterol (Self-reported)	0.3	0.5	0.5	0.7	0.7
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.8	-0.0	0.9
Supplements: Calcium	0.3	0.4	0.7	-0.8	0.0
Depressed Affect (Nagel 2018)	0.2	0.5	0.9	-0.4	-0.9
Intelligence (Savage-Jansen 2018)	0.2	0.5	0.9	-1.0	0.2
Crohns Disease (2017)	0.2	0.3	0.5	0.7	0.4
Reaction Time	0.2	0.3	0.6	-0.1	-0.8
Blood White Count	0.2	1.8	3.6	-0.2	1.9
Waist Hip Ratio (WHR)	0.2	1.1	1.5	0.8	1.2
Impedance of leg (right)	0.2	0.9	1.3	1.1	-0.8
Current tobacco smoking	0.2	0.4	0.6	-0.4	0.8
Relative age voice broke	0.2	0.3	0.6	0.8	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	0.7	0.8	0.2
Chronic bronchitis/emphysema (father)	0.2	0.3	0.5	-0.7	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	0.6	0.7	0.8
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.4	-0.2	-0.6
Financial difficulties in last 2 years	0.2	0.3	0.6	0.8	0.2
Fluid intelligence score	0.2	0.4	0.7	-0.9	0.2
Impedance of arm (right)	0.2	1.1	2.2	-1.5	-0.0
Worrier / anxious feelings	0.2	0.3	0.4	-0.5	-0.6
Mouth/teeth dental problems: Dentures	0.2	0.3	0.7	-0.0	0.8
Prospective memory result	0.2	0.3	0.4	0.4	-0.6
Length of working week for main job	0.2	0.2	0.3	-0.1	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	0.0	0.8
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.5	0.7	-0.2
Schizophrenia (2018)	0.1	0.3	0.5	0.7	0.2
Irritable Bowel Disease (IBD)	0.1	0.2	0.3	0.6	0.0
Ulcerative Colitis (UC)	0.1	0.2	0.3	0.3	-0.6
Breast Cancer	0.1	0.3	0.5	0.7	-0.3
Mean Putamen Volume	0.1	0.1	0.1	0.0	0.3
LDL Cholesterol	0.1	0.1	0.3	-0.0	0.5
Allergy or Eczema	0.1	0.1	0.1	-0.4	-0.4
Hypothyroidism (self reported)	0.1	0.2	0.3	-0.6	-0.0
Hearing difficulty/problems: Yes	0.1	0.2	0.3	-0.4	0.5
Taking other prescription medications	0.1	0.1	0.1	0.3	0.4
Qualifications: CSEs or equivalent	0.1	0.2	0.3	-0.5	0.3
Medication: Levothyroxine sodium	0.1	0.2	0.3	-0.5	0.2
Impedance of leg (left)	0.1	0.6	0.7	0.7	-0.8
Trunk fat mass	0.1	0.6	0.7	0.9	0.7
Nervous feelings	0.1	0.2	0.2	-0.5	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.2	-0.7
Medication: Ramipril	0.1	0.1	0.2	0.2	-0.4
Weight	0.1	0.4	0.4	0.6	-0.6
Hip circumference	0.1	0.5	0.9	1.0	-0.2
Alcohol intake versus 10 years previously	0.1	0.2	0.4	-0.2	-0.6
Hair/balding pattern: Pattern 3	0.1	0.1	0.2	0.2	-0.4
Number of live births	0.1	0.1	0.2	0.2	0.4
Impedance of arm (left)	0.1	0.6	1.0	-1.0	-0.4
Blood clot in the leg (DVT)	0.1	0.1	0.2	0.4	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.3	-0.5	0.1
Medication for pain relief, constipation, heartburn	0.1	0.2	0.3	0.5	-0.2
Neck or shoulder pain in last month	0.1	0.1	0.1	0.3	-0.3
Medication: Allopurinol	0.1	0.2	0.3	0.1	-0.6
Mean time to correctly identify matches	0.1	0.2	0.3	0.2	-0.6
Alcohol intake frequency.	0.1	0.2	0.3	0.5	0.4
Had major operations	0.1	0.1	0.2	0.2	0.5
Medication: Aspirin	0.1	0.2	0.3	-0.2	-0.6
Knee pain experienced in last month	0.1	0.2	0.3	-0.1	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.1	-0.4	0.3
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.5	-0.3
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.4	0.2
Medication: Aspirin	0.1	0.1	0.3	-0.1	-0.5
Wears glasses or contact lenses	0.1	0.2	0.3	-0.2	0.5
Medication: Bendroflumethiazide	0.1	0.2	0.3	0.6	0.1
Pack years of smoking	0.1	0.1	0.1	-0.3	-0.3
Blood Red Count	0.0	0.3	0.3	0.5	-0.6
Lung FEV1/FVC ratio	0.0	0.1	0.1	0.2	0.2
Hair Pigment	0.0	0.9	1.7	1.3	0.1
Tanning	0.0	0.0	0.1	-0.1	-0.2
Medication for hormone replacement therapy	0.0	0.1	0.1	-0.1	0.3
Supplements: Zinc	0.0	0.0	0.1	0.0	0.2
Pack years adult smoking proportion	0.0	0.1	0.1	-0.1	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.1	-0.3	-0.1
Comparative body size at age 10	0.0	0.1	0.1	0.1	0.4
Health satisfaction	0.0	0.1	0.1	-0.3	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.0	-0.1	-0.0
Ever taken oral contraceptive pill	0.0	0.1	0.1	-0.2	0.2
Pain type(s) experienced in last month: Hip pain	0.0	0.0	0.0	-0.1	-0.0
Illnesses of father: High blood pressure	0.0	0.0	0.0	0.2	-0.1
Irritability	0.0	0.1	0.1	-0.3	0.1
Impedance of whole body	0.0	0.2	0.3	-0.2	-0.6

Hub : Genes

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Trait associations