Best TWAS P=2.24e-08 · Best GWAS P=2.56e-228 conditioned to 6.46e-225
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | AKAP8 | 0.32 | 0.39 | lasso | 5 | 0.39 | 5.5e-51 | 5.6 | 5.6 | 2.6e-08 | -0.07 | 1.00 | 0.00 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | AKAP8 | 0.27 | 0.32 | bslmm | 553 | 0.33 | 2.0e-43 | 5.5 | 5.5 | 3.2e-08 | -0.06 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | WIZ | 0.02 | 0.03 | enet | 4 | 0.03 | 1.1e-03 | 5.7 | -5.6 | 2.2e-08 | 0.05 | 0.02 | 0.94 | TRUE |