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chr16:67,872,251-70,473,934

Best TWAS P=1.52e-11 · Best GWAS P=1.74e-11 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Testis	ZFP90	0.14	0.14	lasso	5	0.11	1.0e-05	6.7	6.8	1.5e-11	0.97	0.02	0.98	TRUE
7	GTEx	Nerve Tibial	NOB1	0.10	0.08	enet	8	0.08	1.9e-06	3.1	-6.2	7.2e-10	-0.04	0.03	0.94	TRUE
11	GTEx	Whole Blood	ZFP90	0.13	0.09	lasso	5	0.14	5.6e-13	6.4	-6.8	1.5e-11	-0.83	0.05	0.95	FALSE
12	METSIM	Adipose	ZFP90	0.09	0.06	lasso	7	0.07	3.0e-11	6.3	-6.7	1.7e-11	-0.95	0.04	0.96	FALSE
3	GTEx	Brain Hypothalamus	ZFP90	0.17	0.13	lasso	7	0.09	5.0e-03	6.4	6.7	2.7e-11	0.91	0.04	0.84	FALSE
13	NTR	Blood	ZFP90	0.07	0.07	enet	14	0.07	9.4e-22	6.5	-6.7	2.7e-11	-0.94	0.03	0.97	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	ZFP90	0.10	0.08	blup	33	0.09	8.3e-04	5.6	6.5	6.1e-11	0.80	0.02	0.77	FALSE
4	GTEx	Cells Transformed fibroblasts	ZFP90	0.12	0.05	enet	7	0.04	2.7e-04	6.5	6.5	7.9e-11	0.87	0.02	0.98	FALSE
2	GTEx	Brain Cortex	ZFP90	0.20	0.09	lasso	4	0.13	2.3e-04	6.5	6.4	1.6e-10	0.85	0.04	0.89	FALSE
6	GTEx	Muscle Skeletal	ZFP90	0.07	0.06	lasso	10	0.04	4.6e-05	6.3	-6.4	1.6e-10	-0.91	0.05	0.95	FALSE
14	YFS	Blood	ZFP90	0.43	0.46	enet	35	0.48	2.1e-184	6.3	-6.3	2.2e-10	-0.89	0.08	0.92	FALSE
9	GTEx	Spleen	ZFP90	0.31	0.25	lasso	9	0.22	3.0e-06	6.3	-6.2	4.6e-10	-0.86	0.05	0.92	FALSE
8	GTEx	Nerve Tibial	CTD-2033A16.3	0.13	0.04	enet	16	0.07	1.7e-05	3.1	-6.1	8.2e-10	-0.07	0.01	0.98	FALSE
5	GTEx	Lung	ZFP90	0.11	0.07	enet	21	0.06	2.4e-05	6.3	-6.0	1.9e-09	-0.72	0.06	0.93	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CDH1	0.08	0.09	lasso	6	0.09	8.9e-11	5.8	5.8	5.9e-09	0.65	0.05	0.95	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZFP90	0.10	0.16	lasso	2	0.16	1.5e-17	5.6	5.6	2.7e-08	0.53	0.71	0.29	FALSE