Best TWAS P=6.57e-11 · Best GWAS P=4.54e-08 conditioned to 0.751
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CCDC102A | 0.16 | 0.09 | enet | 27 | 0.11 | 2.9e-13 | -5.5 | 6.5 | 6.6e-11 | -0.80 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Brain Cerebellum | SETD6 | 0.37 | 0.27 | lasso | 7 | 0.25 | 4.5e-08 | -4.9 | 5.5 | 3.6e-08 | -0.01 | 0.02 | 0.98 | TRUE |
| 3 | GTEx | Muscle Skeletal | CCDC102A | 0.10 | 0.08 | enet | 6 | 0.06 | 7.0e-07 | -5.5 | 5.5 | 3.3e-08 | -0.98 | 0.00 | 1.00 | FALSE |
| 4 | YFS | Blood | SETD6 | 0.14 | 0.10 | bslmm | 457 | 0.13 | 1.1e-39 | -4.9 | 5.3 | 1.0e-07 | -0.04 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CCDC102A | 0.05 | 0.05 | lasso | 4 | 0.05 | 2.5e-06 | -5.5 | 5.8 | 6.1e-09 | -0.98 | 0.00 | 1.00 | FALSE |